Yu kin fil lɛk se yu de it wantɛm wantɛm? Yu kin sniz afta yu dɔn sniz? Ɔ yu kin gɛt rɛd rash na yu bɔdi afta sɔm tɛm afta yu dɔn it sɔm it dɛn? I go mɔs bi se dɛn tin ya dɔn apin to yusɛf. Bɔrku tɛm, dɛn kin kɔl de pɔrsin wae de biɛn dɛn diskɔmfɔt ya histamin. Tide, lɛ wi tɔk bɔt wetin na histamin, wetin mek i impɔtant fɔ wi bɔdi, ɛn wetin kin apin we i bɔku.
Wetin rili na histamin?
Fɔ tɔk am simpul wan, histamin na kemikal we kin apin na wi bɔdi bay wilful. I tan lɛk smɔl mɛsenja we de wok na wi bɔdi. I de stכr insay sכm sεl dεm na wi bכdi. i de mεntal stכr insay tu kayn sεl dεm we dεn k
כl mast sεl εn
basofil . Dɛn sɛl ya na pat pan wi imyun sistɛm, we na di sistɛm we de protɛkt wi frɔm sik dɛn. Tink bɔt am lɛk fɔt. We ɛnimi (fɔ ɛgzampul, wan jem ɔ pɔlin) kɔmɔt na do na dis fɔt, di gad dɛn lɛk dɛn mast sɛl ya kin yuz wan wɛpɔn we dɛn kɔl histamin fɔ bigin di fɛt. Nɔto dat nɔmɔ, dis padi we dɛn kɔl histamin de ɛp wi bɛlɛ bak fɔ digest it ɛn fɔ mek sɔm bren wok.
Wetin mek dis histamin de kɔmɔt na wi bɔdi?
di men rizin we mek di histamin de kכmכt na di b
כdi na di alerji . Lɛ wi si aw i kin apin. 1.
Alɛji: Imajin se yu gɛt alɛji to dɔst. We yu go na ples usay dɔst de, dɛn dɔst patikyula dɛn de (we wi kɔl
alɛrgen ) kin go insay yu nos. afta dat di mast sεl dεm na wi bכdi de no dכst patikyula dεm ya as "εnεmi". Dɛn kin no dɛn ɛn bigin fɔ du tin agens dɛn. dis tεm, di histamin we de insay di mast sεl dεm de kכmכt wan wan. Lɛk bɔm we de bɔn. Dis histamin na in de mek di nos sniz, stכf, εn di yay dεm de it.
2.
Injuri ɔ Infɛkshɔn: We di bɔdi wund, di skin brok, ɔ wan jem kam insay, histamin de kɔmɔt. Histamin de ɛp fɔ mek di blɔd flɔ mɔ to di say we di wund de, i de briŋ di tin dɛn we nid ɛn di sɛl dɛn we de fɛt di jem fɔ ɛp fɔ mɛn di wund.
Wetin histamin de du to di bɔdi?
We di histamin kɔmɔt na di bɔdi, i kin travul go na difrɛn pat dɛn na wi bɔdi ɛn i kin du difrɛn tin dɛn.
- Blɔd vesel dɛn : Histamin de mek di smɔl smɔl blɔd vesel dɛn na wi bɔdi big. Dɛn kɔl dis vasodilashɔn . Dis kin mek mɔ blɔd kɔmɔt na dɛn. Dis na wae mek sɔmtɛm wae yu gɛt alɛji, yu skin kin tɔn rɛd ɛn yu kin fil wam. Dɔn bak, wata kin bigin fɔ lik kɔmɔt na di wɔl dɛn na di blɔd vesel dɛn. Dis kin mek yu swel (Swelling/ Edema ), yu nos kin rɔn , ɛn yu yay kin gɛt wata.
- di rεspiretכri sistεm : Histamin de mek di mכsul dεm na di lכng dεm kכnstrikt. Dɛn kɔl dis brɔnkokonstrikshɔn . Dis kin mek i nɔ izi fɔ blo ɛn fil se in chɛst tayt, mɔ pan pipul dɛn we gɛt asma .
- Skin: Histamin kin mek di nεv εnd dεm na di skin εn mek i it/pruritus. i de rispansabl bak fכ mek di bכmp dεm we rεd, swεla (hayv/כtikaria) de apin na di skin.
- di dijestiv sistεm: We di mכsul dεm na di intestines kכntrakt, i kin mek yu bεlε kramp, nכs, vכmit, εn dayariya. Histamin de ɛp bak fɔ mek di bɛlɛ asid kɔmɔt.
- Nεv sεstem: Histamin de wok bak lεk nyurotransmitta na di bren. dis min se i de εp fכ kכri mεsej bitwin di nεv sεl dεm. Dis kin ɛp wi mɔ fɔ mek wi wek ɛn wach. (Na dat mek sɔm ol alɛji mɛrɛsin dɛn kin mek wi slip, bikɔs dɛn kin ridyus di wok we histamin de du na di bren bak.)
Wetin na di sayn dɛm we de sho se di histamin de bɔku?
Di sayn dɛm fɔ di histamin ɔvalɔd kin difrɛn frɔm wan pɔsin to ɔda pɔsin, i dipen pan aw bɔku histamin bin kɔmɔt ɛn us ɔgan sistɛm bin afɛkt mɔ.
- Di sayn dɛn we pɔsin kin si na di skin:
- Skin de rɛd, i de it
- Ekzema, we gɛt rash
- Ɔtikaria/Hayv: Na di say dɛn we de na di skin kin kam wantɛm wantɛm, we kin rɛd, we kin swel, ɛn we kin it bad bad wan.
- Nos ɛn trot simptom dɛm:
- Fɔ sniz
- Raynɔria ɔ nasal kɔnjɛshɔn
- Nos, trot, ɛn palata we de it
- Kɔf
- Swel na di trot, chenj na yu vɔys
- Di sayn dɛm we gɛt fɔ du wit di yay:
- Rɛd, yay dɛn we de it
- Kray wata we de kɔmɔt na di yay
- Di aylid dɛn we de swel
- Di sayn dɛm we gɛt fɔ du wit di lɔng:
- I nɔ izi fɔ blo, yu nɔ de blo fayn
- Fɔ fil se yu chɛst tayt
- Wiz (wistling) we yu de blo
- If yu gɛt asma, na asma exacerbation
- Di simptom dɛm we gɛt fɔ du wit di dijestiv sistɛm:
- Nɔs, fɔ vɔmit
- Bɛlɛ de pen, we yu de blo
- Rɔnbɛlɛ
- Ɔda tin dɛn we dɛn kin du:
- Ɛd we de at (ed we de at) .
- Diziz we pɔsin kin gɛt
- Lɔw blɔd prɛshɔn (especially if i gɛt siriɔs kes dɛm) .
Imajin se yu padi Sugath bin it sɔm shrimps. Insay af awa, in wan ol bɔdi bin de it ɛn i bin gɛt wan rɛd rash. I nɔ bin izi fɔ am fɔ blo. Dis kin bi bikɔs Sugath in bɔdi bin pul bɔku histamin wantɛm wantɛm fɔ ansa di shrimps.
Di kɔndishɔn we denja pas ɔl: Anafylaksis
Dis na
di alɛji we kin rili bad ɛn we kin mek pɔsin in layf de pan denja fɔ alɛji fɔ histamin. Dɛn kɔl dis
anafilaksis . insay dis, bכku histamin de kכmכt na di bכdi wan tεm. Dis kin apin insay sɔm minit.
Di men sayn dɛm fɔ anafilaksis na:- I nɔ kin izi fɔ yu fɔ blo (di say we di briz kin blo bikɔs di trot ɛn di tɔŋ kin swel) .
- Diziz, fil fɔ fil fɔdɔm
- Di at we de blo
- Di blɔd prɛshɔn we de go dɔŋ wantɛm wantɛm
- Kɔnfyus
- Blu ɔ pale skin
If yu si ɛni wan pan dɛn sayn ya, na mɛdikal imejensi. Dɛn fɔ kɛr yu go na ɔspitul wantɛm wantɛm. If yu delay di tritmɛnt, dat kin mek yu layf de pan denja. Di fɔs tritmɛnt we dɛn kin gi pan dɛn kayn tin ya na fɔ injɛkshɔn
wit adrenaline (Adrenaline/Epinephrine) .
Aw fɔ kɔntrol di tin dɛn we histamin kin du?
Laki, wi gɛt we fɔ kɔntrol dɛn diskɔmfɔt ya we histamin kin kam wit. 1.
Antihistamines: Dis na di men kayn mɛrɛsin. dis mεdikeshכn dεm de blכk di sayt dεm we histamin de tay (dεn kכl dεm
histamin rεsεpכta dεm) . Dis kin mek histamin nɔ gɛt in ɛfɛkt.
- Fɔs jɛnɛreshɔn antihistamin: Dɛn kin mek sɔm pipul dɛn slip (e.g., klorofeniramin, difenhaydramin). So, yu fɔ tek tɛm we yu de tek dɛn na nɛt ɔ we yu de du wok dɛn lɛk fɔ drayv.
- Sɛkɔn jɛnɛreshɔn antihistamin: Dɛn wan ya nɔ kin slip bɛtɛ (e.g., Loratadine, Cetirizine, Fexofenadine). I bɛtɛ fɔ yuz dɛn insay di de.
Dɔktɔ go disayd us antihistamine fayn fɔ yu ɛn aw lɔng yu nid fɔ tek am. 2.
Mast sel stεbyulayz dεm:Dɛn mɛrɛsin ya de wok bay we dɛn de blok di histamin we de kɔmɔt na di mast sɛl dɛn. (Ɛgzampul: Kromolin sɔdiɔm). Dɛn tin ya kin kam as nos sprɛy ɛn ay drɔp. 3.
Kɔtikosterɔyd: Dɛn wan ya na pawaful mɛrɛsin dɛn we de ridyus di inflamɛns. Sɔntɛnde, dɛn kin yuse dɛn fɔ shɔt tɛm fɔ kɔntrol asma pan siriɔs alɛji. 4.
Fɔ avɔyd tin dɛn we kin mek yu nɔ fil fayn: If yu no wetin yu gɛt alɛji to, i go fayn fɔ avɔyd dɛn tin dɛn de as yu ebul. Fɔ ɛgzampul, if yu gɛt alɛji fɔ dɔst, yu kin du tin dɛn lɛk fɔ kip yu os klin ɛn wɛr mask we yu de go na do insay di sizin we di pɔlin de du.
Wetin na di Histamine Intolerance?
Dis difrɛn smɔl frɔm alɛji. Histamine intolerance na we wi bɔdi nɔ ebul fɔ brok histamine fayn fayn wan frɔm it ɔ frɔm di amount of histamine we de mek insay di bɔdi. di men rizin fכ dis na di dכn pan di εnzym we dεn kכl
Diamine Oxidase (DAO) . If na so i bi, di sem sayn dɛm we yu kin gɛt we yu gɛt alɛji (it, ed we de at, bɛlɛ prɔblɛm) kin apin. Bɔt dis kin apin we yu it it dɛn we gɛt bɔku histamin (e.g., chiz we dɔn ol, it dɛn we dɔn fɛmɛnt, wayn, sɔm vɛjitebul ɛn frut dɛn). If yu gɛt ɛni dawt bɔt dis, i go fayn fɔ mek yu go to dɔktɔ ɛn tɔk to dɛn.
Ustɛm yu fɔ go to dɔktɔ?
Bɔku tɛm, i nɔ bad fɔ bay wan antihistamin frɔm famasi fɔ smɔl smɔl alɛji simptom dɛm. Bɔt, if dɛn kayn tin ya apin, yu fɔ rili go to dɔktɔ:
- If yu kin gɛt siriɔs alɛji bɔku tɛm.
- If dɛn nɔ de kɔntrol di sik dɛn bay we dɛn de tek mɛrɛsin ɔltɛm.
- If yu fil se i nɔ izi fɔ blo ɔ yu chɛst tayt.
- If yu gɛt ɛni wan pan di sayn dɛm fɔ anafylaksis (dis na imejensi!).
- If yu wan fɔ no di rayt tin we yu gɛt alɛji to ( alɛji tɛst de fɔ dat).
- If pɔsin de saspek se i nɔ de tek histamin.
Dɔktɔ kin ebul fɔ no aw yu sik kɔrɛkt wan ɛn gi yu di bɛst tritmɛnt ɛn advays we yu nid.
Fɔ dɔn, tin dɛn fɔ mɛmba (Take-Home Message) .
So, pan ɔl we histamin na impɔtant kemikal fɔ wi bɔdi, sɔntɛnde i kin mek wi gɛt prɔblɛm smɔl.
- Histamin de ple impɔtant pat pan alɛji, ɛn i de ɛp bak fɔ mek wund wɛl ɛn fɔ mek di bɛlɛ wok fayn.
- Tin dɛm lɛk fɔ sniz, it we yu skin de it, ayv, ɛn we yu nɔs de rɔtin kin bi bikɔs ɔf histamin.
- Anafylaksis na di sik we denja pas ɔl we histamin kin kam wit. Na mɛdikal imejensi we nid fɔ gɛt tritmɛnt kwik kwik wan.
- Antihistamines na di men mɛrɛsin dɛm wae de kɔntrol di ifɛkt dɛm wae histamine gɛt.
- If yu gɛt alɛji ɔltɛm ɔ yu gɛt siriɔs alɛji, mek shɔ se yu go to dɔktɔ.
Natin nɔ de fɔ wɔri bɔt. Bɔrku pan dɛn tin ya we gɛt fɔ du wit histamin kin bi saksesful wan. Di tin we impɔtant pas ɔl na fɔ pe atɛnshɔn to yu bɔdi ɛn aks fɔ di rayt dɔktɔ we nid de.
histamin, alɛji, alɛji riakshɔn, antihistamin, anafylaksis, ɔtikaria, asma, அல்ஜி, அல்ஜி
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