Yu pikin gɛt bren tumbu lɛk dis? Mek wi no bɔt (Ganglioglioma)!

Yu smɔl pikin kin gɛt sik we de mek i sik wantɛm wantɛm? Ɔ i kin kɔmplen ɔltɛm se in ed kin at we i wek na mɔnin? Na nɔmal tin fɔ mek yu as mama ɔ papa fil bad bad wan we yu si tin dɛn lɛk dis. Sɔntɛnde, dɛn tin ya kin bi sayn fɔ wan smɔl tumbu na di bren. Na dat mek tide wi tink fɔ tɔk bɔt dis kayn bren tumbu we nɔ kin bɔku we dɛn kɔl Ganglioglioma . Nɔ wɔri, wi go tɔk bɔt dis ditayli ɛn simpul wan.

Wetin na dis Ganglioglioma?

Fɔ tɔk am simpul wan, Ganglioglioma na wan kayn tumbu we nɔ kin bɔku na di bren. i mek wit tu kayn sεl dεm we kכmbayn: nyuronal sεl dεm εn glial sεl dεm .

Tink bɔt am, wi bren tan lɛk mashin we rili kɔmpleks.

• di nyuronal sεl dεm lεk di waya dεm we de kכri infכmeshכn go εn go bifo na dis mashin. Dɛn sɛl ya de kɛr infɔmeshɔn go ɔlsay na wi bɔdi.
• Glial sel dεm lεk di sכpכt staf dεm we de εp fכ kip dεn waya dεm de insay. Dɛn kin mek di strɔkchɔ na wi sɛntral nervous system , ɛn dɛn kin wok togɛda wit nyuron dɛn fɔ ɛp dɛn fɔ wok.

dεn kכl di ganglioglioma dεm bak miks nyuronal-glial tכmכro biכs dεn de fכm frכm wan kכmbaynshכn fכ di tu kayn sεl dεm. Dɛn kin si dɛn mɔ pan pikin ɛn yɔŋ pipul dɛn .

Di gud nyus na dat bɔku tɛm, dɛn gangliogliomas ya kin smɔl, dɛn kin gro sloslo, ɛn dɛn nɔ kin gɛt kansa (benign) . Dis min se dɛn nɔ de skata to ɔda pat dɛn na di bɔdi. Bɔt ilɛksɛf dɛn nɔ gɛt kansa, dɛn kin mek prɔblɛm bikɔs dɛn de na di bren, so i nid fɔ gɛt tritmɛnt.

כl di ganglioglioma dεm dεn kin kכ l dεm lכw grεd gliomas . Gliomas na tכmכro dεm we de divεlכp na di bren כ spεnal kכd bikoz fכ di glial sεl dεm we nכ de kכntrol. Bikɔs dɛn nɔ gɛt bɔku kansa, dɛn nɔ kin gɛt kansa ɛn dɛn nɔ kin gɛt bɔku kansa bak.

Bɔt, na smɔl tɛm nɔmɔ, dɛn Gangliogliomas ya kin bi ay-grɛd . If na so i bi, dɛn kin bi malignant . Dɛn kin vɛks pasmak, dɛn kin skata kwik kwik wan, ɛn dɛn kin kam bak afta dɛn dɔn trit dɛn.

Difrɛn kayn gangliogliomas de? Usay dɛn kin fɔm?

Gangliogliomas kin de mɔ na di pat dɛn na yu bren nia yu yes, we dɛn kɔl di temporal lobes . Bɔt, dɛn kin divɛlɔp ɛnisay na di bren. Fɔ ɛgzampul:

• Sεribra - di big pat pan wi bren.
• Bren stεm - di εria we di bren εn di spεnal kכd de kכnekt.
• Sεribεl - di pat we de kכntro di bεlε.
• Thalamus we dɛn kɔl Thalamus
• Hypothalamus we dɛn kɔl haypothalamus

nכto dis nכmכ, sכmtεm dεn tכmכro dεm ya kin fכm bak na di spεnal kכd .

Wan ɔda kayn de we nɔ kin bɔku, we dɛn kɔl Desmoplastic Infantile Ganglioglioma . dis kin apin na di כp pat na di bren pan yכŋ pikin dεm we nכ rich 2 ia .

Aw dis sik kin bɔku?

Ganglioglioma na rili wan sik we nɔ kin apin so ɔltɛm. Fɔ ɛgzampul, na Amɛrika, ɛvri ia, na lɛk 4,000 pikin dɛn we nɔ rich 19 ia kin gɛt wan sik na dɛn bren ɔ spɛnal kɔd. Bɔt na lɛk 1% to 2% pan dɛn pikin dɛn de nɔmɔ gɛt ganglioglioma. So, dis nɔto so tin we nɔ kɔmɔn.

Wetin na di sayn dɛm fɔ dis?

As a bin dɔn tɔk bifo tɛm, bikɔs dɛn tumbu ya kin kam bɔku tɛm na di tɛmporal lobes, chans de fɔ mek pɔsin gɛt ɛpilepshi . So, sɔntɛm na di fɔs sayn we yu kin notis pan yu pikin we yu kin sidɔm .

Ɔda sayn dɛn kin kam smɔl smɔl. Dɛn sayn ya kin difrɛn difrɛn wan bay usay di tumbu de na di bren:

• Ɛd we de at , mɔ we yu de grap na mɔnin.
• Nɔs ɛn vɔmit .
• I nɔ izi fɔ swɛla .
• Dabl vishɔn .
• We yu nɔ de waka fayn .
• Fɔ fil taya (Fatigue) .
• Diziz we pɔsin kin gɛt .
• Wiknɛs na wan say na yu bɔdi .

If yu pikin gɛt wan ɔ mɔ pan dɛn sik ya, i go fayn fɔ mek yu go to dɔktɔ wantɛm wantɛm ɛn mek dɛn chɛk am.

Wetin mek dis Ganglioglioma kin kam?

Bɔrku tɛm, i nɔ kin izi fɔ fɛn wan patikyula kɔz fɔ di divɛlɔpmɛnt fɔ dɛn Gangliogliomas ya. Dis min se dɛn kin divɛlɔp ɔlmost randomly.

כltu, risechכr dεn fכnshכn se wan jεnεtik mכtεshכn na di BRAF jin de fכn bitwin 10% εn 60% pan dεn gangliogliomas ya. כltu, dεn kin fכn dis jεnεtik mכtεshכn bak insay כda kayn tכmכro dεm, so i nכ pכsibul fכ se fכ sכri se dis na spεshal kכz fכ gangliogliomas.

Wetin na de risk factor fɔ dis sik?

Pikin dεm we gεt sכ m jεnεtik kכndishכn dεm kin gεt sכm hεvi risk fכ gεt glial tכmכro, inklud ganglioglioma. Sɔm pan dɛn tin ya na:

• Nyurofibromatosis tayp 1 (NF1) .
• Tuberous sclerosis we gɛt di sik
• Turcot sindrom we gɛt di sik
• Li-Fraumeni sindrom we gɛt di sik
• Di sik we dɛn kɔl Von Hippel-Lindau

Apat frɔm dat, di data sho se bɔku tɛm bɔy pikin dɛn kin gɛt bren ɛn spɛshal tɔŋ pas gyal pikin dɛn, ɛn wayt pikin dɛn kin gɛt dɛn tumbu ya bɔku tɛm pas pikin dɛn we kɔmɔt na ɔda trayb.

Aw yu no dis klia wan?

If yu pikin gɛt dɛn sik ya, dɔktɔ go du fɔs fɔ chɛk in bɔdi gud gud wan . Dɔn dɛn go aks yu bɔt yu pikin in sik ɛn in mɛdikal istri.

Neks, dɛn kin du wan nyurolɔjik ɛgzam . dis de tεst di pikin in rεflεks, mכsul in trεnk, mכt εn yay muvmεnt, kכnsεns, εn kכdכnayshכn.

Afta dɛn fɔs tɛst ya, di dɔktɔ go tɛl yu fɔ du sɔm ɔda tɛst dɛn fɔ no if yu gɛt di sik:

• CT scan (Computed tomography - CT scan) : Dis de yuz wan siriכs X-ray εn kכmpyuta fכ tek kכros-sekshכnal imej dεm fכ di pikin in bren.
• MRI scan (Brain magnetic resonance imaging - MRI scan) : Dis de yuz pawaful magnet, redio wev, ɛn kɔmpyuta fɔ mek pikchɔ dɛn we rili ditayli bɔt di bren. Dis rili impɔtant fɔ no di rayt say ɛn di sayz we di tɔŋ de.
• EEG (Electroencephalogram - EEG) : dis tεst de mכsu di ilektrikal signal dεm εn di aktiviti fכ di pikin in bren. Dis kin ɛp fɔ no wetin mek yu gɛt sik, mɔ if na sik de mek yu gɛt sik.
• Bayopsi : Sɔntɛnde, i kin dipen pan di pikin in kɔndishɔn, nyurosɔjɔn kin du bayɔpsi. Dis min se dɛn kin pul wan rili smɔl tisu na di tumbu, ilɛksɛf na ɔpreshɔn ɔ tru smɔl say we dɛn kɔt am, ɛn mek wan dɔktɔ we de stɔdi bɔt sik dɛn chɛk am ɔnda maykroskɔp . apat frכm dat, dεn kin sεnd dis tisu sεmpl fכ כda spεshal tεst dεm, lεk jεnomik tεst . Dis kin ɛp fɔ no di rayt kayn tumbu.

Aw dɛn kin trit Ganglioglioma?

Fɔ mek shɔ se yu pikin gɛt di bɛst tritmɛnt, i go fayn fɔ mek yu sɛn am to wan say usay dɛn de mɛn pikin dɛn . Yu fɔ go to wan dɔktɔ we gɛt di bɔd we gɛt sɛtifiket fɔ pikin dɛn we gɛt kansa ɔ pikin dɛn we gɛt ɛkspiriɛns fɔ trit gangliogliomas.

Di tritmɛnt we dɛn kin gi di pikin kin dipen pan bɔku tin dɛn:

• Di pikin in ɔl in wɛlbɔdi, in ej, ɛn di mɛrɛsin kɔndishɔn dɛn we i bin dɔn gɛt bifo.
• Di kayn tumbu, usay i de na di bren, ɛn di sayz we i gɛt.
• Di kayn we aw di tumbu kin siriɔs.
• Aw di pikin kin ebul fɔ bia wit sɔm tritmɛnt dɛn, ɔpreshɔn, ɔ mɛrɛsin dɛn.
• Aw di tumbu go go bifo lɛk aw di dɔktɔ dɛn de ɛkspɛkt.

Di fɔs layn fɔ tritmɛnt na ɔpreshɔn fɔ pul di tumbu. Di dɔktɔ go tray fɔ pul bɔku pan di tumbu as i ebul. Bɔt sɔntɛnde if di tumbu de na wan pat na di bren we rili sɛnsitiv, i kin at fɔ pul am kɔmɔt kpatakpata.

Imajin, if dɛn nɔ ebul fɔ pul di tumbu kpatakpata, ɛn if i ay, dɔktɔ dɛn kin yuz redyushɔn tɛrapi nɛks .

• Radiation therapy : Dis kin yuz X-ray we gɛt bɔku ɛnaji ɔ ɔda kayn raytin fɔ kil di kansa sɛl dɛn ɔ stɔp dɛn fɔ gro ɔ sheb. Dis tritmɛnt kin tɔch di rayt say we di tɔŋ de ɛn gi raytin. Dɛn kin advays dis tritmɛnt if di tɔŋ de gro sloslo (we de go bifo) ɔ if i dɔn kam bak afta dɛn du di ɔpreshɔn (we de kam bak).
• Kimotɛrapi : Dis kin min fɔ gi mɛrɛsin tritmɛnt dɛn we de kil ɔ shrink di kansa sɛl dɛn.
• Targeted therapy : Dis na tritmɛnt bak wit drɔgs. Bɔt dis kin yuz drɔgs we de tɔch wan patikyula mak nɔmɔ na di tɔŋ. bכku ganglioglioma dεm gεt spεshal mak dεm, lεk di BRAF jin mכtεshכn we wi bin tכk bכt bifo. Dɛn tritmɛnt ya we dɛn kin yuz fɔ mɛn pipul dɛn kin pwɛl dɛn mak dɛn de.

Sɔntɛnde, dɔktɔ dɛn kin se dɛn fɔ kɛr pikin dɛn we gɛt tumbu we de kam bak ɛn we nɔ de du ɔda tritmɛnt dɛn, go na klinik trial , we na stɔdi dɛn we de tɛst nyu tritmɛnt dɛn.

Wetin na di prɔgnosis?

Dis na wetin bɔku mama ɛn papa dɛn want fɔ no. di כvala fayv ia rεt fכ pikin we gεt ganglioglioma de pas 90% . Dis min se di pikin gɛt rili gud chans fɔ liv fayv ia afta dɛn dɔn no se i gɛt di sik.

Bɔt dis chans fɔ mek i wɛl kin dipen pan bɔku tin dɛn lɛk di gred we di pikin gɛt, di ej we di pikin ol, ɛn usay di tumbu de na di bren.

Chans de fɔ mek i gɛt di sik bak? (Rɛlaps) .

mכr dan 95% pan di ganglioglioma dεm na lכw grεd , we min se i nכ go izi fכ kam bak afta dεn dכn pul di tכmכro kכmplit wan.

Bɔt di tɔŋ dɛn we gɛt ay gred, lɛk gred 3 Ganglioglioma, gɛt smɔl chans fɔ kam bak afta dɛn dɔn du di ɔpreshɔn.

Yu tink se dɛn go ebul fɔ mek dis nɔ apin?

Bɔt i sɔri fɔ no se di wan dɛn we de stɔdi bɔt dis stil nɔ no bɛtɛ bɛtɛ wan wetin mek sɔm pikin dɛn kin gɛt Gangliogliomas ɛn ɔda wan dɛn nɔ kin gɛt am. So, naw, no we nɔr de fɔ mek dis sik nɔr kam..

Ustɛm a fɔ kɛr mi pikin go to dɔktɔ ?

If yu pikin gɛt sik we dɛn kɔl seizure wantɛm wantɛm, ɔ if dɛn de sho wan ɔ mɔ pan di ɔda sayn dɛn we a bin dɔn tɔk bɔt na dis atikul (lɛk we i de ed pen na mɔnin, i nɔ de fil fayn, i nɔ izi fɔ waka), i rili impɔtant fɔ kɛr yu pikin go to dɔktɔ wantɛm wantɛm fɔ mek dɛn chɛk am .

De sayn dɛm fɔ Ganglioglioma kin tan lɛk ɔda wɛl bɔdi sik dɛm, so i impɔtant fɔ go to dɔktɔ fɔ mek dɛn no di sik fayn fayn wan fɔ no gud gud wan wetin de apin.

Us kwɛstyɔn dɛn yu fɔ aks di dɔktɔ?

We yu kam fɔ no se yu pikin gɛt ganglioglioma, i nɔmal fɔ gɛt bɔku kwɛstyɔn dɛn na yu maynd. Na sɔm kwɛstyɔn dɛn we yu kin aks di dɔktɔ:

• Us kayn Ganglioglioma mi pikin gɛt?
• Yu tink se i gɛt kansa?
• Aw dis tumbu go afɛkt mi pikin in bren ɛn in wɛlbɔdi?
• Wetin na di tritmɛnt dɛn we yu kin gɛt?
• Yu kin rεkomεnd sɔpɔt grup dɛm wae de ɛp famili dɛm fɔ pikin dɛm wae gɛt ganglioglioma?

Fɔ dɔn, tin dɛn fɔ mɛmba...

"Yu pikin gɛt bren tumbu." We yu yɛri dɛn wɔd dɛn de, yu kin fil lɛk se yu dɔn frɔz fɔ smɔl tɛm. Insay wan tɛm we yu kin sɔprayz, yu layf kin fil lɛk se i dɔn chenj sote go.

Bɔt, nɔ giv ɔp fɔ op. Pan ɔl we dɛn wɔd ya kin mek pɔsin sɔprayz ɛn mek pɔsin fred, mɛmba se bɔku pan di gangliogliomas nɔto kansa, ɛn dɛn nɔ kin gɛt bɔku bɔku bɔdi.

Na nɔmal tin fɔ mek yu fred we dɛn tɛl yu pikin se i gɛt tumbu, ɛn i rili nid fɔ gɛt tritmɛnt. Bɔt yu pikin go ebul fɔ pul di tumbu jisnɔ . Tɔk to yu pikin in dɔktɔ bɔt in kɔndishɔn ɛn di prɔgnosis. Dɛn go gi yu ɔl di tin dɛn we yu nid.

` Ganglioglioma, bren tumor, pikin, sik, epilepsy, bren ɔpreshɔn, kansa