Wetin na di antifungal resistance? Lɛ wi tɔk bɔt am!

Yu dɔn ɛva yɛri se sɔntɛnde di mɛrɛsin we dɛn kin gi fɔ fungal infɛkshɔn nɔ kin wok fayn lɛk aw yu go want? Sɔntɛnde di antifungal mɛrɛsin we dɔktɔ kin gi nɔ kin wok. Na dat wi kin kɔl antifungal resistance . Dis kin siriɔs smɔl, so lɛ wi tɔk bɔt am simpul wan we yu go ɔndastand. Dis nɔ kin apin bikɔs yu bɔdi de kam fɔ bia wit di mɛrɛsin, bɔt na bikɔs di fɛns insɛf dɔn yus fɔ fɛt di mɛrɛsin.

Wetin na di mɛrɛsin dɛn we de mek pɔsin nɔ gɛt bɛlɛ?

Fɔ tɔk am simpul wan, antifɔngal na mɛrɛsin dɛn we de ɛp fɔ kɔntrol ɔ pul sɔm fɛns infɛkshɔn dɛn we kin kam na wi bɔdi. Yu kin dɔn gɛt yist infɛkshɔn, atlet in fut, jok it, ɛn ringwɔm. Dis na wetin dɛn kin yuz dɛn antifungal mɛrɛsin ya fɔ. Dɛn kin ɛp bak fɔ kɔntrol mɔ siriɔs fɛns infɛkshɔn dɛm we kin afɛkt eria dɛm lɛk di lɔng, bren, ɛn blɔd.

Wetin mek di antifungal resistance na dis kayn prɔblɛm?

Dis na siriɔs wɛlbɔdi prɔblɛm na di wɔl . Jɔs tink bɔt, wi gɛt smɔl nɔmba fɔ antifungal mɛrɛsin dɛn. We fɛns nɔ ebul fɔ tek wan mɛrɛsin, di ɔda tin dɛn we wi kin du nɔ kin izi fɔ du. Sɔntɛnde, ɔda mɛrɛsin dɛn nɔ kin wok fayn, ɔ dɛn kin gɛt siriɔs sayd ɛfɛkt.

dis na wan pat pan di big כmbrela tεm ``Antimicrobial Resistance''. Dat min se nɔto fɔngi nɔmɔ, bɔt baktri, vayrɔs, ɛn parasayt dɛn kin ebul fɔ bia wit drɔgs we dɛn mek fɔ fɛt dɛn. Ivin na kɔntri lɛk Amɛrika, dɛn kin ripɔt se lɛk tri milyɔn pipul dɛn kin gɛt dɛn kayn sik ya we nɔ kin tek drɔgs ɛvri ia, ɛn i pas 35,000 pipul dɛn we kin day. So dis nɔto sɔntin we wi fɔ tek am layt.

Wetin kin mek dis apin?

difrεn rizin dεm de we mek fכn dεm de divεlכp rεsistεns to fכnsayd dεm. Lɛ wi tek wan luk pan wetin dɛn bi:

• Nɔ yuz antifungal mɛrɛsin di rɔŋ we: Dis na di men rizin. Tin dɛm lɛk fɔ nɔ tek di mɛrɛsin fɔ di nɔmba fɔ di de dɛm we di dɔktɔ gi yu ɛn stɔp am af-af, fɔ skip di mɛrɛsin, ɔ fɔ tek di mɛrɛsin we smɔl pas aw yu gi am, kin gi di fɔŋ chans fɔ yus fɔ fɛt di mɛrɛsin. Imajin, if yu gɛt skin fungus ɛn dɛn tɛl yu fɔ tek mɛrɛsin fɔ 7 dez, yu stɔp di mɛrɛsin afta yu dɔn fil fayn insay lɛk 3 dez. Dɔn, di fɛns dɛn we nɔ day ɔltogɛda kin kam bak to layf ɛn adap fɔ mek dɛn nɔ ebul fɔ tek di mɛrɛsin. Di nɛks tɛm we yu gi dɛn da mɛrɛsin de, i nɔ impɔtant! So, i rili impɔtant fɔ tek di doz we dɛn tɛl yu fɔ tek di tɛm we yu gi yu.

• Yuz antibayɔtiks:Di antibayɔtiks we wi kin tek ɔltɛm kin kil bad bad bɔdi. Bɔt dɛn kin kil bak di gud baktri dɛn we de na wi dijestiv sistɛm. Dɔn, di yist we de na di wɔl we dɛn kɔl Kandida kin bigin fɔ gro we dɛn nɔ ebul fɔ kɔntrol am. Dis kin mek yu gɛt yist infɛkshɔn we dɛn kɔl candidiasis, we nid fɔ gɛt mɛrɛsin fɔ fɛt di fɛns. We yu de yuz antibayɔtik ɛn antifɔngal bɔku tɛm, yu kin gɛt di risk fɔ mek yu nɔ ebul fɔ tek ɔl tu di mɛrɛsin dɛn.

• Yuz Fɔngisayd na Ɛgrikalyeshɔn: Fama dɛn kin yuz difrɛn fɛngisayd fɔ mek mold nɔ gro pan tin dɛn we dɛn plant. Pipul dεm wae kin gεt dεn kεmεkal dεm ya bכku tεm kin gεt infεkshכn frכm fכn dεm we nכ de rεsist dεn fכn sayd dεm. Dis na bikɔs di fɛns dɛn we de na da say de kin de pan dɛn kemikal ya ɔltɛm ɛn dɛn kin ebul fɔ bia wit dɛn.

• Naturally resistant: Sɔm kayn fɛns de we nɔ de ɛva ansa to fungicides. Natin nɔ de we dɛn kin yuz fɔ mek dɛn drɔgs dɛn de.

• Spontaneous resistance: Sɔntɛnde, wan fɔngus kin gɛt resistans to wan drɔg we bin de wok fayn bifo. Sɔntɛm i nɔ go pɔsibul fɔ fɛn wan patikyula rizin fɔ dis.

• Transmitted resistance: Dis bak rili impɔtant. Sɔmbɔdi we gɛt wan sik we dɛn kɔl fɔŋ we nɔ de tek drɔgs, we kin pas, kin pas am to ɔda pɔsin. Dɔn, ivin if di pɔsin we jɔs gɛt di sik nɔ ɛva yuz da antifungal de, di infekshɔn we dɛn gɛt nɔ go ansa da mɛrɛsin de.

Udat dɛn de pan denja pas ɔlman?

Pipul wae gɛt wik imyun sistɛm kin gɛt siriɔs fungal infεkshɔn ɛn gɛt rεsistεns to antifungal mεdikeshɔn. Dɛn tin ya na:

• Pipul dɛn we gɛt AIDS
• Pipul wae gɛt ɔtoimyun sik dɛm lɛk lupus
• Di wan dɛn we gɛt kansa
• Pipul dɛn we dɔn gɛt ɔgan transplant
• Pipul dεm we dεn bin gεt stεm sεl (bon mכro) transplant

Bikɔs dɛn pipul ya nɔ kin ebul fɔ fɛt di fɛns infɛkshɔn pas di avɛrej pɔsin, dɛn kin gɛt bɔku risk fɔ gɛt fɛns we nɔ de tek drɔgs.

Wetin na di kɔmplikɛshɔn dɛm we de mek pɔsin nɔ ebul fɔ kil di fɛns?

Sɔm kayn fɛns dɔn bi tin we nɔ kin izi fɔ tek di mɛrɛsin dɛn we dɛn kin yuz fɔ fɛt di fɛns. Wi kin kɔl dɛn tin ya ‘superbugs’ . Ivin if yu tek di mɛrɛsin, dɛn fɛns ya kin kɔntinyu fɔ bɔku ɛn mek yu gɛt infɛkshɔn.

Wi gɛt tri men klas dɛn fɔ antifungal drɔgs: azoles, echinocandins, ɛn polyenes. Fɔng we nɔ ebul fɔ tek wan klas drɔgs nɔ kin ansa ɛni wan pan di tritmɛnt dɛn we dɛn de gi naw.

Wetin na dɛn ‘superbugs’ ya?

difrεn fכn infεkshכn dεm de we at fכ trit εn dεn de fכl insay di kכtכgכri fכ ‘super fכn':

• Aspergillus fumigatus: Dis na wan kayn mold. I kin mek pɔsin gɛt wan sik we dɛn kɔl aspergillosis. Na lɛk tu ɔndrɛd tawzin pipul dɛn ɔlsay na di wɔl kin gɛt dis sik ɛvri ia, mɔ bay we dɛn de blo di spay dɛn we de kɔmɔt na dis mol. Dis infεkshכn de kam bכku bכku wan we i de rεsist to azole fכngisayd dεm.

• Kandida: Dis kayn yist de liv na wi skin ɛn insay wi bɔdi. Bɔt if Kandida go insay di blɔd, i kin mek pɔsin gɛt wan sik we de mek pɔsin in layf de pan denja we dɛn kɔl kandidemia. Dis infεkshכn tu nכ de rεspכnd fayn to azole mεdikeshכn dεm.

• Candida glabrata: C. glabrata na wan fכns we de afekt di urinary tract. I de bi resistant to ɔl tu di azoles ɛn echinocandins, we de limited sef tritmɛnt opshɔn fɔ di sik pipul dɛn.

Wetin na `Candida auris`?

Candida auris (C. auris) na wan nyu ɛn denja ‘superbug’ we dɛn bin fɔs no insay 2009. I dɔn skata kwik kwik wan ɔlsay na di wɔl ɛn i dɔn mek prɔblɛm. Di antifungal drɔgs we dɛn kin yuz fɔ trit Candida infɛkshɔn nɔ kin wok ɔltɛm agens dis kayn fɔngus. Sɔm strayn dɛn fɔ C. auris nɔ kin gɛt bɔku drɔgs . Dis min se dɛn nɔ go ebul fɔ kɔntrol dɛn wit ɛni wan pan di antifungal drɔgs dɛn we de naw.

Dis fכns kin go insay di bכdi εn afekt di at εn bren. If dis apin, pas wan pat pan tri pan di wan dɛn we gɛt di sik kin day. Dis fεns kin spre izi wan na כspitul εn nכs os dεm. I kin pas bay we yu de nia pɔsin we gɛt di sik ɔ we yu tɔch say we gɛt di fɛns pan am. Dis fεns kin liv pan surface fכ wik εn i rili at fכ kil.

Aw dɛn kin trit di infɛkshɔn dɛn we nɔ kin gɛt antifɔngal?

If wan klas fɔ antifungal mɛrɛsin nɔ wok, yu dɔktɔ go tray difrɛn klas. Bɔt, lɛk aw a bin dɔn tɔk bifo tɛm, di tritmɛnt dɛn we kin wok fayn fɔ di antifɔngal nɔ bɔku. If wan infekshɔn nɔ de ansa to antifungals, dɔktɔ dɛn kin tray ɔda mɛrɛsin dɛn. Bɔt, i sɔri fɔ no se, dɛn mɛrɛsin dɛn de kin gɛt mɔ siriɔs sayd ɛfɛkt dɛn .

Wi go ebul fɔ mek dis tin nɔ apin?

Yɛs, tin dɛn de we wi kin du! Di bɛst we fɔ mek yu nɔ gɛt antifungal na fɔ tek antifungal mɛrɛsin jɔs lɛk aw yu dɔktɔ tɛl yu.

If yu gɛt prɔblɛm fɔ mɛmba fɔ tek yu mɛrɛsin, sɛt mɛsej fɔ mɛmba yu na yu fon. If yu mis wan doz, kɔl yu dɔktɔ wantɛm wantɛm ɛn aks wetin fɔ du. Bɔrku tɛm, i bɛtɛ fɔ tek di nɛks doz jɔs lɛk aw yu mɛmba.

Mɛmba se, di rεsistεns to fεnshכn kin apin fכ difrεn rizin dεm. Sɔntɛnde, i kin apin wantɛm wantɛm ɛn we yu nɔ bin de tink se i go apin. Ɔ, i kin bi bikɔs dɛn de yuz antibayɔtik pasmak, ɔ dɛn nɔ yuz fungicides di rayt we. Pipul wae gɛt wik imyun sistɛm kin gɛt di ay risk. Sɔm ‘superbugs’ nɔ kin ebul fɔ gɛt standad tritmɛnt. So, fɔ yuz di mɛrɛsin kɔrɛkt wan na di impɔtant we fɔ ridyus dis prɔblɛm.

Fɔ dɔn, tin dɛn we wi fɔ mɛmba

So, dis antifungal resistance we wi bin de tok bɔt tide, dat na ``Antifungal Resistance'', na sɔntin we wi ɔl nid fɔ pe atɛnshɔn to. I tan lɛk se di ɛnimi de yus to di wɛpɔn dɛn we wi de yuz.

• Fɔ fala yu dɔktɔ in instrɔkshɔn dɛn gud gud wan: Tek di mɛrɛsin we yu dɔktɔ tɛl yu fɔ tek, fɔ di rayt nɔmba fɔ di de dɛn ɛn di rayt we fɔ tek am. Nɔ ridyus, inkrisayz, ɔ stɔp fɔ tek am af-af.
• Nɔ yuz antibayɔtik we nɔ nid: Antibayɔtik nɔ kin wok fɔ vayral infɛkshɔn lɛk di kɔmɔn kol. Nɔ tek dɛn we yu nɔ gɛt dɔktɔ in advays.
• Tek kia fɔ klin: Ɛspɛshali na ɔspitul ɛnvayrɔmɛnt, ɔ we yu de nia pɔsin we in imyun sistɛm wik, fɔ tek kia ɔf klin kin protɛkt yu frɔm sik dɛn we kin pas.
• Yu fɔ no: I rili impɔtant fɔ no bɔt dɛn tin ya ɛn fɔ tich ɔda pipul dɛn.

A op se dis infɔmeshɔn go ɛp yu. If yu gɛt ɛni ɔda kwɛstyɔn bɔt dis, nɔ shek fɔ aks dɔktɔ. Stay wit wɛlbɔdi!

` antifכngal rεsistεns, antifכngal rεsistεns, fכn infεkshכn, supεrbכg, kandida auris, drog rεsistεns, fכn sik dεm