Wi ɔl no se blɔd de flɔ ɔlsay na wi bɔdi, nɔto so? Dis blɔd nɔ jɔs de flɔ tru wan nɛtwɔk we gɛt tiub dɛn we dɛn kɔl blɔd vesel, we tan lɛk wata paip. So yu dɔn ɛva wɔnda aw di insay pan dɛn tiub dɛn ya tan lɛk? Tide wi go tɔk bɔt wan wɔndaful, rili tin layt we gɛt sɛl dɛn we de layn insay dɛn tiub dɛn de. wi kכl dis di 'εndoteyl' . Dis nɔto jɔs layn, na wan sistɛm we gɛt smɔl smɔl sɛl dɛn we de du bɔku rili impɔtant wok dɛn we de afɛkt di wɛlbɔdi na yu wan ol bɔdi.
Fɔ tɔk am simpul wan, wetin na dis ɛndoteyl?
Imajin se ɔl di blɔd vesel dɛn na yu bɔdi gɛt wan tin we rili tan ɛn we smɔl, we na wan sɛl nɔmɔ tik, lɛk wan pikchɔ we dɛn mek na di wɔl. Dat na di ɛndoteyl. i mek wit wan spεshal tכp sεl we dεn kכl εndoteyl sεl dεm.
dis sem εndoteyl de fכn na dεn ples ya na yu bכdi:
- Atεri dεm: Na big big bכdi dεm we de kכri bכdi frכm di at to כda pat dεm na di bכdi.
- Vein: Na di blɔd vesel dɛm we de kɛr blɔd kɔmɔt na di bɔdi bak to di at.
- Kapilari: Na rili fayn, smɔl smɔl blɔd vesel dɛn.
- di limf kapilari dεm: Na di vεsεl dεm we de insay wi limf sistεm.
I nɔ jɔs bi wan wɔl. I de wok lɛk wan men say fɔ chenj infɔmeshɔn ɛn tin dɛn we de mek yu blɔd ɛn di ɔda pat dɛn na yu bɔdi. I so impɔtant, sayɛnsman dɛn naw de tek di ɛndoteyl as wan pan di big ɔgan dɛn na wi bɔdi. Yɛs, na ɔgan, jɔs lɛk di liva ɛn di at.
Us savis di εndoteyl de gi wi bɔdi?
Di wok we dis smɔl smɔl sɛl dɛn de du rili wɔndaful. Lɛ wi tek tɛm luk sɔm pan di men wan dɛn.
I de kɔntrol di kɔntrakshɔn ɛn dilayshɔn na di blɔd vesel dɛn
Yu blɔd vesel dɛn nid fɔ big (vasodilate) we nid de, ɛn smɔl (vasoconstrict) we nid de. dis na di εndoteyl de kכntro am.
Tink bɔt am dis we.
- We yu de du ɛksɛsayz: Yu mɔsul dɛn nid mɔ blɔd ɛn ɔksijɛn. di εndoteyl de sεnd signal fכ mek di blכd vesel dεm na da εria de big, we de mek di bכdi fכ fכlכ izi wan.
- Na de we rili kol: Yu want fɔ kip yu bɔdi wam. Dis kin mek di blɔd vesel dɛn na yu an ɛn yu fut dɛn kin kɔnstrikt smɔl, ɛn dis kin ɛp fɔ mek blɔd kɔntinyu fɔ flɔ to yu men ɔgan dɛn.
Dis we ya, i kin ɛp bɔku fɔ kɔntrol yu blɔd prɛshɔn ɛn mek shɔ se ɔl di ɔgan dɛn gɛt di blɔd we dɛn nid.
i de mεnεj di כmכnt fכ wata we de kכmכt na di bכdi to di tisu dεm
Di ɛndoteyl tan lɛk filta. i de mek di nyutriεnt dεm εn כksijεn we de kכmכt na di bכdi pas tru to di tisu dεm, εn i de wok bak lεk prכtektiv barεri we de mek bad tin dεm εn tכxin dεm nכ go insay di bכdi. Bɔt we yu gɛt infɛkshɔn, wi imyun sɛl dɛn nid fɔ kɔmɔt na di blɔd ɛn go usay di infekshɔn de. Dɔn di ɛndoteyl insɛf de klia di rod fɔ mek dɛn sɛl dɛn de go de.
I de mek blɔd nɔ klɔt (Thrombosis) .
Nɔmal wan, di blɔd we de klɔt insay di blɔd vesel dɛn kin rili denja, nɔto so? E kin mek yu gɛt siriɔs sik lɛk at atak ɛn strok. di εndoteyl we gεt hεlty de rilis spεshal kεmikכl dεm lεk naytrik oksayd, we de kip di bכdi fכ wata εn mek i nכ kכlכt we nכ nid fכ kכlכt.
Aw big di ɛndoteyl de? Usay i de na wi bɔdi?
If pɔsin aks yu usay yu at de, yu de sho yu chɛst. If pɔsin aks yu usay yu bren de, i de sho yu ed. Bɔt if pɔsin aks yu usay di ɛndoteyl de, yu kin pɔynt to ɛni pat na yu bɔdi. I so bɔku ɔlsay na di bɔdi.
Jɔs tink bɔt dat, if dɛn bin layt ɔl di blɔd vesel dɛn na di avɛrej pɔsin frɔm ɛnd to ɛnd, dɛn go lɔng lɛk 100,000 kilomita ! Dat na mɔ pas inof fɔ waka rawnd di wɔl tu tɛm. εn dis ol lεngth de kכba wit dis εndoteyl. If yu tek in eria, i kin big pas bɔku tɛnis kɔt dɛn. כlso, dis כl sistεm kכmכt fכ pas wan trilyכn (1,000,000,000,000) εndoteyl sεl dεm.
Wetin na di Endothelial Dysfunction?
Dis na di impɔtant pat we wi ɔl nid fɔ pe atɛnshɔn to. ‘Endothelial Dysfunction’ jכs min se di εndoteyl sεl dεm dεn dכn pwεl εn dεn nכ kin du dεn wok fayn fayn wan. I tan lɛk se di asfalt we de na rod dɔn kɔmɔt, ɛn dis dɔn mek i nɔ izi fɔ mek motoka dɛn drayv go.
Dis we aw di εndoteyl wik na di fכs tin we de mek di denja sik we dεn kכl atεrosklεrosis , we fεt de kכlכp na di at in wכl dεm εn blכk di blɔd vεsul dεm.
| di men enimi dεm we de damej di εndoteyl | Wetin kin apin to am? |
|---|---|
| Ay blɔd prɛshɔn (Hypertension) . | We blɔd de flɔ wit ay prɛshɔn, di ɛndoteyl sɛl dɛn kin pwɛl, jɔs lɛk aw wata we de rɔsh tru paip kin skrach di insay. |
| Ay kɔlɔstrel (Hyperlipidemia) . | εspεshali we "bad" kכlestכl (LDL) de inkrεs, i de bigin fכ stik pan dεn εndoteyl wכl dεm ya we dεn dכn pwεl. |
| Dayabitis (Dayabetes Mɛlitɔs) . | di ay shuga lεvεl we de fכ lכng tεm na di εndoteyl sεl dεm dεn de pwεl di εndoteyl sεl dεm dairekt wan. |
| Fɔ smok | Bɔku bɔku pɔyzin kemikal dɛn we de insay sigrɛt smok kin atak di ɛndoteyl ɛn i kin ambɔg di wok we i de du kpatakpata. |
| Nɔ ɛksesaiz ɛn fɔ fat | di inflameshn we de te na di bכdi we kכz fכ nכ de du fכshal aktiviti εn fכ fat de pwεl di εndoteyl. |
| Sivɛri Infɛkshɔn dɛn | Insay siriɔs infɛkshɔn lɛk COVID-19 ɛn kɔndishɔn lɛk sepsis, di ɛndoteyl kin pwɛl bad bad wan. |
wetin kin apin we di εndoteyl insεf wik?
we di εndoteyl dεm dכn pwεl, in smol sכft say kin rכf. Dɔn bad kɔlɔstrel (LDL) kin bigin fɔ gɛda na dɛn say dɛn de we rɔf. Fɔ ansa dis, di sɛl dɛn we de kɔmɔt na di bɔdi in imyun sistɛm kin kam ɛn gɛda de. כl dis de kכmכt, εn as tεm de go, i de fכm wan ‘fεt layεr’ (plak) .
As dis fat layt de gro, di blɔd vesel de smɔl frɔm insay. Dɔn dis kin mek blɔd nɔ flɔ. If wan de dis fat layt bɔs, blɔd kin klɔt na da say de ɛn blok di blɔd vesel kpatakpata.
So, pɔrsin wae gɛt wik ɛndoteyl kin gɛt dɛn kayn risk factor dɛm ya:
- At atak
- Strok
- Koronari at sik
- Di sik we de na di periferik at
- Kidni sik
- Insulin rɛsistɛns
So aw wi go kip dis εndoteyl hεlty?
Di gud nyus na dat wi kin protɛkt dis valyu ɛndoteyl bay we wi de chenj di we aw wi de liv wi layf.
Fɔ tɔk am simpul wan, wi bɔdi de mek wan kayn bad bad tin we dɛn kɔl ‘fri radikal’ . Dɛn tin ya kin pwɛl wi ɛndoteyl sɛl dɛn. di gud tin dεm we de εp fכ pul dεn bad bad tin ya dεn kכl dεm ‘antioxidants’ . So wetin wi nid fɔ du na fɔ ridyus di prodakshɔn fɔ fri radikal bay we wi de it it dɛn we gɛt bɔku antiɔksidant.
Gud tin dɛn fɔ du
It mɔ it dɛn we gɛt bɔku antiɔksidant.
- Dak grɛn vɛjitebul dɛn: spinach, kale, kɔla grɛn.
- Frut ɛn vɛjitebul dɛn we gɛt brayt kɔlɔ: tomato, karɔt, bit, bɛl pepa, ɔrɛnj, grepfruit.
- Wul grens: brawn rays, ɔts, ɛn malet.
- Ɔyl dɛn we gɛt wɛlbɔdi: ɔliv ɔyl, avokado.
Yu kin tɔk to yu dɔktɔ bɔt dis kayn it (e.g., di Mɛditarenian it) ɛn mek chenj dɛn we go fayn fɔ yu.
Bad tin dɛn we wi fɔ avɔyd
Dɛn tin ya kin mek di fri radikal dɛn na yu bɔdi bɔku.
- Smok: Dis na ɛnimi nɔmba wan. Kwɛt tide.
- Fɔd dɛn we gɛt bɔku shuga ɛn swit: Dɛn tin ya kin mek di bɔdi inflamɛns.
- Fɔd dɛn we dɛn dɔn prosɛs: Dɛn tin ya kin gɛt fat ɛn kemikal dɛn we kin ambɔg pɔsin.
- Stret we pasmak.
- Nɔ gɛt bɛtɛ slip.
Dɔn bak, ɛksɛsayz ɔltɛm rili impɔtant fɔ di ɛndoteyl wɛlbɔdi. We yu de du ɛksɛsayz, di naytrik ɔksayd we dɛn de mek kin bɔku, ɛn dis kin mek yu blɔd vesel dɛn gɛt wɛlbɔdi. Ivin sɔntin we simpul lɛk fɔ waka fɔ 30 minit ɛvride kin mek big difrɛns.
If yu dɔn gɛt wan sik lɛk ay blɔd prɛshɔn, dayabitis, ɔ kɔlɔstrel, i impɔtant fɔ fala yu dɔktɔ in tritmɛnt plan di rayt we . Di gol fɔ dɛn mɛrɛsin ya na fɔ kɔntrol dɛn tin ya ɛn fɔ mek yu ɛndoteyl nɔ pwɛl bɛtɛ.
Mɛsej we dɛn kin kɛr go na os
- di εndoteyl na wan imכtant layεr fכ sεl dεm we yu nכ de si, bכt i rili pawaful, we de layn insay yu bכdi vεsul dεm.
- di hεlth fכ yu at εn bכdi vεsul dεm dipכnt pan di hεlth fכ dis εndoteyl.
- Ay blɔd prɛshɔn, ay kɔlɔstrel, dayabitis, ɛn mɔ fɔ smok na di men ɛnimi dɛn fɔ dis.
- Yu kin protɛkt dis valyu ɔgan bay we yu it fayn it we gɛt fresh vɛjitebul ɛn frut, ɛn du ɛksɛsayz ɔltɛm.
- Yu fɔ no bɔt yu wɛlbɔdi biznɛs, go de chɛk yu ɔltɛm, ɛn if yu gɛt ɛni sik, go to yu dɔktɔ ɛn go to di rayt tritmɛnt.
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