Glioma: Wi fɔ no dɛn tin ya bifo wi panik bɔt bren kansa?

Di wɔd ‘bren tumor’ ɔ ‘bren cancer’ de mek yu shek, nɔto so? Na wɔd we rili de mek pɔsin fred. Bɔt we wi no ɔl dɛn tin ya gud gud wan, wi kin ridyus da fred de bad bad wan. Tide wi de tɔk bɔt wan kayn kansa we dɛn kɔl glioma, we kin apin na di bren ɛn spɛshal kɔd. Lɛ wi si wetin i rili bi, wetin mek i kin kam, wetin na di sayn dɛm, ɛn us tritmɛnt dɛn de.

Wetin rili na Glioma?

Fɔ tɔk am simpul wan, glioma na jɛnɛral nem fɔ wan grup we gɛt kansa we de bigin na di ‘glial sɛl dɛn’ na wi bren ɛn spɛnal kɔd. dis glial sel dεm na wan rili imכtant kayn sεl we de sכpכt, protεkt, εn gi wi nεv sεl dεm. So, glioma de fכm we dεn sεl dεm ya bigin fכ gro we dεn nכ de kכntrכl.

De sayn dɛm, prɔgnosis, ɛn tritmɛnt fɔ dis kayn kansa kin difrɛn frɔm wan pɔrsin to ɔda pɔrsin. Dis dipen pan yu ej, di kayn kansa, di jεnεtik mak dεm (bayomak) we i gεt, εn usay di tכmכro de na di bren. sכm kayn glioma dεm de gro kwik kwik wan εn i de spre insay nכmal bren tisu. We dis kin apin, i kin rili at fɔ pul am kpatakpata wit ɔpreshɔn, ɛn sɔntɛnde i nɔ kin pɔsibul atɔl.

Glioblastomas na di kayn kansa bren tכmכro we kin kכmכn pan big pipul dεm. Dɛn kin apin mɔ pan pipul dɛn we dɔn ol ɛn dɛn kin apin smɔl pan man dɛn.

Wetin na di risk factor dɛm wae kin mek dɛn tin ya de divɛlɔp?

Dis na prɔblɛm we bɔku pipul dɛn gɛt. sεvεra mεjכr risk fכs dεm dεn dכn no we de kכntribyut fכ divεlכpmεnt fכ glioma.

• Di prɛviɔs rɛdyushɔn tɛrapi: Di ​​prɛviɔs rɛdyushɔn tɛrapi to di bren na risk factor fɔ divɛlɔp agresiv kayn gliomas.
• Injury na ed: Dɛn kin tek ed trauma bak as risk factor to sɔm mak.
• Jɛnɛtik kɔndishɔn: Pan ɔl we sɔm jɛnɛtik kɔndishɔn dɛn kin mek pikin dɛn gɛt dis kansa, i nɔ kin apin so ɔltɛm pan big pipul dɛn.

Men kayn ɛn gred dɛm fɔ glioma

Glioma na wan kayn kansa we dɛn kin klas bay di kayn glial sɛl we i kɔmɔt frɔm ɛn aw i de gro fast. fכ simpul tεm dεm, dεn kin sheb am to tu men tכp dεm: "slow-growing" (low-grade) εn "fast-growing" (high-grade). Lɛ wi luk sɔm pan di men kayn dɛn.

Kansa gred ɛn jenɛtik mak dɛn

Di World Health Organization (WHO) klasification, dɛn kin gred dɛn kansa ya bay aw di kansa sɛl dɛn de luk ɔnda maykroskɔp ɛn dɛn jenɛtik prɔfayl. di prεsεns fכ sכm jεnεtik chenj dεm (e.g., `IDH mutation`, `1p/19q co-deletion`) de sho se di kεnsar de rεspכnd fayn to sכm tritmεnt dεm. Dɛn tin ya na kɔmpleks tin dɛn, so yu dɔktɔ go ɛksplen dɛn tin ya to yu.

Yu gɛt dɛn sik ya bak?

di sayn dεm fכ glioma kin difrεn dipכnt pan usay di bren tכmכro de. Fɔ ɛgzampul, yu kin gɛt ed pen we difrɛn frɔm di nɔmal ed pen ɛn i kin tan lɛk se i de wɔs ɛvride. Ɔ yu kin gɛt sik we dɛn kɔl seizure wantɛm wantɛm. Dis na di men sayn dɛm.

Di sayn dɛm we kin apin mɔs:

• Ɛd we de at: Na lɛk af pan di pipul dɛn we gɛt kansa na dɛn bren kin gɛt dis sik.
• Seizures: I kin bigin fɔ sik wantɛm wantɛm fɔ no rizin.
• Memori lɔs: Fɔ fɔgɛt di tin dɛn we dɔn apin dis biɛn tɛm.
• di wikɛd tin na di bɔdi: di wan an ɔ leg kin swɛla, i nɔ kin ebul fɔ kɔntrol di mɔsul dɛn.
• Prɔblɛm dɛn we yu de si: yu nɔ de si fayn, yu de si yu tu tɛm.
• I nɔ izi fɔ tɔk: fɔ slɔr wɔd dɛn we yu de tɔk, nɔ ebul fɔ mɛmba di rayt wɔd.
• Pɔsin kin chenj: I kin chenj di we aw pɔsin de biev, lɛk fɔ vɛks wantɛm wantɛm ɔ fɔ mek i vɛks kwik kwik wan.

As di kansa de gro, dɛn sayn ya kin wɔs smɔl smɔl as i de pwɛl di bren sɛl dɛn, kɔmprɛs sɔm pat dɛn na di bren, ɛn mek di bren swel.

Aw dɔktɔ dɛn kin no bɔt dis? (Diagnosis) .

If dɛn tink se gɛt tumbu na di bren, di fɔs tin we di dɔktɔ go du na fɔ ɔda fɔ mek dɛn skan di bren.

1. Skan: Dɛn kin yuz `CT` skan ɔ `MRI` skan fɔ dis. Di `MRI` skan kin gɛt klia imej dɛn.

2. Bayopsi: If di skan kɔnfyus se tumbu de, dɛn kin tek smɔl pat pan am ɛn tɛst am fɔ no uskayn kansa i bi. Wi kin kɔl dis ‘bayɔpsi’. If dɛn de du ɔpreshɔn, dɛn kin tek dis pat di sem tɛm. if di tכmכro dip insay di bren εn dεn nכ kin כpεret am, dεn kin yuz spεshal we dεn kכl `stereotactic needle biopsy` fכ mek sכm sכm ol na di sכkul εn pas nidul tru am fכ gεt tisu sεmpl.

Wetin na di tritmɛnt dɛm fɔ dis?

Bɔku tritmɛnt dɛn de fɔ glioma. Di tritmɛnt we dɛn kin pik kin dipen pan di kayn, gred, usay i de, di jenɛtik mak dɛm (bayomak dɛm) fɔ di kansa, ɛn di pɔsin in ej ɛn ɔl in wɛlbɔdi.

• Ɔpreshɔn:Di men gol na fɔ pul di tumbu as sef wan as i pɔsibul. If yu pul bɔku pan di tɔŋ as yu ebul ɛn nɔ pwɛl di impɔtant tin dɛn we yu bren de du (we yu de tɔk, we yu de muv) i kin mek di sik nɔ bɔku ɛn kɔntrol di we aw di sik de skata.
• Radieshɔn Tɛrapi: Dɛn kin yuz ɛkstrem rayt we gɛt bɔku ɛnaji ɔ ɔda kayn raytin fɔ pwɛl ɛni kansa sɛl we lɛf.
• Kimotɛrapi: Fɔ gi drɔgs (we yu de yuz pils ɔ injɛkshɔn) we de stɔp di kansa sɛl dɛn fɔ gro.
• Targeted Therapy: Dɛn tin ya difrɛn frɔm di kemotɛrapi we dɛn kin gi ɔltɛm. Dis na di mכdan mכdan dεm we de tכk εn atak spεshal protin dεm כ jεnεtik mak dεm we de εp di kεnsar sεl dεm fכ gro.
• Alternating Electric-Field Therapy: Dis na nyu we fɔ trit pɔsin. Dɛn kin put ilɛktrɔd dɛn na di skel ɛn dɛn kin put ilɛktrik fil we nɔ gɛt bɛtɛ pawa, we kin pwɛl di kansa sɛl dɛn we nɔ kin ambɔg di nɔmal sɛl dɛn. Wan divays we dɛn kɔl ``Optune Gio`` de yuz fɔ dis.
• Sɔpɔtiv Tɛrapi: Tritmɛnt we dɛn kin gi fɔ kɔntrol di sik dɛn. Fɔ ɛgzampul, kɔtikosterɔyd fɔ ridyus di bren swel ɛn antikɔnvulsant fɔ kɔntrol di sik we pɔsin kin gɛt.
• Klinik Trayal: Risach we de tɛst if nyu tritmɛnt dɛn de wok ɛn sef. Sɔm pasɛnt dɛn kin ebul fɔ tek pat pan dɛn tin ya.

Di tritmɛnt bak kin difrɛn difrɛn wan bay di kayn kansa. Fɔ ɛgzampul, ɔpreshɔn na di men tritmɛnt fɔ low-grade astrocytoma. Bɔt di glioblastoma we gɛt ay gred nid fɔ gɛt ɔpreshɔn, redyushɔn tɛrapi, ɛn kemotɛrapi.