Acute Fatty Liver of Pregnancy (AFLP): Dis na siriɔs tin, lɛ wi no!

Yu no se sɔntɛnde, wɛlbɔdi prɔblɛm dɛn we yu nɔ bin de ɛkspɛkt kin kam we yu gɛt bɛlɛ? Tide wi go tɔk bɔt wan sik wae kin gɛt siriɔs sik wae fayn fɔ no bɔt, ivin if na smɔl tin wae wi nɔr bin de ɛkspɛkt. Pan ɔl we dis nɔ kin apin to bɔku pipul dɛn, if i apin, i nid fɔ gɛt tritmɛnt kwik kwik wan.

wetin na dis we dεn kכl fεt liva sik (AFLP) we uman bεlε?

Fɔ tɔk am simpul wan, Acute Fatty Liver of Pregnancy (AFLP) na wan sik we nɔ kin apin so ɔltɛm bɔt we rili siriɔs. Dis na we yu liva kin ful-ɔp wit fat tumɔs we yu gɛt bɛlɛ. Dis kin mek di liva nɔ wok fayn ɛn ɔda prɔblɛm dɛn we kin mek pɔsin in layf de pan denja. Infakt, dɛn kin tek am se na mɛdikal imejensi . If dis apin, di bεst tin fכ du na fכ bכn di pikin kwik kwik wan.

Aw AFLP kɔmɔn?

Nɔ wɔri, dis nɔ kin rili kɔmɔn. Dis kɔndishɔn we dɛn kɔl AFLP na rili rare. Dɛn se i kin afɛkt wan pan ɛvri 10,000 to 20,000 bɛlɛ dɛn nɔmɔ insay wan ia. So nɔto sɔntin we yu kin si bɔku tɛm.

Wetin na di sayn dɛm fɔ AFLP? (Una fɔ no bɔt dɛn tin ya)

AFLP kin bigin insay di let tכd ​​trimεst we di bεlε de – arawnd 36 wik – εn dεn kin no am bכku tεm. Bɔt sɔntɛnde i kin apin bifo tɛm, ɔ ivin te dɛn bɔn di pikin.

Sɔm sayn dɛm de wae dɛn kin si pan dis sik:

• Nɔs ɛn vɔmit: Pan ɔl we dis kin tan lɛk se i nɔmal we uman gɛt bɛlɛ, sɔntɛnde i kin bi sayn fɔ AFLP.
• bɛlɛ pen: Dis pen kin apin mɔ na di ɔp rayt pat na di bɛlɛ.
• Taya bad bad wan: Nɔto jɔs taya, bɔt i kin fil se yu taya pasmak.
• Fɔ fil se yu nɔr de fil fayn na yu bɔdi: Na yu bɔdi nɔr de fil fayn, lɛk se yu de gɛt sik.
• Anorexia: Fɔ lɛf fɔ du ɔl wetin i want fɔ it.
• Fɔ fil se yu tɔsti bad bad wan: Ilɛk ɔmɔs wata yu drink, i stil de fil lɛk se i nɔ go du fɔ yu.
• Jandis: Yu skin ɛn di wayt pat na yu yay kin tɔn yɔlɔ. Dis na sayn we rili klia.
• Kɔnfyushɔn ɔ nɔ ebul fɔ pe atɛnshɔn: I nɔ kin izi fɔ pe atɛnshɔn, i kin fil se i nɔ gɛt rɛst.

Mɛmba se di sayn dɛm fɔ AFLP kin tan lɛk ɔda mɛrɛsin dɛm. So i impɔtant fɔ tɔk to yu dɔktɔ bɔt ɛni ɔda kayn sik we yu gɛt we yu gɛt bɛlɛ. AFLP na mɛdikal imejensi we nid fɔ gɛt tritmɛnt kwik kwik wan.

Wetin mek dis AFLP kin apin? Wetin na di rizin?

Risach pipul dɛn stil nɔ no bɛtɛ bɛtɛ wan wetin kin mek pɔsin gɛt AFLP. Wan pan di men wok we wi liva de du na fɔ brok di fat asid dɛn. insay AFLP, prכblεm de wit di liva in ebul fכ brok dεn fεt asid dεm ya, we de mek di fεt we pasmak de bכku na di liva. afta dat dis fεt de trכp insay di liva, we de ambɔg di nכmal wok we di liva de du. Dis kin mek pɔsin in layf de pan denja if dɛn nɔ trit am.

Yu tink se sɔntin de we gɛt fɔ du wit di jɛnɛtiks? (LCHAD defisiɛns)

Sɔm stɔdi dɛn dɔn sho se AFLP kin gɛt jɛnɛtik inflɔɛns . Dat min se i kin bi bikɔs ɔf wan ɛnzaym we nɔ de wok we dɛn kɔl lɔng chen 3-haydroksiasil-CoA dɛhaydrojɛnɛz (LCHAD) dɛfisiɛns .

Dis (LCHAD) dɛfisiɛns na wan sik we nɔ kin apin so ɔltɛm, (ɔtosomal rɛsɛsiv) disɔda . Fɔ tɔk am simpul wan, fɔ mek pikin gɛt dis, in mama ɛn papa ɔl tu fɔ gɛt di jin we gɛt fɔ du wit am. di pikin we gεt (LCHAD) dεfisiεns nכ kin mεtabolayz fεt asid dεm fayn fayn wan. afta dat dεn fεt asid dεm ya de go insay di mama in bכdi tru di plasεnta. Dis kin mek di fat gɛda na di mama in liva. Imajin aw we di pikin in bɔdi chenj, dat kin afɛkt di mama!

Wetin na di risk factor dɛm fɔ mek yu gɛt AFLP?

Wi no naw se dis kכndyushכn, we dεn kכl AFLP, kin bi jεnεtik. Dat min se dɛn kin gɛt am frɔm mama ɛn papa. Apat frɔm dat, sɔm ɔda tin dɛn de we kin mek pɔsin gɛt dis sik:

• If dis na yu fɔs bɛlɛ.
• If yu de ɛkspɛkt twins ɔ mɔ.
• If yu de expekt bɔbɔ.
• If yu gɛt dayabitis.
• If yu gɛt intrahepatic cholestasis fɔ bɛlɛ.
• If yu gɛt prɛeklampsia.
• If yu fat pasmak.

Bɔt, ivin wit ɔl dɛn risk factor ya, yu dɔktɔ nɔ kin ebul fɔ tɔk if yu go gɛt AFLP. Ɛn i nɔto sɔntin we yu go ebul fɔ tɔk wetin go apin ɛn mek yu nɔ ebul fɔ du am. Na dat mek i de wɔri smɔl mɔ.

Wetin na di prɔblɛm dɛn we kin apin we AFLP kin apin? (Dis kin bi denja)

Akyu fat liva sik (AFLP) we uman gɛt bɛlɛ kin kil pɔsin . Yu ɛn yu pikin de pan denja fɔ gɛt difrɛn prɔblɛm dɛn. Sɔm pan dɛn na:

• Liva nɔ de wok fayn.
• Kidni we nɔ de wok fayn.
• Lɔng we nɔ de wok fayn.
• Sik we de prɛd.
• Ɛmoraji we de kɔmɔt na di bɔdi.

I kin mek pɔsin fred fɔ yɛri dɛn tin ya, nɔto so? Na dat mek i impɔtant fɔ no bɔt dis tin we de apin.

Aw fɔ no di AFLP stetɔs?

Bikɔs AFLP kin mek di ɔgan dɛn nɔ wok fayn, .I impɔtant fɔ no di sik kwik kwik wan ɛn bigin fɔ trit am kwik. Di kɔrɛkt we aw dɛn kin no di sik na we dɛn tek di liva bayɔpsi . Dis na di say we yu dɔktɔ de chɛk yu liva tisu ɔnda maykroskɔp. Bɔt nɔto ɔltɛm dis kin fayn fɔ du we uman gɛt bɛlɛ. So, bɔku tɛm yu dɔktɔ kin no if yu gɛt AFLP bay di sayn dɛm ɛn yu wɛlbɔdi istri.

Wetin blɔd tɛst kin luk fɔ?

Yu dɔktɔ go ɔda fɔ mek dɛn du blɔd tɛst fɔ chɛk fɔ AFLP. Sɔntɛnde yu dɔktɔ kin sɔprayz se AFLP de bay di rizɔlt dɛn we di liva de du blɔd tɛst . Bɔku tɛm, dɛn tɛst ya kin sho tin dɛn lɛk:

• di εnzym dεm na di liva we de εlevεt.
• Prɔblɛm dɛn we de wit di we aw yu blɔd de klɔt.
• di lεvεl dεm we di amonia, yurik asid, εn protin de insay di bכdi de go כp.
• Di shuga we de na di blɔd we nɔ bɔku.
• Sayn dɛn we de sho se di kidni dɔn pwɛl.

Ɔda tɛst dɛn

Fɔ mek dɛn no se yu gɛt di sik, yu dɔktɔ kin ɔda fɔ mek dɛn tek ɔltra saund ɔ CT skan . Dɛn tin ya kin gi ditayli pikchɔ dɛn bɔt di liva.

Aw dɛn kin trit AFLP? (I impɔtant fɔ trit kwik kwik wan!)

Fɔ mek yu nɔ gɛt prɔblɛm dɛn we go mek yu day, yu dɔktɔ go tɛl yu fɔ bɔn yu pikin kwik kwik wan . Afta dεn dכn pul di pikin εn di plasεnta, yu liva go bigin fכ bכn sכmtεm. Dis na di men ɛn di wangren tritmɛnt fɔ dis sik.

Ɛnitin de we a kin du fɔ ridyus mi risk fɔ gɛt AFLP?

Dis na prɔblɛm we bɔku pipul dɛn gɛt. AFLP na wan sik we nɔ kin apin so ɔltɛm. Ɛn, natin nɔ de we yu go du fɔ mek i nɔ apin ɔ fɔ no am bifo tɛm . Dis na di ɔnaful pat pan dis sik.

Wetin kin apin if a gɛt AFLP?

If yu gɛt AFLP, yu fɔ bɔn yu pikin wantɛm wantɛm . yu liva fכnshכn go bigin fכ kam bak to nכmal insay lεk 10 dez afta yu bכn. Yu go nid fɔ mek di ɔspitul in dɔktɔ dɛn de wach yu te yu liva tɛst rizɔlt kam bak to nɔmal.

I nɔr pɔsibul fɔ tɔk ɛksaktɔli wetin na yu risk fɔ gɛt AFLP bak. Yu dɔktɔ kin tɛl yu fɔ du di jenɛtik tɛst fɔ si if ɛnitin de we nɔ fayn na di fat asid dɛn we go dɔn mek AFLP bigin. Dɛn kin advays bak se if yu gɛt bɛlɛ bak tumara bambay, yu fɔ mek wan spɛshal dɔktɔ we de mɛn di mama ɛn pikin we de na di bɛlɛ fɔ wach yu bɛlɛ .

Wetin bad wit di pikin?

di kayn sik we di mama kin gɛt kin sho aw i kin afɛkt di pikin. sכm pikin dεm de pan risk fכ gεt wan kכndyushכn we dεn kכl nonketotic hypoglycemia (we dεn nכ ebul fכ proses di amino asid dεm fayn fayn wan). Ɔda wan dɛn kin gɛt tin dɛn lɛk dilated cardiomyopathy (wan at mɔsul we wik) ɔ nyuropathy (nɛv we dɔn pwɛl). Bɔt bɔku tɛm, di prɔblɛm we kin apin to di pikin kin smɔl pas di prɔblɛm we kin apin to di mama.

Ustɛm a fɔ go to di dɔktɔ?

I impɔtant fɔ sheb yu kɔmplit mɛdikal histri wit yu dɔktɔ we yu gɛt bɛlɛ ɛn fɔ mek dɛn no bɔt ɛni sayn we yu de gɛt. If yu ɔnɛs, dat go ɛp yu fɔ gɛt di bɛst mɛrɛsin we yu nid.

If yu gɛt ɛni wan pan dɛn tin ya we yu gɛt bɛlɛ, go to dɔktɔ wantɛm wantɛm :

• Abdominal ɔ pelvik pen we nɔ de go.
• Taya pasmak ɔ we yu nɔ de fil fayn.
• Nɔs ɛn vɔmit we de kɔntinyu fɔ de.
• Wan ed pen we nɔ go dɔn.

Dis kin bi nɔmal bɛlɛ simptom dɛm, bɔt dɛn kin bi sayn bak fɔ sɔmtin we siriɔs. So nɔ dawt.

Us kwɛstyɔn dɛn a fɔ aks mi dɔktɔ?

Imajin, if yu dɔktɔ tɛl yu se yu gɛt AFLP... na nɔmal tin fɔ mek yu gɛt bɔku kwɛstyɔn. Yu kin aks yusɛf kwɛstyɔn dɛn lɛk:

• "Dɔkta, a fɔ deliv di pikin naw?"
• "Mi layf de pan denja?"
• "Mi pikin in layf de pan denja?"
• "Dis AFLP situeshɔn go bɛtɛ?"
• "Us kayn tritmɛnt a nid?"
• "Dis go hapun bak if a get bele bak?"
• "Wetin mek dis apin to mi, dɔktɔ?"

Aks ɛni kwɛstyɔn we yu kin tink bɔt lɛk dis. Nɔ ol ɛnitin bak.

Wetin na di difrɛns bitwin AFLP ɛn HELLP sindrom?

HELLP sεndrכm ( Hemolysis, Elevated Liver Enzymes, and Low Platelet Count Syndrome)** na wan kכndyushכn we de apin we uman bεlε εn i sכm kayn we lεk AFLP. Di men difrɛns bitwin di tu kɔndishɔn na aw di blɔd tɛst rizɔlt kin chenj as tɛm de go. AFLP kin involv prɔblɛm wit di blɔd we de klɔt ɛn chenj na di pletlɛt lɛvɛl. Bɔt di HELLP sindrom kin gɛt fɔ du wit we di pletlɛt dɛn kin go dɔŋ smɔl smɔl.

Apat frɔm dat, pipul dɛm wae gɛt AFLP kin gɛt dis sik:

• Sivεr abnכmaliti dεm na di liva fכnshכn tεst dεm.
• Ɛnitin we nɔ fayn na di blɔd shuga lɛvɛl.
• Sayn dεm fכ abnכmaliti na di kidni fכnshכn.
• di ay bilirubin lεvεl (bilirubin na west prodakt) insay tεst.
• Acidosis (we de mek di blɔd gɛt mɔ asid).
• (Protɛinuria) .(Prεsεns fכ protin na di urine).
• di chenj dεm we de apin na di bren fכ wok (e.g., we yu nכ ebul fכ tink klia wan, kכnfyushכn).

Yu tink se i nɔmal fɔ gɛt fat liva we yu gɛt bɛlɛ?

Ivin pan pipul dɛm wae nɔr gɛt bɛlɛ, fat liva sik na kɔmɔn sik wae dɛn kin trit. Bɔku pipul dɛn kin gɛt sɔm fat na dɛn liva. Bɔt if dis fat bɔku, i kin mek di liva nɔ wok. Dis kin denja mɔ we uman gɛt bɛlɛ , bikɔs yu liva na di we aw di bɔdi de pul di pɔyzin dɛn. If yu liva (ɔ yu pikin in liva) nɔ de wok fayn, tin dɛn we de ambɔg yu kin gɛda na yu blɔd.

Fɔ dɔn, dis na wetin a gɛt fɔ tɛl una (Take-Home Message)

AFLP, ɔ akyu fat liva sik we uman gɛt bɛlɛ, na sik we nɔ kin apin so ɔltɛm bɔt we kin rili siriɔs. Dɛn nɔ go ebul fɔ stɔp am ɔ tɔk bɔt am. Dis min se i impɔtant fɔ tɔk to yu dɔktɔ bɔt yu wɛlbɔdi istri ɛn ɛni ɔda kayn sik we yu go gɛt we yu gɛt bɛlɛ. Dɛn tɔk ya go ɛp yu dɔktɔ fɔ no di prɔblɛm dɛn we kin apin ɛn gi yu di mɛrɛsin we yu nid.

Nɔ fred, bɔt tek tɛm . Pe atɛnshɔn to yu bɔdi. If yu fil ɛnitin we nɔ kɔmɔn ɔ we difrɛn, go to dɔktɔ wantɛm wantɛm. Di tin we impɔtant pas ɔl na fɔ mek yu ɛn yu pikin gɛt wɛlbɔdi.

` Fεt liva we uman bεlε, AFLP, bεlε komplikashכn, liva sik, janda, dεlivεri, LCHAD dεfisiεns