Yu no bɔt dis denja fɔŋ infɛkshɔn? (Mucormycosis) Lɛ wi tɔk!

Yu don eva yehri boht dis 'blak fungus'? Sɔntɛm yu yɛri am na nyuspepa ɔ na TV nyuz. Na tru tru wan sik we de mek pɔsin fred ɛn we kin rili siriɔs. Tide, lɛ wi tɔk bɔt dis fεn infεkshכn, we dεn kכl Mucormycosis fכ mεdikal, insay simpul tεm dεm.

Wetin na Mucormycosis?

Fɔ tɔk am simpul wan, Mucormycosis na wan rili siriɔs fɛns infɛkshɔn . Na wan grup we dɛn kɔl mucormycetes kin mek am. Dɛn fɛns ya kin afɛkt bɔku difrɛn pat dɛn na wi bɔdi. Fɔ ɛgzampul, i kin afɛkt yu yay, sayn (di say dɛn we de na yu fɔɛd ɛn yu chɛst), yu bren, yu lɔng, yu bɛlɛ ɛn yu intestinal (gastrointestinal tract), ɔ yu skin.

If na so i bi, di sayn dɛm kin difrɛn difrɛn wan dipen pan us pat na yu bɔdi we di fɛns afɛkt. Sɔntɛnde dɛn kin kɔl am zygomycosis.

Naw imajin, dɛn fɛns ya we dɛn kɔl mucomycetes de liv na di envayrɔmɛnt we de rawnd wi, mɔ na grɔn, kɔmpɔst, lif dɔti we de rɔtin, ɛn wud chips. Bɔt i sɔprayz fɔ no se bɔku pan wi nɔ kin sik frɔm dɛn fɛns ya. Bɔt pipul dɛm wae gɛt shuga, sɔm kayn kansa, ɔr ɔda kayn sik wae de mek dɛn imyun sistɛm wik kin gɛt bɔrku risk fɔ gɛt mucomycosis.

Di tin we impɔtant pas ɔl na dat mucormycosis na sik we kin kil bɔku tɛm . So, if yu gɛt dɛn sik ya, yu fɔ rili go na ɔspitul ɔ go to dɔktɔ wantɛm wantɛm.

Wetin na di men kayn Mucormycosis?

difrεn men kayn mכkurmaykosis dεm de. Dɛn na:

• Di kayn we de afɛkt di nos, di yay, ɛn di bren (Rhino-orbital-cerebral ɔ Rhinocerebral mucormycosis) .
• Pulmonary mucormycosis we de mek pɔsin gɛt sik
• Mucormycosis we de kɔmɔt na di bɔdi
• di kayn we de afekt di dijestiv sistεm (Gastrointestinal mucormycosis) .
• Mucormycosis we de skata

Wetin na di sayn dɛm fɔ dis sik?

Di sayn dɛm fɔ mucormycosis de dipen pan us pat na yu bɔdi gɛt di sik. Yu kin gɛt sɔm sayn dɛn na yu nos, yu lɔng, yu dijestiv trakt, rawnd yu yay, ɔr na yu skin.

Di kayn we de afɛkt di nos, di yay, ɛn di bren (Rhino-orbital-cerebral Mucormycosis) .

Dis na di kayn mכkurmycosis we kכmכn pas כl . If na so i bi, di fכns kin fכs infεkt yu sayn dεm εn i kin spre to di כbit εn di bren. I kin kɔmɔn mɔ pan pipul dɛm wae gɛt siriɔs sik wae nɔr kin kɔntrol (fɔ ɛgzampul, A1C kin pas 8% pan ɔl wae dɛn kin trit dɛn ɔltɛm fɔ pas wan ia) ɛn pan pipul dɛm wae dɔn gɛt ɔgan transplant.

Di sayn dɛm fɔ dis kayn sik na:

• Fiva
• Ed de at
• Saynɔs pen (pen na di fɔrɛst, di chɛst) .
• Nasal kɔnjɛshɔn
• Sɔl ɔ ɔlsa na di ruf na di mɔt
• I nɔ de si fayn ɔ i nɔ de si tu tɛm
• I nɔ izi fɔ tɔn di yay ɛn smayl (dɛn kɔl dis `cranial nerve palsy`) .
• Ay dɛn we de kɔmɔt na do (proptosis) .
• Swɛlin rawnd di yay
• Blak kray wata ɔ pus frɔm di yay
• Kɔnfyushɔn ɔ ɔda chenj dɛn we kin apin to pɔsin in maynd

Pulmonary Mucormycosis we de mek pɔsin gɛt sik

dis fכn infεkshכn na di lכng dεm na di sεkכn tכp we kכmכn pas כl. I kin kɔmɔn pas ɔl na:

• Pipul dɛm wae gɛt kansa wae gɛt fɔ du wit blɔd (e.g., lukimiya, limfoma, ɔ mayloma), mɔr di wan dɛm wae gɛt sɔm wayt blɔd sɛl dɛm wae nɔr bɔku (nyutropenia) .
• Fɔ di wan dɛn we dɔn gɛt bon mɛrɔ transplant
• Fɔ di wan dɛn we dɔn gɛt sɔlid ɔgan transplant

Di sayn dɛm fɔ dis kayn:

• Fiva
• Chɛst de pen
• I nɔ izi fɔ blo (dyspnea) .
• We yu de kɔf blɔd (ɛmoptaysis) .

Mucormycosis we de kɔmɔt na di bɔdi

Dis kayn infεkshכn kin apin we fכns go insay yu skin tru wan kכt כ skrach. Imajin se yu gɛt smɔl wund ɛn sɔntin lɛk dɔti de kam pan di wund. Dis kin mek dis fכns go insay. I sɔprayz fɔ no se dis kayn tin kin apin bak pan pipul dɛn we gɛt wɛlbɔdi imyun sistɛm.

Di sayn dɛn we pɔsin kin si na di skin:

• Blista, sos, ɔ had lumps we de mek yu fil pen na yu skin
• Skin kin rɛd, di kɔlɔ kin chenj, ɔ i kin swel

Dɛn chenj ya na di skin kin wɔs as tɛm de go. Dɛn kin tɔn blak, dɛn kin skata na big say dɛn, ɛn sɔntɛnde dɛn kin go te to di mɔsul dɛn ɔ di bon dɛn.

Di kayn we de afɛkt di dijestiv sistɛm (Gastrointestinal Mucormycosis) .

Dis na infεkshכn na di bεlε כ di intestכn dεm. I kin apin mɔ pan pikin dɛn we dɛn bɔn bifo tɛm. Bɔt dis biɛn tɛm, i dɔn bɔku bak pan big pipul dɛn we nɔ gɛt bɛtɛ imyuniti (nyutropenia), pipul dɛn we de tek kɔtikosterɔyd mɛrɛsin fɔ lɔng tɛm, ɛn pipul dɛn we gɛt ɔda sik dɛn we de mek dɛn imyun sistɛm wik.

Sayn dɛn:

• Bɛlɛ de pen
• Nɔs ɛn vɔmit
• Blɔd we de kɔmɔt na di bɛlɛ

Diseminated Mucormycosis we dɛn kin gɛt

If na so i bi, di infεkshכn kin pas tru di bכdi to difrεn pat dεm na di bכdi. I kin afɛkt di bren mɔ, bɔt i kin afɛkt di at, di splin, ɔ di skin bak. Dis na di kayn we we kin rili bad ɛn we kin kil pɔsin we gɛt mucormycosis. Dɛn kin si am mɔ pan:

• Pipul dɛn we gɛt kansa we gɛt fɔ du wit blɔd, mɔ di wan dɛn we gɛt nyutropenia
• Pipul dɛn we dɛn dɔn transplant bon mɛrɔ
• Pipul dɛn we dɔn gɛt sɔlid ɔgan transplant

Bikɔs dis kayn kin afɛkt bɔku pat dɛn na di bɔdi, di ɔda kayn sik dɛn we wi dɔn tɔk bɔt kin apin bak, ɛn i kin sho bak se yu gɛt ɛni ɔndalayn mɛdikal kɔndishɔn.

Wetin mek Mucormycosis kin apin?

Mucomycosis na difrεn fכn dεm de kכz am. Di wan dɛn we kin bɔku pas ɔl na Rhizopus oryzae ɛn Rhizopus delemar. . Dɛn kin si dɛn bak na it we dɛn nɔ was fayn. Bɔku pan wi nɔ kin sik we wi de blo ɔ tɔch dɛn fɛns ya. Bɔt if yu gɛt sɔm kayn wɛlbɔdi prɔblɛm, yu imyun sistɛm nɔ go ebul fɔ fɛt di sik.

Aw dis kin kam to wi?

Yu kin gɛt mucormycosis bay we yu brith di spot dɛm (riprodaktiv pat dɛm na di fכns) na dεn fכn dεm ya, it sכmtin we gεt dεm, כ mek dεn tru wan brek na di skin. Dɛn spot ya so smɔl dat wi nɔ kin si dɛn ɔ avɔyd dɛn.

Na smɔl tɛm nɔmɔ dɛn kin gɛt am frɔm ɔspitul, tru di mɛrɛsin dɛn we gɛt dɔti, ɛn afta disasta dɛn apin. Fɔ ɛgzampul, big big briz kin mek bɔku bɔku dɔti swɛt ɛn mek di fɛns kɔmɔt na di ays.

Dis kin pas frɔm pɔsin to ɔda pɔsin?

Nɔ, di mucormycosis nɔ kin pas frɔm wan pɔsin to ɔda pɔsin. Yu kin jɔs gɛt dis fungus frɔm di envayrɔmɛnt.

Udat de pan ay risk fɔ gɛt mucormycosis?

Pipul dɛm wae gɛt shuga ɛn sɔm kayn mɛrɛsin wae de mek dɛn imyun sistɛm wik na dɛn kin gɛt dis sik pasmak. Dɔn bak, if yu gɛt bɔku ayɛn na yu bɔdi, dat kin mek dis apin. Di tin dɛn we kin mek pɔsin gɛt dis sik na:

• Dayabitis, mɔ wit kɔndishɔn lɛk aypa glycemia ɛn ketoacidosis.
• Afta dɛn dɔn transplant wan sɔlid ɔgan.
• Afta dɛn dɔn gɛt ɛmatopoiɛtik stem sɛl transplant (bɔn mɛrɔ transplant).
• Nyutropenia na we di wayt bכdi sεl dεm we dεn kכl nyutrofil dεm de dכn.
• Kansa, mɔ di lukimiya, limfoma, ɔ mayloma.
• Yuz kɔtikosterɔyd mɛrɛsin fɔ lɔng tɛm.
• Fɔ injekt drɔgs we yu nɔ gɛt dɔktɔ advays.
• wan kכndyushכn we dεn kכl εmokromatosis (we de mek di ayron we de na di bכdi go כp - `ayכn כvalod`).
• Bɔn ɔ bad bad injury na di skin we de alaw dɔti ɛn jem fɔ go insay di wund.
• Fɔ bɔn pikin bifo tɛm ɔ we dɛn bɔn am smɔl.

Fɔ tɔk am simpul wan, if yu bɔdi in sik-fayt sistɛm (immune system) wik, yu go gɛt dis.

Wetin na de prɔblɛm wae kin kam wit dis sik?

Mucormycosis kin mek yu gɛt prɔblɛm dɛn we kin pwɛl yu layf ɛn we kin mek yu layf de pan denja, lɛk:

• Cavernous sinus thrombosis: Dis na bכdi we de kכlכt we de fכm na yu sayn kכva dεm. I kin kil pɔsin.
• Fasciitis we de mek pɔsin gɛt nɛkrɔtiz:dis na wan bad bad, we de spre kwik kwik wan we di baktri infεkshכn de (dεn kכl am bak "fεshכn we de it bכdi"). I kin kil pɔsin.
• Osteomyelitis: Dis na infεkshכn na yu bon dεm. Di bon dɛn kin pwɛl.

Dɛn tin ya na rili denja, na dat mek i impɔtant fɔ gɛt tritmɛnt kwik kwik wan.

Aw yu kin no dis sik kɔrɛkt wan? (Diagnosis) .

Dɔktɔ kin sɔprayz se yu gɛt mucormycosis bay di sayn dɛm wae yu gɛt ɛn ɔda mɛrɛsin wae yu gɛt. fכ kכnfכm dis, dεn go tek pikchכ (imaging) fכ di bכdi pat dεm we afekt εn egzamin yu bכdi tisu dεm fכ si fכn dεm de.

Test fɔ dis:

• Imej: Dɛn kin du ɛkstrem rayt na di chɛst, CT skan (kɔmpyuta tomografi skan), ɔ MRI (magnɛtik rɛsɔnans imej) skan.
• εndobronchial ultrasound: Dis na wan kayn brכnkoskopi. Dis min se dɛn kin yuz ɔltra saund divays we dɛn tay pan wan tin we gɛt layt fɔ tek pikchɔ dɛn we de insay di lɔng dɛn.
• Tisu biopsy: Dɔktɔ kin luk yu tisu ɔnda maykroskɔp ɔ tru lab tɛst fɔ si if mucormycosis fungi dɛn de.

Aw dɛn kin trit Mucormycosis?

Dɔktɔ dɛn kin trit mucormycosis wit antifungal mɛrɛsin. Dɛn kin nid bak fɔ du ɔpreshɔn fɔ pul di tisu we gɛt di sik ɔ we dɔn day. Di antifungal mɛrɛsin dɛm we dɛn kin yuz fɔ dis na:

• Amfɔterisin B
• Posakonazol `(Posakonazol)`
• Isavukonazɔl we dɛn kɔl Isavuconazole

Yu go nid fɔ tek dis antifungal tritmɛnt fɔ wik, sɔntɛm mɔnt.

Yu tink se dɛn go ebul fɔ mɛn dis sik kpatakpata?

Yɛs, i pɔsibul. Bɔt i nid fɔ trit am kwik kwik wan. Ivin if di tritmɛnt delay fɔ sɔm dez, di chans fɔ liv kin ridyus bad bad wan. Ivin if dɛn bigin fɔ trit am kwik kwik wan, i nɔ kin izi fɔ mɛn am.

Kwik tritmɛnt na di bɛst chans fɔ sev pɔsin in layf!

Wetin na di rit we pipul dɛn kin day bikɔs ɔf Mucormycosis?

Bikɔs i at fɔ trit ɛn bikɔs bɔku pipul dɛn we gɛt mucormycosis gɛt wikɛd imyun sistɛm, di nɔmba fɔ pipul dɛn we de day kin bɔku. di mכtalman rεt fכ כl kayn mכkurmaykosis na bכt 54%. di mכkomaykosis we de afekt כnli di sayn dεm gεt sכm lכw lכw mכtalman rεt (bכt 46%). Bɔt bɔku tɛm, di disseminated mucormycosis we dɔn skata to ɔda pat dɛn na di bɔdi kin kil pɔsin.

Dis na siriɔs tin smɔl. Bikɔs dis sik nɔr kin izi fɔ trit, ɛn bikɔs bɔrku pipul dɛm wae gɛt am nɔr kin gɛt bɛtɛ imyuniti, di rit wae de day kin bɔrku. Bɔt nɔr giv ɔp, chans de fɔ wɛl wit tritmɛnt kwik.

Ustɛm a fɔ go to dɔktɔ?

If yu gɛt ɛni wan pan dɛn tin ya, aks dɔktɔ aw fɔ mek yu nɔ gɛt fɔŋs ɛn aw fɔ no am kwik:

• If yu gɛt dayabitis ɔ kansa.
• If yu dɔn gɛt ɔgan transplant ɔ stem sɛl transplant.
• If yu gɛt mɛrɛsin ɔ yu de tek mɛrɛsin we de mek yu imyun sistɛm wik.

Ustɛm a fɔ go na Imejɛnsi Tritmɛnt Yunit (ETU) ?

Mucormycosis kin kil pɔsin if dɛn nɔ trit am kwik kwik wan. If yu gɛt sayn dɛm fɔ mucormycosis, mɔ if yu gɛt wik imyun sistɛm ɔ yu gɛt dayabitis, go na imejensi rum wantɛm wantɛm. Ɔltɛm, go to pɔsin fɔ kia fɔ yu kwik kwik wan if yu gɛt ɛni wan pan dɛn bad bad sayn ya:

• Ay fiva (we pas 103 Fahrenheit/40 Celsius).
• I nɔ kin izi fɔ yu fɔ blo.
• Fɔ kɔf blɔd.
• Bulging yay ɔ swel rawnd di yay.
• Vishɔn kin chenj, lɛk fɔ si tu tɛm.
• Kɔnfyushɔn ɔ ɔda chenj dɛn we kin apin to pɔsin in maynd.
• Kɔnvulshɔn we pɔsin kin gɛt.
• Blak mucus ɔ kray wata.
• Wund we nɔ de wɛl, we de kɔntinyu fɔ skata, ɔ tɔn blak.

If yu gɛt ɛni wan pan dɛn sayn ya, go na ɔspitul ɛn nɔ de te!

Us kwɛstyɔn dɛn a fɔ aks mi dɔktɔ?

I go fayn fɔ aks yu dɔktɔ dɛn kwɛstyɔn ya:

• A de pan ay risk fɔ gɛt fungal infɛkshɔn?
• Wetin a go du fɔ ridyus di prɔblɛm we a gɛt?
• Us sayn dɛn a fɔ luk fɔ ɛn ustɛm a fɔ go to dɔktɔ?
• Us tritmɛnt opshɔn dɛn a gɛt?
• Wetin a kin ɛkspɛkt wit dis diagnosis?

Yu tink se we dɛn de fɔ mek yu nɔ gɛt Mucormycosis? (Prɛvenshɔn) .

di fכn dεm we de mek mכkurmaykosis de כlsay na wi, so i at fכ avכyd dεm kכmplit wan. Bɔt na sɔm tin dɛn we yu kin du fɔ ridyus yu risk fɔ gɛt fungal infɛkshɔn:

• If yu gɛt wan sik we de put yu pan denja fɔ gɛt siriɔs fɛns infɛkshɔn, wok wit yu dɔktɔ fɔ mɛn am.
• If yu de pan big risk fɔ gɛt fungal infɛkshɔn, yu dɔktɔ kin gi yu antifungals fɔ ɛp fɔ mek yu nɔ sik.
• If yu wok de put yu pan denja fɔ gɛt fɛns, aks yu dɔktɔ if yu de pan denja fɔ gɛt di sik.
• Nɔ go na say dɛn we gɛt dɔti, lɛk say dɛn we dɛn de bil. If yu rili nid fɔ de na dɛn kayn say ya, wɛr ``N95`` mask (ɔ ɔda tin dɛn we de protɛkt yu) we de ɛp fɔ filta di fεn spɔr dɛn frɔm di briz we yu de blo.
• Nɔ du tin dɛn we go mek yu gɛt fɔŋs, lɛk fɔ mek gadin ɛn fɔ dig. Wear glɔv ɛn klos we de kɔba bɔku bɔku skin as yu ebul we yu de wok na do.
• Wash di kɔt ɛn skrap dɛn fayn fayn wan wit sop ɛn wata.

Yu tink se COVID-19 de mek yu gɛt mɔ sik we dɛn kɔl Mucormycosis?

Insay 2021, di mucormycosis kes dɛm bin bɔku pan pipul dɛm we gɛt COVID-19. Bɔt masta sabi pipul dɛn nɔ shɔ ustɛm di link bi. Dɛn nɔ shɔ bak if fɔ gɛt COVID-19 insɛf na inf fɔ mek di risk bɔku, bikɔs:

• Mɔs pan di kes dɛm bin ripɔt frɔm rijyɔn dɛm na di wɔl usay mucormycosis kin kɔmɔn. Insai di COVID-19 pandemic, na lɛk 1 pan ɛvri 3 pipul dɛm we gɛt mucormycosis na dɛn rijyɔn ya nɔ bin gɛt COVID-19.
• Insay di tɛm we di sik bin de, dɛn bin ripɔt bɔku kes dɛm fɔ ɔl tu di COVID-19 ɛn mucormycosis na ɔda pat dɛm na di wɔl (we mucormycosis nɔ kin bɔku), bɔt dɛn nɔ bin gɛt di fungal infɛkshɔn na di say dɛm we mucormycosis nɔ kin bɔku.
• Bɔku pipul dɛn we bin gɛt ɔl tu di mucormycosis ɛn COVID-19 nɔ bin gɛt bɛtɛ kɔntrol pan dayabitis ɔ dɛn bin de tek kɔtikosterɔyd mɛrɛsin. Dis na risk factor fɔ mucormycosis.
• Bɔku pipul dɛn we bin gɛt ɔl tu di COVID-19 ɛn mucormycosis bin gɛt di kayn we we de afɛkt di nos, yay, ɛn bren (rhino-orbital-cerebral mucormycosis) – nɔto di tipik lɔng infɛkshɔn we yu go ɛkspɛkt. Dis de sho bak se ɔda ɔndalayn kɔndishɔn, nɔto jɔs COVID-19, de kɔntribyut to dis infɛkshɔn.

So, i at fɔ tɔk wantɛm wantɛm se na Covid-19 de kɔz dis. Ɔda tin dɛn kin de we kin mek i apin.

Fɔ dɔn, tin dɛn we wi fɔ mɛmba

Mucormycosis na wan sik we nɔ kin bɔku . I kin afɛkt lɛk wan ɔ tu pipul dɛn pan wan milyɔn ɛvri ia. Bɔt if yu gɛt ɛni wɛlbɔdi prɔblɛm we de mek yu imyun sistɛm wik, yu go gɛt mɔ prɔblɛm. Pipul dɛn we gɛt dayabitis ɛn ay A1C fɔ tek tɛm mɔ.

Fɔ manej yu ɔndalayn wɛl bɔdi kɔndishɔn na di bɛst we fɔ gɛt wɛlbɔdi. Bɔt tɔk to yu dɔktɔ bɔt ɔda we dɛn fɔ mek yu nɔ gɛt di sik. I kin tɔk bɔt ɛnitin we de mɔna yu ɛn tɛl yu us sayn dɛn fɔ tek tɛm wit.

Dis nɔto sik we de ambɔg ɔlman. Bɔt if yu gɛt sik we de mek yu imyun sistɛm wik, lɛk dayabitis, tek tɛm bad bad wan. Di tin we impɔtant pas ɔl na dat if yu gɛt sɔm sayn dɛm fɔ mucormycosis, go na di imejensi rum na di ɔspitul we de nia yu wantɛm wantɛm. Na bikɔs kwik tritmɛnt kin sev pipul dɛn layf!

` mucormycosis, blak fכns, fכn infεkshכn, dayabεtis, imyuniti, sayn, lכng, skin, bren, fכns