Imajin aw i go mek yu fred if yu gɛt at atak ɔ strok wantɛm wantɛm. Di big prɔblɛm we kin apin dɛn kayn tɛm ya na di denja blɔd we kin kam insay di blɔd vesel dɛn na wi bɔdi. If dis blɔd klɔt stɔp na vein we de kɛr blɔd go na di at ɔ di bren, i kin mek bad bad tin pwɛl. Na dis kayn impɔtant tɛm na layf, wi de tɔk bɔt wan rili pawaful, spɛshal mɛrɛsin we go sɔlv dɛn blɔd klɔt dɛn de ɛn sev layf.
Wetin na Alteplase?
Fɔ tɔk am simpul wan, Alteplase na drɔg we dɛn kin injɛkt insay wan vein ɛn dɛn kin yuz am nɔmɔ we i gɛt ɛnitin fɔ du wit am. Di men wok we i de du na fɔ sɔlv di blɔd we dɔn fɔm na say dɛn we denja na di bɔdi. Na dat mek sɔm tɛm dɛn kin kɔl am "klɔt bɔsta".
We at atak apin, di blɔd vesel dɛn we de gi blɔd to di at kin blok bikɔs blɔd kin klɔt. Semweso, we pɔsin strok , bɔku tɛm blɔd we de klɔt kin blok wan blɔd vesel we de gi blɔd to di bren. If dis blɔd klɔt dɔn sɔlv kwik kwik wan bay we dɛn gi di mɛrɛsin we dɛn kɔl Alteplase, i kin mek di at ɔ in bren nɔ pwɛl, i kin mek di pɔsin ebul fɔ wɛl, ɛn i kin mek i nɔ gɛt disabled igen.
Di impɔtant tin na dat, dis nɔto mɛrɛsin we yu kin bay na famasi ɛn kip na os. Dɛn kin jɔs gi am na ɔspitul, ɔnda di dairekt sɔpɔtishɔn fɔ dɔktɔ ɛn nɔs wokman dɛn.
Tin dɛm wae yu fɔ tɛl yu dɔktɔ bifo yu gi dis mɛrɛsin
Bikɔs Alteplase na wan mɛrɛsin we rili pawaful, i impɔtant fɔ mek yu dɔktɔ no yu kɔmplit mɛdikal istri bifo i gi yu am. Dis na bikɔs i kin denja fɔ gi dis mɛrɛsin to pɔsin we gɛt sɔm kayn mɛrɛsin. If yu gɛt ɛni wan pan dɛn tin ya, yu fɔ rili tɛl yu dɔktɔ.
| Yu wɛlbɔdi kɔndishɔn | Wetin mek i impɔtant fɔ notis pɔsin? |
|---|---|
| We di wɔl na di blɔd vesel wik (Aneurysm) . | Risk de fɔ mek di vein we wik bikɔs ɔf di akshɔn we di mɛrɛsin de du. |
| Blɔd disɔda ɔ blɔd klɔt prɔblɛm | Dis mɛrɛsin kin mek di blɔd kɔmɔt mɔ ɛn mɔ. |
| Ɔpreshɔn ɔ bayɔpsi we dɛn jɔs du | Di wund dɛn we dɛn du ɔpreshɔn pan kin blɔd pasmak. |
| Di ay blɔd prɛshɔn we dɛn nɔ kin kɔntrol | Siriɔs tin dɛn lɛk we yu bren de blɔd kin apin. |
| Wan ed injury, bren tumor, ɔr strok bifo | Di risk fɔ mek blɔd kɔmɔt insay di skel rili bɔku. |
| Ay damej we pɔsin kin gɛt we i gɛt dayabitis (Diabetic Retinopathy) . | Blɔd kin kɔmɔt na di yay. |
| Fɔ gɛt bɛlɛ, fɔ tray fɔ gɛt bɛlɛ, ɔ fɔ gi pikin in bɛlɛ | Di dɔktɔ fɔ disayd bɔt di prɔblɛm dɛn we kin apin to di mama ɛn di pikin. |
| Alɛji to ɛni ɔda mɛrɛsin ɔ it | Fɔ mek yu nɔ gɛt alɛji fɔ di mɛrɛsin. |
Aw fɔ yuz dis mɛrɛsin ɛn wetin fɔ tek tɛm wit
Dɛn kin gi dis mɛrɛsin as injɛkshɔn tru wan kanula we dɛn put insay wan vein. Dɛn kin du dis ɔl na ɔspitul ɔ klinik.
We yu de tek di mɛrɛsin
We dɛn gi yu Alteplase, dɔktɔ ɛn nɔs dɛn go de wach yu sik gud gud wan . Dɛn go de chɛk yu at rit, blɔd prɛshɔn, ɛn ɔda impɔtant sayn dɛn ɔltɛm. Dɛn go advays yu fɔ rɛst na bed fɔ mek yu nɔ gɛt bɔku blɔd.
Risk fɔ mek yu blɔd kɔmɔt
Di men ɛn siriɔs risk fɔ dis mɛrɛsin na fɔ blɔd. Alteplase de wok bay we i de sɔlv di blɔd we de klɔt ɛn wik di bɔdi in natura l blɔd klɔt prɔses fɔ sɔm tɛm.
- So , we yu de brus yu tit ɛn klin yu nos, yu fɔ du am saful saful ɛn tek tɛm du am.
- Ivin smɔl wund na di bɔdi kin mek yu blɔd bɔku pas aw i kin blɔd.
- Nɔ ɛva tek ɔda mɛrɛsin dɛn we de mek pɔsin fil pen (especially NSAID) lɛk Aspirin ɛn Ibuprofen , ɛn ɔda tin dɛn we de mek yu blɔd tan lɛk Warfarin ɛn Heparin if yu dɔktɔ nɔ gri fɔ tek am.
Wetin fɔ du if di doz fɔ di mɛrɛsin go ɔp?
Bikɔs dɛn kin gi dis mɛrɛsin na ɔspitul, yu nɔ nid fɔ wɔri bɔt di doz. Na di wan dɛn we sabi bɔt mɛrɛsin kin kɔl am kɔrɛkt wan ɛn gi am. If dɛn tink se dɛn dɔn tek di mɛrɛsin pasmak, di wan dɛn we de wok na di ɔspitul go tɛl di ɔspitul in Imejɛnsi Tritmɛnt Yunit (ETU) wantɛm wantɛm ɔ, if nid de , di Nashɔnal Pɔyzin Infɔmeshɔn Sɛnta na di Kɔlɔmbɔ Nashɔnal Ospital .
Sɔm sayd ɛfɛkt dɛn we pɔsin kin gɛt
Lɛk ɛni mɛrɛsin, Alteplase kin mek yu gɛt sayd ɛfɛkt. Sɔm kin siriɔs ɛn sɔm kin kɔmɔn.
| Sayd ɛfɛkt we pɔsin kin gɛt | Fɔ ɛksplen |
|---|---|
| Sayd ɛfɛkt dɛm we yu fɔ ripɔt to yu dɔktɔ ɔr nɔs wokman dɛm wantɛm wantɛm | |
| Alɛji Riakshɔn dɛn | Skin rash, it, swel na yu fes, lip ɔ tong, i nɔ izi fɔ blo. |
| Di sayn dɛn we de sho se pɔsin de blɔd | Blak ɔ tar stɔl, rɛd ɔ dak brawn urine, vɔmit sɔntin we tan lɛk kɔfi grɔn, rɛd spat na di skin, blɔd we nɔ kɔmɔn frɔm di gam, yay, ɔ nos. |
| Di sayn dɛn we de sho se pɔsin gɛt strok | Yu kin chenj yu yay, yu kin kɔnfyus, i nɔ kin izi fɔ tɔk ɔ ɔndastand, yu ed kin at bad bad wan, yu fes kin swɛt ɔ wik wantɛm wantɛm, yu an ɔ yu leg kin at, yu kin gɛt prɔblɛm fɔ waka, yu ed kin tɔn. |
| Di chenj dɛn we de apin na di at rit | At bit we nɔrmal fɔ slo ɔ fast. |
| Sayd ɛfɛkt dɛm wae nɔr kin siriɔs (bɔt dɛn fɔ ripɔt if dɛn kɔntinyu fɔ de) . | |
| Diziz we pɔsin kin gɛt | I impɔtant fɔ grap sloslo we yu de grap na bed. |
| Fiva | Di bɔdi in tɛmpracha we de go ɔp. |
| Nɔs ɛn vɔmit (Nɔs, Vɔmit) . | Bɔku tɛm, na tin we kin apin fɔ shɔt tɛm nɔmɔ. |
Mɛsej we dɛn kin kɛr go na os
- Alteplase na wan pawaful mɛrɛsin we de sev layf, we de sɔlv di blɔd we de klɔt we i gɛt imejensi lɛk at atak ɛn strok.
- Dɛn kin jɔs gi dis na ɔspitul, ɔnda dɔktɔ in sɔpɔtishɔn. Yu nɔ alaw fɔ kɛr am go na os ɔ yuz am fɔ yusɛf.
- I rili impɔtant fɔ tɛl yu dɔktɔ bɔt ɔl yu mɛrɛsin ɛn ɔl ɔda mɛrɛsin dɛn we yu de tek (inklud vaytamɛn ɛn ɔyl).
- Bikɔs di men tin we kin mek yu gɛt dis mɛrɛsin na we yu de blɔd, dɛn go de wach yu gud gud wan we dɛn de trit yu ɛn fɔ sɔm dez afta dat.
- Notis di wan dɛn we de wok na di ɔspitul wantɛm wantɛm if yu notis ɛnitin we nɔ kɔmɔn, lɛk ed we de at bad bad wan, blɔd we nɔ kɔmɔn, ɔ sayn dɛn we de sho se yu gɛt alɛji.
👩🏽 ⚕️ Ɔda kwɛstyɔn dɛn (FAQ dɛn)
💬 Wetin dɛn de yuz di Alteplase / tPA / Activase vaysin fɔ?
Dis na di mɔs pawaful ‘clot buster / thrombolytic’ drɔg na di wɔl! Ilɛksɛf pɔsin gɛt ‘at atak’ wantɛm wantɛm ɔ in bren klɔt we de mek i paralayz (ischemic stroke) insay sɔm minit (if dɛn briŋ am kam na ɔspitul insay 3 to 4.5 awa), na injɛkshɔn we de sev in layf we dɛn kin gi na di imejensi dipatmɛnt (IV) na ɔspitul fɔ sɔlv di blɔd we dɔn klɔt ɛn sev di pɔsin in layf 100%!
💬 Aw dis injεkshכn (Alteplase) kin sכlv wan bכdi we stכp na di bren/at wantεm wantεm?
Wetin dis de du na fɔ fos fɔ tɔn wi yon bɔdi in yon disɔl mashin (Plasmin)! bכdi kכlכt de fכm we di bכdi sεl dεm de tכn insay wan mεsh we dεn kכl ‘Fibrin’. we dis injεkshכn go insay di bכdi, i de fכnshכn se bכdi de kכlכt (Tissue Plasminogen Activator) εn i de aktibכt di εnzym we dεn kכl plasmin insay am to di maksimal. Dɔn, dɛn kin kɔt di mɛsh (Fibrin) insay smɔl smɔl, sɔlv am, ɛn di blɔd kin bigin fɔ go bak.
💬 Ivin if dis vaysin (tPA) sev pɔsin we sik, wetin na di mɔs siriɔs fatal risk (Black Box Warning)?
Di big denja na ‘Intracranial Hemorrhage’! Dis kin mek di blɔd klɔt, so if smɔl wund de ɛnisay na di bɔdi, i go kɔntinyu fɔ blɔd ɛn di blɔd nɔ go ebul fɔ stɔp. Sɔntɛnde, wan blɔd vesel na di bren kin bɔs ɛn di paralayz kin bɛtɛ, bɔt ivin if di pɔsin we sik blɔd go insay in bren, i kin kil ɛn i kin mek i day wantɛm wantɛm! (Na dat mek dɛn kin rili chɛk di blɔd disɔda/prɛshɔn bifo dɛn gi dis).
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