Yu dɔktɔ dɔn gi yu ɔ pɔsin we yu sabi wan pill we dɛn kɔl Guanidine? Yu kin want fɔ no smɔl, ɔ ivin fred smɔl, we yu yɛri dis nem. Bikɔs dis nɔto mɛrɛsin we wi kin yɛri bɔt bɔku tɛm. Guanidine na wan mɛrɛsin wae dɛn kin yuse fɔ trit wan kayn mɛrɛsin wae rili spɛshal ɛn wae nɔr kin bɔrku. So, i rili impɔtant fɔ mek wi no bɔt dis. So, tide wi go tɔk bɔt dɛn Guanidine pils ya, di mɛrɛsin we dɛn kin trit, aw fɔ yuz dɛn, ɛn di tin dɛn we wi fɔ tek tɛm wit.
Wetin na Guanidine ɛn us sik i kin trit?
Fɔ tɔk am simpul wan, Guanidine na drɔg we de mek di nerv dɛn wok ɛn mek di mɔsul dɛn wok fayn. fכ mεdikal, i de pan di klas כf drog dεm we dεn kכl `cholinergic muscle stimulants`.
Dɛn kin yuz dis mɛrɛsin mɔ fɔ trit wan sik we nɔ kin apin so ɔltɛm we dɛn kɔl Lambert-Eaton Myasthenic Syndrome (LEMS) .
Mek wi ɔndastand smɔl bɔt wetin na LEMS.
Imajin, di mɛsej dɛn we de kɔmɔt na di bren de kɔntrol di we aw wi bɔdi de muv. we dεn mεsej ya de travul tru di nεv dεm εn rich di mכsul dεm, wi kin ebul fכ muv wi an εn leg dεm εn waka. na di say we wan nεv εn wan mכsul mit, wan kεmikכl we dεn kכl `Acetylcholine` de kכmכt frכm di nεv εnd dεm. We dis kemikal rich di mɔsul, di mɔsul kin kɔntrakt, dat min se i kin wok.
Bɔt pan pɔsin we gɛt LEMS, di bɔdi in imyun sistɛm kin mistek atak dɛn nɛv ɛnd dɛn de. as a rizulכt, di amoun fכ `Acetylcholine` we dεn nid nכ de kכmכt. di rizulyt na we di mכsul dεm nכ de gεt di mεsej fayn fayn wan kin wik εn taya bad bad wan. We di mɔsul dɛn wik kin apin mɔ na di leg ɛn di hip dɛn.
Guanidine de wok bay we i de mek di kεmikכl mεsenja (Acetylcholine) kכmכt frכm di nεv εnd dεm. dis min se i de gi bכst to di blכk mεsej fכ fכlכ εn i de εp di mכsul dεm fכ wok fayn bak.
Tin dɛm wae yu fɔ tɛl yu dɔktɔ bifo yu bigin fɔ tek mɛrɛsin
Guanidine na drɔg we yu fɔ tek tɛm yuz. So, i rili impɔtant fɔ tɛl yu dɔktɔ bɔt yu kɔmplit mɛdikal istri bifo yu gi yu dis mɛrɛsin. Mek shɔ se yu tɛl dɛn if yu gɛt ɛni wan pan dɛn tin ya:
- Kidni sik: Yu fɔ tɛl yu dɔktɔ if yu gɛt ɛni sik we gɛt fɔ du wit kidni, bikɔs di kidni dɛn de ple big pat fɔ pul dis mɛrɛsin kɔmɔt na di bɔdi.
- Liva sik: If ɛni wikɛd tin de pan di liva wok, tɔk bɔt am bak.
- Blɔd sɛl prɔblɛm: If dɛn dɔn ripɔt se yu gɛt smɔl wayt blɔd sɛl, rɛd blɔd sɛl, ɔ pletlɛt na yu blɔd, dat na rili impɔtant infɔmeshɔn.
- Mental Illness: If dɛn de trit yu ɔ yu gɛt ɛni mental sik, duya tɛl wi.
- Alɛji: If yu gɛt alɛji fɔ guanidine ɔ ɛni ɔda mɛrɛsin, it, ɔ day.
- Bɛlɛ ɔ we yu de op fɔ bɔn pikin: If yu gɛt bɛlɛ ɔ yu de plan fɔ gɛt bɛlɛ, dis na sɔntin we yu fɔ tɔk bɔt.
- Fɔ gi pikin in bɛlɛ: Tɛl di dɔktɔ bak if yu na mama we de gi pikin in bɛlɛ.
Aw a fɔ yuz dis mɛrɛsin?
Di tin we impɔtant pas ɔl we yu de yuz dis mɛrɛsin na fɔ fala yu dɔktɔ in instrɔkshɔn dɛn gud gud wan.
- Swɛla dis pil wit wan glas wata.
- Yuz di mɛrɛsin jɔs lɛk aw dɛn rayt am na di prɛskrishɔn lɛbl. Nɔ tek mɔ ɔ smɔl pas di mɔni we yu dɔktɔ tɛl yu fɔ tek.
- Yu kin tek dis bifo ɔ afta yu it. Bɔt if yu bɛlɛ at, if yu tek am wit it, dat kin ɛp fɔ ridyus am.
- Gɛt di abit fɔ tek yu mɛrɛsin di sem tɛm ɛvride, di rayt tɛm.
- Di tin we impɔtant pas ɔl: Nɔ stɔp fɔ tek yu mɛrɛsin fɔ ɛni rizin if yu dɔktɔ nɔ advays yu. If yu stɔp wantɛm wantɛm, dat kin mek yu sik kam bak ɛn wɔs.
- If dɛn gi am to pikin dɛn: We dɛn de gi dis mɛrɛsin to pikin dɛn, i impɔtant fɔ go to dɔktɔ we de mɛn pikin dɛn.
Wetin a go du if a tek bɔku mɛrɛsin? (Ovados) .
If yu tink se yu kin aksidɛntli tek mɔ mɛrɛsin pas aw yu tink, nɔ delay. Wantɛm wantɛm, kɔl di Nashɔnal Pɔyzin Infɔmeshɔn Sɛnta na di Kɔlɔmbɔ Nashɔnal Ospital , ɔ go na di Imejɛnsi Tritmɛnt Yunit (ETU) na di ɔspitul we de nia yu.
Lɛ wi lan bak bɔt di sayd ɛfɛkt dɛm ɛn di intarakshɔn dɛm.
Lɛk ɛni mɛrɛsin, Guanidine kin mek yu gɛt sayd ɛfɛkt. I kin miks bak wit ɔda mɛrɛsin dɛn.
Sɔm sayd ɛfɛkt dɛn we pɔsin kin gɛt
Sɔm pan dɛn tin ya kin siriɔs, sɔm kin kɔmɔn. I impɔtant fɔ no bɔt dɛn tin ya.
| Tayp fɔ di sayd ɛfɛkt | Karakta |
|---|---|
| Siriɔs sayd ɛfɛkt dɛn we nid fɔ go to dɔktɔ wantɛm wantɛm | |
| Alɛji we pɔsin kin gɛt | Skin iritashɔn, it, swel |
| I nɔ izi fɔ blo | I nɔ kin izi fɔ yu fɔ blo |
| Di chenj dɛn we de apin na di at rit | At bit fast ɔ i nɔ de bit ɔltɛm |
| Sayn dɛn we de sho se pɔsin gɛt di sik | Fiva, trot we de at |
| Di chenj dɛn we pɔsin kin gɛt na in maynd | Fɔ si ɔ yɛri tin dɛn we nɔto rial (Hallucinations) . |
| Prɔblɛm dɛn we pɔsin kin gɛt we i de pis | I nɔ izi fɔ yu fɔ pis ɔ chenj di kayn pis we yu de mek |
| Wiknɛs we nɔ kɔmɔn | Fɔ fil se yu taya pasmak ɛn yu bɔdi wik |
| Di tin dɛn we kin apin to di liva | Yu yay ɔ yu skin kin yɔlɔ (lɛk janda) . |
| Kɔmɔn sayd ɛfɛkt dɛm we dɛn fɔ ripɔt to di dɔktɔ if dɛn kɔntinyu fɔ de | |
| Jɛnɛral kwaliti dɛn | Mɔt we de dray, diziz, ed we de at, bɛlɛ we de at, nɔs/vɔmit, dayarɛa, we yu nɔ want fɔ it |
| Ifekt pan di nervous system | Nɔmb, tingling, ɔ pen na di limb dɛm, di mud kin chenj |
Ɔda drɔgs dɛn we de intarakt wit Guanidine (Drug Interactions) .
Ɔda mɛrɛsin dɛn we yu de tek kin afɛkt di we aw Guanidine de wok. So tɛl yu dɔktɔ bɔt ɔl di mɛrɛsin dɛn we yu de tek (inklud vaytamɛn ɛn ɛbul prɔdak dɛm), mɔ if yu de tek ɛni wan pan dɛn tin ya:
- Sɔm mɛrɛsin dɛn we dɛn kin tek fɔ kansa
- Mεdikeshכn dεm we dεn gi fכ kכntrכl imyuniti afta dεn transplant כgan
- Sɔm mɛrɛsin fɔ mek yu gɛt sik (e.g., `Carbamazepine`) .
- Mεdikeshכn fכ mental sik lεk ``Clozapine''.
- Fɛnotiazin dɛn (e.g. Klɔrpromazin) .
- Steroid-tayp mεdikeshכn dεm (e.g. `Prednisone`, `Cortisone`) .
- `Sulfinpirazɔn`
Yu fɔ mɛmba se dis list nɔ kɔmplit, so fɔ mek yu sef, i bɛtɛ fɔ tɛl yu dɔktɔ bɔt ɔltin we yu de tek.
Mɛsej we dɛn kin kɛr go na os
- Guanidine na wan mɛrɛsin we dɛn kin yuz fɔ trit wan sik we nɔ kin apin so ɔltɛm, we dɛn kɔl Lambert-Eaton Myasthenic Syndrome (LEMS).
- Mek shɔ se yu tɛl yu dɔktɔ bɔt ɔl di mɛrɛsin dɛn we yu de tek, mɔ if yu gɛt prɔblɛm wit yu kidni, liva, ɔ blɔd.
- Yu nɔ fɔ ɛva bigin, stɔp, ɔ chenj di doz fɔ di mɛrɛsin if yu dɔktɔ nɔ advays yu.
- If yu gɛt ɛni siriɔs sayd ɛfɛkt lɛk fɔ mek yu nɔ ebul fɔ blo fayn, yu at de chenj, yu yay de yɔlɔ, ɔ yu gɛt fiva, go to dɔktɔ wantɛm wantɛm.
- If yu tink se yu dɔn tek di mɛrɛsin pasmak, go na di Nashɔnal Pɔyzin Infɔmeshɔn Sɛnta ɔ di ɔspitul in Imejɛnsi Dipatmɛnt (ETU) wantɛm wantɛm.
- Stɔr di mɛrɛsin na say we sef we di rum tɛmpracha, usay pikin dɛn nɔ go ebul fɔ rich.
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