Yu gɛt prɔblɛm wit yu blɔd pletlɛt? Lɛ wi lan bɔt di ‘May-Hegglin Anomaly’!

Yu don eva yehri boht di nem ‘May-Hegglin Anomaly’? Sɔntɛm nɔto so. Bikɔs dis na tin we nɔ kin apin so ɔltɛm, dat na, wan sik we pɔsin kin si we nɔ kin apin so ɔltɛm. Bɔt yu nɔ fɔ fred we yu yɛri dis nem? Tide, lɛ wi tɔk bɔt dis simpul wan, di we we yu go ɔndastand. Na bikɔs fɔ no bɔt dis kin rili impɔtant.

Wetin na dis ‘May-Hegglin Anomaly’?

Fɔ tɔk am simpul wan, May-Hegglin Anomaly na wan sik we kin kam bikɔs ɔf smɔl chenj na yu jin dɛm (wan jɛnɛtik muteshon). Dis kin mek yu bɔdi mek pletlɛt, we na smɔl smɔl blɔd sɛl dɛn we wi kin kɔl pletlɛt, we big smɔl ɛn we nɔ kin mek bɔku pas aw dɛn fɔ mek. dis dכn we di pletlεt dεm de dכn, dεn kכl am thrombocytopenia.

Naw yu go de wɔnda wetin kin apin to dɛn pletlɛt ya. Imajin se yu gɛt smɔl wund. Dɔn dɛn pletlɛt ya kin ɛp fɔ stɔp di blɔd. Dɛn kin mek blɔd klɔt ɛn stɔp di blɔd. So, pɔsin we gɛt di ‘May-Hegglin Anomaly’, bikɔs dɛn pletlɛt ya nɔ kin big ɛn dɛn kin smɔl, sɔntɛnde i kin brus ɔ blɔd izi wan pas nɔmal pɔsin. dis kayn blɔd (dat na, ``ɛmoraji'') kin bɔku bak afta dɛn dɔn du big ɔpreshɔn.

Bɔt na sɔmtin wae yu fɔ mɛmba: Bɔrku pipul dɛm wae gɛt dis sik nɔr kin sho ɛni sayn. Ɔ, i nɔ de kɔz ɛni big prɔblɛm. Bɔt, ilɛksɛf yu gɛt di sik ɔ yu nɔ gɛt di sik, i impɔtant fɔ no se yu gɛt May-Hegglin Anomaly. Dɔn yu ɛn yu dɔktɔ dɛn kin du di tin dɛn we yu nid fɔ protɛkt yusɛf frɔm aksidɛnt ɛn blɔd.

Tri men kwaliti dεm de we de sho di ‘May-Hegglin Anomaly’?

Yɛs, tri men tin dɛn de we dɔktɔ dɛn kin luk fɔ fɔ no dis sik kɔrɛkt wan. Dis na wetin wi de kɔl di ‘triad’. Dat min se, tri tin dɛn we gɛt fɔ du wit di kwaliti dɛn.

Dɛn na:

• fכ gεt big big pletlεt dεm we nכ nכmal: Wi kכl dis makrotrombosaytopenia.
• Di pletlet kɔnt we de go dɔŋ: Dis na di sik we wi bin dɔn tɔk bɔt bifo tɛm we dɛn kɔl trombocytopenia.
• Yu kin si smɔl smɔl tin dɛn we tan lɛk stik we dɛn kɔl Döhle bɔdi insay yu lukosayt dɛn, we na wan kayn wayt blɔd sɛl. Dɛn Döhle bɔdi ya spɛshal.

Dɔktɔ dɛn kin no difrɛns bitwin May-Hegglin Anomaly frɔm ɔda sik dɛn we kin afɛkt di pletlɛt dɛn bay we dɛn de luk fɔ dɛn tri kwaliti ya.

Aw dis sik kin kɔmɔn? Ɔ i nɔ kin apin so ɔltɛm?

Di ‘May-Hegglin Anomaly’ na wan sik we nɔ kin apin so ɔltɛm.Di ripɔt dɛn we dɛn dɔn sho se di wan dɛn we gɛt di sik dɔn pas 200 ɔlsay na di wɔl. Imajin aw dat nɔ kin apin so ɔltɛm! Bikɔs i nɔ kin apin so ɔltɛm, bɔku tɛm dɔktɔ dɛn kin dawt fɔs. Yu dɔktɔ kin nid fɔ pul sɔm ɔda tin dɛn we kin afɛkt yu pletlɛt bifo i kam fɔ no se yu gɛt May-Hegglin Anomaly.

Wetin na di sayn dɛm fɔ ‘May-Hegglin Anomaly’?

As wi bin dɔn tɔk, bɔrku pipul dɛm wae gɛt dis sik nɔr kin gɛt ɛni big big sayn. Dis na bikɔs dɛn gɛt bɔku pletlɛt dɛn na dɛn bɔdi fɔ mek dɛn nɔ blɔd pasmak. Bɔt if yu gɛt sɔm sayn dɛn, dɛn go rili dipen pan aw yu pletlɛt dɛn nɔ bɔku.

Dis na di sayn dɛm wae yu kin si in jɛnɛral:

• Brus ɛn blɔd izi wan. Fɔ tɔn blu ivin afta yu gɛt smɔl bɔmp, ɔ tek sɔm tɛm fɔ stɔp fɔ blɔd ivin we yu kɔt am smɔl.
• Blɔd we de kɔmɔt na yu nos ɔltɛm. Sɔm pipul dɛn kin kɔl dis `(epistaxis)`.
• Di blɔd we de kɔmɔt na di gɔm. Dis kin apin we yu de brus yu tit.
• Fɔ uman, blɔd we de kɔmɔt pasmak we dɛn de gɛt mɔnt. Dɛn kin kɔl dis bak `(menorrhagia)`.
• Rɛd, pepul, ɔ brawn spat dɛn na di skin. Dɛn kɔl dɛn tin ya ``purpura''.
• Bɔku blɔd we de kɔmɔt afta dɛn dɔn du di ɔpreshɔn, we dɛn pul di tit, ɔ afta dɛn dɔn bɔn pikin.

De impɔtant tin na, nɔr frayd fɔ tink se yu gɛt May-Hegglin Anomaly jɔs bikɔs yu gɛt wan ɔ tu pan dɛn sik ya. Dɛn tin ya kin kam bak bikɔs ɔf ɔda tin dɛn. So i bɛtɛ fɔ mek yu go to dɔktɔ fɔ advays.

Wetin kin mek di ‘May-Hegglin Anomaly’ de?

May-Hegglin Anomaly na wan jenɛtik kɔndishɔn we yu kin gɛt frɔm wan pan yu mama ɛn papa. wi gεt wan jin we dεn kכl `MYH9` na wi bכdi. na ya sכm sכm chenj we de apin na dis `MYH9` jin, dat na, wan `mכtεshכn`, we na di men kכz fכ dis. biכs fכ dis jin mכtεshכn, prכblεm de kכmכt pan di we aw di pletlεt dεm de fכm. Na dat mek dɛn kin fɔm insay big big shep dɛn we nɔmal. כlso, bikoz fכ dis `MYH9` jin mכtεshכn, di nכmba fכ di pletlet dεm de rεdכks bak. Na dat mek yu kin brus ɛn blɔd izi wan.

wi kכl di inhεritεns patεn fכ May-Hegglin Anomaly wan כtosom dכminant patεn. dis min se yu nכ nid fכ gεt wan kכpi fכ di mutated MYH9 jin fכ gεt di kכndyushכn. Dis min se if yu mama ɔ papa gɛt di muteshon, yu gɛt 50% chans fɔ gɛt am.

Aw fɔ no di May-Hegglin Anomaly?

Bɔrku tɛm, dɛn kin no di May-Hegglin Anomaly bay we dɛn de du blɔd tɛst fɔ sɔm ɔda rizin. Dɔktɔ dɛn kin sɔprayz se na we di blɔd tɛst rizɔlt sho se di pletlɛt dɛn nɔ bɔku ɔ di pletlɛt dɛn bɔku. Fɔ ɛgzampul, dɛn kin no dis ivin we dɛn de du blɔd tɛst ɔltɛm we uman gɛt bɛlɛ.

Bɔku tɛst dɛn de we yu kin yuz fɔ no if yu gɛt di May-Hegglin Anomaly:

• Kɔmplit Blɔd Kɔnt (CBC): Dis ``(CBC)`` tɛst kin chɛk if yu pletlɛt kɔnt smɔl. insay dis kכndyushכn, di pletlet kכnt kin nכmal fכ de bitwin 40,000 εn 80,000 pan wan maykrolit bכdi. Sɔntɛnde, i kin ivin bi nɔmal tin. mεmba se nכmal wan wi kin kכnsidr ``lכw'' if di pletlet kכnt sכmtεm sכmtεm 150,000 pan wan maykrolit bכdi.
• Peripheral Blood Smear (PBS): Dis PBS tɛst kin chɛk yu pletlɛt kɔnt. i de chεk bak fכ di prεsεns fכ dεn strכkchכ dεm we lεk rod we dεn kכl Döhle bכdi dεm, we wi bin tכk bכt fכs, insay yu lukosayt dεm.
• Jεnεtik tεst dεm: Dis tεst kin kכnfכm if yu gεt mכtεshכn na yu `MYH9` jin.

Apat frɔm dat, yu dɔktɔ go luk fɔ ɔda sayn dɛn we de sho se di pletlɛt dɛn nɔ de bɔku, lɛk we di blɔd de bɔku.

Aw dɛn kin trit May-Hegglin Anomaly?

Infakt, bɔrku pipul dɛm wae gɛt May-Hegglin Anomaly nɔr kin gɛt sɔm kayn sik wae de kam wae dɛn nid tritmɛnt. Dat na rial rilif, nɔto so? Bɔt if yu gɛt fɔ du ɔpreshɔn, yu dɔktɔ go nid fɔ tek tɛm fɔ mek yu nɔ blɔd pasmak. Fɔ ɛgzampul, dɛn kin gi wan mɛrɛsin we dɛn kɔl dɛsmɔprɛsin insay di bɛlɛ bifo dɛn du di ɔpreshɔn fɔ mek dɛn nɔ gɛt bɔku blɔd, ɔ dɛn kin gi pɔsin pletlɛt transfyushɔn.

If yu blɔd pasmak, lɛk we yu gɛt aksidɛnt, yu go nid fɔ gi yu pletlɛt fɔ mek yu pletlɛt dɛn go bak.

If yu gɛt bɛlɛ, yu go mɔs nid ɔda monitarin. כl di uman dεm we gεt May-Hegglin Anomaly kin bכn hεlty pikin dεm we nכ gεt εni kכmplikεshכn. Bɔt ɛni kɔndishɔn we de mek di blɔd kɔmɔt na di bɔdi kin gɛt prɔblɛm we uman gɛt bɛlɛ. So, yu dɔktɔ we de mɛn uman dɛn we de bɔn pikin ɛn we de mɛn uman dɛn go advays yu bɔt wetin fɔ du fɔ protɛkt yusɛf ɛn di pikin we yu nɔ bɔn yet. I rili impɔtant fɔ fala dɛn instrɔkshɔn dɛn de.

Wetin fɔ ɛkspɛkt we yu de liv wit di ‘May-Hegglin Anomaly’?

Di May-Hegglin Anomaly na wan sik wae de kam wae yu de liv yu layf. Na tru.Bɔt, fɔtunate wan, fɔ bɔrku pipul dɛm, dis nɔr kin kɔz big prɔblɛm na dɛn ɛvride layf. Bɔrku pipul dɛm wae gɛt dis sik nɔr kin gɛt ɛni sayn, ɔr kin gɛt bɔrku sayn dɛm nɔmɔ. If yu pletlɛt nɔ bɔku ɛn yu de gɛt prɔblɛm, yu dɔktɔ go advays yu bɔt aw fɔ kɔntrol blɔd if yu gɛt injury. So natin nɔ de fɔ wɔri bɔt.

Yu tink se dɛn kin ebul fɔ stɔp di ‘May-Hegglin Anomaly’?

Infakt, natin nɔ de we yu go du fɔ mek yu nɔ gɛt May-Hegglin Anomaly. Dis na wan sik we pɔsin kin gɛt we i kam pan jɛnɛtiks. Bɔt if yu de plan fɔ bɔn pikin, mɔ if yu ɔ yu patna gɛt dis sik, i go fayn fɔ mek yu tɔk to pɔsin we de advays yu bɔt yu jɛnɛtiks. If yu ɔ yu patna gɛt May-Hegglin Anomaly, yu pikin gɛt 50% chans fɔ gɛt di sik.

Wan pɔsin we de advays yu bɔt yu jɛnɛtiks kin asɛs ɛni prɔblɛm we yu go gɛt ɛn advays yu bɔt di tin dɛn we yu go ebul fɔ du. Dat kin rili ɛp wi.

Aw a kin kia fɔ misɛf? (Fɔ kia fɔ yusɛf) .

If yu kam fɔ no se yu gɛt May-Hegglin Anomaly, wan pan de bɛst tin wae yu kin du na fɔ tɔk to yu dɔktɔ bɔt aw fɔ kɔntrol di sik. I impɔtant fɔ no bɔt dɛn tin ya:

• Tek tɛm wit mɛrɛsin: Sɔm mɛrɛsin kin afɛkt di we aw yu pletlɛt dɛn de wok. So, fɛn ɔl di mɛrɛsin dɛn we de ambɔg yu, aw fɔ avɔyd dɛn, ɔ aw fɔ tek dɛn we sef. Nɔ yuz ɛni mɛrɛsin we yu nɔ aks yu dɔktɔ.
• Mek yu gɛt gud ɔral hajɛns: If yu tek tɛm kia fɔ yu mɔt fayn fayn wan, dat kin ɛp fɔ mek yu nɔ gɛt blɔd na yu gɔm. I fayn bak fɔ go to dɛntist ɔltɛm.
• Tek tɛm wit tin dɛn we kin mek pɔsin wund: Tek tɛm bad bad wan we yu de ple spɔt we kin mek pɔsin wund (fɔ ɛgzampul, kɔntakt spɔt). Yu go ivin nid fɔ avɔyd dɛn. Tɔk to yu dɔktɔ bɔt dis bak.
• Yu fɔ no di prɔblɛm dɛn we kin apin we yu gɛt bɛlɛ: Fɔ avɔyd prɔblɛm we yu gɛt bɛlɛ bikɔs ɔf ‘May-Hegglin Anomaly’, wach yu wɛlbɔdi ɛn wok klos wit yu ɔbstetrishan ɛn gaynekɔlɔjis.

Wetin a fɔ aks mi dɔktɔ?

Na sɔm kwɛstyɔn dɛn fɔ aks yu dɔktɔ if yu kam fɔ no se yu gɛt May-Hegglin Anomaly:

• "Dɔkta, aw siriɔs mi pletlɛt dɛfisiɛns (thrombocytopenia)?"
• "Ustɛm a fɔ wɔri se mi pletlɛt kɔnt de drɔp?"
• "Us simptom a fɔ spɛshal luk fɔ?"
• "Us chenj a nid fɔ mek na mi ɛvride layf fɔ manej dis kɔndishɔn?"
• "I fayn fɔ mek mi ɛn mi patna gɛt jenɛtik kɔyl?"

Nɔ ɛva fred fɔ aks kwɛstyɔn dɛn lɛk dis. I rili impɔtant fɔ mek yu klia ɛni dawt we yu gɛt.

Ɔda sik dɛn de we gɛt fɔ du wit di `MYH9` jin?

Yes, May-Hegglin Anomaly na wan grup fɔ sik dɛn we gɛt fɔ du wit di MYH9 jin. כl dεn sik ya de kכz fכ wan mכtεshכn na di MYH9 jin. Risach dɔn sho se, apat frɔm May-Hegglin Anomaly, tri ɔda kɔndishɔn dɛn we de mek di pletlɛt dɛn nɔ nmal ɛn di pletlet dɛn we nɔ de bɔku kin apin bak bikɔs ɔf di chenj dɛn we de apin na di MYH9 jin. Di ɔda tri tin dɛn na:

• Sindrom we gɛt di sik we dɛn kɔl Epstein
• Fechtner sindrom we gɛt di sik
• Sebastian sindrom we gɛt di sik

Bikɔs ɔl dɛn sik ya gɛt fɔ du wit dɛnsɛf, ɛn bikɔs dɛn ɔl gɛt di sem kɔz, i pɔsibul se as tɛm de go dɛn difrɛn nem ya go dɔnawe, ɛn dɛn go kɔl dɛn ɔl togɛda "MYH9-related disorders."

So, wetin na di impɔtant tin we wi fɔ mɛmba frɔm dis stori? (Mɛsej we dɛn kin tek go na os)

May-Hegglin Anomaly na wan kכndyushכn we de involv abnכmal big pletlεt dεm εn lכw pletlet kכnt. Bɔt, i nɔ min se yu go gɛt big big prɔblɛm dɛn. Wit dis kכndyushכn, bכku tin de dipכnt pan aw yu pletlet kכnt lכw. Bɔrku pipul dɛm wae gɛt dis sik gɛt inof pletlɛt fɔ mek dɛn nɔr gɛt siriɔs blɔd. Ɔda pipul dɛn kin de pan denja fɔ mek dɛn blɔd pasmak.

So, di tin we impɔtant pas ɔl na fɔ tɔk to yu dɔktɔ, ɔndastand gud gud wan wetin yu nid fɔ tek tɛm wit fɔ mek yu nɔ gɛt bɔku blɔd, ɛn du wetin yu want. Di tin we impɔtant pas ɔl na fɔ lɛ wi nɔ fred, fɔ mek dɛn no bɔt wi, ɛn fɔ fala di advays we dɔktɔ gi wi. Gud wɛlbɔdi fɔ yu!

` May-Hegglin Anomaly, pletlet, trombocytopenia, MYH9 jin, blɔd, jɛnɛtik sik, blɔd sik