Yu bon mɛrɔ nɔ de wok fayn? Lɛ wi tɔk bɔt maylosupreshɔn!

Yu kin fil bak se yu jɔs nɔr de fil fayn, yu de sik ɔltɛm, ɔr yu de blɔd pan ivin smɔl kɔt, ilɛksɛf yu de gɛt kansa tritmɛnt ɔr ɔda sik? Bihayn dɛn tin ya, i kin gɛt myelosuppression , we na wan sik we di bon mɛro nɔ de wok fayn . Nɔ wɔri, lɛ wi tɔk bɔt dis simpul wan.

Wetin na maylosupreshɔn? Fɔ tɔk di kɔrɛkt tin, yu tink se na we di bon mɛrɔ wik?

Fɔ tɔk am simpul wan, yɛs! Bon mכro na di sכft, sכft tisu we de insay yu bon dεm. Tink bɔt am lɛk di faktri we de mek blɔd na wi bɔdi . Dis faktri de mek bɔku bɔku rɛd blɔd sɛl dɛn, wayt blɔd sɛl dɛn, ɛn pletlɛt dɛn, we rili impɔtant fɔ mek wi kɔntinyu fɔ liv, ɛn dɛn de ad dɛn to wi blɔd. Ɛni kayn sɛl gɛt difrɛn wok fɔ wi bɔdi. di bon mכro de inkrεs כ dכn dis prodakshכn dipכnt pan wetin wi bכdi nid.

Naw, insay wan kɔndishɔn we dɛn kɔl myelosuppression , di wok we dis bon mɛro faktri de du kin ambɔg fɔ sɔm rizin. Dɔn, dɛn nɔ kin ebul fɔ mek blɔd sɛl ɛn pletlɛt dɛn fayn fayn wan. Di men rizin fɔ dis na kemotɛrapi tritmɛnt fɔ kansa. Bɔt sɔm kayn blɔd kansa ɛn sɔm vayrɔs kin mek bak di bon mɛro nɔ wok.

Wetin na di simptom dɛm fɔ myelosuppression?

Di sayn dɛn kin difrɛn frɔm wan pɔsin to ɔda pɔsin, i kin difrɛn if yu bon mɛro de mek rɛd blɔd sɛl, wayt blɔd sɛl, ɔ pletlɛt.

If di rεd bכdi sεl dεm dכn - Anemia

Rɛd blɔd sɛl dɛn kin kɛr ɔksijɛn go ɔlsay na yu bɔdi. We dɛn nɔ bɔku , anemia kin kam. Di sayn dɛm kin bi:

• Taya
• Shortness of brith / dyspnea we yu nɔ de blo fayn
• Diziz we pɔsin kin gɛt
• Fast ɔ irɛgyula at bit / aritmia
• Sεns fכ wan ringing sawnd na di yes, sכmtεm i kin kam wit "thumping" sawnd εn at bit (Pulsatile tinnitus) .
• Ed de at
• Paleness of di skin kɔlɔ
• Chɛst de pen

Nyutropenia - we di wayt bכdi sεl dεm (especially nyutrofil dεm) de dכn .

Wait blɔd sɛl dɛn de fɛt di jem dɛn we de kam insay wi bɔdi ɛn protɛkt wi frɔm infekshɔn . Wan kayn wayt blɔd sɛl na nyutrofil . we di bon mכro de prodyuz sכm nyutrofil dεm bikoz fכ di maylosuprεshכn, dεn kכl di kכ ndyushכn nyutropenia . Nyutropenia nɔr gɛt ɛni patikyula sayn, bɔt na bikɔs ɔf disInfekshɔn kin apin ɔltɛm, ɛn na da tɛm de di sayn dɛn kin sho.

• Fiva (sɔntɛnde dɛn kin kɔl am fiva nyutropenia ) .
• We pɔsin taya
• Trot we de at/infεkshכn (Trot we de at/farinjitis) .
• Di limf no dɛm we dɔn swel
• Ɔlsa na di mɔt ɔ rawnd di an
• Rɔnbɛlɛ
• Bɔn we yu de pis, fil lɛk se yu nid fɔ pis kwik, pis ɔltɛm

if di pletlεt dεm dכn dכn - Trombocytopenia

Plɛtlɛt dɛn kin ɛp fɔ kɔntrol di blɔd we de kɔmɔt . we dεn lεvεl dεm ya dכn, wan kכndyushכn we dεn kכl trombocytopenia de apin. Dis kin mek:

• Blɔd we nɔ de stɔp fɔ lɔng tɛm, ivin frɔm smɔl wund, ɔ i nɔ izi fɔ stɔp blɔd na in nos.
• Brus kin apin kwik kwik wan pas aw i kin apin.
• di apinεns fכ sכm rεd spat dεm (lεk rash) na di lכw leg dεm - dεn kכl dis petechiae .
• Rɛd, pepul, ɔ brawn spat dɛn na di skin - dɛn kɔl dis purpura .

If ɔl di kayn blɔd sɛl dɛn dɔn ridyus - Pancytopenia

Sɔntɛnde, ɔl dɛn tri blɔd sɛl ya—rɛd blɔd sɛl dɛn, wayt blɔd sɛl dɛn, ɛn pletlɛt dɛn—kin kin smɔl di sem tɛm . Dɛn kɔl dis sik pancytopenia . Lɛk nyutropenia, dis nɔto sik insɛf, bɔt i kin bi sayn fɔ wan ɔndalayn mɛdikal kɔndishɔn.

Wetin mek maylosupreshɔn kin apin? Wetin na di tin dɛn we kin mek i apin?

As wi bin dɔn tɔk, na di tin we kin mek pɔsin gɛt kemotɛrapi . Bɔt ɔda tin dɛn de bak we kin mek pɔsin gɛt dis sik.

Kimotɛrapi, imyunotɛrapi, ɛn maylosupreshɔn

Bɔku kayn kemotɛrapi mɛrɛsin kin mek dis apin. Sɔm pan di wan dɛn we bɔku pipul dɛn kin gɛt na:

• Fluorouracil we dɛn kɔl Fluorouracil
• Oksaliplatin we dɛn kɔl
• Irinotekan we dɛn kɔl
• Kapɛsitabin we dɛn kɔl

Apat frɔm dat, CAR T-sɛl tɛrapi, we na wan kayn imyunotɛrapi , kin mek di bon mɛro nɔ wok fayn bak ɛn i kin mek di blɔd sɛl ɛn pletlɛt nɔ bɔku.

Blɔd Kansa ɛn Maylosupreshɔn

Sɔm blɔd kansa kin ambɔg bak di nɔmal blɔd sɛl dɛn we dɛn kin mek. Fɔ ɛgzampul, pan kansa dɛn lɛk lukimiya, limfoma, ɛn mayloma , di kansa sɛl dɛn we nɔ nɔmal kin gro tumɔs na di bon mɛro ɛn stɔp fɔ mek blɔd sɛl ɛn pletlɛt dɛn we gɛt wɛlbɔdi.

Vayrɔs ɛn maylosupreshɔn

Sɔm vayral infɛkshɔn kin ambɔg bak di we aw di blɔd de mek na di bon mɛro. Imajin se we wan vayrɔs kam insay di bɔdi, di tin dɛn we wi bɔdi de protɛkt, dat na di wayt blɔd sɛl dɛn, de fɛt di vayrɔs. We dɛn de fɛt dis, di bon mɛro kin mek smɔl smɔl rɛd blɔd sɛl ɛn pletlɛt dɛn. Sɔm stɔdi dɛn dɔn sho se sɔm vayrɔs dɛn kin ambɔg di sɛl dɛn we de mek blɔd na di bon mɛro dairekt wan, ɛn dis kin mek di blɔd sɛl dɛn nɔ bɔku. Sɔm vayrɔs dɛm we dɛn dɔn si se gɛt fɔ du wit dis kɔndishɔn we dɛn kɔl myelosuppression na:

• Di vayrɔs we dɛn kɔl Epstein-Barr (EBV) .
• Epataytis C vayrɔs
• Parvovayrɔs B19
• Saytomɛgalovayrɔs (CMV) .
• Di vayrɔs we de mek pɔsin gɛt chukchuk (Chickenpox / varicella zoster) .
• Human immunodeficiency vayrɔs (HIV) we gɛt fɔ du wit di sik .
• Dengue fiva we pɔsin kin gɛt

Maylosuppression kin mek siriɔs prɔblɛm dɛn?

Yɛs, sɔntɛnde dis kin mek pɔsin gɛt prɔblɛm dɛn we kin mek i day . Fɔ ɛgzampul, we di rɛd blɔd sɛl dɛn go dɔŋ wantɛm wantɛm (akyu anemia) ɔ di pletlɛt dɛn we de drɔp (blɔd we dɛn nɔ ebul fɔ kɔntrol) .

Impɔtant: If yu gɛt ɛni wan pan dɛn sik ya, mɔ if yu de gɛt kansa tritmɛnt, i rili impɔtant fɔ go to dɔktɔ wantɛm wantɛm.

Aw dɔktɔ dɛn kin no kɔrɛkt wan bɔt dis sik?

Dɛn kin no dis mɔ bay we dɛn de du blɔd tɛst . Dɛn blɔd tɛst ya kin chɛk if yu bon mɛro de mek blɔd sɛl ɛn pletlɛt dɛn nɔmal wan.

Dɛn kin du blɔd tɛst lɛk dɛn wan ya:

• Kɔmplit blɔd kɔnt (CBC) .
• MCV test (Mɛn kɔpɔskul volyum / MCV tɛst) .
• RDW test (Rɛd sɛl distribyushɔn wit / RDW tɛst) .
• rεtikulכsayt kכnt
• Pɛriferal blɔd smyuɛl
• MPV tεst (Mεn pletlet vכlyum / MPV tεst) .

Wetin na di tritmɛnt dɛm fɔ myelosuppression?

Dɔktɔ dɛn kin trit dis wit dɛn we ya:

• If di tin we kin mek di maylosupreshɔn na kemotɛrapi, dɛn fɔ ridyus di doz fɔ kemotɛrapi ɔ stɔp fɔ sɔm tɛm .
• Blɔd transfyushɔn fɔ mek di rɛd blɔd sɛl ɛn pletlɛt dɛn go ɔp.
• Fɔ gi yu mɛrɛsin dɛn we de ɛp yu bon mɛrɔ fɔ mek mɔ blɔd sɛl ɛn pletlɛt dɛn.

Yu tink se dɛn go ebul fɔ mek dis tin nɔ apin?

Maylosuppression kin apin bɔrku tɛm as sayd ɛfɛkt fɔ kansa tritmɛnt. So, dɔktɔ dɛn kin de wach ɔltɛm fɔ dɛn bad bad tin ya we dɛn de du tritmɛnt fɔ kansa. Dɛn go de chɛk yu blɔd tɛst ɔltɛm ɛn chenj yu tritmɛnt plan if nid de.

Wetin a kin ɛkspɛkt if a gɛt maylosupreshɔn?

Bɔrku pipul kin gɛt dis sik bikɔs dɛn de gɛt kemotɛrapi. If na so, yu dɔktɔ go wach gud gud wan aw di kemotɛrapi de afɛkt yu bon mɛrɔ. Yu kin nid fɔ tek shɔt briŋ frɔm kansa tritmɛnt fɔ alaw yu bon mɛrɔ fɔ bil in blɔd sɛl dɛn bak.

Aw a kin kia fɔ misɛf?

Maylosuppression kin mek yu gɛt infɛkshɔn ɛn blɔd . Yu kin du dɛn tin ya fɔ ridyus dis risk:

• Gɛt vaysin fɔ protɛkt yusɛf frɔm kɔmɔn vayrɔs.
• Praktis gud abit fɔ klin , lɛk fɔ was yu an ɔltɛm ɛn fɔ de fa frɔm pipul dɛn we sik.
• Protɛkt yusɛf frɔm tin dɛn we go mek yu wund ɔ kɔt yu . Fɔ ɛgzampul, tek tɛm we yu de yuz shap wɛpɔn.

Us kwɛstyɔn dɛn a fɔ aks mi dɔktɔ?

Yu kin aks di dɔktɔ kwɛstyɔn dɛn lɛk:

• Wetin mek a gɛt dis myelosuppression kɔndishɔn?
• Aw dis sik kin afɛkt mi bɔdi?
• Us tritmɛnt opshɔn dɛn a gɛt?
• Yu tink se tritmɛnt go mɛn mi maylosupreshɔn kpatakpata?

Sɔma: Wetin fɔ mɛmba (Take-Home Message) .

Yu bon mɛro na impɔtant pat pan yu bɔdi. Rɛd blɔd sɛl dɛm we de kɛr ɔksijɛn, wayt blɔd sɛl dɛm we de fɛt infɛkshɔn, pletlɛt dɛm we de ɛp yu blɔd fɔ klɔt – dɛn ɔl mek dɛn de. Myelosuppression na we yu bon mכro de stכp fכ wok fכ sכm rizin. Di tin we kin mek pɔsin gɛt kansa pas ɔl na kemotɛrapi fɔ kansa, bɔt sɔm blɔd kansa ɛn vayrɔs dɛn kin kam bak. Nɔ wɔri. Dɔktɔ dɛn go fɛn di rizin ɛn trit am di rayt we. Di tin we impɔtant pas ɔl na fɔ go to dɔktɔ if yu gɛt ɛnitin we nɔ kɔmɔn ɛn fala dɛn advays gud gud wan. Nɔto yu wan de, ɛn dɔktɔ dɛn de we go ɛp yu fɔ du dis waka.

` Maylosuppreshכn, Bon Mכro Suprεshכn, Bon Mכro, Rεd Blכd Sεl dεm, Wait Blכd Sεl dεm, Pletεl dεm, Kεmothεrapi, Kεnsar, Anemia, Nyutropenia, Thrombocytopenia, Infεkshכn dεm