Yu kin taya ɔltɛm? Dis kin bi prɔblɛm wit yu pituitary gland? (Hypopituitarism) .

Sɔntɛnde yu kin fil lɛk se yu bɔdi wik, lɛk se sɔntin nɔ de? Sɔntɛm di rizin fɔ dis na smɔl prɔblɛm na wan pan di smɔl smɔl, bɔt rili impɔtant gland dɛn na yu bɔdi. Tide wi go tɔk bɔt hypopituitarism , we na wan sik we nɔ kin apin so ɔltɛm we kin apin na di pituitary gland . Nɔ wɔri, wi go tɔk bɔt dis simpul wan, di we we yu go ɔndastand.

Wetin na haypopituitarism?

Fɔ tɔk am simpul wan, hypopituitarism na we yu pituitary gland nɔ de mek inof ɔmon. Naw yu go mɔs de wɔnda wetin na dɛn ɔmon dɛn ya. Ɔmon dɛn tan lɛk kemikal mɛsenja dɛn we kin kɛr mɛsej dɛn fɔ mek wi bɔdi wok fayn. Di ɔmon dɛn we de na di pituitary kin kɔntrol bɔku tin dɛn, lɛk aw wi kin du tin wit in bɔdi , aw wi bɔdi kin gro, aw wi kin du mami ɛn dadi biznɛs, ɛn aw wi kin bɔn pikin.

Tink bɔt am lɛk smɔl kɔmand sɛnta na wi bɔdi, we na di pituitary gland. Bɔt i nɔ de wok in wan. Wan ɔda impɔtant pat na di bren we dɛn kɔl di haypothalamus de ɛp am . di haypothalamus de tεl di pituitary gland se, "Okay, rilis di כmon naw." di haypothalamus de kכntro bak tin dεm lεk bכdi prεshכn, at rεt, bכdi tεmprachכ, εn digεst. So, if ɛni damej ɔ sik de na di pituitary gland ɔ di haypothalamus, yu kin gɛt hypopituitarism.

Dis sik kin apin wantɛm wantɛm, ivin afta aksidɛnt. Ɔ i kin bigin smɔl smɔl fɔ sɔm mɔnt ɔ sɔm ia. Bɔrku tɛm, dɛn pipul ya go nid fɔ tek mɛrɛsin fɔ di res ɔf dɛn layf fɔ kɔntrol dɛn sik ya. Bɔt nɔ wɔri, yu dɔktɔ go de wach yu gud gud wan ɛn gi yu di tritmɛnt we yu nid.

Difrɛn kayn hypopituitarism de?

Yɛs, dɛn kin sheb am to tu men kayn. Wan pan dɛn de bay aw bɔku ɔmon nɔ de .

• Isolated pituitary deficiency: Insay dis, na wan pituitary ɔmon nɔmɔ nɔ de.
• Bɔku bɔku ɔmon dɛn we de na di pituitary: Dis na we tu ɔ mɔ pituitary ɔmon dɛn nɔ de.
• Panhypopituitarism: Dis na wan sik we nɔ kin rili siriɔs we ɔl di ɔmon dɛn we di pituitary gland de mek kin ridyus.

nεks, dεn kin klas dεm akɔdin to di kכz εn aw di pituitary gland de afekt :

• Praymari haypopituitarism: Dis kin kam bikɔs ɔf di damej ɔ sik we de afɛkt di pituitary gland dairekt wan.
• Sεkɔndari haypopituitarism: Dis kin kam bikɔs ɔf di damej ɔ sik we de na di haypothalamus. Mɛmba se na di haypothalamus na in de gi instrɔkshɔn to di pituitary gland.
• Idiopathic hypopituitarism: Sɔntɛnde, dɛn nɔ kin ebul fɔ fɛn di tin we kin mek i gɛt dis sik.

Wetin na di sayn dɛm wae de sho se yu gɛt Hypopituitarism?

Di sayn dɛm kin difrɛn difrɛn wan bay di ɔmon we nɔ de . Dɛn tin ya bak kin ɛp:

• Yu jɛnɛral .
• Yu ej we dis kɔndishɔn bigin .
• Di tin we kin mek pɔsin gɛt hypopituitarism.
• Aw di ɔmon dɛn bin de go dɔŋ kwik kwik wan .

Naw lɛ wi si us sayn dɛn de sho we ɛni ɔmon nɔ bɔku.

Di simptom dɛm fɔ di Growth Hormone (GH) Deficiency

Fɔ pikin dɛn we dɛn jɔs bɔn:

• Di blɔd shuga lɛvɛl smɔl (Hypoglycemia) .
• Fɔ gɛt man in penis we nɔmal (Micropenis) .

Fɔ yɔŋ pikin dɛn:

• Di grow kin slo pasmak ɔ nɔ kin slo atɔl. Fɔ ɛgzampul, if i tan lɛk se yu pikin nɔ de gro lɔng pas ɔda pikin dɛn we dɛn ej, dis kin bi sayn fɔ dis.
• Short ayt .
• Dilay ɔ absent sεks divεl כpmεnt we i de bכn.

Fɔ big pipul dɛn:

• Fɔ taya pasmak ɔltɛm . Fɔ fil lɛk se di batri dɔn day.
• Fɔ fil lɛk se yu nɔ gladi ɛn satisfay wit layf.
• I nɔ de du mami ɛn dadi biznɛs ɛn di we aw i want fɔ du mami ɛn dadi biznɛs .
• di fεt we de kכmכt bכku bכku wan, εspεshali rawnd di wεst .
• Di we aw pɔsin kin bia wit kol ɛn ɔt we i nɔ kin gɛt bɛtɛ .
• Di mɔsul dɛn we dɔn go dɔŋ .
• I nɔ gɛt bɛtɛ trɛnk ɛn i nɔ de bia we i de du ɛksɛsayz.

Di sayn dɛm we de sho se yu nɔ gɛt Tayroyd-Stimulating Hormone (TSH).

Fɔ pikin dɛn we dɛn jɔs bɔn:

• di mכsul dεm we de dכn (di limb dεm de fil se dεn nכ gεt layf).
• Lɔw bɔdi tɛmpracha (Hypothermia) .
• Fɔ fil se yu dɔn blo .
• Kray wit vɔys we nɔ gɛt natin ɛn we nɔ gɛt natin .

Fɔ yɔŋ pikin dɛn ɛn big pipul dɛn:

di sayn dεm fכ dis na di sem lεk di wan dεm we de sho se i gεt haypotayroyd , biכs di TSH כmon de mek di tayroyd gland fכ mek in yon כmon dεm.

• Taya pasmak .
• Dray skin ɛn ia de thin/lɔs .
• Banbɛlɛ .
• We yu de gɛt mɔ wet .
• Di mɔsul dɛn we wik .
• Di ebul we i nɔ ebul fɔ bia wit kol .
• Tin dɛm wae de mɛk pɔrsin fil lɛk wae pɔrsin gɛt pwɛl hat .
• Uman dɛn kin gɛt mɔnt we dɛn nɔ kin gɛt ɔltɛm ɔ dɛn kin gɛt bɔku blɔd pas aw dɛn kin blɔd .

di simptom dεm fכ fכlikul-Stimulayt כmon (FSH) εn/כ Luteinizing Hכmכn (LH) dεfisiεns

FSH ɛn LH na ɔmon dɛn we dɛn kɔl gonadotropin . Dɛn tin ya kin afɛkt wi riprodaktiv sistɛm dairekt wan .

Fɔ pikin dɛn we dɛn jɔs bɔn:

• Fɔ gɛt man in penis we nɔmal (Micropenis) .
• Testikul dɛn we nɔ de kam dɔŋ .

Fɔ yɔŋ pikin dɛn:

• Lak fכ divεlכpmεnt fכ di bכdi na gyal pikin dεm.
• Bɔy pikin dɛn tɛstikul nɔ kin big .
• di bכdi nכ de εkspiriεns in ayt inkrεs wan wan (growth spurt) we i de bכn.

Fɔ man dɛn:

• Di want fɔ du mami ɛn dadi biznɛs we de go dɔŋ .
• Taya pasmak .
• We pɔsin nɔ ebul fɔ bɔn pikin .
• Di prɔblɛm we kin mek pɔsin gɛt raytin .
• Di ia we de na in fes ɔ bɔdi we de lɔs .

Fɔ uman dɛn:

• Low libido .
• Taya pasmak .
• We pɔsin nɔ ebul fɔ bɔn pikin .
• Hot flash - Na wan filin we de mek yu wam wantɛm wantɛm na yu bɔdi.
• Menstrueshɔn we nɔ de ɔltɛm ɔ we yu nɔ de gɛt mɔnt kpatakpata (Amenorrhea) .
• di ia we de lכs na di bכdi we de dכn .
• If yu nɔ ebul fɔ mek yu mama in milk afta yu bɔn pikin .

Di simptom dɛm fɔ Adrenocorticotropic Hormone (ACTH ɔ Corticotropin) we nɔ de

Fɔ pikin dɛn we dɛn jɔs bɔn:

• Di blɔd shuga lɛvɛl smɔl (Hypoglycemia) .
• We yu de gɛt bɔku bɔku wet sloslo (Failure to thrive) . I tan lek se di pikin no de latch pan ivin if i de drink inaf milk.
• Di sik dɛn we kin mek pɔsin sik .
• Di skin we de yɔlɔ (Jaundice) .

Fɔ yɔŋ pikin dɛn ɛn big pipul dɛn:

• Taya pasmak .
• We yu de lɔs yu wet we yu nɔ gɛt ɛni rizin .
• Lɔw blɔd prɛshɔn (Hypotension) .
• Nɔs ɛn vɔmit .
• Di blɔd shuga lɛvɛl smɔl (Hypoglycemia) .
• Kɔnfyushɔn, we pɔsin nɔ de no natin .

Di sayn dɛm we de sho se pɔsin nɔ gɛt Prolactin

di men tin we de sho dis na we di mama in milk nכ de prodyuz afta dεn bכn pikin .

Di sayn dɛn we de sho se pɔsin nɔ gɛt bɛtɛ ɔksijɛn

• Prɔblɛm fɔ gi pikin in mama in bɛlɛ afta dɛn bɔn di pikin.
• I nɔ kin izi fɔ mek yu gɛt tayt padi biznɛs wit di pikin afta dɛn bɔn am.
• Nɔ gɛt sɔri-at fɔ di sɔfa we ɔda pipul dɛn de sɔfa.
• I nɔ kin izi fɔ tɔk to ɔda pipul dɛn.

Di simptom dɛm fɔ di Antidiuretic Hormone (ADH ɔ Vasopressin ɔ Arginine Vasopressin) we nɔ de

Fɔ pikin dɛn we dɛn jɔs bɔn:

• Fɔ vɔmit .
• Fiva dɛn we wi nɔ no wetin mek i gɛt .
• Fɔ kray pasmak .
• We yu de lɔs yu wet .
• Banbɛlɛ .
• Fɔ wet di dayapɛt ɔltɛm (Daypa dɛn we rili wet) .

Fɔ yɔŋ pikin dɛn:

• I nɔ izi fɔ tren fɔ tɔylɛt .
• Fɔ wet wet na bed .
• Fɔ taya kwik kwik wan .

Fɔ big pipul dɛn:

• Fɔ pis bɔku tɛm .
• Fɔ tɔsti pasmak .
• Ilɛktrɔlayt imbalans .

Impɔtant: Nɔ wɔri if yu gɛt wan ɔ tu pan dɛn sayn ya, bɔt if dɛn nɔr de chenj, i go fayn fɔ mek yu go to dɔktɔ.

Wetin na di tin dɛm wae kin mek pɔrsin gɛt hypopituitarism?

Bɔrku rizin kin de fɔ dis sik. Sɔntɛnde, ivin dɔktɔ dɛn nɔ kin ebul fɔ no di rayt tin we mek i apin. Jɛnɛral wan, i kin bi bikɔs ɔf tri men tin dɛn:

1. fכ kכmprεs di pituitary gland כ di haypothalamus.

2. Damej pan di pituitary gland ɔ haypothalamus.

3. Fɔ gɛt wan sik we nɔ kin apin ɔltɛm ɔ ɔda sik we kin mek pɔsin gɛt hypopituitarism.

di kכndishכn dεm we de afekt di pituitary gland כ di haypothalamus

di kכndyushכn dεm wae kin put prεshכn pan dεn pat dεm ya na di bren εn mek yu gεt haypopituitarism na:

• di pituitary adenomas: dis na benign tכmכro dεm we de fכm na di pituitary gland. Dɛn kin chenj di we aw dɛn de mek ɔmon dɛn.
• di tכmכro dεm na di bren: di tכmכro dεm we de divεlכp nia di haypothalamus כ pituitary gland kin ambɔg di כmon dεm we de mek di כmon dεm.
• Limfosaytik haypophysitis (LH): Dis na wan sik we nɔ kin apin so ɔltɛm. na ya, sεl dεm we dεn kכl limfosayt dεm de invayd di pituitary gland. (Dis LH nɔ fɔ kɔnfyus wit di Luteinizing Hormone we wi bin dɔn tɔk bɔt, nɔto so?!)
• Pituitary ɔ hypothalamus sarcoidosis: Sarcoidosis na sik we de mek pɔsin inflamɛns.

Di tin dɛn we kin apin we kin pwɛl di pituitary gland ɔ di haypothalamus

• Ɔpreshɔn: Kɔmplikɛshɔn dɛn we kin apin we dɛn de du ɔpreshɔn pan di bren (espɛshali ɔpreshɔn fɔ pul di pituitary adenomas).
• Radieshɔn tɛrapi: Dɛn kin yuz redyushɔn fɔ trit di kansa tritmɛnt dɛn we dɛn bin dɔn gɛt bifo ɔ di pituitary adenomas.
• Siriɔs ed injuri (Traumatik bren injuri - TBI):Tin dɛn lɛk motoka aksidɛnt, fɔdɔm, ɛn spɔt injuri.
• Pituitary apoplexy: Wantɛm we di pituitary gland tisu de pwɛl.

Di mɛrɛsin dɛn we nɔ kin apin so ɔltɛm

• εmokromatosis we de kכmכt na di bεlε: Dis na jεnεtik kכndyushכn. I kin mek di ayɛn we pasmak kam insay di blɔd. Dis kin pwɛl di pituitary gland.
• Baktriyal mɛningɔyt: Pan ɔl we i nɔ kin apin so ɔltɛm, haypopituitarism kin apin as kɔmplikeshɔn fɔ baktriyal mɛningɔyt.
• jεnεtik mכtεshכn: Sכm jεnεtik kכndyushכn dεm we nכ kin apin kin mek di pituitary hכmon dεm nכ de wok fayn.

Wetin na di tin dɛn we kin mek pɔsin gɛt dis sik?

Dɛn kɔndishɔn ɔ tin ya we kin apin kin bi risk factor fɔ hypopituitarism:

• Bikɔs dɛn bin dɔn gɛt kansa ɛn redyushɔn tritmɛnt dɛn bifo tɛm .
• Hɛd ɔ bren injuri: Bitwin 27% ɛn 32% pan di pipul dɛm we dɔn gɛt traumatik ed injuri (TBI) kin gɛt hypopituitarism.
• Sikl sɛl anemia: Dis sik kin mek yu nɔ gɛt bɛtɛ ɔmon na di pituitary.
• Tayp 1 dayabitis: Di damej pan di nerves ɛn blɔd vesel dɛm wae de kam bikɔs ɔf tayp 1 dayabitis wae nɔr de kɔntrol kin mek dis sik.
• Bεlε εn bכn pikin: If yu bכdi bכku bכku wan afta yu bכn, i kin pwεl di pituitary gland. Dɛn kɔl dis sik we dɛn kɔl Sheehan syndrome .

Sɔm prɔblɛm dɛn we kin apin

di כmon dεm we de kam wit di haypopituitarism kin mek כda kכndyushכn dεm de divεlכp. Dɛn tin ya kin difrɛn difrɛn wan bay di ɔmon we nɔ de. Na sɔm ɛgzampul dɛn ya:

• If yu nɔ gɛt GH (growth hormone) i kin mek yu fat , yu gɛt bɔku kɔlɔstrel , ɛn i kin mek yu gɛt mɛtabolik sindrom .
• we uman dεn nכ gεt εstrojen כmon dεm (biכs fכ FSH nכ de) i kin mek uman dεn gεt כstioporosis ( di bon dεm we de tכn).
• If yu nɔ gɛt ACTH, dat kin mek yu gɛt adrenal kraysis , we na imejensi we kin mek yu layf de pan denja.

Us tɛst dɛn kin du fɔ no dis sik?

Yu dɔktɔ kin ɔda ɛni wan pan dɛn tɛst ya fɔ no if yu gɛt haypopituitarism:

• Blɔd tɛst fɔ no di ɔmon lɛvɛl: Dipen pan yu sik, yu dɔktɔ kin ɔda fɔ du blɔd tɛst fɔ no difrɛn ɔmon lɛvɛl.
• Tεst dεm fכ stimulashכn כmon: Insay dis tεst, yu dכkta go gi yu mεdisin fכ stimulate yu pituitary gland fכ rilis di כmon we dεn de tεst. Dɔn, dɛn kin tek blɔd sɛmpul ɛn sɛn am na lɛb fɔ mek dɛn tɛst am.
• Insulin tolerance test: Dis kin no if yu grɔj ɔmon (GH) ɛn ACTH nɔ de.
• Osmolality test fכ blכd εn urine: Dis de tεst fכ antidiuretic hormone (ADH) dεficiency.
• MRI (Magnetic Resonance Imaging) Scan: MRI skan de tek ditayla pikchɔ dɛn fɔ di insay pat pan yu bɔdi. Dɛn kin tek MRI skan na di bren as di bɛst we fɔ fɛn di pituitary tumor dɛn we kin mek pɔsin gɛt hypopituitarism.
• Bren CT (Computed Tomography) scan: Dɛn kin yuz dis tɛst fɔ si if na bren tumor ɔ pituitary adenoma de we de mek dis sik.

Aw dɛn kin trit di sik we dɛn kɔl hypopituitarism?

Pan ɔl we no mɛrɛsin nɔ de, dɛn kin trit am . Di tritmɛnt dipen pan us ɔmon dɛn we nɔ de ɛn wetin de mek yu gɛt dis sik . Yu mɛdikal tim go ɛp yu fɔ mek wan tritmɛnt plan we go bɛtɛ fɔ yu. Di tritmɛnt dɛn we dɛn kin gɛt na:

• כmon riplesmεnt tεrapi: Di ​​gol fכ dis na fכ mek di pituitary hכmon dεm we dεn dכn dכn kam bak to nכmal lεvεl. Bɔku tɛm, yu fɔ tek mɛrɛsin fɔ di res ɔf yu layf.
• Ɔpreshɔn: Pipul dɛn we gɛt pituitary adenomas kin nid ɔpreshɔn fɔ pul dɛn.
• Rεdyushכn tεrapi: Rεdyushכn tεrapi kin εp fכ shrink pituitary adenomas.

Yu dɔktɔ kin tɛl yu bak fɔ kɛr yu mɛdikal ID kad ɔ breslɛt wit yu ɔltɛm, if ɛnitin apin.

Wetin na di prɔgnosis fɔ hypopituitarism?

Di we aw pipul dɛn kin si tin kin difrɛn, i kin dipen pan dɛn tin ya:

• Yu ej we yu simptom bigin .
• Di rizin fɔ di tin we apin to yu .
• Aw di ɔmon dɛn we de dɔŋ kin afɛkt.
• Aw yu bɔdi kin biev we dɛn gɛt tritmɛnt .

Bɔrku pipul dɛm wae gɛt hypopituitarism de liv wɛl bɔdi layf. Bɔt if di pituitary damej fɔ lɔng tɛm, di layf we pɔsin kin liv kin shɔt smɔl pas di wan we pɔsin we gɛt di sem ej we nɔ gɛt dis sik kin liv. Bɔt bɔku tɛm, dɛn nɔ kin ridyus di layf we dɛn kin liv fɔ di wan dɛn we de fala di rayt tritmɛnt plan .

Wetin fɔ du if ɛnitin apin we nɔ izi fɔ du? If di haypopituitarism kam wantɛm wantɛm, i bad bad wan, ɛn dɛn nɔ trit am, i kin bi mɛdikal imejensi ɛn ivin mek pɔsin day. So if yu notis sɔm sayn dɛn, go to dɔktɔ wantɛm wantɛm.

Ustɛm a fɔ go to dɔktɔ?

Bɔku tɛm, di haypopituitarism kin nid fɔ tek tɛm wach di ɔmon dɛn we dɛn afɛkt fɔ ɔl dɛn layf . Si yu dɔktɔ ɔltɛm fɔ mek shɔ se yu tritmɛnt plan de wok.If yu gɛt nyu ɔr wɔri sayn dɛm, kɔl yu dɔktɔ kwik kwik wan.

Us kwɛstyɔn dɛn a fɔ aks mi dɔktɔ?

If dɛn no se yu gɛt hypopituitarism, yu kin aks yu dɔktɔ dɛn kwɛstyɔn ya:

• Us kayn hypopituitarism a gɛt?
• Us ɔmon dɛn we nɔ bɔku na mi?
• Wetin na di rizin fɔ dis?
• Us tritmɛnt opshɔn dɛn a gɛt?
• Ɛni bad tin de we kin apin to mi we a de trit mi?
• Aw lɔng a nid fɔ tek di mɛrɛsin?
• Dis go afɛkt di we aw a de bɔn pikin?
• Dis go afɛkt mi bɛlɛ?
• Dis kin apin to mi pikin dɛn bak?

Fɔ dɔn, mɛmba (Take-Home Message) .

Nyu diagnosis kin mek yu frayd, bɔt nɔr frayd fɔ aks yu dɔktɔ kwɛstyɔn bɔt hypopituitarism. Bɔku tɛm, i nid fɔ gɛt tritmɛnt fɔ ɔl yu layf ɛn fɔ wach di ɔmon dɛn. Na dat mek i impɔtant fɔ go to yu dɔktɔ ɔltɛm. If yu gɛt ɛni nyu ɔr wɔri sayn, kɔl yu dɔktɔ. Dɛn de de fɔ ɛp yu. If yu de manej yu fayn fayn wan, yu go ebul fɔ liv yu layf we gɛt wɛlbɔdi ɛn we de wok tranga wan.

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