Yu de fil se yu wik? Yu an ɛn fut dɛn de tingling? Lɛ wi lan bɔt CIDP (Krɔnik Inflammatory Demyelinating Polyneuropathy)!

Sɔntɛnde yu kin fil taya bad bad wan, yu an ɛn yu fut kin swɛla, ɔ yu kin fil lɛk se yu de swɛt? Sɔntɛnde, yu nɔ kin pe atɛnshɔn tumɔs pan dɛn tin ya. Bɔt nɔr kin bɔrku, dɛn sayn ya kin bi sayn fɔ sɔmtin wae rili siriɔs. Wan pan dɛn kayn tin ya we nɔ kin apin bɔt we impɔtant fɔ no bɔt na in dɛn kɔl CIDP (Chronic Inflammatory Demyelinating Polyneuropathy) . Pan ɔl we i go tan lɛk se di nem lɔng smɔl, lɛ wi kip am simpul.

Wetin na CIDP (Krכnik Inflammatory Demyelinating Polyneuropathy)?

Pan ɔl we dis nem kin tan lɛk se i kɔmplikt smɔl, if wi brok di minin we i min, wi kin gɛt bɛtɛ aidia bɔt dis sik.

• Kronik: Dis min "lɔng tɛm." Dis min se CIDP nɔ de kam wantɛm wantɛm ɛn i kin bɛtɛ kwik kwik wan. I kin gro sloslo, fɔ at le et wiks. Sɔntɛnde, de sik kin stɔp ɛn afta sɔm mɔnt ɔ ivin sɔm ia. I tan lɛk prɔblɛm we kin apin ɔltɛm.

• Inflammatory: Dis min "inflammatory" . We wi gɛt injuri sɔnsay na wi bɔdi, i kin swel ɛn tɔn rɛd, nɔto so? Na dat i bi. Bɔt insay CIDP, dis inflamɛns kin apin bikɔs ɔf sɔm prɔblɛm na wi yon bɔdi in imyun sistɛm . Fɔ tɔk am simpul wan, di sojaman dɛn we fɔ protɛkt wi bɔdi kin bigin fɔ atak wi yon nerv dɛn bay mistek. dis dεn kכl am ``Autoimmune Attack'' . Di inflamɛns we pasmak we dis kin mek kin pwɛl wi periferik nɛv dɛn . dis pεriferal nεv dεm na di nεv dεm we de kכmכt frכm di bren εn di spεnal kכd.

• Demyelinating: Dis na smɔl dip wɔd. Wi nyuron dɛn gɛt wan tin we de protɛkt dɛn rawnd dɛn. I tan lɛk plastic sheath we de rawnd ilɛktrik waya. Dɛn kɔl dis kɔva di ` (Myelin Sheath)` . dis maylin sheath na in de alaw di nεv mεsej fכ travul kwik εn kכrekt wan. `(Demyelinating)` min se di maylin sεt dεn dכn dכn כ damej. Dɔn, jɔs lɛk we dɛn pul di plastic we de na di waya, di kɔrɛnt kin lik, ɛn di mɛsej dɛn we de na di nerv nɔ kin travul fayn.

• Polinyuropati: "Poly" min "bɔku." "Nyuropati" min se di nerv dεm dεn dכn pwεl. Polyneuropathy min se plεnti pεrifεral nεv dεm na di bכdi de damej di sem tεm. Dis kin mek yu gɛt difrɛn prɔblɛm dɛn lɛk we yu mɔsul dɛn wik, yu nɔr de fil fayn, ɛn yu nɔr de fil fayn.

so, fכ sכmtεm, CIDP na lכng tεm kכndyushכn we di maylin sεt we de rawnd di pεrifεral nεv dεm de pwεl bikoz fכ wan mכlfunshכn na wi כwn imyun sistεm, we de rεsult in di disfכnkshכn fכ plεnti nεv dεm. Yu ɔndastand?

Wetin na di difrɛns bitwin Guillain-Barré Syndrome (GBS) ɛn CIDP?

Yu go mɔs biYu kin dɔn yɛri bɔt ` (Guillain-Barré Syndrome)` ɔ ` (GBS) .` Di sik we dɛn kɔl CIDP rili fiba GBS. Dɔktɔ dɛn kin tek CIDP as wan we fɔ GBS fɔ lɔng tɛm. GBS na sik bak we nɔ kin apin so ɔltɛm we wi imyun sistɛm kin atak di periferik nɛv dɛm.

Bɔt di men difrɛns na tɛm. Di wɔs tin fɔ GBS kin kam tu to tri wik afta di sik bigin. Bɔt bɔku pipul dɛn kin wɛl smɔl smɔl afta dat. Bɔt CIDP kin las fɔ lɔng tɛm. Di sik kin wɔs smɔl smɔl fɔ at le et wiks .

Aw kɔmɔn tin fɔ CIDP?

CIDP na rili wan kɔndishɔn we nɔ kin apin so ɔltɛm . Di wan dɛn we de stɔdi bɔt dis tɔk se di nɔmba fɔ nyu wan dɛn we gɛt CIDP na Amɛrika de bitwin 0.8 ɛn 8.9 pan ɛvri 100,000 pipul dɛn ɛvri ia. Dis rεnj big smɔl, bikɔs CIDP kin afɛkt difrɛn pipul dɛn difrɛn we, ɛn bikɔs i at fɔ no di sik.

CIDP kin divɛlɔp pan ɛni ej.

Wetin na di sayn dɛm fɔ CIDP?

Di sayn dɛm fɔ CIDP kin difrɛn difrɛn wan bay di kayn. Bɔt di tin we kin apin mɔ na di mɔsul dɛn we kin wik ɛn we kin las fɔ at le et wiks. Dis kin afɛkt ɔl tu di say dɛn na di bɔdi ikwal wan. Speshal wan:

• Di mɔsul dɛn na di hip ɛn di shɔl eria
• di mכsul dεm na di sכlda εn di כp an εria
• Palm ɛn finga dɛn
• Fut ɛn fut finga dɛn

Imajin, wantɛm wantɛm i nɔ kin izi fɔ yu fɔ grap na chia, yu kin fil lɛk se yu nɔ ebul fɔ klaym stej, ɔ i nɔ kin izi fɔ yu fɔ kɔm yu ia ɔ ol kɔp. Tin dɛn lɛk dis kin apin.

Ɔda sayn dɛm wae yu kin si na:

• Atrofi fɔ di mɔsul dɛn we dɛn afɛkt
• Di finga ɛn fut finga dɛn kin swɛla, kin swɛt, ɔ nɔ kin fil fayn (Paresthesia) .
• I nɔ kin izi fɔ mek yu bɔdi balans ɛn nɔ gɛt bɛtɛ kɔdineshɔn (lɛk fɔ stɔp) .
• I nɔ izi fɔ waka ɔ i nɔ ebul fɔ waka atɔl
• dip tεndon rεflεks dεm we de lכs כ wik (dis na wetin dכkta go tεst fכ bay we i tap di kכn wit sכm hama) .
• Nyuropatik Pen we pɔsin kin gɛt. Dis na pen wae kin fil lɛk fɔ bɔn ɔr ilɛktrik shɔk.

Nɔr kin bɔrku, yu kin si bak sɔm kayn sik lɛk:

• I nɔ izi fɔ swɛla (Dysphagia) ɛn di ɔpa nɛk wik
• Dabl Vishɔn

Dɛn sayn ya kin chenj as tɛm de go. Dɛn kin bigin smɔl smɔl, ɔ dɛn kin go bifo kwik kwik wan. Sɔntɛnde, dɛn kin kam ɛn go, dɛn kin stɔp afta sɔm dez, dɔn dɛn kin kam bak. If yu gɛt dɛn sik ya, i impɔtant fɔ go to dɔktɔ kwik kwik wan.If yu no di sik kwik kwik wan ɛn trit yu, dat kin ɛp yu fɔ wɛl.

Difrɛn kayn CIDP dɛn de?

Yes, difrɛn kayn CIDP de, ɛn dɛn simptom dɛn difrɛn smɔl.

di kayn we we kכmכn pas כl na di tכpikכl CIDP , we de mek di mכsul dεm wik εn di sεns dεm (lεk fכ sכmtεm) na di tu say dεm na di bכdi.

Sɔm atypical variant dɛn na:

• ` (Multifocal Motor Neuropathy)`: Dis involv כnli mכsul wik. Dis wikɛdnɛs nɔ kin simɛtrik bak, we min se i kin afɛkt wan eria nɔmɔ na wan say na di bɔdi, ɔ sɔm eria dɛn difrɛn we dɛn.
• ` (Lewis-Sumner Syndrome): Dis involv כl tu di asimεtrik mכsul dεm we wik εn di sεns simptom dεm.
• ` (Pure Sensory CIDP)`: Dis kin mek yu nɔ gɛt bɛtɛ trɛnk, pen, yu gɛt prɔblɛm wit balans, ɛn yu nɔ de waka fayn. Bɔt no mɔsul dɛn nɔ de we wik.
• `(Pure Motor CIDP):`: insay dis, yu kin si di mכsul dεm we wik εn di lכs fכ rεflεks we de afekt di tu say dεm na di bכdi, bכt nכ sεns simptom dεm de.

Risach pipul dεm stil de stכdi כda vεryכnt dεm fכ CIDP.

Wetin kin mek pɔsin gɛt CIDP?

As wi bin dɔn tɔk bifo tɛm, sɔm pipul dɛn we de stɔdi bɔt dis biliv se CIDP kin kam bikɔs wi imyun sistɛm nɔ de wok fayn . pan ɔl we dɛn nɔ no yet di rayt kɔz, wi imyun sistɛm de si di maylin sheath as ɛnimi ɛn afta dat i bigin fɔ atak am (wan ɔtoimyun riakshɔn).

di maylin sεl na di prכtektiv layεr we de rawnd wi nεv sεl dεm. i de rap rawnd di lכng pat pan di nεv fayba (akson). Maylin na wetin de alaw ilɛktrik impuls fɔ travul along di nerve fayn fayn wan. we di maylin dכn pwεl, dεn ilektrikal impuls dεm ya de travul sכmtεm sכmtεm, כ dεn de lכs כlsay. Den di "messages" no get fo wia dem sopoz fo go. Na dat de mek di sayn dɛm fɔ CIDP.

Imajin wan ilɛktrik waya we dɛn dɔn inshɔl fayn fayn wan. I de kɔndɔkt kɔrɛnt fayn fayn wan. Bɔt wetin go apin if di plastic sheath pan da waya de kɔmɔt na say dɛn? Di kɔrɛnt de lik, ɔ i nɔ de flɔ fayn, nɔto so? Na dat kin apin we di maylin sheath dɔn pwɛl.

Aw dɛn kin no CIDP?

Fɔ no CIDP kin tranga bikɔs difrɛn kayn dɛn gɛt difrɛn sayn dɛm. Fɔ no if yu gɛt CIDP, yu dɔktɔ go:

• Dɛn go tek tɛm lisin to yu sayn dɛm ɛn aks bɔt yu mɛdikal histri .
• Dɛn kin du wan ɛgzam fɔ di bɔdi ɛn wan ɛgzam fɔ di nyurolɔjik .
• Dɛn kin ɔda fɔ du sɔm spɛshal tɛst fɔ kɔnfirm di sik ɔ fɔ pul ɔda sik dɛn.

Us tɛst dɛn kin yuz fɔ no CIDP?

Dis na di tɛst dɛm we kin ɛp fɔ kɔnfɔm CIDP ɛn pul ɔda kɔz dɛm:

• Ilɛktromayografi (EMG) ɛn Nɛv Kɔndɔkshɔn Tɛst: Dɛn tɛst ya de luk aw yu mɔsul dɛn gɛt wɛlbɔdi ɛn aw dɛn de wok ɛn di nerv dɛn we de kɔntrol dɛn. dis tεst dεm de yus spεshal fכ luk fכ demyelinating chenj dεm (slow transmishכn fכ nεv signal dεm, blכk dεm, εtk) lεk CIDP. dis kin εp fכ difrεnt CIDP frכm כda kכmכn tכp dεm fכ polinyuropathies.

• Spinal Tap / Lumbar Puncture: Insay dis tεst, dכkta de put sכm sכm nidul insay yu lכw bכk εn tek sεmpl fכ yu sεribrospεnal fכluid (CSF) . Dɛn kin sɛn dis sampul to wan lab fɔ mek dɛn tɛst am. pan 85% to 90% pan pipul dεm we gεt CIDP, di wayt bכdi sεl kכnt nכmal, bכt di protin lεvεl de εlevεt. Ɔda abnɔmal tin dɛn na di CSF kin sho se ɔda kɔndishɔn de.

• Magnetic Resonance Imaging (MRI) skan fכ di lכw bכk: If di nεv rכt dεm na yu lכw bכk abzכp wan kכntrast day we dεn de du MRI skan, i kin εp fכ no CIDP.

• Blɔd Tɛst: Yu dɔktɔ kin ɔda fɔ mek dɛn du blɔd tɛst fɔ no ɔda tin dɛn we kin mek pɔsin gɛt nyuropati, lɛk dayabitis, vaytamɛn we nɔ gɛt bɛtɛ vaytamɛn, tayroyd sik, Laym sik, HIV/AIDS, ɛn limfoma. Dɛn kin chɛk bak fɔ sɔm antibodi dɛm we dɛn dɔn si se gɛt fɔ du wit CIDP.

• Nεv Bayopsi: Na sכm tεm we dכkta kin rεkכmand fכ nerve biopsy, we dεn kin pul wan pat pan di nerve εn chɛk am fכ si if di myelin sheath dεn dכn pwεl.

Wetin na di tritmɛnt dɛm fɔ CIDP?

Tri men (fɔs-layn) tritmɛnt dɛn de fɔ CIDP:

• Kɔtikosterɔyd: Stɛroyd mɛrɛsin dɛn lɛk prɛdnisolon, kin ɛp fɔ ridyus di inflamɛns. Fɔ bɔku pipul dɛn, dɛn stɛroyd ya nɔmɔ kin ɛp fɔ ridyus di sik. Bɔt stɛroyd kin gɛt siriɔs sayd ɛfɛkt, so i nɔ kin yuz dɛn mɛrɛsin ya fɔ lɔng tɛm. Yu dɔktɔ kin gi yu ɔda mɛrɛsin dɛn bak (immunosuppressants) wit stɛroyd.

• Plasma Exchange / Plasmapheresis: Insay dis tritmɛnt, wan mashin kin separet di plasma frɔm yu blɔd, trit am, dɔn i kin gi bak di plasma ɛn blɔd bak to yu bɔdi. Fɔ tɔk am simpul wan, i de filta di bad bad antibodi dɛn we de na di plasma we de atak yu nerv dɛn. Bɔku tɛm, i kin jɔs wok fɔ sɔm wiks nɔmɔ fɔ chenj di plasma. Yu kin nid fɔ gɛt dis tritmɛnt ɛn ɔf fɔ sɔm mɔnt, ɔ ivin fɔ lɔng tɛm.

• Intravenous Immunoglobulin Therapy (IVIG): Insay dis tritmεnt, dεn kin gi protin dεm we dεn kכl immunoglobulins (protein dεm we wi imyun sistεm de mek nכmal fכ atak invayda dεm) intravenous (IV). Dɛn kin gɛt dis imyunoglobulin frɔm di blɔd fɔ bɔku bɔku pipul dɛn we gɛt wɛlbɔdi. IVIG kin ridyus di damej we yu imyun sistɛm de du to yu nerv dɛm. Dɛn kin gi IVIG insay rili ay dos fɔs, ɛn yu kin nid fɔ gɛt dis tritmɛnt wan wan tɛm fɔ mɔnt, ɔ ivin ia.

Naw, di wan dɛn we de du risach de stɔdi ɔda tritmɛnt dɛn fɔ CIDP. Yu kin gɛt di chans bak fɔ tek pat pan klinik trial fɔ CIDP. Tɔk to yu dɔktɔ bɔt dis.

Aw layf tan lɛk wit CIDP? (Prɔgnosis) .

Aw di sik kin de fɔ lɔng tɛm kin dipen pan sɔm tin dɛm:

• Yu ej we CIDP bigin.
• Aw di sik kin kam ɛn di kayn sik .
• Aw dɛn bin no di sik kwik kwik wan ɛn bigin fɔ trit am .
• Aw yu bɔdi kin ansa fɔs we yu gɛt tritmɛnt.

Na lɛk 90% pan di pipul dɛm wae gɛt CIDP kin wɛl wit tritmɛnt. Bɔt lɛk 50% pan pipul dɛn kin gɛt dis sik bak. In jɛnɛral, di lɔng tɛm prɔgnosis fɔ pipul dɛm we dɛn no se gɛt CIDP we dɛn yɔŋ, fayn. If yu nɔ gɛt ɛni tritmɛnt fɔ CIDP, pɔrmɛnt nerv damej kin apin, we kin mek yu gɛt sɔm disabled.

Yu dɔktɔ go ebul fɔ gi yu gud aidia bɔt wetin fɔ ɛkspɛkt fɔ go bifo bay yu patikyula kɔndishɔn.

Yu tink se CIDP de mek di layf we pɔsin de liv shɔt?

CIDP nɔto sik we de kil pɔsin. Pipul wae gɛt dis sik kin gɛt di sem layf lɛk pɔrsin wae nɔr gɛt dis sik. So natin nɔ de fɔ wɔri bɔt.

Yu tink se dɛn kin ebul fɔ stɔp CIDP?

Bikɔs di wan dɛn we de stɔdi bɔt dis nɔ dɔn fɛn wan patikyula kɔz fɔ CIDP yet, naw dɛn nɔ no we fɔ mek di sik nɔ kam.

Ustɛm a fɔ go to dɔktɔ? / Ustɛm a fɔ go na imejensi rum?

If dɛn dɔn no se yu gɛt CIDP, yu fɔ go to yu dɔktɔ ɔltɛm fɔ wach yu sik ɛn gɛt tritmɛnt. Di CIDP simptom kin kam ɛn go fɔ mɔnt ɔ ivin ia, so i kin nid fɔ kɔntinyu fɔ gɛt tritmɛnt.

Na smɔl tɛm nɔmɔ, CIDP kin afɛkt di mɔsul dɛn we yu nid fɔ blo . If yu gɛt prɔblɛm fɔ blo , kɔl 911 (ɔ yu lokal imejensi nɔmba) wantɛm wantɛm, ɔ go na di imejensi rum we de nia yu. Dis na imejensi.

Fɔ dɔn, tin dɛn we wi fɔ mɛmba

E kin mek yu frayd fɔ fil lɛk yu nɔr ebul fɔ kɔntrol yu bɔdi. Bɔt di gud nyus na dat , dɛn kin trit di sayn dɛn we de sho se pɔsin gɛt CIDP (Chronic Inflammatory Demyelinating Polyneuropathy), mɔ if yu bigin fɔ trit am kwik. Mɛmba se yu mɛdikal tim de wit yu ɛvri step na di we fɔ dil wit dis sik. So tek yu at ɛn fala yu dɔktɔ in advays.

` CIDP, Nyuropati, Mɔsul Wiknɛs, Nɔmbnɛs, Imyun Sistɛm, Maylin, Nɛvɔs Sistɛm, CIDP Tritmɛnt, Kronik Inflammatory Demyelinating Polyneuropathy