Yu smɔl pikin gɛt dɛn sik ya? - Lɛ wi lan bɔt Embryonic Tumors

Yu pikin kin gɛt ed pen bɔku tɛm? Ɔ yu dɔn notis ɛni chenj we yu smɔl pikin de gro? Sɔntɛnde, dɛn tin ya kin bi nɔmal tin. Bɔt sɔntɛnde, sɔntin kin de biɛn dɛn we nid fɔ bisin bɔt am. Tide wi go tɔk bɔt wan sik we kin kam pan dɛn kayn pikin ya, bɔt wi nɔ yɛri bɔku bɔt am, ɛn i kin siriɔs smɔl. dat na di εmbrayo tכmכro dεm, כ `(Embryonal Tumors)`. Nɔ wɔri, wi go tɔk bɔt ɔltin na simpul we.

wetin na dεn εmbrayo tכmכro dεm ya? Mek wi ɔndastand gud gud wan?

Fɔ tɔk am simpul wan, embryonal tumor na bren tumor we de kɔmɔt frɔm sɛl dɛn we de gro kwik kwik wan. dis sεl dεm de kכmכt frכm sεl dεm we lεf frכm we di pikin bin de insay di bεlε, dat na di tεm we di εmbrayo de. dis εmbrayo sεl dεm we dεn kכl ``Embrayonik sεl dεm`` gεt wan rili imכtant wok we di pikin in bכdi de divεlכp. bכt sכmtεm, ivin afta dεn bכn di pikin, sכm pan dεn εmbrayo sεl dεm ya kin de na di bren. na dεn sεl dεm we de lεf de bigin fכ divεlכp to εmbrayo tכmכro.

Dɛn tumbu ya kin afɛkt pikin dɛn mɔ. Sɔm kin gɛt kansa, we min se dɛn kin denja (malignant). Ɔda wan dɛn nɔ gɛt kansa, we min se dɛn nɔ kin du bad (benign). Bɔku tɛm, dɛn kin divɛlɔp na di bren. sכmtεm dεn kin divεlכp bak along di spεnal kכd. Di tin we denja pas ɔl na dat dɛn tɔŋ ya kin skata tru di sɛribrospaynal fluid (CSF), we na di wata we de rawnd di bren ɛn spɛshal kɔd. De kayn wae de denja pasmak kin spre kwik kwik wan ɛn kin mek pɔrsin in layf de pan denja.

yu dכkta kin kכl dεn εmbrayo tכmכro dεm ya כ ``Embryomas.'' Trade, dεn bin kכl dεm ya ``Primitive Neuroectodermal Tumor (PNET)''.

Yu tink se kayn kansa de we de na di εmbrayo? Wetin na dɛn?

yes, dεn εmbrayo tכmכro dεm ya dεn sheb dεm bak to difrεn tכp dεm. di tכp we kכmכn pas כl dεn kכl am ``Mεdulloblastoma.`` dis de divεlכp insay wan pat we dεn kכl ``Sεribכl.`` dat na, na di bak, bכtכm pat pan yu pikin in bren.

כda kayn εmbrayo tכmכro dεm de we nכto ``Mεdulloblastoma''. Dɛn na:

• `(Atypical teratoid/rhabdoid tumor - AT/RT)`: dis de divεlכp bak na di sεribεl (bak pan di bren).
• `(Embryonal tumor wit multilayered rosettes - ETMRs)`: dis dεn kכl am `(C19MC-altered)` כ `(NOS - dεn nכ spεsifiket כda we)`. i de divεlכp na di `(Sεribrכm)` (dat na di big pat na di tכp εn fכnt pan di bren) εn di spεnal kכd.
• `(Medulloepithelioma)`: dis de divεlכp na di bren, spεnal kכd, εn nεv dεm we de ausayd di spεnal kכd. Dis na kansa wae de gro kwik kwik wan, wae de agresiv. Bɔku tɛm dɛn kin kam pan pikin dɛn we rili yɔŋ, ɛn di chans fɔ mek dɛn wɛl nɔ kin bɔku.
• sεntri nεv sεstem nyuroblastoma: dis de divεlכp insay di layεr dεm fכ di tisu dεm we de rawnd di bren εn di spεnal kכd εn insay di nεv tisu dεm na di sεribεl.
• `(Kribrifכm nyuroεpitεlial tכmכro)`:dis kin apin na di kכva dεm we fulכp wit wata (vεntrikul dεm) insay di bren.

Aw dɛn kansa ya kin bɔku? Udat kin gɛt dɛn mɔ?

כl di tכmכro dεm na di US, dεn εmbrayo tכmכro dεm ya de mek lεk 12% pan כl di bren tכmכro dεm na pikin dεm we ol 0 to 14. pan dεm, di tכp we wi bin tכk bכt fכs, ``Medulloblastoma``, na di wan we kכmכn pas כl - dat na, mכr dan 68% pan כl di εmbrayo tכmכro dεm. ``Atypical teratoid/rhabdoid tumors - AT/RT`` de akכnt fכ bכt 17%.

Dɛn kansa ya kin bɔku pan bebi ɛn smɔl pikin dɛn. Pan ɔl we dɛn kin apin to big pipul dɛn, dɛn nɔ kin apin so ɔltɛm. fכ egzampl, di tכp `(AT/RT)` de mכr pan bכy pikin dεm we nכ rich 3 ia. di tכp `(ETMRs)` de mכr kכmכn pan gyal pikin dεm we nכ rich 4 ia.

Wetin na di sayn dɛm fɔ fetal kansa? Chek fɔ si if yu pikin gɛt dɛn tin ya

Di sayn dɛm wae de sho se pɔrsin gɛt blɔd na di bren kin difrɛn frɔm wan pɔrsin to ɔda pɔrsin. Dɛn kin dipen pan di pikin in ej, di kayn tumbu, ɛn usay i de na di bren. Bɔt sɔm kɔmɔn sayn dɛn de we yu kin si:

• Ɛd we de at, mɔ na mɔnin.
• Nɔs ɛn vɔmit.
• Fɔ fil taya, taya, ɛn slip ɔltɛm.
• di we aw yu de si (e.g. blכr vishכn, dכbl vishכn).
• Di sik dɛn we kin mek pɔsin sik.

Imajin, yu smɔl pikin nɔ de rɔn rawnd ɛn ple lɛk aw i bin de ple, i de ɔltɛm se "Mama, mi ed de at," ɛn sɔntɛnde i kin vɔmit jɔs lɛk aw i wek na mɔnin. If dɛn tin ya kɔntinyu, yu fɔ rili go to dɔktɔ.

Dɛn kin si dɛn sayn ya bak pan bebi dɛn:

• Di ed kin big wit di ej.
• di bihayvya chenj (e.g., yu de kray ɔltɛm, yu kin vɛks, yu nɔ kin rɛst).
• Fɔ lɔs balans we yu de waka ɔ rɔn, lɛk fɔ lɔs kɔdineshɔn.
• If yu nɔ it fayn na sayn fɔ se yu nɔ de it fayn.
• Fɔ nɔ mit di divɛlɔpmɛnt maylston dɛm we fit fɔ di ej (e.g., nɔ sidɔm, tinap, ɔ tɔk).

Wetin mek dis kansa we de na di εmbrayo kin gɛt? Wetin na di kɔz?

Kansa kin apin we di sɛl dɛn gro ɛn sheb nɔmal wan, pas aw dɛn fɔ sheb. Bɔt di wan dɛn we de stɔdi bɔt dis stil nɔ shɔ wetin mek dɛn εmbrayo sɛl dɛn ya we lɛf kin tɔn wantɛm wantɛm to εmbrayo tכmכro.

Ɛnitin de we kin mek pɔsin gɛt dis kansa?

yes, sכm kכndyushכn dεm we yu kin gεt wit yu pikin kin mek yu pikin gεt wan kayn εmbrayo kεnsar we dεn kכl ``Mεdulloblastoma.'' dεn kayn kכndyushכn dεm ya na:

• `(Turkot sindrom)`
• `(Rubinstein-Taybi sindrom)`
• `(Gorlin sindrom)`
• `(Li-Fraumeni sindrom)`
• `(Fankɔni anemia)`

Dɛn tin ya nɔ kin apin so ɔltɛm, bɔt if pɔsin na yu famili gɛt dis sik, i impɔtant fɔ tɛl yu dɔktɔ.

Wetin na di prɔblɛm dɛn we kin apin we pɔsin gɛt kansa na di εmbrayo? Yu tink se i denja?

di kכmplikεshכn dεm we di εmbrayo kεnsar kin kam wit kin mek yu layf de pan denja sכmtεm. So, i rili impɔtant fɔ mek wi no bɔt dis. De men komplikashon wae yu kin si na:

• Hydrocephalus na wan sik we di bren de ful-ɔp wit wata ɛn prɛshɔn de go ɔp. Dis kin pwɛl di bren.
• Bren we dɔn pwɛl.
• Cognitive impairment - Dis min se di ebul fɔ tink ɛn lan kin afɛkt.
• di chenj dεm we de apin na di hכmon fכnshכn (Endocrinopathies).

Aw dɔktɔ dɛn kin no dis kayn kansa? (Diagnosis) .

If yu pikin gɛt ɛni wan pan di sayn dɛm we wi bin dɔn tɔk bɔt, ɔ if yu gɛt ɛnitin fɔ wɔri bɔt yu pikin in wɛlbɔdi, go to yu pikin in dɔktɔ wantɛm wantɛm. Dɔktɔ kin no if yu pikin gɛt kansa bay we i de chɛk yu pikin ɛn du di tɛst dɛn we i nid.

Di dɔktɔ go aks yu bɔt yu pikin in sik, in wɛlbɔdi istri, ɛn if ɛnibɔdi na yu famili dɔn gɛt dis kayn sik.

Di tɛst dɛm wae dɛn kin du fɔ kɔnfirm di sik kɔrɛkt wan na:

• Wan MRI skan we dɛn kin du.
• Wan `(CT)` skan.
• lכmba pankshכn na we dεn kin tek sכm sכm wata frכm di spayna. Dɛn kin yuz dis bak fɔ si if di kansa sɛl dɛn dɔn skata.
• fכ tek wan sכm sכm tisu frכm di tכmכro εn egzamin am (Biopsy). Dis na wetin de mek wi ebul fɔ no di rayt kayn kansa.

Wetin na di tritmɛnt fɔ dis? Yu tink se di pikin go wɛl?

Di tritmɛnt fɔ tɛstikul kansa kin difrɛn difrɛn wan bay bɔku tin dɛn, lɛk di kayn kansa, di sayz we di tumbu gɛt, ɛn usay i de. Di tritmɛnt dɛn we dɛn kin gɛt na:

• Ɔpreshɔn we dɛn kin du fɔ pul di tɔŋ na di ɔpreshɔn we dɛn kin du fɔ pul di tumbu.
• Redyushɔn tɛrapi.
• Gi mɛrɛsin dɛn we de agens kansa (Kɛmotɛrapi).
• Targeted Therapy (dεn ya na spεsifi k drog dεm).

Bɔku tɛm, yu pikin kin nid pas wan tritmɛnt. Fɔ ɛgzampul, dɔktɔ dɛn go pul di tumbu as sef as dɛn ebul wit ɔpreshɔn. Dɔn, dɛn kin gi dɛn kemotɛrapi fɔ kil ɛni kansa sɛl we lɛf ɔ fɔ mek di tumbu smɔl mɔ.

Dɛn de du mɔ risach bɔt dis kayn kansa we de na di εmbrayo, ɛn yu pikin kin ebul fɔ du klinik trial fɔ fɛn nyu tritmɛnt.

Na nɔmal tin fɔ fil strɛs ɛn pwɛl hat insay dis tɛm we yu de fil bad. Bɔku mama ɛn papa dɛn kin si se dɛn kin jɔyn sɔpɔt grup ɔ tɔk to pɔsin we de gi advays bɔt mental wɛlbɔdi biznɛs insay dis tranga tɛm. Di dɔktɔ ɛn nɔs dɛm we de trit yu pikin go tich yu bak aw fɔ sɔpɔt ɛn kɔrej yu pikin insay dis tɛm.

Ɛni bad tin de we di tritmɛnt kin du? Wetin na dɛn?

Yɛs, lɛk ɔl di tritmɛnt dɛn, sayd ɛfɛkt dɛn kin de.

Sɔm bad tin dɛn we kin apin afta dɛn dɔn du di ɔpreshɔn:

• Blɔd we de kɔmɔt.
• Blɔd we de klɔt.
• Sik we de prɛd.
• Nɛv dɛn we dɔn pwɛl.

Di sayd ɛfɛkt dɛn we pɔsin kin gɛt we i gɛt raytin ɛn kemotɛrapi na (bɔt nɔto jɔs):

• Taya.
• Nɔs ɛn vɔmit.
• Di ia we de lɔs.
• Skin alɛji, rɛdnɛs.
• Ed de at.

Sɔm kansa kin kam bak ivin afta dɛn dɔn trit am ɛn pul am.

Wetin na di prɔgnosis fɔ di sik?

Di kɔs fɔ yu pikin in sik, i.e. di chans fɔ mek i wɛl, dipen pan sɔm tin dɛm, lɛk:

• Tayp fɔ kansa.
• Usay di kansa de.
• Ilɛksɛf di kansa dɔn skata ɔ nɔ skata.
• Di pikin in ej.
• Di tin dɛn we kin kɔmɔt frɔm di ɔpreshɔn ɔ di tritmɛnt dɛn we dɛn bin dɔn du trade.
• Di pikin in jenɛral wɛlbɔdi.

Sɔm jεm sɛl tכmכro dεm kin rili agresiv, dεn kin spre izi wan, εn kin kam bak ivin afta dεn trit dεm. Ɔda wan dɛn kin bi benign. Yu pikin in dɔktɔ na di bɛst pɔsin fɔ tɛl yu bɔt di prɔgnosis.

Wetin wi kin se bɔt di pikin in layf we i de pan dis kayn tin?

I nɔ kin izi fɔ gi wan patikyula ansa bɔt aw pikin dɛn we gɛt dis sik kin liv, bikɔs i kin difrɛn. fכ egzampl, wan stכdi ripot se bכt 33% pan di pikin dεm we gεt Mεdulloblastoma de day fכ di kכmplikεshכn dεm. fכ mכr siriכs εmbrayo tכmכro dεm lεk ETMR dεm, di avεrej tεm we dεn de liv afta dεn no di sik na lεk 12 mכnt.

Bɔt di layf we yu pikin kin liv kin difrɛn frɔm ɔda pikin dɛn we gɛt di sem kayn kansa. I dipen pan tin dɛm lɛk di sayz fɔ di tumbu ɛn usay i de. Yu pikin in mɛdikal tim go gi yu di laytst infɔmeshɔn bɔt di tritmɛnt opshɔn dɛm ɛn di bɛst kia we yu de kia fɔ naw we go mek yu pikin in chans fɔ liv bɛtɛ.

Ustɛm a fɔ go to dɔktɔ?

If yu notis ɛni wan pan dɛn sayn ya fɔ fetal kansa na yu pikin , mek shɔ se yu go to dɔktɔ:

• If yu de mis di divɛlɔpmɛnt maylston dɛm we fit yu ej.
• If big chenj dɛn de na di we aw pɔsin de biev.
• If i nɔ izi fɔ yu fɔ it, if yu nɔ want fɔ it igen.
• If yu gɛt prɔblɛm wit balans we yu de waka ɔ rɔn.
• If yu kin fil nɔys ɔ vɔmit bɔku tɛm.

Di tin we impɔtant pas ɔl: If yu pikin gɛt sik we de mek i sik, kɔl 911 (ɔ yu lokal imejensi nɔmba) wantɛm wantɛm, ɔ kɛr dɛn go na di ɔspitul imejensi dipatmɛnt we de nia yu wantɛm wantɛm.

Wetin na di impɔtant kwɛstyɔn dɛn we wi fɔ aks di dɔktɔ?

Na tɛm lɛk dis, yu go gɛt bɔku kwɛstyɔn dɛn. Nɔr frayd fɔ aks yu dɔktɔ ɔltin wae de na yu maynd. Na sɔm impɔtant kwɛstyɔn dɛn we yu kin aks:

• Usay di tumbu de?
• Us kayn tritmɛnt yu kin advays?
• Wetin na di sayd ɛfɛkt dɛm we di tritmɛnt dɛm kin gɛt?
• Aw a go sɔpɔt mi pikin we a de du dis tritmɛnt?
• Wetin na di prɔgnosis (chans fɔ wɛl) fɔ mi pikin in sik?

Wan impɔtant mɛsej fɔ mama ɛn papa dɛn (Take-Home Message) .

I nɔmal fɔ mek yu fred, nɔ ebul fɔ du ɛnitin, ɛn wɔri we yu kam fɔ no se yu pikin gɛt wan tumbu we go mek i day. I kin tranga fɔ bia fɔ mek pikin gɛt ɔpreshɔn ɛn gɛt tranga tritmɛnt lɛk kemotɛrapi we i yɔŋ. Fɔ kɔrej pikin da kayn tɛm de kin rili at.

Bɔt mɛmba dis: Pan ɔl we dis kayn kansa nɔ kin bɔku, di dɔktɔ dɛn we de trit yu pikin gɛt bɔku trenin ɛn dɛn gɛt ɛkspiriɛns. Dɛn go du ɔl wetin dɛn ebul fɔ mek dɛn nɔ gɛt bɔku prɔblɛm ɛn di sayd ɛfɛkt dɛn we di tritmɛnt kin gɛt, ɛn fɔ gi yu pikin di kɔmfɔt ɛn kia we i nid insay dis tranga waka.

If yu nɔ shɔ wetin fɔ du ɔ aw fɔ ɛp yu pikin, tɔk to yu pikin in dɔktɔ dɛn. Dɛn kin ɛksplen to yu pikin in kɔndishɔn ɛn wetin go apin tumara bambay. Dɛn kin sho yu ɔda tin dɛn bak, lɛk fɔ tɔk to pɔsin we de gi advays bɔt yu maynd ɔ fɔ jɔyn sɔpɔt grup.

Insay dis tɛm, i go rili ɛp yu fɔ de rawnd yu padi ɛn fambul dɛn we yu kin abop pan ɛn we yu kin tɔk to.

` Embryo Tכmכro, Bren Tכmכro, Pikin Kεnsar, Kεnsar Simptom, Kεnsar Tritmεnt, Mεdulloblastoma