Yu gɛt wan tumbu we nɔ kin bɔku na yu nervɔs sistɛm? (Malignant Peripheral Nerve Sheath Tumor - MPNST) Lɛ wi lan bɔt am.

Yu dɔn ɛva fil wan swɛlin sɔmsay na yu bɔdi, sɔntɛm na yu an ɔ yu leg, we de gro smɔl smɔl? Dɛn lumps ya, we sɔntɛnde kin bigin smɔl lɛk pis ɛn gro big lɛk ɔrɛnj, na dɛn wi go tɔk bɔt tide. Dis na siriɔs tin, bɔt i nɔ kin apin so ɔltɛm. Dɛn kɔl am malignant peripheral nerve sheath tumor, ɔ MPNST fɔ shɔt.

Wetin na di malign pεrifεral nεv sεt tכmכro (MPNST)?

Fɔ tɔk am simpul wan, MPNST (Malignant Peripheral Nerve Sheath Tumor) na wan kansa tɔŋ we nɔ kin bɔku we kin de na di kɔva dɛn we de protɛkt (nerve sheaths) we de rawnd di nerv dɛn na yu bɔdi. Dɛn tin ya de pan wan kayn sɔft tisu sarkoma . Dɛn kin apin na yu peripheral nervous system . Tink bɔt am, yu kin gɛt dɛn tumbu ya na yu an ɛn yu leg. Nɔto dat nɔmɔ, sɔm tɛm dɛn kin kam bak na di bɛlɛ, bɛlɛ, ed, ɛn nɛk. Dɛn tumbu ya kin wɛl bay we dɛn du ɔpreshɔn pan dɛn. Bɔt wi fɔ mɛmba bak se sɔntɛnde dɛn tumbu ya kin kam bak .

Aw MPNST nɔ bɔku?

Dis na wan sik we kin rili, rili rare. Na lɛk wan pan ɛvri 100,000 pipul dɛn nɔmɔ dɛn kin no se gɛt dis malignant peripheral nerve sheath tumor (MPNST) ɛvri ia. Bɔrku tɛm e kin afɛkt pipul dɛm wae ol bitwin 30 ɛn 50 ia .

apat frכm dat, pipul dεm we gεt jεnεtik kכndyushכn we dεn kכl Nyurofibromatosis tayp 1 (NF1) kin gεt MPNST. Dɛn dɔn si se bitwin 25% ɛn 50% pan di pipul dɛm we gɛt MPNST gɛt NF1 bak .

in jεnarכl, MPNST kin divεlכp fכs pan pipul dεm we gεt NF1 pas pipul dεm we nכ gεt NF1. כlso, man dεm we gεt NF1 kin gεt MPNST sכmtεm pas di wan dεm we nכ gεt NF1.

Wetin na di sayn dɛm fɔ MPNST?

MPNST dεm kin divεlכp enisay along yu pεrifεral nεv dεm, bכt dεn kin afekt εria dεm lεk yu an εn leg dεm mכst. Sɔntɛnde dɛn kin kam bak na say dɛn lɛk yu bɛlɛ, yu chɛst, yu bɛlɛ, ɔ yu ed ɛn nɛk. Di sayn dɛm fɔ MPNST na:

• Wan lump we de gro sloslo ɔnda di skin. Dɛn lumps ya kin smɔl lɛk pis (lɛk 2 sɛntimita) ɔ big lɛk ɔrɛnj (lɛk 10 sɛntimita).
• Fɔ fil pen (especially if yu gɛt NF1).
• Fɔ mek pɔsin nɔ fil fayn (Paresthesia).
• Fɔ fil se yu an ɛn yu fut wik.

Wetin na di tin dɛn we kin mek pɔsin gɛt MPNST?

stכdi dεn sho se 50% pan di malignant pεrifεral nεv sεt tכmכro dεm na nyurofibromatosis tayp 1 (NF1) de kכz dεm.Dɛn kɔl di kɔndishɔn. Ɔda rizin dɛn kin bi:

• Radiation therapy: Na lɛk 10% pan di pipul dɛm wae gɛt MPNST dɔn gɛt redyushɔn tɛrapi fɔ ɔda sik dɛm.
• jεnεtik mכtεshכn: Risach pipul dεn dכn kam fכ no se bכku difrεn jεnεtik mכtεshכn dεm de we de mek nכmal nεv sεl dεm bi abnכmal sεl dεm, bכku bכku wan, εn fכm tכmכro.
• Sɔm kayn nyurofibroma: Pipul dɛn we gɛt plexiform nyurofibroma kin gɛt mɔ risk fɔ gɛt MPNST.

Aw dɛn kin no MPNST?

We yu go to dɔktɔ, i go fɔs du yu bɔdi ɛgzam ɛn aks bɔt yu jenɛral wɛlbɔdi. Dis go inklud fɔ aks bɔt yu mɛdikal histri, yu famili mɛdikal histri, ɛn ɛni sayn we yu go gɛt. Apat frɔm dat, dɛn kin du dɛn tin ya:

• Imej tɛst: Dɔktɔ dɛn kin du tɛst lɛk MRI (Magnetic Resonance Imaging) ɛn PET (Positron Emission Tomography) skan .
• Bayopsi: Dɔktɔ kin du bayɔpsi, tek wan tisu sɛmpul ɛn mek wan dɔktɔ we de stɔdi bɔt sik dɛn chɛk am ɔnda maykroskɔp .
• Jɛnɛtik tɛst: If yu gɛt bad bad peripheral nerve sheath tumor, yu dɔktɔ kin se yu fɔ du jenɛtik tɛst fɔ si if yu ɔ yu fambul we de nia yu gɛt nyurofibromatosis tayp 1 (NF1) ɔ ɔda kayn nerve sheath tumor , neurofibromatosis type 2 (Schwannomatosis) .

Wetin na di tritmɛnt dɛm fɔ MPNST?

Dɔktɔ dɛn kin du ɔpreshɔn fɔ pul wan bad bad peripheral nerve sheath tumor. Bɔt sɔm kes dɛn de we pɔsin nɔ kin ebul fɔ du ɔpreshɔn. Fɔ ɛgzampul:

• Big nat (nat 5 cm ɔ big pas dat).
• Tכmכro dεm we de mεtastas.
• di tכmכro dεm we de rili nia di kכmpleks nεv nεtwכk dεm kin pwεl we dεn de du di כpεrayshכn.

Insay dɛn kayn tin ya, dɔktɔ dɛn kin trit MPNST wit wan kɔmbayn ɔpreshɔn, kemotɛrapi , ɔ redyushɔn tɛrapi . Dɛn kin gi dɛn raytin tɛrapi bifo ɔ afta dɛn du di ɔpreshɔn.

Naw, di wan dɛn we de stɔdi bɔt dis de luk if dɛn kin yuz imyunotɛrapi ɔ di tritmɛnt we dɛn kin yuz fɔ mɛn pipul dɛn as nyu tritmɛnt. If yu gɛt malignant peripheral nerve sheath tumor, yu kin fit fɔ gɛt klinik trial we de tɛst nyu tritmɛnt dɛn.I go fayn fɔ mek yu tɔk to yu dɔktɔ bɔt aw fɔ tek pat.

Wetin na de prɔblɛm ɔr sayd ɛfɛkt wae kin kam wae pɔrsin gɛt tritmɛnt?

Di prɔblɛm dɛn we kin apin we dɛn de du di ɔpreshɔn na:

• Rispɔns to jenɛral anestezi.
• Blɔd we de kɔmɔt pasmak (ɛmoraji).
• Pen.
• Ska dɛn we dɛn kin du ɔpreshɔn pan.
• Infεkshכn fכ wund we dεn de du כpεrayshכn.

Tritmɛnt lɛk kemotɛrapi ɔ redyushɔn tɛrapi kin mek yu gɛt sayd ɛfɛkt lɛk:

• Rɔnbɛlɛ.
• Taya.
• Nɔs ɛn vɔmit.

Wetin na di prɔgnosis fɔ pɔsin we gɛt MPNST?

Prɔgnosis na aw yu mɛdikal tim tink se yu go tan lɛk afta yu dɔn fɔ gɛt tritmɛnt. insay di kes fכ MPNST, dis prכgnosis de ditarεmin bay sεvεra fכs tin dεm:

• NF1 stetכs: we dεn tכmכro dεm ya de divεlכp pan pipul dεm we gεt NF1, di prכgnosis fכ rεkכvεshכn kin sכmtεm lכs pas pipul dεm we nכ gεt NF1.
• Tumɔs gred: Di wan dɛn we de stɔdi bɔt di sik kin luk di sɛl dɛn ɔnda maykroskɔp ɛn kin klas di tumbu dɛn as ay gred ɔ lɔw gred . di tכmכro dεm we gεt hכy grεd gεt hכy chans fכ gεt kεnsar sεl dεm we de sheb kwik kwik wan εn spre.
• di tכmכro saiz: di MPNST tכmכro dεm kin big lεk 10 sεntimita. Bɔku tɛm, i nɔ kin izi fɔ pul big tumbu dɛn we dɛn de du ɔpreshɔn.
• Metastasis: If di tumbu dɔn skata to ɔda say dɛn frɔm usay i bigin, i kin at fɔ trit.

As yu si, bɔku tin dɛn de we kin afɛkt di we aw yu go gɛt wɛlbɔdi, ɛn nɔto ɔl dɛn tin ya kin apin to yu. So, i go fayn fɔ aks yu dɔktɔ fɔ no di rayt tin bɔt yu prɔblɛm. Bikɔs i no wetin de apin to yu, i kin gi yu di tin dɛn we yu nid.

Wetin na di sɔvayv rɛt fɔ MPNST?

di rεt fכ sכvayv na εstimat bay di εkspiriεns dεm fכ כda pipul dεm we bin gεt malignant pεrifεral nεv sεt tכmכro. Bikɔs dɛn tumbu ya nɔ kin bɔku, i nɔ kin izi fɔ mek masta sabi pipul dɛn gi di rayt rit. Akɔdin to di Nashɔnal Kɛnsa Instityut (US), bitwin 23% ɛn 69% pan di pipul dɛm we gɛt MPNST de alayv fayv ia afta dɛn dɔn no se dɛn gɛt am. Dat na big rɛnj, nɔto so? So i bɛtɛ fɔ aks yu dɔktɔ bɔt di tin we de apin to yu.

Aw a kin kia fɔ misɛf?

If yu gɛt malignant peripheral nerve sheath tumor, yu de gɛt kansa we nɔ kin bɔku we kin kam bak afta dɛn dɔn trit yu. Bɔku program dɛn de we go ɛp yu pan dis kayn tin:

• Paliativ kia:Insay palliativ kia, yu go wok wit wan tim we gɛt spɛshal trenin dɔktɔ dɛn we go ɛp yu fɔ manej di sayn dɛm fɔ MPNST ɛn di sayd ɛfɛkt dɛm we di tritmɛnt kin gɛt. Wetin pas dat, dɛn go gi yu saykilɔjik sɔpɔt bak.
• Program dɛm fɔ sev frɔm kansa: Kansa tan lɛk wan waka. Di program dɛm fɔ sev frɔm kansa de gayd yu frɔm di de we dɛn no se yu gɛt di sik, tru yu tritmɛnt, ɛn wetin fɔ du if di kansa kam bak.

Fɔs, we yu si am, wan malignant peripheral nerve sheath tumor (MPNST) na yu an ɔ yu leg kin tan lɛk wan lump we yu kin gɛt bad bad tin ɔ brus izi wan. Fɔ no se di lump na wan kayn kansa we nɔ kin bɔku ɛn i nid fɔ gɛt ɔpreshɔn, dat kin mek yu shɔk. E kin tranga fɔ tek in. If yu gɛt kwɛstyɔn bɔt yu sik ɔr wetin fɔ ɛkspɛkt, yu mɛdikal tim ɔndastand. Dɛn go gladi fɔ tek dɛn tɛm fɔ ansa yu kwɛstyɔn dɛn ɛn adrɛs ɛnitin we de mɔna yu.

Di mɛsej we pɔsin kin kɛr go na os frɔm dis atikul

Okay, so a op se yu gɛt sɔm ɔndastandin bɔt dis rare kansa kɔndishɔn we dɛn kɔl MPNST we wi tɔk bɔt tide. Mɛmba se dis na tin we nɔ kin apin so ɔltɛm. If yu gɛt ɛni ɔnusual lumps, pen, numbness, etc. na yu bɔdi we de kɔntinyu, definitely go to doctor and get advice. Di kwik we dɛn no am, na di mɔ i izi fɔ trit.

Di tin we impɔtant pas ɔl na dat, nɔto yu wangren de. Yu mɛdikal tim, yu fambul, ɛn padi dɛn ɔl de fɔ ɛp yu. Di tin we impɔtant pas ɔl na fɔ kɔntinyu fɔ strɔng ɛn fala yu dɔktɔ in advays.

` Malignant pεrifεral nεv sεt tכmכro, MPNST, nεv kεnsar, tכmכro, kεnsar, nyurofibromatosis, NF1, כpεrayshכn, rεdyushכn tεrapi, kεmothεrapi