Yu bɛlɛ sɛl dɛn dɔn chenj? Lɛ wi lan bɔt Intestinal Metaplasia!

Sɔntɛnde yu kin tink se we yu bɛlɛ de at ɔ yu gɛt gastritis , na nɔmal tin? Bɔku pipul dɛn kin du dat. Bɔt sɔmtɛm, tɛst wae dɛn kin du fɔ dɛn kayn sik ya kin sho sɔmtin wae wi nɔr go ivin tink bɔt. Na dat dɛn kɔl Intestinal Metaplasia, we na wan sik we yu nɔ kin si fɔs, bɔt i nid fɔ tek am na kɔna. Mek wi tok abaut dis simpul wan tide, okay?

So, wetin na dis (Intestinal Metaplasia)?

Fɔ tɔk am simpul wan, Intestinal Metaplasia na wan sik we di sɛl dɛn we de na yu ɔpa dijestiv trakt , dat na yu bɛlɛ ɔ yu εsophagus (di tiub we wi de swɛla it tru), de chenj. wetin kin apin na di sεl dεm na dεn εria dεm de bigin fכ lεk di sεl dεm na di intestinal. na dat mek i de gεt di "intestinal" pat, we min "lεk di intestinal dεm." We dɔktɔ dɛn si dis, i kin tan lɛk se dɛn dɔn chenj di layn na yu bɛlɛ ɔ yu εsophagus wit di layn na di insay.

Imajin dis: Yu gɛt wan patikyula kayn tayl na yu kichin wɔl. As tɛm de go, fɔ sɔm rizin, dɛn tayl dɛn de kin bigin fɔ chenj di sem kayn tayl dɛn we yu kin yuz na yu batrum. Na dat de apin na ya bak.

we dis kכndyushכn de apin na di εsophagus, dεn kin kכl am bak Barrett's esophagus . We i apin na di bɛlɛ, dɛn kin kɔl am bak gastric intestinal metaplasia .

Udat dɛn dis kayn tin kin afɛkt mɔ?

Sayɛnsman dɛn biliv se dis chenj we di sɛl dɛn chenj (mɛtaplasia) kin apin we di sɛl dɛn gɛt strɛs ɔ iritashɔn fɔ lɔng tɛm . Dis strɛs kin kɔmɔt frɔm difrɛn tin dɛn we de apin na di envayrɔmɛnt . Fɔ ɛgzampul:

• Fɔ smok
• Yuz rɔm

di men tin we de mek di intestinal Metaplasia ɔ Barrett’s esophagus na we di εsophagus de irita fɔ lɔng tɛm bikɔs ɔf di asid riflɔks . If yu dɔn gɛt sayn fɔ GERD (Gastroesophageal Reflux Disease) fɔ lɔng tɛm, smok, ɔ drink rɔm, yu go gɛt dis sik.

Na di ɔda say, di men tin we kin mek di intestinal mɛtaplasia na wan baktri infɛkshɔn we dɛn kɔl Helicobacter pylori . dis baktri de pwεl di protεktiv mכkus layn na di bεlε. כlso, wan kכndyushכn we dεn k כl כtoimyun mεtaplastik atrofik gεstritis na di kכz fכ intestinal mεtaplasia. insay dis, yu bכdi in yon imyun sistεm de atak di sεl dεm na di bεlε. Dis kin bi bak we pɔsin kin gɛt frɔm in mama ɛn papa.

Yu tink se Intestinal Metaplasia siriɔs?

Yɛs, dɛn kin tek dis sik as sɔntin we kin mek pɔsin gɛt kansa . Dis nɔto kansa , mɛmba. Bɔt, i kin bi wan step na di rod fɔ gɛt kansa. We di sɛl dɛn chenj wan tɛm, i kin izi fɔ mek dɛn chenj bak. If dɛn sɛl ya gɛt ɔda chenj we dɛn kɔl displasia , dɛn kin bi sɛl dɛn we nɔ gɛt kansa. Na da tɛm de nɔmɔ kansa kin kam.

Wetin na di stej dɛm fɔ Intestinal Metaplasia?

As di kכndyushכn (Intestinal Metaplasia) de kam tranga, i de go bifo to wan kכndyushכn we dεn kכl (dysplasia). I gɛt tu stej dɛn bak:

(Displasia we gɛt smɔl gred) .

insay dis, sכm sεl dεm de sho di fכs chenj dεm na di shep εn strכkchכ. Pan ɔl we dɛn kin tek dɛn sɛl ya as sɛl dɛn we nɔ gɛt kansa, i tan lɛk se dɛn nɔ de chenj kwik kwik wan. Yu dɔktɔ kin tɛl yu fɔ trit dis sik (low-grade dysplasia) bifo i wɔs.

(Displasia we gɛt ay gred) .

insay dis stej, yu kin si mכr komplεks chenj dεm na di sεl dεm. Bɔt i tan lɛk se dɛn nɔ de skata yet (invasive). Dis na wan step we de nia kansa. Yu dɔktɔ go tɛl yu fɔ trit dis sik (high-grade dysplasia) bifo i bi kansa.

Wetin na di tin dɛm wae kin mek pɔrsin gɛt (Intestinal Metaplasia)?

i tan lεk se intestinal mεtaplasia de apin as rεspכns to lכng tεm strεs na di tisu dεm na di bεlε כ εsophagus. Sayɛnsman dɛm nɔr kin ɔndastand gud gud wan wetin mek i kin de pan sɔm pipul dɛm ɛn nɔr kin de pan ɔda pipul dɛm. Bɔt i tan lɛk se na sɔm tin dɛn we dɛn jɔyn togɛda kin mek i apin:

• di nכmba f כ difrεn irita dεm we de afekt di tisu dεm.
• Di kayn we aw dɛn tin dɛn de we kin mek pɔsin fil bad.
• aw lכng (di tεm) di tisu dεn bin de εkspos to dεn strεs dεm de.
• Jεnεtik prεdispכzishכn – dis min se if pכsin na di famili gεt di kכndishכn (IM), כ bεlε כ εsophageal kεnsar.

Aw dɛn kin trit Intestinal Metaplasia?

Dɔktɔ dɛn kin trit dis sik bay we dɛn kin tray fɔ pul di tin dɛn we kin mek pɔsin vɛks we kin mek i vɛks, wit di op se dis go at ɔl mek di mɛtaplasia nɔ wɔs.

• Stɔp fɔ smok ɛn fɔ drink rɔm .
• Fɔ trit di asid riflɔks .
• Ɛradikeshɔn fɔ ( H. pylori ) infɛkshɔn.

We yu du dɛn tin ya, i de gi yu tisu dɛn chans fɔ wɛl frɔm di inflamɛns we nɔ de dɔn we de mek yu gɛt mɛtaplasia. If di sik go bifo to displasia, dɔktɔ dɛn kin se yu fɔ pul di tisu we gɛt di sik fɔ mek i nɔ tɔn to kansa.