Yu pletlɛt dɛn bɔku? Lɛ wi tɔk bɔt Trombocytosis!

Dɛn dɔn no bak se yu gɛt bɔku pletlɛt dɛn na yu blɔd? Ɔ pɔsin we yu sabi gɛt dis sik? Na nɔmal tin fɔ fil smɔl we yu yɛri sɔntin lɛk dis. Bɔt nɔr wɔri, tide wi go tɔk bɔt dis sik we dɛn kɔl Thrombocytosis insay wan simpul we we yu go ɔndastand.

Wetin na trombosaytɔsis? Simply put am...

Fɔ tɔk am simpul wan, trombocytosis na we yu gɛt bɔku bɔku pletlɛt dɛn na yu blɔd. Naw yu go de aks se, “Wetin na pletlɛt?” Dat na kwɛstyɔn we rili impɔtant!

Plɛtlɛt na wan kayn smɔl smɔl sɛl we de na wi blɔd. Dɛn men wok na fɔ stɔp fɔ blɔd we blɔd de kɔmɔt, lɛk we wund de. Dɛn kin biev lɛk smɔl dɛm.

Bɔt wetin kin apin if di nɔmba fɔ di pletlɛt dɛn bɔku pasmak? Yu blɔd kin tik ɛn stika. Sɔntɛnde, dɛn pletlɛt ya we pasmak kin mek blɔd klɔt we denja fɔ mek insay di blɔd vesel dɛn. Dis kin mek yu gɛt bɔku prɔblɛm dɛn lɛk strok ɔ at atak .

Bɔt nɔto ɔl di kes dɛm we gɛt Thrombocytosis na di sem denja. Aw de sik kin tranga, ɛn if yu nid tritmɛnt ɔr nɔr nid tritmɛnt, kin dipen pan de kɔz.

Tu men kayn trombosaytosis de:

Yɛs, dɔktɔ dɛn dɔn no tu men kayn sik ya. Lɛ wi tɔk bɔt dat smɔl.

1. Essential Thrombocythemia (ET) ɔ Praymari Trombosaytosis

Dis na wan sik we nɔ kin apin to blɔd. i kin apin we yu bon mכro – di bכdi sεl fכktכri insay yu bon dεm – de mek tu mכch pletlet dεm. Tink bɔt am, bɔku pan di blɔd sɛl dɛn na wi bɔdi na dis bon mɛro dɛn mek am. Pɔsin we gɛt impɔtant trombosaytemia gɛt abnɔmal ay prodakshɔn fɔ pletlɛt bikɔs ɔf wan difrɛns na dis blɔd sɛl prodakshɔn prɔses.

Dɛn kin tek dis sik we dɛn kɔl ET (Essential Thrombocythemia) , as di sik we kin bɔku pas ɔl na di blɔd grup we dɛn kɔl Myeloproliferative Neoplasm (MPN) .

2. Riaktiv Trombosaytosis ɔ Sɛkɔndari Trombosaytosis

Dis na di kayn we we dɛn kin kɔl Trombocytosis we kin apin mɔs. Dis na we yu bɔdi de mek mɔ pletlɛt fɔ ansa to ɔda kɔndishɔn, infɛkshɔn, injuri, ɔpreshɔn, ɔ pul di splin. Fɔ tɔk am simpul wan, yu bɔdi kin du ɔda tin ɛn i kin mek in pletlɛt dɛn go ɔp. Disrεaktiv trombosaytosis kin bi fכ sכm tεm, we min se wans di כndalayn kכz dεn rεsכlv, di pletlet kכnt de kam bak to nכmal.

Udat kin gɛt trombosaytɔsis?

Dɛn kin no dis sik mɔ pan pipul dɛm wae dɔn pas 60. Dɔn bak, dɛn kin ripɔt se dɛn kin no wan kayn sik we dɛn kɔl Essential Thrombocythemia (ET) pan uman dɛm tu tɛm pas man dɛm.

Wetin na di tin dɛn we kin mek pɔsin gɛt trombosaytɔsis?

Di rizin dɛn bak fɔ di tu kayn we dɛn we wi bin dɔn tɔk bɔt, difrɛn bak.

Di tin dɛn we kin mek pɔsin gɛt Essential Thrombocythemia (ET) .

Essential Thrombocythemia (ET) na wan kכndyushכn we dεn kin gεt jεnεtik. I nɔto sɔntin we dɛn bɔn yu wit. I kin kam bikɔs sɔm jin dɛn we kin mek di pletlɛt dɛn kin chenj ɔ we kin chenj . Dis kin mek yu bon mɛrɔ de mek bɔku bɔku pletlɛt dɛn.

mכr dan haf pan di pipul dεm we gεt Essential Thrombocythemia (ET) gεt mכtεshכn na di JAK2 jin. mכtεshכn dεm na di CALR כ MPL jin dεm dεn tu kכmכn.

Sayɛnsman dɛn stil nɔ ebul fɔ no klia wan wetin kin mek dɛn jin dɛn ya chenj, bɔt dɛn de kɔntinyu fɔ du risach bɔt am.

Di tin dɛn we kin mek pɔsin gɛt Riaktiv Trombosaytɔsis

Dis kayn kin apin bikɔs yu bɔdi de mek mɔ pletlɛt dɛn we i de ansa difrɛn tin dɛn. Ɔ, sɔmtɛm, i kin bi bak bikɔs ol pletlɛt dɛn kin gɛda instead fɔ pwɛl dɛn di nɔmal rit.

Na sɔm tin dɛm wae kin mek yu gɛt Riaktiv Trombosaytosis :

• Anemia , mɔ di wan dɛn we nɔ gɛt ayɔn .
• Ɔda prɔblɛm dɛn we kin apin na blɔd.
• Sɔm kayn kansa dɛn .
• Infɛkshɔn dɛn, lɛk nyumonia .
• Inflammatory conditions – kכndishכn dεm we de mek inflameshn na di bכdi, lεk rεumatoid arthritis.
• Wund .
• Kidni we nɔ de wok fayn .
• Sɔm mɛrɛsin dɛn.
• Ɔpreshɔn, mɔ ɔpreshɔn pan bɛlɛ.
• Fɔ pul di splin .
• Fɔ trit di wan dɛn we nɔ gɛt vaytamɛn B12 .

Dis list jɔs gɛt sɔm tin dɛn we kin mek pɔsin gɛt prɔblɛm. Bɔku ɔda tin dɛn kin de we kin mek pɔsin gɛt Riaktiv Thrombocytosis .

Wetin na di sayn dɛm fɔ trombosaytɔsis?

Bɔrku tɛm, pipul dɛm wae gɛt bɔrku pletlet nɔr kin gɛt ɛni sayn, at ɔl nɔr kin gɛt di fɔs stej. If yu gɛt Reactive Thrombocytosis , yu kin gɛt sɔm sayn dɛm fɔ de ɔndalayn mɛdikal kɔndishɔn wae mek yu gɛt am.

Bɔt we di sayn dɛn kin apin, bɔku tɛm dɛn kin gɛt fɔ du wit di blɔd we nɔ de kɔmɔt fayn ɛn we blɔd kin klɔt na yu bɔdi. Yu kin si sayn dɛm lɛk:

• Ed de at .
• I izi fɔ mek i brus.
• Fɔ fil wik, diziz, ɔ layt ed.
• Blɔd we de kɔmɔt na di nos, mɔt, ɛn di gɔm.
• Blɔd we de kɔmɔt na di bɛlɛ ɔ insay di bɔdi.

Sɔm pipul dɛm wae gɛt Essential Thrombocythemia (ET) kin gɛt wan sik wae dɛn kɔl Erythromelalgia . Dis kin mek yu an ɛn fut de fil pen, swel, ɛn rɛd. Dɛn kin gɛt bak swɛt ɛn swɛt na dɛn an ɛn fut.

if i bad, trombosaytosis kin mek di bכdi kכlכt we nכ nכmal na di bכdi (e.g., Budd-Chari syndrome ) εn i kin mek di risk f כ strכ k כ hat atak bכku .

Aw dɛn kin no se pɔsin gɛt trombosaytɔsis?

biכs trombosaytosis nכ kin kכz di simptom dεm, di fכs klyu we yu gεt na if wan rutin bכdi tεst (e.g., Complete Blood Count – CBC ) sho se di pletlet kכnt de inkrεs.

dεn dεfεn trombosaytosis as i gεt pas 450,000 pletlet dεm pan wan maykrolit bכdi. If yu pletlɛt bɔku, i go mɔs bi se yu dɔktɔ go tɛl yu fɔ du ɔda blɔd tɛst insay sɔm wiks fɔ si if di lɛvɛl stil de ɔp. If di pletlɛt dɛn bɔku wan tɛm ɛn afta dat i go bak to nɔmal, dat nɔ kin bi prɔblɛm. Bɔt if yu kɔntinyu fɔ gɛt ay ay lɛvɛl, dat kin sho se yu gɛt wan sik we de ɔnda am.

insay di kes f כ riaktiv trombosaytosis , fכ no di כndalayn kכndyushכn we kכz am (e.g., ayron dεfisiεns anemia , kεnsar, infεkshכn) kin εp dכkta dεm fכ no εn mεnεj am. Bɔt if di dɔktɔ nɔ ebul fɔ fɛn dis kayn sɛkɔndari kɔz, dɛn go du ɔda tɛst fɔ si if yu gɛt Essential Thrombocythemia (ET) .

Dɛn tɛst ya kin bi:

• Pɛriferal blɔd smyuɛl:Dis kin chɛk fɔ si if di pletlɛt dɛn we de na yu blɔd nɔ de luk fayn.
• DNA/jεnεtik tεst dεm: dis kin no di jεnεtik mכtεshכn dεm lεk JAK2 , we kכmכn fכ ET (Essential Thrombocythemia) .
• Bon mכro bayopsi: Dis de chεk yu bon mכro fכ abnכmal sεl dεm.

Aw dɛn kin trit trombocytosis?

If yu nɔ gɛt ɛni sayn, yu kin jɔs nid fɔ chɛk yu ɔltɛm.

rεaktiv trombosaytosis (sεkכnd trombosaytosis) bכku tεm nכ nid tritmεnt. Bɔku tɛm, di pletlɛt lɛvɛl kin kam bak to nɔmal wans di kɔndishɔn we mek di bɔku bɔku pletlet dɛn (lɛk injuri, infɛkshɔn, ɔ riakshɔn we dɛn du ɔpreshɔn) dɔn dɔn. Bɔt if yu gɛt sɔm sayn dɛn, yu dɔktɔ go trit di rizin we mek yu gɛt dis sik.

If yu gɛt Essential Thrombocythemia (ET) ɛn yu de gɛt sɔm kayn sik, yu dɔktɔ kin tɛl yu fɔ du sɔm tritmɛnt dɛn, lɛk:

• Fɔ tek aspirin we nɔ bɔku ɛvride: Yu kin tek aspirin ɛvride fɔ mek yu blɔd nɔ klɔt. Dis smɔl doz nɔ kin mek yu bɛlɛ at ɔ blɔd. Bɔt nɔ tek aspirin ɔltɛm we yu nɔ tɔk to yu dɔktɔ.
• Fɔ tek mɛrɛsin we de mek di pletlɛt lɛvɛl go dɔŋ: Mɛrɛsin lɛk Hydroxyurea (brand nem: Droxia®, Hydrea®, Siklos®, Mylocel®) ɛn Anagrelide (brand nem: Agrilyn®) de ridyus di prodakshɔn fɔ pletlet na di bon mɛro. intafεron alfa (brand nem: Multiferon®) de mek di abnכmal pletlet dεm nכ de divayd εn mכltiply.
• Fɔ gɛt wan we fɔ pul yu pletlɛt dɛn: If yu pletlɛt dɛn so bɔku dat yu go gɛt blɔd we go mek yu layf de pan denja, yu dɔktɔ go tɛl yu fɔ du wan tin we dɛn kɔl plateletpheresis . Dis min se yu fɔ yuz mashin fɔ filta di pletlɛt dɛn we pasmak we de na yu blɔd. Bɔt pan bɔku kes dɛm we trombosaytɔsis , pletletfɛrɛsis nɔ nid fɔ de.

Impɔtant: Nɔ bigin ɔ stɔp ɛni wan pan dɛn tritmɛnt ya if yu nɔ gɛt dɔktɔ advays. Yu fɔ tɔk bɔt ɔltin wit yu dɔktɔ ɛn du am ɔnda in gayd.

Yu tink se dɛn kin mɛn trombosaytɔsis ɔltogɛda?

Essential Trombocythemia (ET) we gɛt fɔ du wit di sik.Naw, no mɛrɛsin nɔ de fɔ mek pɔsin gɛt trombocytopenia. Bɔt yu dɔktɔ kin ɛp yu fɔ kɔntrol di sik fɔ mek yu nɔ gɛt bɔku blɔd. insay di kes f כ riaktiv trombosaytosis (we kכz fכ sεkכnd kכz), di pletlet lεvεl dεm kin kam bak to nכmal wans dεn trit di כndalayn kכz.

Yu tink se dɛn kin mek dɛn nɔ gɛt trombosaytɔsis?

Bɔku tin dɛn we kin mek pɔsin gɛt trombosaytosis nɔ kin ebul fɔ avɔyd, lɛk Essential Thrombocythemia (ET) .

Yu tink se trombosaytɔsis kin mek pɔsin in layf de pan denja?

di ay pletlεt lεvεl nכ de mek yu layf de pan denja, bכt di kכmplikεshכn dεm we kin apin – lεk blɔd kכlכt כ bad bad blɔd – kin denja.

Bɔku pan di tin dɛn we kin mek pɔsin gɛt trombocytosis na fɔ shɔt tɛm nɔmɔ, ɛn i nɔ kin rili mek pɔsin gɛt siriɔs blɔd klɔt. Insay Essential Thrombocythemia (ET) , di risk kin bɛtɛ smɔl. Bɔt yu dɔktɔ go de wach yu gud gud wan, gi yu di mɛrɛsin dɛn we yu nid, ɛn du di tin dɛn we yu nid fɔ mek yu blɔd nɔ klɔt we denja. So nɔ wɔri.

Wetin na de luk fɔ pɔrsin wae gɛt trombocytosis?

Riaktiv trombosaytosis kin sɔlv we dɛn trit di ɔndalayn prɔblɛm. Pan ɔl we yu pletlɛt kɔnt kin go ɔp fɔ shɔt tɛm (ɛn sɔntɛm fɔ lɔng tɛm afta dɛn dɔn pul yu splin), sɛkɔndari trombosaytɔsis nɔ kin mek blɔd klɔt we nɔmal.

Essential Thrombocythemia (ET) , ɔ praymari trombocytosis, kin mek yu blɔd kɔmɔt bad bad wan ɔ blɔd kin klɔt. If yu tek mɛrɛsin fɔ mek yu pletlɛt nɔmal, dat kin ɛp fɔ mek dis nɔ apin. Bɔt afta bɔku ia we pɔsin dɔn gɛt dis sik, bon mɛrɔ fibrosis (ska we de na di bon mɛrɔ) kin apin. Smɔl pipul dɛn we gɛt Essential Thrombocythemia (ET) kin gɛt lukimiya bak .

Ustɛm a fɔ go to mi dɔktɔ?

Fɔ fala yu dɔktɔ in instrɔkshɔn dɛn gud gud wan bɔt aw ɔltɛm yu fɔ go fɔ mek dɛn chɛk yu na dɔktɔ ɛn if yu fɔ du blɔd tɛst fɔ chɛk yu pletlɛt dɛn.

Ustɛm a fɔ go na di Imejɛnsi Dipatmɛnt (ETU) ?

If yu si sayn dɛm fɔ strok ɔ at atak, kɔl 1990 wantɛm wantɛm ɔ go na di ɔspitul imejensi rum we de nia yu. Yu fɔ no bɔt dɛn sayn ya.

Us kwɛstyɔn dɛn a fɔ aks mi dɔktɔ?

Yu kin aks yu dɔktɔ kwɛstyɔn dɛn lɛk:

• A fɔ wɔri bɔt di bɔku bɔku pletlɛt dɛn we a gɛt?
• A go nid fɔ du mɔ tɛst fɔ chɛk mi pletlɛt lɛvɛl bak?
• Us tɛst a go nid fɔ du fɔ no wetin mek a gɛt mi Thrombocytosis?
• Us tritmɛnt dɛn yu kin advays?
• Us chenj a kin mek na mi layf fɔ mɛn dis sik?

If yu blɔd tɛst rizɔlt sho se yu pletlɛt dɛn bɔku, nɔ panik. Yu pletlɛt kin bɔku fɔ difrɛn rizin dɛn. Bɔrku pan dɛn rizin ya nɔr nid fɔ gɛt tritmɛnt. Bɔt if yu lɛvɛl de ɔp ɔltɛm ɛn yu gɛt sɔm sayn dɛn, yu dɔktɔ go tray fɔ fɛn di tin we mek yu gɛt dis sik. Fɔ tek tɛm wach ɛn tek mɛrɛsin kin ɔltɛm mek dɛn nɔ gɛt di siriɔs prɔblɛm dɛn we gɛt fɔ du wit trombosaytɔsis.

Fɔ dɔn, tin dɛn fɔ mɛmba (Take-Home Message) .

Wɛl, wi bin tɔk bɔku bɔt Thrombocytosis tide, nɔto so? A op se yu ɔndastand dis gud gud wan.

Di tin we impɔtant pas ɔl na fɔ nɔ panik if yu kam fɔ no se yu pletlɛt lɛvɛl bɔku. Nɔto ɔl di kes dɛm wae gɛt Thrombocytosis na denja.

• Riaktiv Thrombocytosis na di kayn we we kכmכn pas כl, εn i kin kכz fכ כda tεmporari kכz. Dis go bɛtɛ bak wans dɛn dɔn trit da kɔz de.
• Essential Thrombocythemia (ET) na wan kayn we we nɔ kin apin so ɔltɛm we kin nid fɔ mɛn am fɔ lɔng tɛm.
• Mek shɔ se yu du di rayt tɛst ɛn tritmɛnt dɛn lɛk aw yu dɔktɔ tɛl yu fɔ du.
• Nɔ ignore ɛni sayn we de sho se yu gɛt dis sik. Go to dɔktɔ wantɛm wantɛm, mɔ if yu gɛt blɔd we nɔ kɔmɔn, yu gɛt brus, yu ed de at bad bad wan, yu chɛst de pen, ɔ yu nɔ ebul fɔ blo.
• Tɔk opin wan wit yu dɔktɔ. Aks ɛni kwɛstyɔn ɔ tin we de mɔna yu.

Mɛmba se nɔto yu wangren de. If yu gɛt di rayt mɛdikal gayd ɛn sɔpɔt, yu kin ebul fɔ mɛn dis sik fayn fayn wan ɛn liv wɛl bɔdi layf.