Yu go lɛk fɔ no bɔt di injɛkshɔn fɔ mɛtɔtreks? Mek wi tok!

Yu dɔktɔ dɔn gi yu wan mɛrɛsin we dɛn kɔl Methotrexate ? Ɔ yu dɔn gi dis mɛrɛsin to pɔsin we yu sabi? Sɔntɛm di nem kin tan lɛk se yu sabi am smɔl. Dis na mɛrɛsin we dɛn kin rili gi fɔ bɔku difrɛn sik dɛn , ɛn i nid fɔ tek tɛm. So, yu tink se wi go tɔk bɔt am ditayli ɛn rili simpul wan tide?

Us kayn mɛrɛsin dis? (Wetin na Mɛtɔtreksɛt?)

Fɔ tɔk am simpul wan, Methotrexate na wan mɛrɛsin we de ridyus di inflamɛns na di bɔdi mɔ. Yu mɛmba se sɔmtɛm we yu jɔyn dɛn kin at ɛn swel, na bikɔs ɔf inflamɛns insay di bɔdi. Na dat mek dɛn kin yuse am bɔku tɛm fɔ di kɔndishɔn dɛn we kin kam wit inflamɛns.

Fɔ ɛgzampul:

• Atraytis : Dis na inflamɛns na di jɔyn dɛn . Dis kin mek di jɔyn dɛn pen, swel, ɛn sɔntɛnde i kin pwɛl fɔ lɔng tɛm. Methotrexate kin ridyus dis inflamɛns, ridyus pen , ɛn ɛp fɔ mek di jɔyn dɛn nɔ pwɛl mɔ.
• Psoriasis: Dis na sik na di skin. Sɔm pipul dɛn gɛt rɛd, flaky skin, nɔto so? Na dat mek dɛn de gi dis mɛrɛsin.

Nɔto dis nɔmɔ, bɔt dɛn kin yuz Methotrexate bak fɔ mɛn sɔm kayn kansa . Wetin dis mɛrɛsin de du na fɔ slo di kansa sɛl dɛn we de gro.

So yu go dɔn ɔndastand se dis nɔto mɛrɛsin we dɛn kin gi fɔ wan sik nɔmɔ. Na yu dɔktɔ go disayd if yu nid dis mɛrɛsin ɔ nɔ nid am, ɛn fɔ us kɔndishɔn dɛn go gi am. So if yu gɛt ɛni ɔda kwɛstyɔn, nɔ fred fɔ aks yu dɔktɔ ɔ fama.

Wetin a fɔ tɛl di dɔktɔ bifo a tek dis mɛrɛsin?

Bifo yu gi yu Methotrexate, yu dɔktɔ go aks yu sɔm kwɛstyɔn dɛn. Sɔm tin dɛn de bak we yu fɔ rili tɛl dɛn . Dis mɛrɛsin nɔto fɔ ɔlman. Yu nid fɔ rili tek tɛm we yu de gi am to pipul dɛn we gɛt sɔm kayn sik.

If yu gɛt ɛni wan pan dɛn tin ya, mek shɔ se yu tɛl yu dɔktɔ:

• If wata de na di bɛlɛ eria ɔ wata de na di lכng.
• If yu na pɔsin we de drink ɔltɛm, dis rili impɔtant.
• If infekshɔn de na di bɔdi, ɔ if wikɛd tin dɛn de na di imyun sistɛm.
• If yu gɛt sik na yu kidni.
• If yu gɛt liva sik.
• If yu gɛt smɔl blɔd kɔnt, lɛk wayt blɔd sɛl, pletlɛt, ɔ rɛd blɔd sɛl, dɔktɔ dɛn kin kɔl dis bak ``lɔ blɔd kɔnt.''
• If yu gɛt lɔng sik.
• If yu jɔs dɔn gɛt redyushɔn tɛrapi, ɔ yu dɔn arenj fɔ gɛt am tumara bambay.
• If yu jɔs dɔn gɛt wan vaysin, ɔ yu de plan fɔ gɛt wan tumara bambay, yu fɔ tek tɛm mɔ wit sɔm layf vayrɔs vaysin dɛn.
• If yu gɛt ɔlsa na yu bɛlɛ.
• If yu gɛt inflammatory bowel condition lɛk ɔlsa kɔlayt.
• If yu bin dɔn gɛt alɛji fɔ mɛtɔtreksɛt, ɔda mɛrɛsin dɛn, it dɛn, day, ɔ tin dɛn we dɛn kin yuz fɔ mek tin nɔ pwɛl.
• If yu de tray fɔ gɛt bɛlɛ ɔ yu gɛt bɛlɛ naw, dis na impɔtant pɔynt.
• If yu na mama we de gi pikin in bɛlɛ.

I rili impɔtant fɔ yu yon sef fɔ tɛl yu dɔktɔ bɔt dɛn tin ya we yu nɔ go ayd. Dɔn di dɔktɔ kin pik di tritmɛnt we go fayn fɔ yu.

Aw yu kin yuz dis mɛrɛsin?

Methotrexate nɔto mɛrɛsin we dɛn kin tek as pil. Dɛn kin gi am as injɛkshɔn . Dat min se, tru wan nidul.

Bɔku we dɛn de fɔ du dis:

• Infushɔn insay vein: Sɔntɛnde dɛn kin gi am as salin sɔlvushɔn, miks wit am, dɔn dɛn kin put am smɔl smɔl insay vein.
• Injɛkshɔn insay wan mɔsul.
• Injεkshכn insay di spεnal fכluid: Dis na sכmtin we dεn kin du pan sכm spεshal kes dεm.

Bɔku tɛm dɛn kin gi dis mɛrɛsin na ɔspitul ɔ klinik , bikɔs sɔntɛnde dɛn kin nid dɔktɔ fɔ kia fɔ am we dɛn de gi am.

Bɔt, insay rare cases , yu dɔktɔ kin tɛl yu fɔ tek dis mɛrɛsin na os. If na so i bi, dɛn go tɛl yu aw fɔ du am. I rili impɔtant fɔ tek di mɛrɛsin jɔs lɛk aw dɛn tɛl yu fɔ tek am, di rayt tɛm . Nɔ tek am pas wetin di dɔktɔ tɛl yu fɔ tek, ɔ tek am bɔku tɛm.

Speshal mɛsej fɔ mɛmba:

If dɛn gi yu dis mɛrɛsin fɔ at at sik ɔ psoriasis, dɛn kin tek am wan tɛm insay di wik. Nɔ tek am ɛvride. Dis rili impɔtant! Fɔ fala yu dɔktɔ in instrɔkshɔn dɛn di rayt we.

We yu de yuz injɛkshɔn, i rili impɔtant fɔ trowe di nidul ɛn sirinj dɛn we yu dɔn yuz fayn fayn wan . Nɔ trowe dɛn na dɔti. Bifo dat, put dɛn insay spɛshal kɔntena we gɛt shap tin dɛn . If yu nɔ gɛt wan, aks yu fama ɔ dɔktɔ fɔ wan. Dis kin sef fɔ di envayrɔmɛnt ɛn fɔ ɔda pipul dɛn.

Yu tink se dɛn kin gi dis mɛrɛsin to smɔl pikin dɛn?

Yɛs, sɔntɛnde dɔktɔ dɛn kin gi dis mɛrɛsin to pikin dɛn we ol 2 ia fɔ sɔm mɛrɛsin dɛn. Bɔt sɔm tin dɛn de we wi fɔ rili tek tɛm wit we wi de gi am. If yu de gi pikin dis mɛrɛsin, di dɔktɔ go ɛksplen am to yu.

Wetin kin apin if yu tek bɔku mɛrɛsin? (Ovadosage) .

If yu tink se yu dɔn tek dis mɛrɛsin tumɔs, kɔl pɔyzin kɔntrol sɛnta ɔ imejensi rum wantɛm wantɛm. Nɔ delay.

Wan ɔda tin: Dis mɛrɛsin na fɔ yu nɔmɔ. Nɔ gi dis mɛrɛsin to ɔda pɔsin , ilɛksɛf dɛn gɛt di sem sayn lɛk yu. Di rayt mɛrɛsin ɛn di doz fɔ ɛnibɔdi difrɛn.

Wetin fɔ du if yu mis wan doz fɔ mɛrɛsin?

I rili impɔtant fɔ mek yu nɔ mis di doz we dɛn gi yu fɔ dis mɛrɛsin. If yu nɔ ebul fɔ kip yu apɔntinmɛnt ɔ yu mis wan doz, kɔl yu dɔktɔ ɔ in tim wantɛm wantɛm.

If yu de tek yu mɛrɛsin na os ɛn yu mis wan doz, tɔk to yu dɔktɔ bɔt am. Nɔ ɛva tek dɛbul doz ɔ ɛkstra doz fɔ mek di doz we yu mis.

Us ɔda mɛrɛsin dɛn kin miks wit dis mɛrɛsin? (Intarakshɔn dɛn)

Dis na pat we rili impɔtant. Methotrexate na wan mɛrɛsin wae kin intarakt wit bɔrku ɔda mɛrɛsin dɛm. Dis min se ɔda mɛrɛsin we yu de tek kin chenj aw Methotrexate de wok, ɔ Methotrexate kin chenj aw ɔda mɛrɛsin de wok. Sɔntɛnde, di sayd ɛfɛkt dɛn kin bɔku.

Nɔ ɛva tek mɛtɔtreksɛt wit dɛn mɛrɛsin ya:

• Acitretin ( na mɛrɛsin bak fɔ wan sik we de mek pɔsin in skin) .

Dɔn bak, dɛn mɛrɛsin ya kin miks wit Methotrexate. So mek shɔ se yu tɛl yu dɔktɔ if yu de tek ɛni wan pan dɛn tin ya:

• Aspirin ɔ drɔgs we tan lɛk aspirin, drɔgs we gɛt salicylates.
• Azatiɔprin we dɛn kɔl
• Sɔm antibayɔtik dɛndi kayn dεm: fכ egzampl `(kloramfεnikכl)`, `(pεnisilin)`, `(tεtrasayklin)`.
• Sɔm mɛrɛsin dɛm we de mek blɔd nɔ klɔt ɔ trit: Fɔ ɛgzampul `(warfarin)`, `(apixaban)`, `(dabigatran)`, `(rivaroxaban)`.
• Sɔm mɛrɛsin fɔ mek yu bɛlɛ at pwɛl: Fɔ ɛgzampul `(esomeprazole)`, `(omeprazole)`, `(pantoprazole)`.
• Sayklɔspɔrin we dɛn kɔl
• Dapsone we de na di wɔl
• Diuretics ( mɛrɛsin dɛn we de pul wata na di bɔdi) .
• Fɔlik asid. (Bɔt sɔntɛnde, di dɔktɔ kin gi smɔl doz fɔlik asid wit mɛtɔtreksɛt fɔ ridyus di sayd ɛfɛkt dɛn. Dis na di dɔktɔ in yon sɛns.)
• Gold (dɛn kin gi am fɔ sɔm at at sik dɛn) .
• Haydroksiklɔrokin we dɛn kɔl
• Layf vayrɔs vaysin dɛn
• Mɛrɛsin fɔ infɛkshɔn: Ɛgzampul dɛn na `(acyclovir)`, `(adefovir)`, `(amphotericin B)`, `(bacitracin)`, `(cidofovir)`, `(foscarnet)`, `(ganciclovir)`, `(gentamicin)`, `(pentamidine)`, `(vancomycin)`.
• Mɛkaptopurin we dɛn kɔl
• NSAID (N.S.A.I.D.) na mɛrɛsin dɛn we de mek pɔsin fil pen ɛn we de mek pɔsin nɔ fil bad: Fɔ ɛgzampul, ibuprofen ɔ naproxen.
• Pamidronate we dɛn kɔl Pamidronate
• Pemetrexed we dɛn kɔl Pemetrexed
• Penisilamin we dɛn kɔl
• Fɛnilbutazɔn we dɛn kɔl
• Fɛnitoin we dɛn kɔl
• Probenecid we dɛn kɔl Probenecid
• Pirimɛtamin
• rεtinoyd dεm (lεk vaytam in A): εgzampl dεm na isotretinoin εn tretinoin.
• Stɛroyd mɛrɛsin dɛn: Fɔ ɛgzampul, prɛdnison ɔ kɔtizɔn.
• Salfonamid dεm: εgzampl dεm na `(sulfasalazine)` εn `(trimethoprim/sulfamethoxazole)`.
• Tiofilin we dɛn kɔl
• Zoledronic asid we de na di wɔl

Sɔntɛm dis list nɔ go kɔmplit. So, tɛl yu dɔktɔ bɔt ɔl di mɛrɛsin dɛn we yu de tek (we dɔktɔ gi yu, we yu nɔ de bay na kɔt), tradishɔnal mɛrɛsin dɛn, vaytamɛn dɛn (di it we yu de it), ɛn if yu de smok, drink rɔm, ɔ yuz ɔda mɛrɛsin dɛn. Sɔm tin kin miks wit yu mɛrɛsin.

Wetin na de tin wae yu fɔ tek tɛm wit we yu de tek dis mɛrɛsin?

We yu tek methotrexate, yu kin fil smɔl smɔl ɛn yu kin sik pas aw yu kin fil.Yu kin fil am. Dis nɔto tin we nɔ kɔmɔn. Dis na bikɔs dis mɛrɛsin, mɔ we dɛn gi am to pipul dɛn we gɛt kansa, i nɔ kin afɛkt di kansa sɛl dɛn nɔmɔ bɔt i kin afɛkt di sɛl dɛn we gɛt wɛlbɔdi bak. So, if yu gɛt ɛni sayd ɛfɛkt, tɛl yu dɔktɔ. Bɔt kɔntinyu fɔ tek di tritmɛnt we dɛn gi yu te yu dɔktɔ tɛl yu fɔ stɔp, ilɛksɛf yu nɔ fil fayn.

Yu dɔktɔ go wach yu sik gud gud wan we yu de tek dis mɛrɛsin. I kin du ɛni tɛst bak we i nid.

• Nɔ drink rɔm. Dis na impɔtant tin bikɔs rɔm kin mek dis mɛrɛsin gɛt mɔ pawa pan di liva.
• Dis mɛrɛsin kin mek pɔsin gɛt siriɔs sayd ɛfɛkt . Fɔ ridyus dis risk, yu dɔktɔ kin gi yu ɔda mɛrɛsin bifo yu bigin fɔ tek mɛtɔtreks. Fɔ fala yu dɔktɔ in instrɔkshɔn dɛn di rayt we.
• Dis mɛrɛsin kin mek yu skin fil bad fɔ di san . So, nɔ fɔ de na di san as yu ebul. If yu fɔ go na do na di san, wɛr klos we de kɔba yu skin, wɛr sanglas, ɛn yuz sanskrin. Nɔ yuz san lamp ɔ tanning bed/booth.
• Yu kin fil lɛk se yu de slip ɔ yu kin gɛt diziz . So, te yu no aw dis mɛrɛsin de afɛkt yu, nɔ drayv, ɔpreshɔn mashin, ɔ du ɛnitin we nid fɔ pe atɛnshɔn . Nɔ tinap ɔ sidɔm kwik kwik wan, mɔ if yu dɔn ol. Dis kin mek yu nɔ gɛt diziz ɛn fɔdɔm.
• Yu go nid fɔ mek dɛn du blɔd wok we yu de tek dis mɛrɛsin. Du di tɛst dɛn lɛk aw yu dɔktɔ tɛl yu.
• If yu gɛt sɔm sayn dɛn lɛk fiva, kol, trot we de at, ɔ kol , kɔl yu dɔktɔ fɔ advays. Nɔ tek mɛrɛsin fɔ yusɛf. Dis mɛrɛsin kin mek yu bɔdi nɔ ebul fɔ fɛt di sik dɛn we yu gɛt . So tray fɔ de fa frɔm pipul dɛn we sik as yu ebul.
• Dis mɛrɛsin kin mek yu gɛt mɔ blɔd ɔ brus. If yu notis ɛni blɔd we nɔ kɔmɔn (e.g. blɔd we de kɔmɔt na yu nos, blɔd na yu gɔm, blak tarry stɔl), tɛl yu dɔktɔ wantɛm wantɛm.
• Tek tɛm bad bad wan we yu de brus, yuz flos, ɔ yuz tutpik. Dis kin izi fɔ mek yu gɛt infɛkshɔn ɔ blɔd. If yu de gɛt ɛni tritmɛnt fɔ yu tit, tɛl yu dɛntist se yu de tek dis mɛrɛsin.
• If yu gɛt bad bad dayarɛa, yu nɔs, yu de vɔmit, ɔ yu de swet pasmak , tɔk to yu dɔktɔ. If yu lɔs bɔku wata na yu bɔdi, i kin denja fɔ mek yu tek dis mɛrɛsin.
• Tɔk to yu dɔktɔ bɔt di risk fɔ gɛt kansa.Dɛn se if yu tek dis mɛrɛsin, yu go gɛt sɔm kayn kansa kin go ɔp smɔl. Bifo yu panik, aks yu dɔktɔ fɔ advays.

Tek spɛshal kia we yu gɛt bɛlɛ, we yu de gi pikin in bɛlɛ, ɛn we yu de bɔn pikin.

Dis na pɔynt we rili impɔtant.

• Nɔ gɛt bɛlɛ we yu de tek dis mɛrɛsin ɛn fɔ 6 mɔnt afta yu dɔn stɔp di mɛrɛsin. If yu de plan fɔ gɛt bɛlɛ ɔ yu tink se yu go gɛt bɛlɛ, tɛl yu dɔktɔ wantɛm wantɛm.
• If man de tek dis mɛrɛsin, i nɔ fɔ papa pikin we i de tek di mɛrɛsin ɛn fɔ 3 mɔnt afta i dɔn stɔp di mɛrɛsin.
• I kin mek di pikin we nɔ bɔn yet gɛt siriɔs prɔblɛm . Aks yu dɔktɔ fɔ no mɔ bɔt dis.
• Nɔ gi yu pikin in bɛlɛ we yu de tek dis mɛrɛsin ɛn fɔ wan wik afta yu dɔn stɔp di mɛrɛsin.
• Dis mɛrɛsin kin afɛkt yu ebul fɔ gɛt bɛlɛ ɔ fɔ bɔn pikin . If yu gɛt ɛni kwɛstyɔn bɔt aw yu go ebul fɔ bɔn pikin, tɔk to yu dɔktɔ.

Pan ɔl we dɛn instrɔkshɔn ya lɔng smɔl, dɛn ɔl rili impɔtant fɔ mek yu sef. If ɛnitin de we yu nɔ ɔndastand, aks yu dɔktɔ bak.

Wetin na di sayd ɛfɛkt dɛm we dis mɛrɛsin kin gɛt?

Lɛk ɛni mɛrɛsin, mɛtɔtreksɛt kin mek sɔm pipul dɛn gɛt sayd ɛfɛkt. Nɔto ɔlman kin gɛt dɛn, sɔm pipul dɛn kin gɛt dɛn. Sɔm sayd ɛfɛkt dɛn kin siriɔs, ɛn yu fɔ tɛl yu dɔktɔ wantɛm wantɛm if dɛn apin. Sɔm nɔ kin siriɔs, bɔt if dɛn kɔntinyu fɔ de ɔ de mɔna yu, yu fɔ tɛl yu dɔktɔ.

Di sayd ɛfɛkt dɛm we yu fɔ ripɔt to yu dɔktɔ wantɛm wantɛm:

• Alɛji riakshɔn: skin rɔsh, it, ayv (hayv), swel na yu fes, lip, tɔng, ɔ trot.
• Blɔd klɔt: yu leg de pen, yu de swel, ɔ yu de wam, i nɔ izi fɔ blo, yu chɛst de pen.
• Dray kɔf, i nɔ kin izi fɔ blo, ɔ i kin shɔt fɔ blo.
• Infεkshכn: Fiva, kol, kכf, trot we de at, wund dεm we nכ de hεl, pen כ tranga fכ pis, jεnarכl diskכmfכt, εn fil bכku.
• Kidni injuri: Di ​​urine we de kɔmɔt na di bɔdi nɔ de bɔku, di anklɛ, an, ɔ fut de swel.
• Liva injuri: Pen na di ɔp rayt say na di bɛlɛ, yu nɔ de want fɔ it, yu nɔ de fil fayn, yu de stɔl we gɛt layt kɔlɔ, yu urine we gɛt dak yɔlɔ ɔ brawn, yu skin ɔ yu yay de yɔlɔ, yu taya ɔ yu wik we yu nɔ kɔmɔn.
• Low red blood cell count (Anemia): I nɔ kin taya ɔ wikɛd, diziz, ed we de at, we i nɔ de blo fayn.
• di skin kin rεd, blista, kכl, כ kכl di skin kin apin bak insay di mכt.
• Di sik dɛn we kin mek pɔsin sik.
• Brus ɔ blɔd we nɔ kɔmɔn.

Sayd ɛfɛkt dɛm wae nɔr kin nid dɔktɔ advays, bɔt yu fɔ ripɔt to yu dɔktɔ if dɛn kɔntinyu ɔr de mɔna yu:

• Rɔnbɛlɛ
• Diziz we pɔsin kin gɛt
• I kin lɔs (Dis nɔ kin apin to ɔlman, na sɔm pipul dɛn nɔmɔ. I kin gro bak afta dɛn dɔn stɔp di mɛrɛsin.)
• Vɔmit
• Sɔl na di mɔt ɔ trot wit pen, rɛd, ɔ swel.
• Fɔ vɔmit

Dis list nɔ kin gɛt ɔl di sayd ɛfɛkt dɛn. If yu notis ɛnitin we nɔ kɔmɔn apat frɔm dɛn tin ya, aks yu dɔktɔ bɔt am. Yu kin ripɔt bak di sayd ɛfɛkt dɛn to di FDA, bɔt na Sri Lanka, i bɛtɛ fɔ tɛl yu dɔktɔ dairekt wan.

Usay yu kin kip dis mɛrɛsin?

Bikɔs dɛn kin gi dis mɛrɛsin na ɔspitul ɔ klinik , yu nɔ nid fɔ kip am na os. So yu nɔ nid fɔ wɔri bɔt am. If dɛn nɔ kin gi yu am na os, yu dɔktɔ ɔ fama go tɛl yu aw fɔ kip am (fɔ ɛgzampul, if yu fɔ kip am na frij ɔ usay di san nɔ de).

Fɔ dɔn, di impɔtant tin dɛn we yu fɔ mɛmba (Take-Home Message) .

So, yu go dɔn ɔndastand naw se Methotrexate na wan mɛrɛsin we rili yusful, bɔt na wan we nid sɔm tɛm fɔ tek tɛm.

• Fɔ fala yu dɔktɔ in instrɔkshɔn dɛn di rayt we. Mek shɔ se yu fala di doz, di tɛm fɔ di de, ɛn di de insay di wik (especially wan tɛm insay di wik fɔ at at sik ɛn soriasis).
• Tɛl yu dɔktɔ bɔt ɔl di ɔda mɛrɛsin dɛn we yu de tek, ɛni ɔda sik we yu gɛt, ɛn ɛni alɛji we yu gɛt .
• If yu gɛt bɛlɛ, yu de tray fɔ gɛt bɛlɛ, ɔ yu de gi pikin in bɛlɛ, mek shɔ se yu tɛl yu dɔktɔ. Dis rili impɔtant.
• Yu fɔ no bɔt di bad tin dɛn we kin apin to yu. If yu gɛt ɛni siriɔs sayd ɛfɛkt, tɛl yu dɔktɔ wantɛm wantɛm.
• Nɔ drink rɔm kpatakpata.
• Nɔ skip di blɔd tɛst we dɛn dɔn sɛtul ɛn di apɔntinmɛnt fɔ dɔktɔ.
• If yu gɛt ɛni kwɛstyɔn ɔ dawt, nɔ fred fɔ aks di dɔktɔ. Yu gɛt rayt fɔ no ɔltin klia wan.

Mɛmba se dis mɛrɛsin na fɔ ɛp yu fɔ kɔntrol yu sik. So, lɛ wi wok wit di dɔktɔ ɛn fala dis tritmɛnt ɛksaktɔli. Wi de wish yu fɔ wɛl kwik kwik wan!

` Methotrexate, at at, psoriasis, kansa, mɛrɛsin, sayd ɛfɛkt, mɛrɛsin, jɔyn pen