Yu gɛt asma? Yu kin de yuz yu inhala lɛk aw dɛn tɛl yu fɔ tek ɛn tek ɔda mɛrɛsin, bɔt yu asma sayn dɛn nɔ de bɛtɛ. If yu de gɛt swɛt ɔltɛm, yu chɛst de tayt, ɛn yu de kɔf, yu kin gɛt smɔl to siriɔs asma. Dis nyu, advans tritmɛnt we dɛn kɔl ‘Biologic Therapy’, dɛn kin yuz fɔ dɛn kayn asma kɔndishɔn ya we at fɔ kɔntrol.
Fɔ tɔk am simpul wan, wetin na Bayolojikal Tɛrapi?
Dis na wan mɔdan, targeted tritmɛnt fɔ siriɔs asma. Pan ɔl we di tin dɛn we dɛn kin yuz ɔltɛm fɔ inhala kin mek di say dɛn we pɔsin kin blo big fɔ sɔm tɛm ɛn mek i izi fɔ blo, bayolojikal tɛrapi kin go dip.
Imajin, di men rizin we mek wi gɛt asma na inflamɛns na di aywe we kin kam bikɔs ɔf sɔm ɔda tin dɛn we di bɔdi in imyun sistɛm de du. So wetin dis bayolojikal dכg dεm de du na fכ tכk to spεsifi k antibodi dεm, sεl dεm כ mכlikul dεm na di bכdi we de kכntribyut to da inflameshn de εn stכp dεn aktiviti. Bikɔs ɔf dis, dɛn kin kɔntrol asma na wan bɛsik lɛvɛl.
Dɛn kin gi dis tritmɛnt tu men we dɛn. wan na lεk injεkshכn כnda di skin (subcutaneous injection) εn di כda wan na lεk intravenous (IV infusion) infushכn.
Di impɔtant tin na dat dis nɔto tritmɛnt fɔ insɛf. Yu fɔ yuz am togɛda wit di inhala we yu dɔn gɛt ɛn ɔda mɛrɛsin dɛn we de mek yu gɛt asma.
Udat dis tritmɛnt fayn fɔ?
Bayolojikal tɛrapi nɔto tritmɛnt fɔ ɔl di wan dɛn we gɛt asma. Yu dɔktɔ go tink bɔt sɔm tin dɛn bifo i tɛl yu bɔt dis tritmɛnt. Di tebul we de dɔŋ ya go gi yu gud aidia.
| Situeshɔn dɛm wae dɛn kin rifer yu fɔ Bayolojikal Tɛrapi | |
|---|---|
| Nɔto di mɛrɛsin we dɛn gi am fɔ kɔntrol am | If dɛn nɔr kɔntrol yu asma simptom pan ɔl we yu de yuz yu inhala ɛn ɔda mɛrɛsin dɛn we dɛn dɔn gi yu kɔrɛkt wan. |
| Di rizɔlt fɔ di blɔd tɛst | If yu gɛt bɔku bɔku Eosinophils (wan wayt blɔd sɛl we de mek di lɔng dɛn inflamɛns) ɔ IgE (wan antibodi we gɛt fɔ du wit alɛji) na yu blɔd. |
| Kɔz dɛm wae de mek di sik wɔs | If yu no wetin de mek yu gɛt asma ɛn avɔyd am, bɔt yu sayn dɛn de kɔntinyu. |
| Di sayn dɛn we kin apin ɔltɛm | If yu wek midul nɛt wit kɔf, ɔ if yu yuz yu rɛskɔ inhala pas tu tɛm insay di wik. |
| Di tin dɛn we kin mek pɔsin wɔs ɔltɛm | If yu fɔ tek kɔtikosterɔyd pils pas tu tɛm insay di ia ɔ yu fɔ go na di ETU (Imejɛnsi Tritmɛnt Yunit). |
| Fɔ go na ɔspitul | If yu fɔ de na ɔspitul ɛn gɛt tritmɛnt bikɔs ɔf asma. |
Us kayn bayolojikal drɔgs de fɔ asma?
Bɔku kayn bayolojikal mɛrɛsin dɛn de we dɛn dɔn gri fɔ te naw. Ɛni wan pan dɛn de wok difrɛn we smɔl. Yu dɔktɔ go pik di mɛrɛsin we go fayn fɔ yu bay di kayn asma we yu gɛt ɛn di rizɔlt fɔ yu blɔd tɛst.
| Nem fɔ di drɔg | Fɔnkshɔn ɛn di we aw dɛn de gi am | Kɔmɔn sayd ɛfɛkt dɛn |
|---|---|---|
| Omalizumab (Xolair®) we gɛt di sik. | I de trit asma we pɔsin kin gɛt we i gɛt alɛji. Dɛn kin injekt am ɔnda di skin ɛvri 2-4 wik. | Mɔsul pen, jɔyn pen, taya pasmak, swel/pen na di say we dɛn injɛkshɔn. |
| Mepolizumab (Nucala®) we gɛt di sik. | I de trit eosinophilic asma. Dɛn kin injekt am ɔnda di skin ɛvri 4 wik. | Ed pen, bak pen, wik, taya, swel/pen na di say we dɛn injεkt. |
| Reslizumab (Cinqair®) we gɛt di sik. | I de trit eosinophilic asma. Dɛn kin gi am insay di bɛlɛ (IV) ɛvri 4 wik. | Trot we de at, pen na di mɔsul dɛn. |
| Benralizumab (Fasenra®) we dɛn kɔl di . | I de trit eosinophilic asma. Dɛn kin gi di fɔs 3 dos dɛn ɛvri 4 wik, dɔn ɛvri 8 wik. | Ed we de at, trot we de at. |
| Dupilumab (Dupixent®) we gɛt di sik. | I de trit eosinophilic asma ɛn ɔda tin dɛn we kin kam wit inflamɛns. Dɛn kin injekt am ɛvri 2 wik. | Trot de at, swɛlin/pen na di say we dɛn injɛkshɔn, di wayt blɔd sɛl dɛn de bɔku. |
| Tezepelumab (Tezspire®) we gɛt di sik. | Wan nyu mɛrɛsin fɔ siriɔs asma. I de mek di inflamɛns nɔ bɔku. Dɛn kin injekt am ɛvri 4 wik. | Trot we de at, bak pen, jɔyn pen. |
Aw lɔng dis tritmɛnt kin tek?
Bɔrku tɛm, dis na tritmɛnt fɔ lɔng tɛm. I kin tek at le 4-6 mɔnt fɔ no fɔ tru if dis mɛrɛsin de wok fɔ yu. So i impɔtant fɔ peshɛnt wit di tritmɛnt we yu de gi yu.
A nid fɔ kɔntinyu fɔ yuz mi inhala?
Yɛs, fɔ tru.Dis na di tin we impɔtant pas ɔl. Ivin afta yu dɔn bigin fɔ yuz bayolojikal tɛrapi, nɔ ɛva stɔp fɔ tek yu inhala ɛn ɔda mɛrɛsin dɛn we yu dɔktɔ gi yu. As tɛm de go, if yu dɔn kɔntrol yu asma fayn fayn wan, yu dɔktɔ go disayd fɔ ridyus di doz we yu de yuz fɔ inhala. Bɔt dɛn fɔ jɔs du dis ɔnda dɔktɔ in advays.
Wetin na di bɛnifit ɛn prɔblɛm dɛn we dis tritmɛnt de gi?
Lɛk ɛni tritmɛnt, dis wan gɛt bɛnifit dɛn ɛn i gɛt smɔl smɔl prɔblɛm dɛn bak.
Di men bɛnifit dɛn we yu kin gɛt:
- I de ridyus inflamɛns na di respiratory tract ɛn i de kɔntrol di asma simptom dɛn fayn fayn wan.
- Di kol ɛn kɔf we yu kin gɛt ɔltɛm go stɔp.
- Yu go ebul fɔ du ɛksɛsayz ɛn dɔn di wok dɛn we yu de du ɛvride ɛn yu nɔ go nid fɔ wok tranga wan lɛk aw yu bin de wok trade.
- Di nɔmba fɔ di tɛm dɛn we yu kin wek na nɛt kin go dɔŋ.
- Di nid fɔ go na di ETU (Imergency Treatment Unit) smɔl smɔl go stɔp.
- Di kwaliti fɔ layf de bɛtɛ pasmak.
Di prɔblɛm dɛn we kin apin:
- Siriɔs alɛji: Na smɔl tɛm nɔmɔ, sɔm pipul dɛn kin gɛt siriɔs alɛji (anaphylaxis). Dis na di rizin we mek dɛn kin gi di fɔs fɔs dos dɛn na ɔspitul ɔ klinik ɔnda dɔktɔ in sɔpɔtishɔn.
- Risk fɔ parasayt infɛkshɔn: Mɛrɛsin dɛm we de ridyus di eosinophils kin ridyus di bɔdi in ebul fɔ fɛt parasayt dɛm, mɔ di ɛlminth dɛm. So yu dɔktɔ go tek dat na kɔna bifo i bigin dis tritmɛnt.
Impɔtant: Nɔ stɔp fɔ tek dis mɛrɛsin wantɛm wantɛm fɔ ɛni rizin if yu dɔktɔ nɔ advays yu. If yu du dat, dat kin mek yu asma simptom dɛn wɔs.
Ustɛm fɔ tɔk to yu dɔktɔ
Insay dɛn kayn tin ya, mek shɔ se yu go to yu dɔktɔ ɛn tɛl am.
- If di sayn dɛm fɔ asma nɔr bɛtɛ ɔr wɔs afta sɔm mɔnt wae dɛn dɔn trit yu.
- If nyu alɛji simptom dɛm (e.g. skin rash, it) de sho.
- If yu gɛt ɛni kwɛstyɔn ɔr tin we de mɔna yu bɔt di tritmɛnt.
Yu kin gɛt dis tritmɛnt pan spɛshal dɔktɔ in rɛkɛmɔndeshɔn, frɔm spɛshal yunit na ɔspitul (infusion sɛnta) ɔ frɔm spɛshal dɔktɔ in klinik. Dis tritmɛnt kin dia smɔl. Bɔt yu kin tɔk to yu dɔktɔ bɔt am ɛn fɛn ɔda tin dɛn.
Mɛsej we dɛn kin kɛr go na os
- Bayolojikal Tɛrapi na wan advans tritmɛnt we dɛn kin yuz fɔ siriɔs asma kɔndishɔn we at fɔ kɔntrol wit mɛrɛsin ɔltɛm.
- Dis nɔto mɛrɛsin fɔ asma, bɔt i kin ɛp fɔ kɔntrol di sik fayn fayn wan.
- We yu de gɛt dis tritmɛnt, i impɔtant fɔ kɔntinyu fɔ yuz yu inhala ɛn ɔl ɔda mɛrɛsin dɛn we yu dɔktɔ dɔn tɛl yu.
- Dɛn go no if dis tritmɛnt fayn fɔ yu ɔ nɔ fayn fɔ yu afta dɛn dɔn tink bɔt yu sik dɛn ɛn sɔm patikyula blɔd tɛst ripɔt dɛn.
- Bikɔs i kin tek sɔm mɔnt fɔ mek di rizɔlt fɔ di tritmɛnt sho, i rili impɔtant fɔ peshɛnt ɛn fala di instrɔkshɔn dɛn we di dɔktɔ gi yu we yu de trit am.
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