Sɔntɛm dɔktɔ dɔn tɔk to in fambul ɔ padi bɔt ‘stem sɛl transplant’. Ɔ sɔntɛm dɛn dɔn tɛl yu dis tritmɛnt fɔ wan sik lɛk lukimiya. I rili nɔmal fɔ fil smɔl fred ɛn fred we yu yɛri dis nem. Bɔt dis na tritmɛnt we rili impɔtant we kin sev bɔku pipul dɛn layf. So tide, lɛ wi tɔk rili simpul ɛn klia wan bɔt wetin na dis ‘Allogeneic Stem Cell Transplant’, aw dɛn kin du am, ɛn wetin na di risk dɛm.
Fɔ tɔk am simpul wan, wetin na allogeneic stem cell transplant?
Dis rili izi fɔ ɔndastand. allojenik stεm sεl transplant na we dεn pul yu כwn stεm sεl dεm we sik εn riples wit stεm sεl dεm frכm hεlty, kכmpatibl dכna. dis stεm sεl dεm na spεshal kayn sεl we de insay wi bon mכro we kin divεlכp to eni kayn bכdi sεl (rεd bכdi sεl, wayt blכd sεl, pletlet).
We dɛn wɛlbɔdi sɛl dɛn ya we dɛn dɔn gi go insay yu bɔdi, dɛn kin travul go na yu bon mɛrɔ ɛn bigin fɔ mek nyu wɛlbɔdi blɔd sɛl dɛn. Dis na pawaful tritmɛnt we kin ivin mɛn sɔm siriɔs sik dɛn kpatakpata. Dɔktɔ dɛn kin yuz dis tritmɛnt we ɔda tritmɛnt dɛn nɔ wok ɔ we di sik dɔn kam bak.
Us kɔndishɔn dɛn kin yuz dis tritmɛnt fɔ?
Allogeneic stem cell transplantation na in dɛn kin yuz mɔ fɔ sik dɛn we gɛt fɔ du wit di blɔd ɛn di imyun sistɛm.
| Men kɔndishɔn dɛn we dɛn dɔn trit |
|---|
| Akyu Limfoblastik Lukimiya (ALL) . |
| Akyu Maylɔyd Lukimiya (AML) . |
| Aplastic Anemia - Bɔn mɛrɔ we nɔ de wok fayn |
| Limfoma - kansa na di limf no dɛm |
| Maylodisplastik Sindrom we dɛn kɔl di sik |
| Mayloproliferativ Nioplasms (MPN) . |
| Siklɔs Sɛl Sik |
Aw yu kin pripia bifo yu gɛt tritmɛnt?
Bikɔs dis na big tritmɛnt, dɔktɔ dɛn go du bɔku tɛst fɔ chɛk yu bɔdi fayn fayn wan bifo dɛn du di tritmɛnt fɔ mek shɔ se yu ebul fɔ bia wit di sayd ɛfɛkt dɛn we di tritmɛnt gɛt.
Men tɛst dɛn we dɛn bin du
Yu mɛdikal tim go du bɔku tɛst dɛn, lɛk:
- Kɔmplit Blɔd Kɔnt (CBC): I de chɛk yu rɛd blɔd sɛl, wayt blɔd sɛl, ɛn pletlɛt lɛvɛl.
- Echocardiogram: Si aw di at de wok fayn fayn wan.
- Ilɛktrokardiogram (EKG): I de chɛk aw di at de wok.
- Test fɔ di liva ɛn kidni fɔ wok.
- Bone Marrow Biopsy: If yu gɛt kansa, dɛn kin tek smɔl sampul pan yu bon marrow ɛn tɛst am. Dis kin ɛp fɔ no di chenj dɛn we de apin na di sik ɛn di risk fɔ mek di sik kam bak afta dɛn dɔn trit am.
Kɔndishɔn bifo dɛn transplant am
Afta dɛn tɛst ya, dɛn go admit yu na ɔspitul ɛn gi yu tritmɛnt we dɛn kɔl ‘kɔndishɔn’. Dis involv fɔ yuz strɔng kemotɛrapi ɛn/ɔ ɔl bɔdi redyushɔn tɛrapi . Dis gɛt tri gol dɛn:
1. Fɔ pwɛl ɛni kansa sɛl we lɛf na yu bɔdi.
2. Mek rum na yu bon mכro fכ nyu stεm sεl dεm fכ gro.
3. Fɔ mek yu imyun sistɛm wik. dis de ridyus yu bכdi in ebul fכ atak (rijek) nyu sεl dεm.
Dis kondishɔn prɔses kin tek wan ɔ tu wik.
Wetin kin apin we dɛn de transplant stem sɛl?
Dis nɔ kin rili mek pɔsin fil pen. Yu mɛdikal tim go put wan smɔl tiub we dɛn kɔl sɛntral venɔs kateta (CVC) insay wan big vein na yu ɔpa chɛst. di nyu stεm sεl dεm go gi yu bכdi tru dis tכb.
Na simpul tin we pɔsin kin du, jɔs lɛk fɔ gi blɔd. di hεlty stεm sεl dεm we de insay salin bag dεn de infuz insay yu bכdi tru wan CVC tyub. Frɔm de, dɛn kin travul go na yu bon mɛro.
Dis prɔses kin tek lɛk 30 to 60 minit. Insay dis tɛm, di mɛdikal tim go sidɔm nia yu ɛn wach yu impɔtant sayn dɛn. Dɛn go wach gud gud wan bak fɔ ɛni sayd ɛfɛkt. Di sayd ɛfɛkt dɛn nɔ kin bɔku ɛn bɔku tɛm dɛn kin smɔl. Fɔ ɛgzampul, yu kin shek smɔl, i nɔ kin izi fɔ yu fɔ blo, ɔ yu kin gɛt fiva.
Wetin na di men prɔblɛm we dis tritmɛnt kin gɛt?
di mכst siriכs εn siriכs komplikεshכn fכ allojεnik transplant na graft-vεrs-hכst sik (GVHD) .
fכ simpul wan, dis na we di nyu hεlty imyun sεl dεm frכm di dכna (di graft) de bigin fכ atak di hεlty sεl dεm εn tisu dεm na yu bכdi (di hos). I tan lɛk se nyu ami de atak di pipul dɛn na yu yon kɔntri. Dis sik kin afɛkt di skin, di liva, ɛn di dijestiv sistɛm. Bɔt yu nɔr nid fɔ wɔri, dɔktɔ kin gi yu di mɛrɛsin wae yu nid fɔ kɔntrol ɛn trit dis sik.
Wetin kin apin afta dɛn dɔn trit am? Aw lɔng i kin tek fɔ mek i wɛl?
Afta di transplant, yu go nid fɔ de na ɔspitul fɔ sɔm wiks. Insay da tɛm de, di mɛdikal tim go tek kia ɔf yu gud gud wan. Yu go kɔntinyu fɔ gɛt di imyunosuppressant fɔ mek yu bɔdi nɔ rijek di nyu sɛl dɛn we dɛn dɔn transplant. Yu kin nid bak fɔ tek blɔd te di nyu sɛl dɛn ebul fɔ mek nyu blɔd sɛl dɛn.
di prכsεs we di nyu sεl dεm de go insay di bon mכro εn bigin fכ mek nyu bכdi sεl dεm dεn kכl am ‘engraftment’ . Dis kin tek lɛk 10 to 14 dez. Bɔt i kin tek sɔm mɔnt to wan ia ɔ mɔ fɔ mek yu imyun sistɛm kam bak fayn fayn wan. Insay dis tɛm, i rili impɔtant fɔ protɛkt yusɛf frɔm infɛkshɔn.
I kin tek tu ia ɔ mɔ fɔ mek yu wɛl ɔl, so dis na waka we yu nid fɔ peshɛnt ɛn fala wetin yu dɔktɔ tɛl yu fɔ du.
Wetin na di sayn dɛm wae kin mek yu go to dɔktɔ kwik kwik wan?
We yu go na os afta yu dɔn gɛt tritmɛnt, yu fɔ pe atɛnshɔn to yu bɔdi gud gud wan. If yu gɛt ɛni wan pan dɛn sik ya, kɔl yu mɛdikal tim wantɛm wantɛm .
| Kategori fɔ di simptom dɛn | Ficha dɛn we yu fɔ luk fɔ |
|---|---|
| I kin bi sayn dɛm fɔ graft-versus-host disease (GVHD) . | |
| Dijestiv sistɛm | Bɛlɛ de at, dayarɛa, nɔs, ɛn vɔmit. |
| Skin ɛn yay | I de it ɛn pul di skin, di skin ɛn/ɔ di yay de yɔlɔ (jaundice). |
| I kin bi sayn fɔ se yu gɛt di sik | |
| Jɛnɛral kwaliti dɛn | Fiva we pas 38 Sɛlshiɔs (100.4 Fɛnayt) ɔ pas dat, kol, kɔf, snis, nɔs we de rɔn . |
| Ɔda tin dɛn we de apin | Diziz , i nɔ kin izi fɔ blo, i kin pis ɔltɛm, ɔ i kin bɔn we i de pis. |
Wetin na di difrɛns bitwin allogeneic ɛn autologous transplant?
di men difrεns bitwin di tu na di say we di stεm sεl dεm de kכmכt.
allogeneic transplant: dεn kin gεt stεm sεl dεm frכm כda pכsin (wan dכna).
Autologous transplant: Dɛn kin tek di stem sɛl dɛn frɔm yu (dɛn kin tek yu yon sɛl dɛn bifo dɛn gi yu strɔng kemotɛrapi, dɔn dɛn kin put dɛn bak insay yu bɔdi).
Allogeneic transplant kin mɛn sɔm sik dɛn we kin mek pɔsin in layf de pan denja. Bɔku tɛm, dis kin apin bikɔs strenja dɛn kin du gud to dɛn. Dis na di pipul dɛm we de gi stem sɛl. Sɔntɛnde, di wan dɛn we de gi mɔni na famili mɛmba dɛn. Risk dɛn de we pɔsin kin gɛt we i gɛt sɛl dɛn we dɛn dɔn gi. Tek tɛm ɔndastand di bɛnifit ɛn risk dɛn we dis we aw dɛn kin du tin kin gɛt. Yu dɔktɔ kin ɛp yu fɔ no di prɔblɛm dɛn ɛn di bɛnifit dɛn we yu go gɛt so dat yu go fil se yu gɛt kɔnfidɛns pan wetin yu dɔn disayd.
Mɛsej we dɛn kin kɛr go na os
- Allogeneic stem cell transplant na we fɔ yuz wɛl bɔdi sɛl frɔm ɔda pɔsin fɔ trit siriɔs blɔd sik lɛk lukimia.
- Bifo dɛn trit am, dɛn kin pripia di bɔdi bay strɔng tritmɛnt dɛn lɛk kemotɛrapi.
- Risk de fɔ mek di pɔsin in sɛl dɛn atak di pɔsin in bɔdi (graft-versus-host disease), bɔt dɔktɔ dɛn kin rili tek tɛm wit dis.
- I kin tek lɔng tɛm fɔ mek i wɛl gud gud wan, ɛn i impɔtant fɔ fala di dɔktɔ dɛn advays ɛn fɔ chɛk-ap ɔltɛm insay dis tɛm.
- Tɔk to yu dɔktɔ opin wan bɔt ɛni kwɛstyɔn, fred, ɔ tin we de mɔna yu. Dat na di bɛst ples fɔ gɛt di kɔrɛkt infɔmeshɔn ɛn rilif.
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