Yu tink se dɛn kin rijek at afta dɛn dɔn transplant am? (Heart Transplant Rejection) Lɛ wi tɔk bɔt dis!

Yu si, fɔ gɛt nyu at tan lɛk fɔ bigin nyu layf. Dis na big rilif, mɔ fɔ pɔsin we in at wok dɔn rili wik, dat na, we in at nɔ de wok fayn . Bɔt sɔmtɛm wi bɔdi kin si dis nyu at lɛk "strenja" ɛn bigin fɔ riak agens am. Na dat wi kin kɔl Hat Transplant Rejection . Pan ɔl we dis kin mek yu fred smɔl, if yu tɛl yu bɔt dis fayn fayn wan, dat kin mek yu nɔ gɛt bɔku prɔblɛm dɛn. So lɛ wi tɔk bɔt dis ditayli tide, nɔto so?

Wetin rili na Hat Transplant Rijɛkt?

Fɔ tɔk am simpul wan, at transplant na ɔpreshɔn we dɛn kin pul at we gɛt siriɔs kɔndishɔn ɛn transplant at we gɛt wɛlbɔdi frɔm pɔsin we dɔn day. So, we yu bɔdi in imyun sistɛm no di nyu at as "nɔto yu yon, bɔt ɔda pɔsin in yon," i kin bigin fɔ atak di nyu at lɛk se i de fɛt sik. Na dat na rijekshon .

Dis kin apin mɔ insay di fɔs wik afta dɛn put am insay di bɔdi. Bɔt sɔntɛnde dis sik kin apin sɔm mɔnt ɔ ivin sɔm ia afta dat.

Di tin we impɔtant pas ɔl na dat bifo dɛn transplant yu at, dɔktɔ dɛn go bigin fɔ tek mɛrɛsin dɛn we de mek yu nɔ ebul fɔ fɛt yu bɔdi . Dɛn mɛrɛsin ya kin tray fɔ stɔp yu bɔdi in imyun sistɛm ɛn stɔp am fɔ atak di nyu at. Bɔt sɔntɛnde ivin wit dɛn mɛrɛsin ya, dɛn nɔ kin ebul fɔ stɔp fɔ rijek am kpatakpata.

If pɔsin nɔ gri fɔ tek am, dat kin mek i gɛt bɔku prɔblɛm dɛn. Fɔ ɛgzampul:

• At ritm irɛgyulariti (Arrhythmia): Dis kin mek pɔsin day wantɛm wantɛm.
• Di nyu at we nɔ de wok fayn.
• Fɔ gɛt at atak.

Wetin na di men kayn we dɛn we dɛn nɔ gri wit?

Tri men kayn rijekshכn de we dεn kin si pan hat transplant:

1. Akyu sεl rεjεkshכn: dis kin apin we wan spεshal kayn sεl na yu imyun sistεm we dεn kכl T sεl dεm de atak di nyu at sεl dεm. Dis kin apin mɔs insay di fɔs tri to siks mɔnt afta di transplant.

2. Krכnik rijekshכn: dis kin kכz fכ di imyun sistεm we de kכntinyu fכ atak di graft ova tεm. Bɔku tɛm, di men blɔd vesel dɛn we de gi blɔd to di at, we na di korona at, kin tik smɔl smɔl. Dis kin mek di ɔksijɛn ɛn di tin dɛn we di at nid nɔ bɔku.

3. Humoral rijekshכn: dεn kכl dis akyu antibodi rijekshכn.Dɛn kin kɔl am bak. Dis kin apin ɛni tɛm afta di transplant. Wetin kin apin ya na dat di antibodi dɛm we yu imyun sistɛm de mek kin pwɛl di blɔd vesel dɛm na di nyu at. Dɔn di at nɔ kin gɛt inof blɔd flɔ.

Aw kɔmɔn dis we aw pɔsin nɔ de gri fɔ tek in at?

Infakt, dis rijekshɔn na sɔntin we pɔsin kin si to sɔm mak pan pipul dɛn we dɔn gɛt at transplant. Dis kin apin sɔmtɛm ivin if dɛn tek di mɛrɛsin dɛn we de mek dɛn nɔ gɛt di sik kɔrɛkt wan. Bɔt di gud nyus na dat, we di mɛdikal sayɛns de go bifo, mɔ we dɛn de fɛn nyu tin dɛn bɔt di imyun supreshɔn , di risk fɔ mek dɛn nɔ gri fɔ tek dis sik de go dɔŋ smɔl smɔl.

Us tin dɛn kin mek pɔsin in at nɔ gri fɔ tek pat?

Sɔm tin dɛn de we kin mek pɔsin nɔ gri fɔ tek am. Lɛ wi si wetin dɛn bi:

• Sɔm wɛlbɔdi prɔblɛm dɛn we pɔsin we gɛt at gɛt: Fɔ ɛgzampul , i gɛt bɔku kɔlɔstrel , i nɔ kin ebul fɔ tek insulin , ɛn i kin gɛt ay blɔd prɛshɔn .
• Jɛnɛtik mismatch bitwin di pɔsin we gi am ɛn di pɔsin we de gi am.
• If di pɔsin we gi di at bin gɛt at sik.
• If sɔntin apin to di at we dɛn de pul am na di bɔdi, briŋ am kam bak, ɛn transplant am to nyu pɔsin.
• Di pɔsin we de gɛt di at na blak (dis na sɔntin we dɛn dɔn si na stɔdi, i nɔ kɔmɔn fɔ ɔlman).
• If di pɔsin we de tek di at yɔŋ pas di pɔsin we de gi di at.
• Immunosuppressive mɛrɛsin dɛn we dɛn nɔ de tek di kɔrɛkt doz, di kɔrɛkt tɛm, ɔ we nɔ de wok fayn wit ɔda nyu mɛrɛsin.

Wetin kin mek at nɔ gri?

dis kin apin biכs di imyun sistεm na yu bכdi de no di nyu hat as "fכrin tin." afta dat i de sεnd T sεl dεm, כ antibodi dεm , fכ atak di "invader."

Dis kin apin pan ɔl we dɛn kin gi di wan dɛn we gɛt at transplant di mɛrɛsin dɛn we de mek dɛn nɔ gri fɔ tek dɛn at. Sayɛnsman dɛn stil nɔ ɔndastand gud gud wan wetin mek dis kin apin.

Wetin na di sayn dɛm wae de sho se yu at nɔr de gri?

Dis na di pat we kin mek pɔsin kɔnfyus pas ɔl. Sɔntɛnde, at kin pwɛl ɛn nɔr kin gɛt ɛni sayn! Na dat mek dɔktɔ dɛn kin kɔntinyu fɔ tɛst yu, fɔ si if ɛnitin nɔ rayt. Bɔt sɔm pipul dɛn kin gɛt sɔm sayn dɛn.

Di kɔmɔn sayn dɛm fɔ fiva na:

• Pɔsin we de fil pen na di bɛlɛ.
• Bɔdi pen.
• Chills we de mek pɔsin kol.
• Rili taya (Fatigue).
• Low fiva, lɛk se di bɔdi dɔn wam pasmak.
• Nɔs ɔ nɔ want fɔ it.
• Fɔ fil se i nɔ fayn.

Ɔda sayn dɛn kin de bak:

• Diziz ɔ fɔdɔm.
• At palpitations , at bit kwik ɔ we nɔ de bit ɔltɛm.
• Les dan nכmal urine autput (Oliguria) .
• Lɔw blɔd prɛshɔn (Hypotension) .
• I nɔ izi fɔ blo (Dyspnea) .
• Wantɛm wantɛm, we yu nɔ bin de ɛkspɛkt fɔ gɛt mɔ wet.
• Di anklɛ, an, ɔ fut kin swel.

If yu si ɛni wan pan dɛn sayn ya, yu fɔ tɛl yu dɔktɔ wantɛm wantɛm, ɛn yu nɔ fɔ wet fɔ yu nɛks apɔntinmɛnt.

Aw yu kin no se pɔsin in at nɔ want?

Afta yu dɔn transplant yu at, yu go gɛt tɛst ɔltɛm fɔ chɛk if yu nɔ gri fɔ tek yu at. Yu dɔktɔ dɛn kin ɔda fɔ du tɛst lɛk:

• Blɔd tɛst fɔ chɛk fɔ DNA mak dɛn we gɛt fɔ du wit rijɛkt.
• Echocardiogram (lɛk ɔltra saund skan fɔ di at).
• Ilektrokardiogram (ECG ɔ EKG) tɛst (we de chɛk di ilɛktrik aktiviti na di at).
• Nyuklia kadyak strɛs tɛst .
• Angiography ( na wan X-ray we de luk di blɔd vesel dɛm na di at).
• Intravaskul ɔltrasɔund .
• Mayokardial bayɔpsi ɔ at bayɔpsi: Dis kin min fɔ tek wan rili smɔl pat pan di at ɛn chɛk am ɔnda maykroskɔp fɔ si sayn dɛn we de sho se i nɔ gri fɔ tek am. Dis na di bɛst we fɔ kɔnfirm se dɛn nɔ gri fɔ tek am.

Wetin fɔ du if pɔsin in at nɔ gri fɔ du am?

Di we aw dɛn kin trit am kin dipen pan bɔku tin dɛn, fɔ ɛgzampul:

• Tayp fɔ rijek.
• Di kayn we aw pɔsin nɔ gri fɔ tek am.
• Yu simptom dɛm.
• Ɔda wɛlbɔdi prɔblɛm dɛn we yu gɛt.
• Us mɛrɛsin yu de tek naw?

If yu gɛt at rijɛkt, dɔktɔ dɛn kin du tin lɛk:

• Fɔ chenj di kayn mɛrɛsin dɛn we yu de tek naw, ad nyu wan dɛn, ɔ fɔ mek di mɛrɛsin bɔku.
• Wan tritmɛnt we dɛn kɔl plasmapheresis ɔ photopheresis, we na wan we fɔ klin yu blɔd.
• Ɔpreshɔn ɔ ɔda tin dɛn fɔ mek blɔd flɔ fayn, lɛk fɔ du angioplasty ɔ ɔpreshɔn we pɔsin kin opin in at.
• Fɔ gi mɛrɛsin frɔm di kɔtikosterɔyd grup, fɔ ɛgzampul , Prednisone .
• Fɔ tek at frɔm nyu pɔsin we gi am ɛn du ritransplant (dis nɔ kin apin so ɔltɛm).
• Yuz mashin fɔ sɔpɔt yu at. Fɔ ɛgzampul:Ekstrakɔpɔrial Mɛmbran Ɔksijɛnɛt (ECMO) ɔ Vɛntrikular Ɛsist Divays (VAD) .

Wetin a go du fɔ mek mi at nɔ rijɛkt?

Sɔm tin dɛn de we yu kin du fɔ ɛp fɔ ridyus di risk fɔ lɛ dɛn nɔ gri wit yu:

• Mek shɔ se yu go na ɔl yu dɔktɔ apɔntinmɛnt dɛn. Dɛn tin ya rili impɔtant.
• Chek yu wet, blɔd prɛshɔn, ɛn bɔdi tɛmpracha ɔltɛm. Tɛl yu dɔktɔ if yu notis ɛni chenj.
• Fɔ fala di we aw yu de liv fayn layf. Dat min se yu fɔ it tin dɛn we gɛt fayn fayn tin dɛn, yu fɔ du ɛksɛsayz ɔltɛm, ɛn lɛf fɔ smok if yu de smok.
• If yu gɛt ɛni ɔda sayn we nɔ kɔmɔn, tɛl yu dɔktɔ wantɛm wantɛm, ɛn nɔ wet fɔ yu nɛks apɔntinmɛnt.
• Tek ɔl di mɛrɛsin dɛn we yu dɔktɔ tɛl yu fɔ tek jɔs lɛk aw dɛn tɛl yu fɔ tek am, di rayt tɛm, ɛn di rayt we. Nɔ mis wan doz.
• Bifo yu tek ɛni nyu mɛrɛsin (ivin vaytamɛn), aks yu dɔktɔ ɔ fama if i go mek yu gɛt prɔblɛm wit yu anti-rijekshɔn mɛrɛsin.

Wetin a fɔ ɛkspɛkt if dɛn nɔ gri fɔ tek mi?

Di risk fɔ mek yu at nɔ gri wit am kin go dɔŋ as tɛm de go. Bɔt i impɔtant fɔ mɛmba se dis kin stil apin sɔm ia afta dɛn dɔn du di ɔpreshɔn.

If yu gɛt rijekshɔn, yu dɔktɔ go tɔk to yu bɔt di tin dɛn we yu go ebul fɔ du. Bɔrku pipul kin mεnεj dis kכndyushכn wit inkrεsiv dכz כ f immunosuppressant εn כda tritmεnt dεm. Na 2% to 4% nɔmɔ pan pipul dɛm we gɛt at transplant go nid fɔ transplant bak.

Us kwɛstyɔn dɛn a fɔ aks mi dɔktɔ bɔt aw at nɔ de gri fɔ tek am?

Yu kin aks yu dɔktɔ kwɛstyɔn dɛn lɛk dɛn wan ya:

Bifo dɛn du di ɔpreshɔn:

• Dis donor in hat na gud match fo mi?
• Wetin a fɔ du fɔ mek a nɔ gɛt bɔku prɔblɛm wit mi at?
• Us antirejection mɛrɛsin dɛn a fɔ tek?
• Wetin na di bad tin dɛn we dɛn mɛrɛsin dɛn de kin du?
• Aw ɔltɛm a fɔ chɛk mi wet, mi blɔd prɛshɔn, ɛn di tɛmpracha na mi bɔdi? Us chenj dɛn a fɔ ripɔt to yu?

If pɔsin de we nɔ gri fɔ tek am:

• Us kayn rijekshɔn a gɛt?
• Us kayn tritmɛnt dɛn go ɛp mi?
• A fit fɔ gɛt ɔda at transplant?

Fɔ dɔn, mɛmba dis.

Rijekshɔn na tin we kin apin afta dɛn dɔn transplant yu at. I kin apin ɛnisay frɔm sɔm dez to ia afta dɛn dɔn du di ɔpreshɔn. So, i impɔtant fɔ de nia yu mɛdikal tim ɛn fala dɛn instrɔkshɔn dɛn gud gud wan.Tɔk wit yu dɔktɔ opin wan bɔt aw fɔ ridyus di risk fɔ lɛ dɛn nɔ gri fɔ tek yu ɛn di tritmɛnt dɛn we yu go gɛt. Nɔr wɔri, bɔrku advans we de naw fɔ mɛn dɛn kayn tin ya. Mɛmba se nɔto yu wangren de.

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