Dis fכns kin afekt yu lכng dεm tu? Lɛ wi lan bɔt Histoplasmosis!

Yu dɔn ɛva yɛri bɔt wan sik we dɛn kɔl ``Histoplasmosis''? Di nem kin tan lɛk se i strenj smɔl. Bɔt na fɛns infɛkshɔn we kin afɛkt wi lɔng ɛn na sɔntin we wi fɔ tek tɛm wit. Dis fungus de liv na di grɔn, mɔ na grɔn we gɛt bɔd ɔ bat dɔti. Wi kin gɛt dis sik if wi blo na dɔst we gɛt dis fɔŋ.

Wetin rili na Histoplasmosis?

fכ simpul wan, histoplasmosis na infεkshכn na wi lכng dεm we wan kayn fכns we dεn kכl ``Histoplasma capsulatum`` (``Histoplasma capsulatum`` כ ``H. capsulatum``) de kכz. Dis fεns de na di grכn na bכku pat dεm na di wכl, εn i kin kכmכn na kכntri dεm lεk Amerika. Yu kin si dis fɛns bak na wi Sri Lanka, mɔ na di grɔn we de rawnd bat kev dɛn, ol bildin dɛn, ɛn bɔd fam dɛn. i de go insay wi bכdi we wi de blo dכst we gεt dεn fכn spכr dεm ya.

Yu tink se difrɛn kayn dis sik de?

Yes, sɔm men kayn histoplasmosis de. Dɔktɔ dɛn kin no dɛn kayn tin ya bay aw lɔng yu dɔn gɛt di sik ɛn if i dɔn pas to ɔda pat dɛn na yu bɔdi.

1. Akyu pulmonari histoplasmosis

Dis na di kayn infεkshכn we kin kכmכn pas כl. Na lɛk 10% pan di pipul dɛm wae gɛt di fungus kin gɛt sɔm kayn sik dɛm wae tan lɛk nyumonia. Dɛn tin ya na fiva, kɔf, ɛn i nɔ kin izi fɔ blo. Bɔt if yu gɛt infekshɔn we nɔ gɛt bɛtɛ grɛt, di sayn dɛn kin bi smɔl ɛn i kin las fɔ sɔm mɔnt. Dɛn kɔl dis sɔbakut stej.

2. Krכnik kavita pulmonari histoplasmosis

Dis na sik we kin de fɔ lɔng tɛm. I kin mɔs pan pipul dɛm wae gɛt lכng sik lεk εmfysema ɔr COPD (Chronic Obstructive Pulmonary Disease). Di sayn dɛm kin smɔl pas di akyu fɔm, bɔt yu kin swet na nɛt ɛn yu kin lɔs yu wet. Di sayn dɛm kin te fɔ sɔm mɔnt, ivin fɔ lɔng tɛm. I kin tan lɛk TB smɔl. If dɛn nɔ trit am, di damej we de na di lɔng dɛn go bɔku smɔl smɔl.

3. Progresiv disiminet histoplasmosis

dis na we di H. capsulatum fכns de spre frכm di lכng dεm to כda pat dεm na di bכdi. Dis kin apin to pipul dɛm wae gɛt bɔrku wik imyun sistɛm, lɛk di wan dɛm wae gɛt advans HIV infɛkshɔn. Dis kin mek yu gɛt sɔm kayn sik lɛk wae yu nɔr de blo fayn, yu taya, yu de lɔs yu wet, ɛn yu gɛt ɔlsa na yu skin.

pan tap dat, di kayn histoplasmosis de we de afekt di bren (sεntri nεv sεstem histoplasmosis) εn di wan dεm we de afekt di yay dεm (ocular histoplasmosis).

Aw kɔmɔn tin na di histoplasmosis?

infakt, dεn εstimat se lεk 75% pan di big pipul dεm we de liv na say dεm we di fכns `H. capsulatum` na kכmכn dεn bin infεkt wit dis fכns na sכm tεm. Bɔt bɔku pipul dɛn nɔ kin gɛt ɛni sayn fɔ sho se dɛn gɛt dis sik.

Wetin dis fכs de du to wi bכdi?

Imajin, yu inhal dis `H. capsulatum` fungus wit dɔst. Dɔn i kin go stret na yu lɔng dɛn. na de, dis fכns de go insay wi wayt bכdi sεl dεm εn i de chenj frכm `mכld` fכm to `yist` fכm we kin infεkt.

pan bכku pipul dεm, di imyun sεl dεm na di bכdi de pwεl di fכn כ fכ mek spεshal kכva dεm we dεn kכl ``granulomas`` we de rawnd di fכn εn mek i nכ du di bכdi. Dis kin mek wi nɔr kin gɛt ɛni sayn fɔ si dis sik.

Bɔt sɔmtɛm dis kin bi sik:

• If yu inhal bɔku bɔku fɛns wan tɛm, yu imyun sistɛm kin ful-ɔp, ɛn dis kin mek yu gɛt sayn dɛn we tan lɛk flu ɛn i kin at fɔ blo.
• If yu gɛt sik dɛn na yu lɔng lɛk COPD, dis fɛns kin kɔntinyu fɔ pwɛl yu lɔng.
• If yu imyun sistεm wik (e.g., dεn wan dεm we gεt HIV כ dεn wan dεm we de tek imyun supεshכn dεm), dis fכns kin yuz yu imyun sεl dεm fכ spre to כda pat dεm na yu bכdi. Dis kin mek prɔblɛm dɛn we kin mek pɔsin in layf de pan denja.

Wetin na di sayn dɛm fɔ histoplasmosis?

Di sayn dɛm fɔ histoplasmosis kin bi:

• Fiva
• Kɔf
• We pɔsin de swet
• I nɔ izi fɔ blo (dyspnea) .
• Chɛst de pen
• Ɛd we de at (ed we de at) .
• Mɔsul dɛn kin pen
• Rɛd, lumpy rash na di ɔda leg dɛn (erithema nodosum) .

Pipul wae gɛt krɛse hade pulmonary histoplasmosis kin gɛt swet bak na nɛt ɛn dɛn kin lɔs dɛn wet. Impɔtant tin na dat, lɛk 90% pan di pipul dɛn we de inhal di fεns H. capsulatum nɔ kin gɛt ɛni simptom, ɔ di simptom dɛn kin sɔlv fɔ dɛnsɛf.

Wetin kin mek pɔsin gɛt dis sik?

di kכz fכ dis na wan fכns we dεn kכl ``Histoplasma capsulatum``. As wi bin dɔn tɔk, i kin kam we yu inhal mold spɔr frɔm grɔn we gɛt dis fɛns. Dis fɛns de gro fayn fayn wan na grɔn we gɛt bat dɔti ɛn bɔd dɔti. I de na bɔku say dɛn na di wɔl:

• Insay di Oayo ɛn Misisipi Riva vali dɛn na Amɛrika.
• Na Sɛntral ɛn Sawt Amɛrika.
• Na Afrika.
• Na Eshia.
• Na Ɔstrelia.

Bɔrku pipul nɔr kin sik wae dɛn de blo dis fungus, bɔt sɔm pipul dɛm, mɔr di wan dɛm wae kin inhal bɔrku bɔrku pan di fungus wan tɛm ɔr wae gɛt sɔm kayn wɛl bɔdi prɔblɛm, kin gɛt sɔm kayn sik.

Udat de pan big risk fɔ dis?

Yu de pan big risk if yu wok ɔ di tin dɛn we yu lɛk fɔ du na fɔ stɔp dɔst na say dɛn we dis fɛns de bɔku. Ɛgzampul dɛn:

• Spelunking we yu de du.
• Fɔ du fam wok.
• Fɔ mɛn kɔk ɔ ɔda bɔd dɛn.
• Fɔ pwɛl ol bildin dɛn, kɔnstrɔkshɔn wok. Imajin, we yu de klin wan ol os we dɛn nɔ de yuz fɔ lɔng tɛm, if bat de na di ruf, ɛn da dɔti de miks wit di dɔst? Risk de if yu blo am insay.

Udat de pan ay risk fɔ gɛt histoplasmosis, ilɛksɛf na akyu ɔ krɛse?

• Fɔ di wan dɛn we gɛt wik imyun sistɛm. Di men rizin fɔ dis na HIV infɛkshɔn ɛn fɔ tek mɛrɛsin dɛn we de mek pɔsin nɔ ebul fɔ fɛt di sik.
• Fɔ di wan dɛn we gɛt COPD ɔ ɛmfisɛma.
• Fɔ pipul dɛn we dɔn pas 55 ia ɛn pikin dɛn we nɔ rich 1 ia yet.

Wetin na di prɔblɛm dɛn we kin apin we pɔsin gɛt histoplasmosis?

Bɔku siriɔs prɔblɛm dɛn de we kin apin bikɔs ɔf dis:

• Ska ɔ ɔda damej pan di lɔng dɛn.
• fibrosing mediastinitis - Dis na skata na di eria bitwin di lכng dεm.
• `Akyu Respiratory Distress Sindrom (ARDS)`.
• Sεntri nεv sεstem histoplasmosis - If di fכns spre to di bren, simptom dεm lεk di bren swel, ed we de at, kכnfyushכn, i at fכ tink, εn paralayz kin apin.
• Ocular histoplasmosis - if di fכns spre to di yay dεm, i kin mek yu si fayn כ i kin lכs.
• I kin spre to ɔda pat dɛn na di bɔdi lɛk di liva, di splin, di bon mɛro, ɛn di skin.

Aw yu kin no dis sik?

Dɔktɔ kin tɛst yu blɔd, urine, sputum frɔm yu lɔng, bon mɛro, ɔ wan sampul pan di tisu we afɛkt fɔ no if yu gɛt di sik. Dɛn kin yuz dɛn sampul ya fɔ:

• Wan kɔlchɔ fɔ di fungus `H. capsulatum` na di wan we dɛn de tray fɔ du. Dis na di bεst we fכ no di histoplasmosis. Bɔt dis kin tek lɔng tɛm, te to sɔm wiks. If tin tranga, yu dɔktɔ kin bigin fɔ trit yu ɛn nɔ wet fɔ di rizɔlt.
• Wi de luk fɔ di yist fɔm `H. kapsulatum`.
• Dɛn kin tɛst yu fɔ sayn dɛm (antijen ɔ antibodi dɛm) fɔ H. capsulatum na yu bɔdi.

pan tap dat, dεn kin du chεst εks-ray כ CT skan fכ luk fכ chenj כ damej we H. capsulatum kכz. De kayn tɛst wae yu dɔktɔ de yuse de dipen pan us kayn histoplasmosis yu gɛt ɛn aw yu sik dɛn kin tranga.

Wetin na di tɛst dɛn we dɛn kin du fɔ no if pɔsin gɛt sik?

Apat frɔm ɛkstrem rayt ɛn CT skan, dɔktɔ kin tek wata ɔ tisu sɛmpul fɔ luk fɔ sayn dɛn fɔ H. capsulatum ɔ fɔ kɔlchɔ am. Dɛn kin tek dɛn sampul ya di we dɛn we de dɔŋ ya:

• Yurin ɔ sputum tɛst : Yu de pis insay kɔp (yurin tɛst) ɔ sputum insay tiub (sputum tɛst).
• Blɔd tɛst dɛn: Dɔktɔ go tek sɔm blɔd na yu an wit nidul.
• Bayopsi : Dɛn kin tek wan sampul pan di tisu tru smɔl say we dɛn kɔt ɔ wit nidul. insay bon mכro bayopsi, dεn kin tek sεmpl frכm insay di hip bon.
• Bronchoscopy : Dɔktɔ go luk insay yu lɔng dɛn yuz wan tin we gɛt layt (bronchoscope). dis tεm, dεn kin du wan prכsidכm we dεn kכl bכnkoalvεolar lavage (BAL). dis involv fכ "wash" sכm sכm pat dεm na yu lכng wit wata, kכlekt di likid, εn sεnd am to lab fכ tεst.

Aw dɛn kin trit histoplasmosis?

Dɛn kin trit histoplasmosis wit antifungal mɛrɛsin, if nid de. If yu gɛt sɔm kayn sik, dɛn nɔr dɔn de fɔ lɔng tɛm, ɛn yu nɔr de pan big risk fɔ gɛt siriɔs infekshɔn, yu dɔktɔ kin disayd fɔ wet fɔ sɔm tɛm bifo i gi yu mɛrɛsin wantɛm wantɛm.

Yu tink se kɔmplit mɛrɛsin de fɔ dis?

Yes, bɔku tɛm dɛn kin mɛn histoplasmosis wit antifungal mɛrɛsin pan pipul dɛn we gɛt wɛlbɔdi imyun sistɛm. Yu dɔktɔ kin gi yu mɛrɛsin dɛn lɛk:

• `Itrakonazɔl`
• Amfɔterisin B (AmB) .
• `Kɔtikosterɔyd` (Dɛn kin gi dɛn tin ya na sɔm spɛshal kes dɛm, lɛk fɔ ridyus di swɛlin)

Wetin kin apin if dɛn nɔ trit am?

If yu imyun sistɛm de wok fayn ɛn yu nɔ gɛt ɛni ɔda ɔndalayn kɔndishɔn, histoplasmosis kin ɔltɛm go fɔ insɛf. Bɔt if dɛn nɔ trit am, sɔntɛnde i kin go ɔda pat na di bɔdi, mɔ if yu imyun sistɛm nɔ de wok fayn. I kin mek bak di lכng damej pan pipul dεm we gεt כndalayn lכng kכndyushכn.

Yu tink se dɛn kin ebul fɔ mek dɛn nɔ gɛt histoplasmosis?

If yu de na say we dis fכn de kכmכn, i kin rili at fכ avכyd fכ brith di fכn `H. kapsulatum`. Pan ɔl we i nɔ pɔsibul fɔ mek yu nɔ gɛt am kpatakpata, sɔm tin dɛn de we yu kin du fɔ ridyus yu risk:

• Nɔ go na say dɛn we gɛt dɔti dɔti ɔ usay bɔd ɔ bat dɛn de.
• If yu wok ɔ yu ɔbi nid fɔ de in kɔntakt wit grɔn we kin gɛt H. capsulatum, wɛr N95 mask. I go filta di briz we yu de blo te to sɔm mak.

Wetin a kin ɛkspɛkt if a gɛt histoplasmosis?

Wetin kin apin we yu gɛt histoplasmosis de dipen pan aw i tranga ɛn if yu gɛt ɔda ɔndalayn kɔndishɔn. Fɔ pipul dɛm wae gɛt wɛl bɔdi imyun sistɛm ɛn wae gɛt smɔl smɔl sik dɛm, yu dɔktɔ kin disayd fɔ "watch ɛn wet" wae yu nɔr gɛt mɛrɛsin. If yu imyun sistɛm wik ɔ yu sik bad bad wan, yu kin nid fɔ tek antifungal mɛrɛsin fɔ at le wan ia.

di tritmεnt kin te 6-12 wik כ pas dat fכ akyu pulmonary histoplasmosis. If di sik dɛn we nɔ de mɛn ɔ we kin rili bad, dɛn kin nid fɔ tek mɛrɛsin fɔ mɛn di fɛns fɔ at le wan ia.

Wetin na de chans fɔ mek yu nɔr gɛt dis sik?

Bɔrku pipul dɛm wae gɛt wɛl bɔdi imyun sistɛm (lɛk 96%) kin wɛl frɔm histoplasmosis wit tritmɛnt. Bɔt sɔm stɔdi dɛn sho se di rit we pipul dɛn we gɛt wik imyun sistɛm kin day kin bi bitwin 25% ɛn 37%. Na dat mek pipul dɛm wae gɛt wik imyun sistɛm nid fɔ tek tɛm mɔ.

Aw a kin kia fɔ misɛf?

If yu gɛt wik imyun sistɛm, ɔ if yu gɛt COPD ɔ ɛmfisema, yu fɔ tek ɛkstra step fɔ ridyus yu risk fɔ gɛt histoplasmosis. If yu de na say usay H. capsulatum kin bɔku, aks yu dɔktɔ if ɛni spɛshal tin de we yu kin tek fɔ protɛkt yusɛf.

Ustɛm a fɔ go to dɔktɔ?

If yu sik, lɛk fiva, kɔf, ɛn shɔt briz nɔr bɛtɛ insay wan wik, ɔr if dɛn de wɔs as tɛm de go, go to dɔktɔ. Tɛl yu dɔktɔ if yu dɔn gɛt dis fɛns tru yu wok ɔ tin dɛn we yu lɛk fɔ du, ɔ if yu dɔn travul go na say usay dis fɛns de.

Ustɛm a fɔ go na Imejɛnsi Tritmɛnt Yunit (ETU) ?

If yu imyun sistɛm wik ɛn yu gɛt sayn dɛn fɔ se yu gɛt infekshɔn, yu fɔ tɔk to dɔktɔ ɔ go na di imejensi rum wantɛm wantɛm. If yu gɛt siriɔs sik, go na di imejensi rum we de nia yu. Dɛn kayn sayn ya na:

• Ay fiva (we pas 103 Fahrenheit/40 Celsius).
• I nɔ kin izi fɔ yu fɔ blo bad bad wan ɔ wantɛm wantɛm.
• Chɛst de pen.
• If yu kɔf blɔd.
• Disorientation ɔ ɔda chenj dɛn na yu maynd.
• Di sik dɛn we kin mek pɔsin sik.
• blu kכla fכ di skin, lip, כ finga nεl (`cyanosis` - dis na sayn fכ lכw כksijεn na di bכdi).

Us kwɛstyɔn dɛn a fɔ aks di dɔktɔ?

I go fayn fɔ aks dɔktɔ kwɛstyɔn dɛn lɛk dɛn wan ya:

• A de pan risk fɔ gɛt siriɔs histoplasmosis?
• Us spɛshal step dɛn a fɔ tek fɔ ridyus di risk fɔ gɛt histoplasmosis?
• Us sayn dɛn a fɔ luk fɔ?
• Ustɛm a fɔ go na di imejensi rum?

Fɔ dɔn, tin dɛn fɔ mɛmba (Take-Home Message) .

Histoplasmosis na wan fεn infεkshכn we de afekt yu lכng. I kin tranga fɔ avɔyd if yu de na say usay dis fɛns de gro fayn fayn wan. Bɔt bɔku pan di kes dɛn nɔ kin siriɔs ɛn dɛn kin sɔlv fɔ dɛnsɛf.

Bɔt if yu gɛt lɔng prɔblɛm ɔ yu imyun sistɛm wik, yu kin gɛt siriɔs prɔblɛm dɛn frɔm histoplasmosis. So, i impɔtant fɔ mek yu ɛn yu dɔktɔ wok togɛda fɔ mek wan plan fɔ protɛkt yu wɛlbɔdi ɛn fɔ de wach fɔ ɛni sik. Nɔ panik, awareness na di bɛst difens!

` Histoplasmosis, fכn infεkshכn, lכng sik, Histoplasma capsulatum, bכd dכp, bat dכp, difεlεns fכ brith