Lɛ wi lan bɔt di Human Growth Hormone (HGH) insay simpul wɔd dɛn.

Yu fil se yu pikin nɔ de gro lɛk aw dɛn fɔ gro? Ɔ yu kin fil taya ɛn taya ɔltɛm? Sɔntɛm di rizin fɔ dis na wan smɔl kemikal mɛsenja na yu bɔdi. Wan pan dɛn kayn ɔmon dɛn de we impɔtant fɔ mek wi bɔdi gro ɛn bɔku ɔda tin dɛn, dɛn kɔl am human growth hormone . Wi kin kɔl am HGH (Human Growth Hormone) fɔ shɔt tɛm. Sɔm pipul dɛn kin kɔl am bak somatotropin . So tide, lɛ wi tɔk bɔt dis HGH ditayli, rili simpul.

Wetin na HGH? Aw i de mek na wi bɔdi?

Fɔ tɔk am simpul wan, HGH na natura l ɔmon we wi bɔdi de mek. Na wan smɔl gland we de jɔs dɔŋ wi bren, we di sayz lɛk smɔl bon, de mek am. Wi kin kɔl am di pituitary gland . Dis HGH ɔmon de afɛkt bɔku pat dɛn na wi bɔdi. I rili impɔtant fɔ mek pikin dɛn gro . HGH de ɛp bɔku pan tin dɛn lɛk fɔ mek yu pikin lɔng ɛn fɔ mek dɛn bon dɛn strɔng.

כltu, wans wi gro, dat na afta di growth plet dεm na wi bon dεm (epiphyses) dכn klos, HGH nכ de mek wi tכl igen. Bɔt nɔto dat nɔmɔ HGH de du. ivin afta wi gro, HGH de εp fכ mεnten di nכmal strכ kchכ na wi bכdi εn kip wi mεtabolism de rכn fayn fayn wan. dis mεtabolism na in de tכn di it we wi de it to enεji. HGH de ɛp bak fɔ kip wi blɔd shuga (glukɔs) lɛvɛl na wan patikyula lɛvɛl.

Ɔmon na kemikal dɛn we de na wi bɔdi. Dɛn de du tin lɛk mɛsenja. Dɛn kin travul tru di blɔd ɛn tɛl wi ɔgan dɛn, mɔsul dɛn, ɛn ɔda tisu dɛn wetin fɔ du ɛn ustɛm fɔ du am. I pas 50 pan dɛn ɔmon dɛn ya na wi bɔdi!

Di pituitary gland we a bin dɔn tɔk bɔt de na di bren, dɔŋ di haypothalamus . Dis haypothalamus de kɔntrol bɔku tin dɛn lɛk wi blɔd prɛshɔn, at rit, bɔdi tɛmpracha, ɛn di we aw wi de digest. so, dis haypothalamus na in de tεl di pituitary gland fכ rilis HGH. Wan ɔmon we de ɛp wit dat na in dɛn kɔl GHRH (grɔwth ɔmon-rilis ɔmon) . כlso, כda כmon (somatostatin) de kכmכt frכm di haypothalamus fכ stכp di rilis fכ HGH. Dis na aw dɛn kin kɔntrol HGH.

Sɔntɛnde, dɔktɔ dɛn kin yuz sintetik HGH fɔ trit sɔm sik dɛn. Bɔt mɛmba se, nɔ ɛva yuz sintetik HGH we yu nɔ gɛt dɔktɔ in prɛskrishɔn.

Us tin dɛn kin afɛkt di we aw HGH de kɔmɔt?

wi pituitary gland nכmal fכ rilis HGH sכm sכm כl di de, we dεn kכ l puls . dis na tu כmon dεm we de kכmכt na di haypothalamus we dεn kכl GHRH εn somatostatin de kכntro am.

Nɔto dat nɔmɔ, ɔda ɔmon dɛn de insay. Fɔ ɛgzampul,insulin-layk growth factor 1 (IGF-1) de dכn HGH prodakshכn, we כmon dεm lεk thyroxine , glucocorticoids , εn ghrelin de inkrεs HGH rilis.

IGF-1 we wi liva de kכmכt na di mεjכr bayprodukt fכ HGH aktiviti. dis IGF-1 na in de kכntro di כvaprodakshכn fכ HGH. dat min se, HGH de mek IGF-1 prodyuz, εn di IGF-1 we dεn prodyuz de ridyus di prodakshכn fכ HGH bak. I tan lɛk saykl.

pan hεlty pכsin, di HGH rilis de inhibit bay di hכy bכdi shuga lεvεl (hyperglycemia) . pan tap dat, tin dεm lεk slip, strεs, εksεsayz, lכw bכdi shuga lεvεl (hypoglycemia) , εn amino asid dεm de mek di HGH kכmכt .

Wetin na di men wok we di HGH ɔmon de du?

HGH gɛt tu men wok dɛn:

1. Fɔ mek pikin dɛn gro (espɛshali pan pikin dɛn) .

2. Afekt di mεtabolism (di we aw wi de kכnvכlt di it we wi de it to enεji) .

HGH ɛn growth

HGH de ɛp ɛvri tisu ɛn ɔgan na wi bɔdi fɔ gro. Bɔt i gɛt nem pas ɔl fɔ ɛp di katilej ɛn bon fɔ gro. Dis impɔtant mɔ we pɔsin de yɔŋ. di sεl dεm we dεn k כl kכndrכsayt dεm na di kכtilaj εn di כstioblast dεm na di bon dεm de gεt signal frכm HGH fכ divayd εn gro big.

כltu, lεk aw a bin se, HGH nכ de inkrεs di ayt afta di growth plet dεm (epiphyses) na pikin in bon dεm dכn klos. bifo dat, HGH de εp fכ mεnten nכmal bכdi strכkchכ tru כl di layf.

HGH ɛn mɛtabolism

mεtabolism na di kεmikכl prכsεs we de tכn di it we wi de it to εnεji. Ɛvri sɛl na wi bɔdi nid ɛnaji fɔ mek i ebul fɔ wok fayn fayn wan.

HGH de afekt mεtabolism fכs bay we i de inkrεs di prodakshכn fכ IGF-1, we de chenj di we aw i de afekt wi bכdi in sεl dεm. IGF-1 na ɔmon we gɛt di sem we lɛk insulin . Insulin na impɔtant ɔmon we wi pankrias de mek we de mek di shuga (glukɔs) we de na di blɔd go dɔŋ. IGF-1 gɛt di pawa bak fɔ mek di blɔd shuga go dɔŋ.

Nɔmal wan, wi bɔdi kin tek tɛm kɔntrol di lɛvɛl we di glukɔs de na wi blɔd. Blɔd glukɔs ɔ shuga na di men kayn shuga we de na wi blɔd. Wi kin gɛt am frɔm di it dɛn we gɛt kabɔhaydrɛt we wi kin it. Dis shuga na in de gi ɛnaji to wi ɔgan dɛn, mɔsul dɛn, ɛn nervɔs sistɛm.

Insulin na di men ɔmon we de mek di blɔd shuga go dɔŋ we i bɔku. Ɛn di ɔmon we dɛn kɔl glukagon kin mek di blɔd shuga bɔku we i nɔ bɔku. Bɔt HGH kin mek di blɔd shuga go ɔp we i smɔl. Bɔt,If di amount of HGH na yu bɔdi go ɔp tumɔs, i kin ambɔg di akshɔn we insulin de du ɛn mek di blɔd shuga lɛvɛl go ɔp.

Yu tink se HGH rili mek yu lɔng?

Yes, HGH kin mek pikin dɛn ayt mɔ ɛn mɔ. Bɔt dat na bifo di plet dɛn we de gro na dɛn bon dɛn dɔn jɔyn. HGH nɔ kin mek yu lɔng afta di growth plet dɛn dɔn jɔyn. Bifo dat, afta yu dɔn rich yu maksimal ayt, HGH de ɛp fɔ mek yu bɔdi in strɔkchɔ ɛn mɛtabolism kɔntinyu fɔ de.

Wetin na di nɔmal lɛvɛl dɛn fɔ HGH?

As a bin se, di pituitary gland de rilis HGH in burst tru di de. Dɛn lɛvɛl ya kin difrɛn difrɛn wan bay di tɛm na di de, di ej, ɛn di man ɔ uman. So, wan blɔd tɛst fɔ no HGH nɔ kin rili yusful fɔ no wan kɔndishɔn. Bifo dat, di dכkta dεm de luk pan di HGH lεvεl dεm tru spεshal tεst dεm (stimulashכn כ suprεshכn tεst dεm).

di nכmal HGH lεvεl dεm na dεn wan ya:

• big man dεm: 0.4 to 10 nanogram pan wan mililita (ng/mL) .
• Adult uman: 1 to 14 nanogram pan wan mililita (ng/mL) .
• Pikin dεm: 10 to 50 nanogram pan wan mililita (ng/mL) .

Bɔt mɛmba se dɛn valyu ya kin difrɛn smɔl frɔm wan lab to ɔda lab. So kɔmpia dɛn to di nɔmal rɛnj na yu lab ripɔt. If yu gɛt ɛnitin we de mɔna yu, mek shɔ se yu tɔk to yu dɔktɔ.

Wetin kin apin if di HGH lɛvɛl dɛn go dɔŋ? (Grɔw ɔmon Dɛfisiɛns) .

we di HGH lεvεl dεm dכn lכs pas nכmal, wi kin kכl am Growth Hormone Deficiency . Dis kin bi bikɔs ɔf sɔm prɔblɛm ɔ damej pan di pituitary gland. Dis kin mek yu gɛt wan sik we dɛn kɔl hypopituitarism . Dis min se wan ɔ mɔ ɔmon dɛn we di pituitary gland de mek kin ridyus. HGH na ɔmon bak we kin afɛkt dis we.

Dis HGH dɛfisiɛns kin afɛkt big pipul ɛn pikin dɛn difrɛn we dɛn.

If di HGH lεvεl dεn dכn pan big pipul dεm:

If big pɔsin in HGH lɛvɛl go dɔŋ, dɛn prɔblɛm ya kin apin:

• Di gladi at ɛn satisfay wit layf nɔ de igen.
• Di fat we de na di bɔdi we de bɔku.
• Di risk fɔ gɛt at sik kin bɔku.
• di at, di mכsul dεm εn di bon dεm we de wik.

pan big pipul dεm, dis kכndyushכn kin kכz bay wan pituitary adenoma (dis nכto kεnsar, bכt na tכmכro) כ di damej pan di pituitary gland/hypothalamus.

If pikin dɛn gɛt smɔl HGH:

if di pikin in HGH lεvεl dεn dכn, i go stכnt fכ gro. Di men sayn na we di pikin de go ɔp sloslo afta di pikin in tɔd batde. Dat min se, i nɔ rich 1.4 inch insay wan ia. Fɔ ɛgzampul, if i tan lɛk se yu pikin shɔt pas di ɔda pikin dɛn na di klas, yu fɔ wɔri.

Apat frɔm dat, pikin we nɔ gɛt HGH kin gɛt sɔm sayn dɛn bak lɛk:

• Fes we luk yɔŋ pas in ej fa fawe.
• Di ia we nɔ de gro fayn.
• Dilay we pɔsin kin rich fɔ bɔn pikin.

Dɛn kin bɔn pikin dɛn wit dis sik. sכmtεm dεn nכ no di kכz (idiopathic), i kin bi jεnεtik, כ i kin kכz fכ di damej pan di pituitary gland we uman bεlε כ we i bכn. Sɔntɛnde i kin kam bak we di pituitary gland ɔ di haypothalamus kin pwɛl leta we i dɔn day.

Wetin kin apin if di HGH lɛvɛl go ɔp?

di men kכndishכn we de asai wit hכy pas nכmal lεvεl dεm fכ HGH na akromegali . Dis kin afɛkt big pipul ɛn pikin dɛn bak difrɛn we. Na wan sik we nɔ kin apin so ɔltɛm.

Akromegali na big pipul dɛn

Di big pipul dɛm we gɛt akromegali kin gɛt big ɔ swɛlin an ɛn fut ɛn chenj na dɛn fes .

Dɛn kin gɛt tik bon dɛn bak ɛn dɛn kin gɛt big pat pan dɛn insay. Dɛn kin gɛt sik lɛk aypatɛnshɔn , tayp 2 dayabitis, ɛn at sik. mכr dan 99% pan di akromegali kes dεm na di tכmכro dεm we nכ de kεnsar na di pituitary gland we dεn kכl pituitary adenomas . dis tכmכro dεm kin mek tu mכch HGH. Akromegali kin kכmכn mכst afta midul ej, afta di growth dכn kכmplit. So, big pipul dɛm we gɛt akromegali nɔ kin gro lɔng. Bifo dat, dɛn bon dɛn kin tik.

Akromegali (Gigantism) na pikin dɛn

Na smɔl tɛm nɔmɔ, pikin dɛn kin gɛt ay HGH lɛvɛl bifo dɛn rich dɛn ful ayt. Dis kin mek di lɔng bon dɛn gro pasmak, ɛn dis kin mek pikin dɛn lɔng pasmak. Dɛn kɔl dis sik juvenile acromegaly . Sɔntɛnde dɛn kin kɔl am gigantism . If dɛn nɔ trit dɛn pikin ya, dɛn kin lɔng fɔ sɛvin fit ɔ lɔng pas dat. Dɛn kin gɛt sɔm sayn dɛm bak lɛk wae dɛn kin taya, dɛn kin delay fɔ bɔn pikin, ɛn ed kin at.

Dis kin bi bak bikɔs ɔf di pituitary adenoma.

Aw dɛn kin mɛzhɔ di HGH lɛvɛl dɛn?

If yu ɔ yu pikin gɛt sɔm sayn dɛn we de sho se dɛn gɛt prɔblɛm dɛn we gɛt fɔ du wit HGH, yu dɔktɔ kin ɔda fɔ mek dɛn du bɔku blɔd tɛst fɔ chɛk yu HGH lɛvɛl.

As a bin se, di pituitary gland de rilis HGH insay di blɔd ɔl di de ɛn wan wan tɛm na nɛt. So, i nɔ kin izi fɔ ɔndastand di tin kɔrɛkt wan bay we yu tek blɔd ɛn chɛk HGH wan tɛm nɔmɔ.

So, bɔku tɛm, dɔktɔ dɛn kin yuz we dɛn we dɛn kɔl growth hormone stimulation ɛn suppression test fɔ no di kɔndishɔn dɛn we HGH nɔ de ɔ we i pasmak.

Apat frɔm dat, dɛn kin du blɔd tɛst fɔ chɛk di IGF-1 (insulin-like growth factor 1) lɛvɛl.

Aw dɛn kin yuz HGH as mɛrɛsin?

Di United States Food and Drug Administration (FDA) dɔn gri fɔ mek dɛn yuz sintetik HGH fɔ trit sɔm sik dɛn. Dis sintetik HGH kin ɔlrɛdi gɛt wit dɔktɔ in prɛskrishɔn, ɛn dɛn kin gi am as injɛkshɔn.

Dɛn kin gi pikin dɛn HGH fɔ dɛn kɔndishɔn ya:

• Di ɔmon we de mek pɔsin gro.
• Kɔndishɔn dɛm wae kin mek pɔrsin gɛt shɔt ayt, lɛk krεse sik na in kidni , Turner syndrome , ɛn Prader-Willi syndrome .

Dɛn kin gi HGH fɔ big pipul dɛn fɔ dɛn kɔndishɔn ya:

• Di ɔmon we de mek pɔsin gro.
• Lɔs pan mɔsul mas bikɔs ɔf HIV .
• Short bowel syndrome we gɛt di sik .

I rili impɔtant: Nɔ ɛva yuz sintetik HGH pas yu dɔktɔ tɛl yu fɔ du am.

Wetin na di sayd ɛfɛkt dɛm fɔ sintetik HGH?

Sɔm sayd ɛfɛkt kin apin we yu de yuz sɛntetik HGH as mɛrɛsin. Dɛn tin ya na:

• Carpal tunnel syndrome (wan pinch nerve na di wrist).
• Inkris rɛsistɛns ɛn/ɔ tayp 2 dayabitis.
• Di an ɛn fut dɛn kin swel (ɛdima) .
• Pen na di jɔyn ɛn mɔsul dɛn.
• di brεst tisu we de big pan man dεm (gynecomastia) .
• Di risk fɔ gɛt sɔm kayn kansa kin bɔku.

Risach pipul dɛm stil nɔ gɛt inof infɔmeshɔn bɔt di lɔng tɛm ifɛkt dɛm we sɛntetik HGH tritmɛnt kin gɛt.

Ustɛm a fɔ si dɔktɔ bɔt HGH lɛvɛl?

If yu ɔ yu pikin gɛt sɔm sayn dɛn we gɛt fɔ du wit HGH we nɔ gɛt bɛtɛ tin ɔ we i pasmak (e.g., we yu de gro sloslo, yu an ɛn fut dɛn dɔn big), mek shɔ se yu go to yu dɔktɔ.

If yu dɔn ɔlrɛdi gɛt tritmɛnt fɔ wan abnɔmal tin na di HGH lɛvɛl, i rili impɔtant fɔ go to yu dɔktɔ ɔltɛm fɔ mek shɔ se yu tritmɛnt de wok fayn fayn wan.

HGH na pawaful ɔmon we impɔtant fɔ bɔku impɔtant tin dɛn we de apin na wi bɔdi. Sɔntɛnde, wi pituitary gland kin mek tumɔs ɔ tu smɔl pan am. If yu ɔ yu pikin gɛt ɛni wan pan dɛn sik ya, i go fayn fɔ mek yu tɔk to dɔktɔ. Dɛn de de fɔ ɛp yu.

Faynal Mɛsej fɔ Tek-Hom

Okay, so wi tok plenti abaut HGH tide, no bi so? Lɛ wi tɔk smɔl bɔt:

• HGH na ɔmon we rili impɔtant fɔ wi gro, mɔ we wi smɔl, ɛn fɔ wi bɔdi in mɛtabolism.
• Dis na di pituitary gland we de na wi bren de mek am.
• If di HGH lɛvɛl go dɔŋ, pikin dɛn kin dɔn stɔp fɔ gro, ɛn big pipul dɛn kin gɛt difrɛn wɛlbɔdi prɔblɛm dɛn bak.
• if di HGH lεvεl dεm inkrεs, kכndishכn dεm lεk akromegali kin apin.pan pikin dεm, dis kin sho lεk gigantism, we min se dεn de gro כlsay we nכ sכmtεm.
• If yu sɔspɛkt se yu ɔ yu pikin kin gɛt prɔblɛm wit HGH, nɔ shek fɔ go to dɔktɔ.
• Nɔ ɛva yuz sintetik HGH we yu nɔ gɛt dɔktɔ in prɛskrishɔn.

Mɛmba se ɔl dis na fɔ tich yu. If yu gɛt ɛnitin fɔ wɔri bɔt yu wɛlbɔdi biznɛs, na yu dɔktɔ nɔmɔ go ebul fɔ gi yu di bɛst sɔlv. Stay wit wɛlbɔdi!

` Human Growth Homon, HGH, Pituitary Gland, Pikin Growth, Ayt Gεn, Mεtabolism, Hכmon Imbalans