Yu gɛt kwɛstyɔn bɔt kɔtisol? Lɛ wi no dis ‘stress hormone’ ditayli!

Yu go mɔs dɔn yɛri di wɔd “ kɔtisol , ” mɔ we yu de tɔk bɔt “ strɛs .” Bɔt kɔtisol nɔto jɔs "strɛs ɔmon." Infakt, na impɔtant ɔmon we de ple rili impɔtant pat na wi bɔdi. So, tide, lɛ wi tɔk bɔt kɔtisol insay wan simpul we we yu go ɔndastand.

Wetin na kɔtisol? Yu tink se na rili jɔs ‘stres ɔmon’?

fכ simpul wan, kכtisol na כmon we wi adrenal gland dεm de mek εn kכl am – tu sכm sכm gland dεm we de oba di kidni dεm. Na wan kayn stεrɔyd ɔmon we dɛn kɔl glukokɔtikoyd .

Yɛs, lɛk aw yu go tink, kɔtisol gɛt sɔntin fɔ du wit strɛs. Ilɛksɛf wi gɛt akyu strɛs , strɛs we nɔ de dɔn , ɔ strɛs we kin mek wi fil bad, wi bɔdi kin pul kɔtisol. na dat mek dεn kin kכl am bak "strεs כmon."

Wetin na di ifɛkt we kɔtisol gɛt pan wi bɔdi?

Kɔtisol na ɔmon we de afɛkt ɔlmost ɔl di ɔgan dɛn na wi bɔdi ɛn i de kɔntrol bɔku impɔtant wok dɛn. Lɛ wi tek wan luk pan wetin i bi.

Fɔ kɔntrol aw yu de biev we yu strɛs

We yu no se denja ɔr de fred, yu bɔdi kin go na say we yu de "fayt ɔ rɔnawe," wantɛm wantɛm, nɔto so? Da tɛm de, ɔmon dɛn lɛk adrenaline kin kɔmɔt. Dɔn, fɔ mek yu kɔntinyu fɔ wach, kɔtisol kin bigin fɔ kɔmɔt. Dɔn bak, kɔtisol de ɛp fɔ pul glukɔs , ɔ shuga, na wi liva fɔ gi wi di ɛnaji we wi nid dis tɛm.

di mεtabolism εn di blכd shuga lεvεl

Mεtabolism na jכs di prכsεs we wi bכdi de yuz εnεji fכ liv, wok, εn wok. Kɔtisol de ɛp wit dis bay we i de kɔntrol aw wi bɔdi de yuz glukɔs fɔ gɛt ɛnaji.

Fɔ ɛgzampul:

• i de afekt wi pankrias, i de ridyus di prodakshכn fכ insulin εn i de mek di prodakshכn fכ glukagon bכku. Pan ɔl we insulin de ridyus di shuga na di blɔd, glukagon de mek di shuga go ɔp.
• I kin afɛkt bak di adipɔs tisu, liva, ɛn mɔsul na wi bɔdi, ɛn i kin kɔntrol aw wi de yuz glukɔs.

Fɔ stɔp di inflamɛns

Fɔ shɔt tɛm, kɔtisol kin mek wi gɛt mɔ pawa bay we i de ridyus di inflamɛns , we na fɔ swel ɛn rɛd na di bɔdi. Bɔt if di kɔtisol lɛvɛl de bɔku ɔltɛm, wi bɔdi kin yus to am. Dɔn di kɔmɔn tin kin apin. Inflameshɔn kin bɔku ɛn di imyun sistɛm kin wik.

Fɔ rigul di blɔd prɛshɔn

Dɛn nɔ ɔndastand gud gud wan yet aw kɔtisol de kɔntrol blɔd prɛshɔn. Bɔt dɛn dɔn si se if pɔsin gɛt bɔku kɔtisol, i kin mek i gɛt ay blɔd prɛshɔn, ɛn if i nɔ bɔku, i kin mek i blɔd prɛshɔn go dɔŋ.

I de ɛp fɔ kɔntrol di saykl we pɔsin kin slip ɛn wek

Nɔmal wan, di kɔtisol lɛvɛl kin smɔl we wi de slip na nɛt. I kin rich di mak jɔs bifo wi wek na mɔnin. Dis sho se kɔtisol gɛt big impak pan wi sirkadian ritm , ɔ slip-wek saykl.

Aw wi bɔdi de kɔntrol di kɔtisol lɛvɛl?

Wi bɔdi gɛt wan rili kɔmpleks sistɛm fɔ kɔntrol di kɔtisol lɛvɛl. di men rol dεm fכ dis na di haypothalamus εn di pituitary gland na wi bren de ple. dis tu de kכntro di prodyushכn fכ kכtisol we di adrenal gland dεm de mek.

Dis na aw i kin apin:

1. We di kɔtisol we de na yu blɔd go dɔŋ, di haypothalamus de pul wan ɔmon we dɛn kɔl CRH (corticotropin-releasing hormone) .
2. dis CRH כmon de gi signal fכ di pituitary gland fכ mek wan כmon we dεn kכl ACTH (adrenocorticotropic hormone) .
3. afta dat dis ACTH כmon de mek di adrenal gland dεm prodyuz kכtisol εn rilis am insay di bכdi.

So, fɔ mek di kɔtisol gɛt wɛlbɔdi, ɔl dɛn tri ɔgan ya—di haypothalamus, di pituitary gland, ɛn di adrenal gland dɛn—fɔ wok fayn fayn wan.

Wetin kin apin if di kɔtisol lɛvɛl go ɔp?

we di kכtisol lεvεl hכy fכ lכng tεm, wi kin kכl dat kכndish כn haypa kכtisolism . Dis kin apin wit wan sik wae dɛn kɔl Cushing’s syndrome .

Wetin na di tin dɛn we kin mek di kɔtisol bɔku?

• Yuz kɔtikosterɔyd mɛrɛsin fɔ lɔng tɛm (e.g., prɛdnisɔn, prɛdnisolon, dɛksametazɔn) insay ay dos.
• di tכmכro dεm we de prodyuz ACTH – dεn wan ya kin divεlכp mכst na di pituitary gland.
• sist dεm we de fכm na di adrenal gland dεm εn prodyuz εksyכs kכtisol.

Di sayn dɛn we de sho se pɔsin gɛt bɔku kɔtisol

Wae di kɔtisol lɛvɛl go ɔp, ɔr wae yu gɛt Cushing’s syndrome, yu kin gɛt sɔm kayn sik lɛk:

• Weight gain , mɔ na di fes ɛn bɛlɛ.
• fεt dεposit dεm na di bak bitwin di sכlda dεm (wan hכmp we lεk bכfalo hכmp).
• di apinεns fכ wayd, pepul strεch mak dεm na di bεlε.
• di mכ sul dεm we de wik na di כp an εn di tכŋ.
• Di shuga na yu blɔd we de go ɔp , we kin mek yu gɛt Tayp 2 dayabitis bɔku tɛm.
• Di ay blɔd prɛshɔn .
• di ia we dεn nכ want fכ gro pan uman dεm – wan kכndyushכn we dεn kכl hirsutism .
• di bon dεm we wik – כstioporosis εn fraksh כn kin apin.

Wetin kin apin if di kɔtisol lɛvɛl go dɔŋ?

We di kɔtisol lɛvɛl smɔl pas aw i kin bi, dɔktɔ dɛn kin kɔl am haypokɔtisolism , ɔ adrenal insufficiency . Tu men kayn dis de.

Wetin na di tin dɛn we kin mek pɔsin gɛt smɔl kɔtisol?

• Praymari adrenal insufficiency: Dis kin bi we wi yon imyun sistεm de atak di adrenal gland dεm. Dɛn kin kɔl dis bak sik we dɛn kɔl Addison .
• Sεkɔndari adrenal insufisɛns: Dis kin apin if di pituitary gland nɔ de wok fayn ( hypopituitarism ) ɔ if di pituitary tumor de.

Di simptom dɛm fɔ lɛ kɔtisol nɔ bɔku

We di kɔtisol lɛvɛl nɔ bɔku, yu kin gɛt sɔm sayn dɛn lɛk:

• Fɔ fil taya bad bad wan (taya).
• We yu nɔ bin want fɔ lɔs yu wet .
• I nɔ kin want fɔ it igen .
• Lɔw blɔd prɛshɔn .

Wetin a kin du fɔ ridyus di kɔtisol lɛvɛl?

If yu gɛt wan sik lɛk Cushing’s syndrome, yu kin nid mɛrɛsin fɔ mek yu kɔtisol lɛvɛl go dɔŋ. Dis kin gɛt fɔ du wit mɛrɛsin ɛn/ɔ ɔpreshɔn. Bɔt sɔm tin dɛn de we wi kin du fɔ ɛp fɔ kɔntrol wi kɔtisol lɛvɛl:

• Gɛt gud slip: Prɔblɛm lɛk we yu nɔ de slip ɛn we yu de wok na nɛt kin mek yu gɛt mɔ kɔtisol.
• Ɛksesaiz: We yu de du bɔdi wok ɔltɛm, dat kin mek yu slip fayn ɛn i kin mek yu nɔ strɛs.
• Praktis dip brith: fכ brith we wi de kכntrol de mek wi parasimpatik nεv sεstem – di sistεm we de mek wi bכdi kol εn kכntro “rεst εn daygεst”.
• Gladi, smayl: We yu smayl, di ɔmon dɛn we dɛn kɔl ɛndɔfin kin kɔmɔt ɛn di kɔtisol lɛvɛl kin go dɔŋ.
• Mek yu gɛt gud padi biznɛs wit mɔtalman: We yu gɛt prɔblɛm ɛn tɛnsi ɔltɛm, dat kin mek yu strɛs ɔltɛm.