Koj puas tau xav tias koj yuav muaj ntshav txhaws? Los yog koj puas tau xav tias koj txhais ceg o thiab mob? Qhov laj thawj rau tej yam no yuav txawv ntawm koj xav. Niaj hnub no peb tab tom tham txog ib qho mob tsis tshua muaj tab sis tseem ceeb heev uas yuav tsum paub txog. Qhov ntawd yog Protein C Deficiency . Txawm hais tias lub npe yuav zoo li txawv txawv, nws muaj feem cuam tshuam rau cov txheej txheem ntshav txhaws hauv peb lub cev. Cia peb saib seb nws yog dab tsi, vim li cas nws tshwm sim, thiab koj tuaj yeem ua dab tsi txog nws.
Qhov tsis txaus ntawm Protein C yog dab tsi tiag?
Hais yooj yim xwb, Protein C Deficiency yog ib qho mob uas peb cov ntshav txhaws ntau dua li qhov nws xav tau, lossis ua rau tsis zoo li qub. Nov yog ib qho lus piav qhia luv luv.
Xav txog tias koj muaj ib qho qhov txhab nyob rau ntawm koj lub cev. Tom qab ntawd, kom tsis txhob los ntshav, yuav tsum muaj cov ntshav txhaws. Qhov ntawd yog ib txwm muaj. Nws yog peb lub cev txoj kev tiv thaiv. Tab sis yuav ua li cas yog tias cov ntshav txhaws no tsis tuaj yeem tswj tau thiab ntau dhau? Qhov ntawd yog qhov teeb meem pib.
Muaj ntau yam ntuj tsim nyob hauv peb cov ntshav uas tswj cov txheej txheem ntshav txhaws no, zoo li lub tshuab nres ntawm lub tsheb. Protein C yog ib qho zoo li no, ib qho protein tseem ceeb heev uas tswj cov ntshav txhaws. Qhov no hu ua ib yam khoom ntuj 'tiv thaiv kev txhaws' lossis tshuaj anticoagulant . Ntawd yog, ib yam khoom uas tiv thaiv cov ntshav kom tsis txhob txhaws.
Tam sim no koj nkag siab lawm, puas yog? Kev tsis txaus Protein C txhais tau tias koj tsis muaj cov protein no txaus hauv koj cov ntshav. Thaum qhov ntawd tshwm sim, lub nres uas tswj cov ntshav txhaws tsis ua haujlwm zoo. Qhov tshwm sim yog tias cov ntshav txhaws pib tsim hauv cov hlab ntsha. Cov ntshav txhaws uas tsim los ntawm txoj kev no tuaj yeem ua rau muaj kev phom sij heev, txawm tias muaj kev phom sij rau lub neej. Piv txwv li, cov ntshav txhaws tsim nyob rau hauv cov leeg ntshav tob ntawm ob txhais ceg (Deep Vein Thrombosis) thiab cov mob zoo li cov ntshav txhaws tawg thiab daig hauv lub ntsws (Pulmonary Embolism) .
Tus mob no feem ntau tshwm sim li cas?
Qhov no yeej tsis yog ib yam uas tshwm sim ntau heev, tab sis nws tsis tshua muaj li peb xav.
- Hom mob me me: Kwv yees li qhov no tsuas yog cuam tshuam rau ib tus neeg ntawm 200 txog 500 tus neeg hauv cov pej xeem feem ntau.
- Hom mob hnyav: Qhov no yog hom mob tsawg tshaj plaws. Nws cuam tshuam li ib ntawm 500,000 txog 750,000 tus neeg. Txawm li cas los xij, tus lej tseeb yuav siab dua li cov kev kwv yees no.
Tus mob no cuam tshuam rau txiv neej thiab poj niam sib npaug zos.
Cov tsos mob ntawm qhov no yog dab tsi?
Cov tsos mob ntawm tus kab mob no sib txawv nyob ntawm seb nws puas mob me me lossis mob hnyav. Cia peb saib daim ntawv teev lus hauv qab no kom nkag siab qhov no kom meej.
| Xwm txheej ntawm tus kab mob | Cov tsos mob uas pom tau |
|---|---|
| Hom me me |
|
| Hom mob hnyav |
Cov ua rau muaj qhov tsis txaus ntawm Protein C yog dab tsi?
Qhov laj thawj tseem ceeb rau qhov mob no yog kev cuam tshuam los ntawm caj ces, uas txhais tau tias nws yog ib yam dab tsi uas tau kis los ntawm ib tiam dhau ib tiam.
Cov Ua Rau Los Ntawm Keeb Kwm
Muaj ib tug noob caj noob ces hauv peb lub cev uas qhia peb kom ua ib tug protein hu ua Protein C. Nws hu ua PROC gene . Yog tias muaj kev hloov pauv hauv cov noob caj noob ces no, Protein C tej zaum yuav tsis tau tsim kom zoo, lossis txawm tias nws tau tsim los, nws tej zaum yuav tsis ua haujlwm kom zoo.
- Hom I Tsis Txaus: Qhov no yog tshwm sim los ntawm kev txo qis ntawm cov Protein C.
- Hom II Tsis Txaus: Qhov no tshwm sim thaum cov protein C theem zoo li qub, tab sis cov protein tsis ua haujlwm zoo.
Xav txog tias ib tug ntawm cov niam txiv muaj cov noob caj noob ces PROC uas hloov pauv no. Tom qab ntawd muaj 50% feem pua uas tus menyuam uas lawv muaj yuav tau txais cov noob caj noob ces hloov pauv ntawd. Yog tias qhov ntawd tshwm sim, tus menyuam yuav muaj tus kab mob no me me.
Tam sim no xav txog tias ob leeg niam txiv muaj cov noob caj noob ces hloov pauv no. Tom qab ntawd muaj 25% feem pua uas tus menyuam yuav tau txais ob qho noob caj noob ces hloov pauv ntawd. Tus menyuam ntawd yuav muaj tus mob hnyav uas qhia cov tsos mob thaum yug los.
Cov laj thawj tau txais
Qhov no tsis yog ib txwm yog los ntawm noob caj ces. Qee yam mob lossis lwm yam ua rau kuj ua rau muaj Protein C tsawg.
- Tsis muaj Vitamin K txaus
- Siv cov tshuaj Warfarin uas ua rau cov ntshav nyias (peb mam tham txog qhov no tom qab)
- Kab mob siab loj heev
- Ib qho mob hu ua Disseminated Intravascular Coagulation (DIC)
- Kab mob loj heev (Sepsis)
Yuav kuaj mob li cas?
Yog koj tus kws kho mob xav tias koj muaj tus kab mob no, lawv yuav kuaj ntau yam kom paub tseeb tias koj muaj tus kab mob no.
- Koj keeb kwm kev mob nkeeg: Seb koj puas tau muaj teeb meem ntshav txhaws ua ntej.
- Koj tsev neeg keeb kwm kev mob nkeeg: Puas muaj leej twg hauv koj tsev neeg muaj cov teeb meem ntshav txhaws no?
- Kev kuaj ntshav: Qhov no yog qhov tseem ceeb tshaj plaws. Lawv ntsuas koj cov Protein C kev ua haujlwm thiab Protein C theem hauv koj cov ntshav.
- Kev kuaj noob caj noob ces: Kev kuaj noob caj noob ces tuaj yeem ua tau los xyuas seb puas muaj kev hloov pauv hauv cov noob caj noob ces PROC. Txawm li cas los xij, qhov no tsis tsim nyog los paub meej tias muaj tus kab mob.
Yuav kho li cas?
Kev kho mob nyob ntawm seb koj muaj hom Protein C Deficiency li cas thiab qhov hnyav ntawm koj cov tsos mob.
Kev kho mob rau daim ntawv me me
- Feem ntau cov neeg tsis xav tau kev kho mob: Feem ntau cov neeg tsis xav tau kev kho mob. Txawm li cas los xij, kev saib xyuas tshwj xeeb thiab tej zaum yuav xav tau kev kho mob thaum lub sijhawm phais, thaum cev xeeb tub, yog tias lawv muaj xwm txheej loj (piv txwv li, xwm txheej tsheb), lossis thaum lub sijhawm tsis ua ub ua no (piv txwv li, yog tias lawv raug kaw hauv txaj).
- Cov Tshuaj Anticoagulants: Yog tias koj twb muaj teeb meem thrombotic lawm, koj tus kws kho mob yuav sau ntawv rau koj cov tshuaj anticoagulants.
Tseem ceeb heev: Yog tias koj noj tshuaj zoo li Warfarin, koj yuav tsum tau txhaj tshuaj hu ua Heparin ua ntej nws. Yog tias koj tsis ua, nws qee zaum tuaj yeem ua rau muaj teeb meem loj xws li ntshav txhaws hauv daim tawv nqaij thiab lwm qhov chaw. Tab sis muaj cov tshuaj tshiab uas tsis xav tau qhov no. Txawm koj siv tshuaj dab tsi los xij, koj tus kws kho mob yuav saib xyuas nws tas li. Nco ntsoov, tsis txhob tsum noj cov tshuaj uas koj tus kws kho mob tau sau rau koj tus kheej. Yog tias koj muaj teeb meem dab tsi, tham nrog koj tus kws kho mob. Yog tias koj muaj teeb meem dab tsi, xws li los ntshav ntau, hu rau koj tus kws kho mob tam sim ntawd.Mus rau Chav Kho Mob Thaum Muaj Xwm Ceev (ETU).
Kev kho mob rau daim ntawv hnyav
Rau qhov mob hnyav no rau cov menyuam mos, kev kho mob tshwj xeeb hu ua Protein C concentrate (Ceprotin®) lossis cov plasma khov tshiab raug muab.
Qhov no ua rau muaj teeb meem dab tsi?
Muaj ntau yam teeb meem loj uas tuaj yeem tshwm sim los ntawm tus mob no.
- Cov teeb meem ntawm daim tawv nqaij uas cuam tshuam nrog Warfarin: Tom qab pib noj warfarin, qee tus neeg yuav muaj cov qhov txhab mob, liab lossis ntshav. Cov no feem ntau tshwm sim rau ntawm lub cev sab saud, caj npab lossis ceg. Yog tias tsis kho kom zoo, qhov no tuaj yeem ua rau daim tawv nqaij thiab cov nqaij hauv qab tuag.
- Kab mob ntsws txhaws: Cov ntshav txhaws uas tsim nyob rau hauv ob txhais ceg (cov hlab ntsha tob tob) tuaj yeem tawg tawm, mus ncig hauv cov ntshav, thiab nkag mus rau hauv cov hlab ntsha hauv lub ntsws. Qhov no yog ib qho mob uas txaus ntshai rau lub neej.
- Purpura Fulminans: Teeb meem ntshav txhaws thoob plaws lub cev ntawm tus menyuam mos. Yog tias tsis kho, nws tuaj yeem ua rau tuag taus.
- Cov Teeb Meem ntawm Kev Kho Mob Ntshav Tshiab: Thaum cov menyuam mos tau txais kev kho mob no tas li, cov teeb meem tuaj yeem tshwm sim vim muaj cov kua dej ntau ntxiv hauv lub cev (cov kua dej ntau dhau).
Tom qab kuaj pom tias muaj tus kab mob no lawm, koj yuav tau txais dab tsi?
Qhov tshwm sim ntawm qhov no sib txawv heev nyob ntawm qhov hnyav ntawm tus kab mob.
Qhov kev kwv yees rau cov menyuam mos uas muaj Protein C Deficiency hnyav tsis zoo. Lawv tej zaum yuav tuag sai tom qab yug los. Tseem tsis tau muaj cov ntaub ntawv txaus los hais tias cov neeg uas muaj tus mob hnyav no yuav muaj sia nyob ntev npaum li cas.
Yog koj muaj mob hnyav me ntsis, koj muaj feem yuav mob ntshav txhaws rov qab los. Kuj tseem muaj feem yuav mob ntshav txhaws mus rau hauv lub ntsws. Yog xav tau qhov zoo tshaj plaws, nws yog ib qho tseem ceeb uas yuav tsum mus ntsib koj tus kws kho mob raws sijhawm. Qhov no yuav cia nws saib xyuas koj tus mob kom zoo thiab kho koj txoj kev kho mob raws li qhov xav tau.
Qhov no puas tiv thaiv tau?
Vim tias qhov tsis txaus Protein C feem ntau yog los ntawm noob caj ces, nws tsis tuaj yeem tiv thaiv tau. Txawm li cas los xij, cov niam txiv thiab cov menyuam tuaj yeem sab laj nrog kws kho mob ntshav kom paub ntau ntxiv txog qhov no thiab ua cov kev kuaj mob tsim nyog.
Tsis tas li ntawd xwb, qee zaum kev tsis txaus Protein C uas tshwm sim los ntawm lwm yam mob kuj tuaj yeem tiv thaiv tau. Piv txwv li,
- Cov tshuaj estrogen nyob rau hauv qee cov tshuaj tswj kev yug me nyuam uas cov poj niam noj tuaj yeem ua rau muaj kev pheej hmoo ntawm cov ntshav txhaws.
- Qhov kev pheej hmoo no ntxiv zuj zus los ntawm tej yam xws li kev haus luam yeeb, kev rog dhau, cev xeeb tub, thiab kev tsis ua ub ua no.
Muaj tej lub sij hawm, koj tus kws kho mob yuav sau ntawv kom koj noj cov tshuaj anticoagulants kom tiv thaiv tau qhov kev pheej hmoo no. Yog li ntawd, nws yog ib qho tseem ceeb heev uas yuav tsum tham nrog koj tus kws kho mob txog koj tej yam uas ua rau koj muaj kev pheej hmoo.
Cov Lus Qhia Txog Kev Coj Mus Tsev
- Kev tsis txaus Protein C yog ib qho mob uas ua rau cov ntshav txhaws tsis zoo, feem ntau yog los ntawm noob caj noob ces.
- Muaj ob hom mob no, mob me me thiab mob hnyav. Coob leej neeg uas mob me me tsis qhia tsos mob.
- Yog koj muaj cov tsos mob xws li o thiab mob ceg, tej zaum nws yog kab mob ntshav hauv cov leeg ntshav tob (DVT). Tsis txhob tsis quav ntsej txog qhov no.
- Yog tias tsim nyog kho mob, ua raws li koj tus kws kho mob cov lus qhia kom meej. Tsis txhob tsum lossis hloov koj cov tshuaj ntawm koj tus kheej.
- Yog tias koj muaj tus mob no, nws yog ib qho tseem ceeb heev uas yuav tsum nyob deb ntawm cov yam uas ua rau koj muaj feem yuav mob xws li haus luam yeeb thiab rog dhau.
- Yog tias muaj leej twg hauv koj tsev neeg muaj tus kab mob no, nws yog ib qho zoo rau koj mus ntsib kws kho mob kom tau txais kev qhia thiab, yog tias tsim nyog, mus kuaj mob.
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Tsis muaj lus teb tau muab tso tawm. Ntxiv koj cov lus tawm ntawm no thawj zaug.
Ntxiv koj cov lus