Yu de fil bad? Yu an ɛn fut dɛn de go swɛ? Dis kin bi Inklushɔn Bɔdi Mayosaytis (IBM)!

Sɔntɛnde, yu kin fil lɛk se i nɔ kin izi fɔ yu fɔ ol tin, fɔ bɔtin bɔtin, ɔ ivin fɔ waka? Yu kin de tink se, "O, dis na jɔs sɔntin we kin apin we yu dɔn ol." Bɔt sɔntɛnde, dɛn tin ya nɔ kin so simpul. Tide, wi go tɔk bɔt wan rare bɔt rili impɔtant kɔndishɔn we wi fɔ no bɔt. dat dεn kכl am `Inklushכn Bכdi Myositis`, we dεn kכl bak `(IBM)` fכ sכt.

Wetin na `Inklushɔn Bɔdi Mayosaytis (IBM)`? Lɛ wi ɔndastand am simpul wan!

Fɔ tɔk am simpul wan, `Inclusion Body Myositis` na wan sik we de mek yu mɔsul dɛn wik smɔl smɔl, bɔt i nɔ de mek yu fil bɔku pen. I kin stat afta yu ol 50. Tink bɔt am, yu kin gɛt prɔblɛm fɔ `pinch` sɔntin we smɔl, i kin gɛt prɔblɛm fɔ `grap` sɔntin, ɔ ivin trip ɛn fɔdɔm we yu jɔs de waka. Dis na di fɔs sayn dɛm wae yu kin notis.

dis kכndyushכn we dεn kכl `IBM` de divεlכp sכmtεm sכmtεm ova plεnti ia. I nɔto tin we kin mek pɔsin in layf de pan denja. Dis min se i nɔ go kil yu. Bɔt as tɛm de go, i kin mek i nɔ izi fɔ du tin dɛn we pɔsin kin du ɛvride, ɛn dis kin mek pɔsin gɛt sɔm kayn disabled. Sɔntɛnde, na wan say nɔmɔ na yu bɔdi kin afɛkt mɔ. Na lɛk af pan pipul dɛm wae gɛt dis sik kin gɛt prɔblɛm bak fɔ swɛla.

I sɔri fɔ no se, no mɛrɛsin nɔ de fɔ IBM yet. Bɔt nɔ wɔri! Fyzikal tritmɛnt kin ɛp yu fɔ mek yu mɔsul dɛn kɔntinyu fɔ gɛt trɛnk fɔ lɔng tɛm.

Aw kɔmɔn dis `IBM` sityueshɔn?

Inklushɔn Bɔdi Mayosaytis na wan sik we de pan wan grup we gɛt sik dɛn we de mek di mɔsul dɛn wik we dɛn kɔl mayopathies. Mayopathies na sik dɛm wae de atak ɛn wik yu mɔsul fayv dɛm. Risach sho se IBM de afɛkt bitwin 5 ɛn 9 pan ɛvri milyɔn big pipul dɛm. I kin apin bak lɛk tri tɛm pan man dɛn pas uman dɛn (3: 1).

Wetin na di sayn dɛm fɔ `Inklushɔn Bɔdi Mayositis (IBM)`? Mek wi no di rayt tin!

di mכsul wik we IBM de mek de kam sכmtεm sכmtεm. Bɔku tɛm i kin bigin na di an ɛn fut dɛn. Yu kin notis fɔs se yu leg, yu shɔl, ɔ yu an, yu an, ɔ yu finga dɛn wik. Tink bɔt am dis we: i nɔ kin izi fɔ sɔm pipul dɛn fɔ bɔtin dɛn shirt, ɔ dɛn pen nɔ kin rayt fayn fayn wan. Ɔda wan dɛn kin gɛt prɔblɛm fɔ klaym stej, ɔ dɛn kin stɔp ɛn fɔdɔm we dɛn jɔs de waka.

As di sayn dɛm de wɔs smɔl smɔl, yu kin notis tin dɛm lɛk:

• Di mɔsul dɛn na di an, di leg, di sholda, di hip eria, di an, ɛn di finga dɛn kin wik smɔl smɔl. Imajin, yu nɔ go ebul fɔ es tin dɛn we yu bin de ebul fɔ es izi wan, ɛn yu gɛt prɔblɛm fɔ grap na chia.
• di mכsul dεm na di nεk כ εsophagus we wik. Dis kin mek i nɔ izi fɔ ol di ed tinap, i kin mek i nɔ izi fɔ swɛla it, ɛn i kin ivin mek di it stɔp.
• Di mɔsul atrofi de klia wan. Dis min se di mɔsul dɛn dɔn smɔl ɛn dɛn dɔn rili tan.
• Mild, frɛkuɛnt mɔsul pen (`myalgia`). Bɔt dis pen nɔ kin apin to ɔlman, ɛn ivin if i apin, i nɔ kin rili bad.

Fɔ ɛgzampul, imajin se yu gɛt wan padi we nem Sunil. I nɔ ebul fɔ ol in ti kɔp fayn fɔ sɔm tɛm naw, i de kɔntinyu fɔ slip na in an. We i go rid nyuspepa, in an kin fil lɛk se i de shek. Fɔs, i bin tink se na jɔs taya. Bɔt leta, i kam fɔ no se dis kin bi wan fɔs sayn fɔ `IBM`.

Wetin mek dis `Inklushɔn Bɔdi Mayositis (IBM)` kin apin? Wetin na di kɔz?

infakt, dis kכndyushכn we dεn kכl `Inklushכn Bכdi Mayositis` na `idiopathic`. Dat min se, i tan lɛk se i kin apin we nɔ gɛt ɛni patikyula rizin. lεk כda kayn `myositis`, insay dis kes, di inflameshn we de fכ lכng tεm na di mכsul dεm (`chronic inflammation`) na di men tin we de mek di mכsul dεm wik. Bɔt di wan dɛn we de stɔdi bɔt dis stil nɔ no bɛtɛ bɛtɛ wan wetin mek dis inflamɛns kin apin. Dɛn sɔspɛkt se i kin bi bikɔs ɔf prɔblɛm wit di imyun sistɛm (`autoimmune disease`) . Dat min se di sɛl dɛn we de protɛkt wi bɔdi kin mistek atak wi yon mɔsul sɛl dɛn.

`Inklushɔn bɔdi` dɛn gɛt fɔ du bak wit `IBM`. dis na abnכmal protin kכlכm dεm we de dכn insay di mכsul sεl dεm. Dɛn kin kam bikɔs ɔf wan vayrɔs infɛkshɔn, di sɛl dɛn we dɔn pwɛl, ɔ di chenj we di jɛnɛtiks chenj . dis `inklushכn bכdi` dεm dεn kin si dεm bak na nyurodijεnεraytiv sik dεm lεk `ALS`. Dɛn kin ambɔg di nɔmal wok we di sɛl dɛn de du.

Difrɛns bitwin `Inklushɔn Bɔdi Mayopati` ɛn `Inklushɔn Bɔdi Mayositis`

sכmtεm dεn kin kכl am bak `Inklushכn Bכdi Mayositis` `sporadik inklushכn bכdi mayosaytis (sIBM)`. `Sporadic` min se i kin apin randomly, ɔ witout wan patikyula kɔz. Dis na fɔ mek i difrɛn frɔm di sem kayn tin dɛn we pɔsin kin gɛt frɔm in mama ɛn papa. dεn kכl dεn wan dεm we de kכmכt frכm dεm `hεreditary inklushכn bכdi mayopathies (hIMB)`. we wi se `inklushכn bכdi mayopathies`, dεn tu kayn dεm ya de. Wi de tɔk naw bɔt di `sIBM` we kin apin randomly.

Aw dɛn kin no se dɛn gɛt `Inklushɔn Bɔdi Mayositis`? Us tɛst dɛn dɛn kin du?

Fɔ no if yu gɛt IBM, dɔktɔ go aks yu fɔs bɔt di sik dɛn we yu gɛt ɛn chɛk yu mɔsul dɛn. di simptom dεm fכ inklushכn bכdi mayosaytis kin lεk di wan dεm fכ כda kכndyushכn dεm, lεk polymyositis εn myasthenia gravis. Yu dɔktɔ go luk fɔ patikyula tin dɛn lɛk:

• Us mɔsul dɛn kin afɛkt? (e.g., na di finga ɔ di shɔl?)
• Na wan say nɔmɔ na di bɔdi kin afɛkt mɔ?
• Yu tink se di mɔsul dɛn we dɔn pwɛl klia wan?
• Aw ol yu bin ol we di sik bigin? (Bɔku tɛm afta dɛn dɔn ol 50 ia)

Dɔn, dɛn kin du sɔm tɛst fɔ ``rule out`` ɔda kɔndishɔn dɛn, lɛk:

• Creatine Kinase (CK) test: dis de mכsu di lεvεl fכ wan spεshal εnzym na di bכdi. dis `CK` lεvεl kin inkrεs we di mכsul dεm dεn dכn pwεl.
• Blɔd tɛst fɔ vayrɔs ɛn difrɛn ɔtoimyun sik dɛn.
• Ilɛktromayogram (EMG): Dis de mɛzhɔ di ilɛktrik wok we de na yu mɔsul dɛn. Dɛn kin du am bay we dɛn put smɔl smɔl nidul dɛn insay di mɔsul dɛn.
• Nεv Kכndukshכn Stɔdi (NCS): Dis de mכsu di spid we ilektrikal impuls de travul tru di nεv dεm (motor nerves) we de kכntro yu mכsul dεm.

Mɔsul bayɔpsi tɛst

di bεst we fכ kכnfכm if yu gεt inklushכn-bכdi mayosaytis na fכ tek sכm sכm tisu (bayopsi) frכm di mכsul we afekt. Wan patɔlɔjis go luk dis tisu sɛmpul ɔnda maykroskɔp. if yu gεt IBM, i go ebul fכ si inklushכn bכdi dεm (abnכmal protin kכlכmp, bכbul, כ vakuol) na di sεmpl.

Ɛni fayn tritmɛnt de fɔ `Inklushɔn Bɔdi Mayositis`?

כnכfכs, nכ ifektiv tritmεnt de fכ inklushכn bכdi mayosaytis. Nɔ lɛk ɔda inflammatory kɔndishɔn ɛn ɔtoimyun sik dɛm, i nɔ de ansa to kɔtikosterɔyd ɔ immunosuppressant drɔgs.

Bɔt nɔ giv ɔp fɔ op! I impɔtant fɔ mek yu mɔsul dɛn kɔntinyu fɔ gɛt trɛnk fɔ lɔng tɛm. Ɛksesaiz kin ɛp fɔ mek di mɔsul dɛn nɔ wik mɔ.

As de sik de go bifo ɛn i nɔr kin izi fɔ du tin wae yu kin du ɛvride, yu kin nid fɔ lan nyu we fɔ du tin. Dis na di say we ɔkupeshɔn tɛrapi kin ɛp. Fɔ ɛgzampul, dɛn kin tich yu aw fɔ yuz difrɛn difrɛn tin dɛn fɔ ɛp yu fɔ drɛs, it, ɛn rayt. Sɔm pipul dɛn kin nid bak fɔ lan aw fɔ yuz wilchia. If yu gɛt prɔblɛm fɔ swɛla, wan Speech-Language Pathologist (SLP) kin ɛp yu. Dɛn kin tich yu aw fɔ swɛla sef wan ɛn du ɛksɛsayz fɔ swɛla.

If a gɛt `Inklushɔn Bɔdi Mayositis`, wetin a fɔ ɛkspɛkt?

If yu get `IBM`, i go inkri sloslo. As a bin dɔn tɔk bifo tɛm, .Dis nɔ go afɛkt yu layf. Bɔt i kin afɛkt yu kwaliti layf. Yu go nid fɔ abop pan ɔda pipul dɛn ɔ lan nyu we dɛn fɔ du tin. Bɔrku pipul nɔr kin lɔs dɛn ebul fɔ waka ɔl, bɔt sɔm kin nid wilchia afta 10-15 ia.

Aw a kin tek kia ɔf misɛf we a de liv wit inklushɔn-bɔdi mayosaytis?

Yu go gɛt fɔ liv wit `Inclusion body myositis` fɔ lɔng tɛm, ɛn i kin bi smɔl chalenj as tɛm de go. Di bɛst we fɔ bia wit dis na fɔ mek plan fɔ lɔng tɛm fɔ kia fɔ yu bɔdi ɛn maynd wɛlbɔdi. Dat min se yu fɔ kɔntinyu fɔ praktis smɔl smɔl abit dɛn we de ɛp yu fɔ de wɛl. Fɔ ɛgzampul:

• Kɔntinyu fɔ du yu ɛksesaiz program. Yu kin de na fizik tɛrapi, ɔ yu kin dɔn chenj to wan program fɔ ɛksesaiz na os. If yu kɔntinyu fɔ du dis, dat go ɛp fɔ mek yu mɔsul dɛn strɔng as yu ebul.
• Fɔ fala ``wɛlnɛs layf.'' If yu it fayn, slip fayn, manej strɛs, ɛn kip yu impɔtant rilayshɔnship, yu go fil fayn ɔltogɛda.
• Join sɔpɔt grup dɛn. Yu kin gɛt bɔrku trɛnk na yu maynd ɛn prɛktikal advays frɔm ɔda pipul dɛm wae dɔn go tru ɔr de go tru di sem tin wae yu de du. I fayn bak fɔ fil lɛk "nɔto mi wan de go tru dis."
• Luk insay di adapteshɔn dɛn na os ɛn na wokples. Bɔrku tin de fɔ ɛp pipul dɛm fɔ muv ɛn ɛp pipul dɛm wae kin ɛp pipul dɛm wae gɛt disabled na dɛn bɔdi fɔ mek dɛn izi fɔ du ɛvride.
• Si yu dɔktɔ ɔltɛm. Stay in kɔntakt wit yu dɔktɔ. Tɛl yu dɔktɔ wantɛm wantɛm if yu notis ɛni nyu sayn, lɛk fɔ at fɔ swɛla, ɔ if wan sik we yu dɔn gɛt dɔn wɔs.
• Luk insay klinik trial dɛn. Risach pipul dɛm de luk ɔltɛm fɔ nyu tritmɛnt dɛm wae kin ɛp fɔ inklushɔn bɔdi mayosaytis. Yu kin tek pat bak pan dɛn prɔblɛm dɛn ya.

dis kכndyushכn we dεn kכl `Inklushכn bכdi myositis`, kin apin bכku tεm na midlayf, we nכ op de. Nɔbɔdi nɔ de tink se i go gɛt wan sik we nɔ go mɛn wantɛm wantɛm ɛn we de go bifo. E kin tranga smɔl fɔ bia wit ɛn ɛksplen to di wan dɛn we bisin bɔt yu, mɔ if dɛn nɔr dɔn yɛri bɔt dis sik bifo.

Bɔt mɛmba se dis na sik we de gro sloslo. So, bɔku tɛm de fɔ tink bɔt di chenj dɛn we de bifo ɛn mek ajɔstmɛnt dɛn akɔdin to dat. Nɔbɔdi nɔ go ebul fɔ tɔk fɔ tru aw dis go afɛkt yu. Bɔt,If yu gɛt op, bɔku tin dɛn de we yu kin du fɔ mek yu kɔntinyu fɔ gɛt wɛlbɔdi ɛn wɛl-at insay di ia dɛn we de kam.

Di impɔtant tin dɛn we wi nid fɔ mɛmba (Take-Home Message) .

Okay, so wi dɔn tɔk bɔku bɔt `Inklushɔn Bɔdi Mayositis (IBM)`. Fɔ dɔn, na di impɔtant tin dɛn we yu fɔ mɛmba:

• IBM na wan sik wae de sik wae de mek yu mכsul wik pasmak wae de kam mכst afta di ej 50. De pen nɔr kin at, bɔt as tɛm de go i kin afɛkt di tin dɛm wae yu kin du ɛvride.
• No mɛrɛsin nɔ de fɔ dis , bɔt fɔ trit yu bɔdi ɛn ɛksesaiz kin ɛp fɔ mek yu mɔsul dɛn kɔntinyu fɔ gɛt trɛnk fɔ lɔng tɛm.
• Di sayn dɛm kin bi we i nɔ kin izi fɔ ol tin, i kin stɔp we i de waka, ɛn i nɔ kin izi fɔ swɛla it .
• wi nכ no di εksakεt kכz (`idiopathic`), bכt i kin bi prכblεm wit di imyun sistεm.
• Dɛn kin jɔs kɔnfyus di sik bay we dɛn tek di mɔsul bayɔpsi.
• Dis nɔ de mek pɔsin in layf de pan denja , bɔt i kin afɛkt di kwaliti fɔ liv.
• I rili impɔtant fɔ mek yu kɔntinyu fɔ tink gud wan, fala di advays we dɔktɔ gi yu, ɛn gɛt di sɔpɔt we yu nid.

If yu ɔ pɔsin we yu sabi de gɛt dɛn kayn sik ya, i go fayn fɔ mek yu go to dɔktɔ. Mɛmba se nɔto yu wangren de, bɔku pipul dɛn de we go ebul fɔ ɛp!

` Mɔsul wik, IBM sik, fizik tɛrapi, mɔsul sik, ol pipul dɛn wɛlbɔdi, prɔblɛm fɔ swɛla, nyurolɔjik sik