Lɛ wi lan bɔt Aldosterone, we kin afɛkt yu blɔd prɛshɔn sikrit wan.

Wan prɔblɛm we bɔku pipul dɛn na Sri Lanka gɛt na ay blɔd prɛshɔn. Fɔ sɔm, i kin rili at fɔ kɔntrol dis ivin afta dɛn dɔn tek mɛrɛsin. Bɔt sɔmbɔdi de insay wi bɔdi we wi nɔ kin tɔk bɔt bɔku, bɔt sikrit wan kin afɛkt di blɔd prɛshɔn. Na dat wi go tɔk bɔt tide. In nem na Aldosterone.

Fɔ tɔk am simpul wan, udat na dis aldosterone?

Aldosterone na wan ɔmon we de na wi bɔdi. Ɔmon dɛn tan lɛk di postman dɛn na wi bɔdi. Dɛn kin kɛr mɛsej to ɛni ɔgan, de tɛl am fɔ du dis, stɔp dat.

So dis ɔmon we dɛn kɔl aldosterone na tu smɔl triangul gland dɛn we tan lɛk kap we de ɔp wi kidni dɛn de mek am. Wi kin kɔl dɛn tin ya di adrenal gland dɛn. dis gland dεm na pat pan wi εndokrin sistεm.

Di men wok we dis ɔmon de du na fɔ mek wi blɔd prɛshɔn de di rayt lɛvul . i de du dis bay we i de kכntro di lεvεl dεm fכ di minral dεm na wi bכdi we dεn kכl sכdiכm (dat na sכl) εn potashכm. Dɛn sɔdiɔm ɛn potashɔm ya na tu kayn ilɛktrɔlayt dɛn . Na dεn wan dεm we de mek di bכdi in wata bεlε εn εp di nerv dεm εn mכsul dεm fכ wok fayn fayn wan.

Aw aldosterone kin kɔntrol blɔd prɛshɔn?

Dis na wan prɔses we rili intrestin. Aldosterone kin afɛkt di blɔd prɛshɔn mɔ pan dɛn we ya:

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2. Wata we de kip wata: We dɛn ad sɔdiɔm to di blɔd, wata de kip bak na di bɔdi. I tan lɛk se wata atrak sɔl.

3. Blɔd volyum we de go ɔp: We wi kip wata na wi bɔdi, wi ɔl blɔd volyum de go ɔp. Jɔs lɛk aw if yu ful-ɔp wata paip wit mɔ wata, dat kin mek in prɛshɔn go ɔp, we blɔd volyum go ɔp, blɔd prɛshɔn bak kin go ɔp.

Dis we ya, we wi blɔd prɛshɔn go dɔŋ, aldosterone de step insay ɛn ɛp fɔ mek i kam bak to wɛlbɔdi lɛvɛl. dis כmon de εp bak indaykt wan fכ rεgεl di pH (i.e., asid-bεys bεlε) εn εlektrolayt lεvεl dεm na di bכdi.

Aw dɛn kin kɔntrol dɛn aldosterone lɛvɛl ya? - Wan wɔndaful prɔses!

Aldosterone nɔ de wok in wan. Na pat pan wan tim we de wok togɛda. Wi kin kɔl dis sistɛm di Renin-Angiotensin-Aldosterone System (RAAS) . I tan lɛk se na rilay res.

Tink bɔt am dis we.

• Fɔs tin we yu fɔ du: Yu blɔd prɛshɔn (BP) de go dɔŋ. Wi kidni dɛn kin no dis. Dɔn di kidni dɛn kin pul wan ɛnzaym we dɛn kɔl renin insay di blɔd.
• Step tu: Dis renin de go ɛn brok wan protin we dɛn kɔl angiotensinogen, we wi liva de mek, to wan pat we dɛn kɔl angiotensin I. Bɔt i stil de slip, we min se i nɔ gɛt bɔku pawa.
• Step Tri: Naw, as dis angiotensin I de travul tru di blɔd, di angiotensin-converting enzyme (ACE) we de kɔmɔt na wi lɔng dɛn de brok am, ɛn dis de mek wan ɔmon we rili pawaful we dɛn kɔl angiotensin II . Dis na di rial hiro.
• Step Fo: Dis angiotensin II de du tu men tin.

1. I de mek di smɔl smɔl blɔd vesel dɛn (arterioles) kɔnstrikt. Dis kin mek di blɔd prɛshɔn go ɔp wantɛm wantɛm.

2. I de go na di adrenal gland dεm εn tεl dεm se, "Imergency! Kwik kwik wan prodyuz aldosterone!"

• di las step: Naw aldosterone de kam insay εn tεl di kidni dεm fכ kip sכl (sכdiכm) εn wata εn kכmכt sכm potashכm. Dis kin mek di blɔd bɔku ɛn mek di blɔd prɛshɔn kam bak to nɔmal.

We dis ɔltin dɔn dɔn, ɛn blɔd prɛshɔn dɔn kam bak to nɔmal, dis sistɛm kin stɔp fɔ wok. Dis na wan kɔntrol sistɛm we rili kɔmpleks, bɔt we rili wɔndaful.

Aw dɛn kin mɛzhɔ di aldosterone lɛvɛl?

If yu dɔktɔ gɛt prɔblɛm fɔ kɔntrol yu blɔd prɛshɔn, ɔ if yu gɛt chenj na yu blɔd potashɔm lɛvɛl, i kin sɔprayz se i gɛt aldosterone. di men tεst fכ dis na di aldosterone:renin ratio test .

Bikɔs aldosterone ɛn renin de wok togɛda, if yu mɛzhɔ di lɛvɛl dɛn we dɛn ɔl tu gɛt, dat kin ɛp fɔ no usay di prɔblɛm de. Bɔku tɛm, dɛn kin du dis bay we dɛn tek smɔl blɔd frɔm wan vein we de na yu an.

pan tap dat, dεn kin mכsu di aldosterone lεvεl sεparat wan insay bכdi כ urine we dεn kכlekt ova 24 awa.

Wetin kin apin if di aldosterone lɛvɛl go ɔp?

we di lεvεl fכ aldostεron na di bכdi hכy pas nכmal, wi kin kכl am hyperaldosteronism . di men tin we kin mek dis apin na wan kכndyushכn we dεn kכl praymar aldosteronism . DisDɛn kin kɔl am bak di sik we dɛn kɔl Conn’s syndrome.

dis kכndyushכn kin kכz fכ wan sכmכl, nכn kεnsar (benign) tכmכro we de divεlכp na wan adrenal gland. dis tכmכro de mek di gland prodyuz tu mכch aldosterone. Dis kin mek di sodium (sɔl) na di blɔd go ɔp, di potashɔm kin go dɔŋ, ɛn di ilɛktrɔlayt nɔ balans.

Wetin kin apin if di aldosterone lɛvɛl go dɔŋ?

Dɔn bak, we di lɛvɛl we di aldosteron de na di bɔdi smɔl pas aw i kin bi, wi kin kɔl am haypoaldosteronism . dis na we di aldosterone homon de prodyuz sכmtεm כ in wok nכ de wok fayn. dis kin mek di sodium (sכlt) na di bכdi dכn, di potashכm go bכku, εn wan kכndyushכn we dεn kכl mεtabolik asidכsis ( di asid we de bכku na di bכdi).

Wetin na di rizin dɛn we mek dɛn de du dis?

• Di sik we Addison gɛt:Dis na wan sik we nɔ kin apin ɔltɛm we di ɔtoimyun sik kin kam. dis min se di bכdi in yon difεns sistεm de tכn agens insεf εn i de pwεl di adrenal gland dεm. dis de ridyus di prodakshכn fכ כl tu di כmon dεm we dεn kכl aldosterone εn kכtisol.
• Congenital Adrenal Hyperplasia (CAH): Dis na wan jεnεtik kכndyushכn we de de we dεn bכn am. I kin mek sɔm ɛnzaym dɛn we dɛn nid fɔ mek ɔmon dɛn na di adrenal gland dɛn nɔ de.
• Ɔda sik dɛn we pɔsin kin gɛt: Dis sik kin apin to pipul dɛn we gɛt dayabitis, kidni sik, ɛn di wan dɛn we sik bad bad wan.
• Sɔm mɛrɛsin dɛm: Dis sik kin kam bak bikɔs ɔf mɛrɛsin dɛm wae de mek pɔrsin fil pen (NSAID) , mɛrɛsin wae de mek yu blɔd tan lɛk ɛparin, ɛn sɔm mɛrɛsin dɛm wae de gi yu at.

If yu gɛt dɛn sik ya, i rili impɔtant fɔ mek apɔntinmɛnt fɔ go to yu dɔktɔ ɛn tɔk bɔt dis.