Lɛ wi lan bɔt di Natalizumab vaysin. Dɛn dɔn gi yu dis mɛrɛsin bak?

We dɔktɔ tɛl yu ɔ pɔsin we yu sabi fɔ gi yu wan vaysin we dɛn kɔl Natalizumab, i nɔmal fɔ gɛt bɔku kwɛstyɔn bɔt am. "Us sik dɛn gi dis fɔ?", "I go rili mɛn?", "Ɛni sayd ɛfɛkt de?" Sɔntɛm yu go de wɔnda di sem tin. So, tide, lɛ wi tɔk bɔt dis drɔg we dɛn kɔl Natalizumab insay wan simpul we we yu go ɔndastand.

Us kayn mɛrɛsin na Natalizumab?

Fɔ tɔk am simpul wan, Natalizumab na tritmɛnt. Dat min se i nɔ de mɛn di sik ɔltogɛda, bɔt i de ɛp fɔ kɔntrol di sayn dɛm ɛn ridyus di frɛkuɛns we di sik kin kam. Dɛn kin yuz dis mɛrɛsin mɔ fɔ tu tin dɛn.

1. Fɔ di kɔndishɔn we dɛn kɔl Rilaps Multiple Sclerosis:

Tink bɔt dis we: wi nervɔs sistɛm tan lɛk waya we de kɛr ilɛktrik signal. Insay wan sik we dɛn kɔl multiple sclerosis, di kɔva we de protɛkt (myelin) we de rawnd dɛn nerve fibers ya kin pwɛl. Dɔn dɛn ilɛktrik signal dɛn de nɔ de travul fayn. Dis kin mek yu gɛt sɔm kayn sik lɛk wae yu nɔr kin ebul fɔ waka, yu nɔr kin si fayn, yu nɔr kin ebul fɔ tɔk, ɛn yu nɔr kin no natin. Natalizumab de wok bay we i de kɔntrol dis damej ɛn ridyus di frɛkuɛns we di sik kin wɔs.

2. Fɔ di sik we dɛn kɔl Crohn:

Krohn sik na wan sik wae de mek di dijestiv sistεm, spεshal wan na di intestinal dεm. I kin mek yu gɛt sɔm kayn sik lɛk aw yu bɛlɛ kin at, yu kin blo, ɛn yu kin lɛf fɔ it bɔku bɔku it. Dɔktɔ dɛn kin tɛl yu fɔ tek di mɛrɛsin we dɛn kɔl Natalizumab we ɔda tritmɛnt dɛn nɔ dɔn wok.

Di tin we impɔtant pas ɔl na fɔ mek yu dɔktɔ disayd if dis mɛrɛsin fayn fɔ yu ɛn aw lɔng yu fɔ tek am. So, i rili impɔtant fɔ du wetin i tɛl wi fɔ du.

Dɔktɔ dɛn kin yuz dis mɛrɛsin bak fɔ ɔda sik dɛn. If yu gɛt ɛni kwɛstyɔn bɔt am, aks yu dɔktɔ ɔ fama. Di brand nem fɔ dis mɛrɛsin na Tysabri.

Wetin a fɔ tɛl di dɔktɔ bifo a tek dis mɛrɛsin?

Bifo yu bigin fɔ tek Natalizumab, i impɔtant fɔ tɛl yu wɛlbɔdi tim (i.e., dɔktɔ ɛn nɔs) sɔm infɔmeshɔn, bikɔs da infɔmeshɔn de go ɛp dɛn fɔ disayd if dis mɛrɛsin rayt fɔ yu ɔ if yu nid fɔ tek ɛni spɛshal prɛkoshɔn.

If yu gɛt dɛn tin ya, yu go mɔs tɔk so:

• Immune system problem: If yu gɛt ɛni wikɛd tin ɔr prɔblɛm wit yu bɔdi in sik-fayt sistɛm (immune system), tɛl wi bɔt am. Dis na bikɔs dis mɛrɛsin kin afɛkt di imyun sistɛm bak, so i impɔtant fɔ no bɔt am.
• Wan sik we dɛn kɔl Progressive Multifocal Leukoencephalopathy (PML):Dis na wan bren infεkshכn we nכ kin apin bכku bכt i kin rili denja. If yu dɔn ɛva gɛt dis sik, yu fɔ tɛl wi.
• If yu gɛt alɛji fɔ Natalizumab ɔ ɔda mɛrɛsin, it, day, ɔ tin dɛn we de mek yu nɔ gɛt am: Sɔm pipul dɛn kin gɛt alɛji to sɔm mɛrɛsin dɛn. So if yu bin dɔn gɛt ɛni alɛji fɔ dis mɛrɛsin ɔ ɛni ɔda mɛrɛsin bifo, tɛl yu dɔktɔ.
• If yu gɛt bɛlɛ ɔ yu de tray fɔ gɛt bɛlɛ: Sɔm mɛrɛsin kin ambɔg di pikin we yu gɛt bɛlɛ, so i impɔtant fɔ tɔk to yu dɔktɔ bɔt dis.
• If yu na mama we de gi pikin in mama in bɛlɛ: Sɔm mɛrɛsin kin pas to yu pikin tru in mama in milk. So tɛl yu dɔktɔ bɔt dis bak.

Apat frɔm dɛn tin ya, i rili impɔtant bak fɔ tɛl yu dɔktɔ bɔt ɛni ɔda mɛrɛsin we yu de tek (we dɛn gi yu, we yu de bay, tradishɔnal mɛrɛsin, vaytamɛn, ɛbul prɔdak).

Aw yu kin yuz dis mɛrɛsin?

Dɛn kin gi Natalizumab as infushɔn insay wan vein. I tan lɛk se yu de gi sɔl sɔlvishɔn. Yu nɔ go ebul fɔ du dis na os. Na pɔsin we sabi bɔt wɛlbɔdi biznɛs, lɛk dɔktɔ ɔ nɔs, na ɔspitul ɔ klinik gi yu.

Dɛn kin gi dis mɛrɛsin lɛk wan tɛm insay di mɔnt, bɔt dis kin difrɛn difrɛn wan bay aw yu sik.

We dɛn gi yu dis mɛrɛsin, di famasi go gi yu spɛshal gayd (MedGuide) . Yu go gɛt dis wit ɛvri prɛskrishɔn, ɛvri tɛm we yu gɛt di mɛrɛsin. I rili impɔtant fɔ tek tɛm rid dis. I gɛt tin dɛn bɔt di mɛrɛsin, di bad tin dɛn we kin apin to pɔsin, ɛn tin dɛn we wi fɔ tek tɛm wit. If ɛnitin de we yu nɔ ɔndastand, nɔ fred fɔ aks yu dɔktɔ ɔ fama.

Yu tink se dɛn kin gi pikin dɛn dis mɛrɛsin?

Dɛn nɔ kin gri fɔ yuz dis mɛrɛsin fɔ pikin dɛn. If yu de tink bɔt dis mɛrɛsin fɔ yu pikin, yu fɔ tɔk to yu dɔktɔ we de mɛn pikin dɛn bɔt am.

Wetin fɔ du if yu tek bɔku mɛrɛsin? (Ovadosage) .

Bikɔs dɛn kin gi dis na ɔspitul, di chans fɔ mek dis apin nɔ kin bɔku. Bɔt if yu tink se yu dɔn tek bɔku mɛrɛsin, kɔl pɔyzin kɔntrol sɛnta ɔ imejensi rum wantɛm wantɛm.

Dis mɛrɛsin na fɔ yu nɔmɔ! Dis na sɔntin we di dɔktɔ dɔn tɛl yu fɔ yu sik ɛn yu bɔdi. So, nɔ ɛva sheb dis mɛrɛsin wit ɛni ɔda pɔsin.

Wetin yu kin du if yu mis wan doz fɔ mɛrɛsin?

I rili impɔtant fɔ tek dis mɛrɛsin di rayt tɛm. If yu mis wan apɔntinmɛnt we yu bin dɔn plan fɔ du, kɔl yu dɔktɔ ɔ pɔsin we de kia fɔ yu wɛlbɔdi biznɛs wantɛm wantɛm. Dɛn go tɛl yu wetin fɔ du nɛks. Nɔ disayd fɔ yusɛf.

Us ɔda mɛrɛsin dɛn kin miks (kɔnflikt) wit dis mɛrɛsin?

Dis na pɔynt we rili impɔtant. Sɔm mɛrɛsin dɛn de we kin mek yu gɛt prɔblɛm we yu tek am wit Natalizumab. So, i impɔtant fɔ mek yu dɔktɔ no bɔt ɔl di mɛrɛsin dɛn we yu de tek.

Nɔ tek Natalizumab wit dɛn mɛrɛsin ya:

• Bayolojikal mɛrɛsin dɛm lɛk adalimumab, certolizumab, etanercept, golimumab, ɛn infliximab, kin afɛkt di imyun sistɛm bak, so dɛn kin mek di risk fɔ gɛt siriɔs infɛkshɔn bɔku.

Dɛn mɛrɛsin ya kin intarakt bak wit Natalizumab:

• Azatiɔprin we dɛn kɔl
• Sayklɔspɔrin we dɛn kɔl
• Intafɛron dɛn
• 6-mɛkaptopurin we dɛn kɔl
• Mɛtɔtreksɛt we dɛn kɔl
• Ɔda mɛrɛsin dɛm wae de stɔp yu chans fɔ fɛt wan infekshɔn
• Steroid mεdisin dεm - εgzampl dεm: prεdnison כ kכtison
• Vaysin - Tek tɛm we yu de gɛt layf vaysin, mɔ. Tɔk to yu dɔktɔ bɔt dis.

Dis list nɔ kin gɛt ɔl di mɛrɛsin dɛn. So, tɛl yu dɔktɔ bɔt ɔl di mɛrɛsin dɛn we yu de tek (inklud ɔyl, mɛrɛsin dɛn we yu nɔ de gi yu, ɛn tin dɛn we yu de it), ɛn if yu de smok, drink rɔm, ɔ yuz drɔgs we nɔ rayt. Sɔm tin kin miks wit yu mɛrɛsin dɛm.

Wetin na de tin wae yu fɔ tek tɛm wit we yu de tek dis mɛrɛsin?

We yu de tek dis mɛrɛsin, yu dɔktɔ go de chɛk yu ɔltɛm. Mek shɔ se yu go to yu dɔktɔ di de dɛn we dɛn dɔn sɛtul fɔ yu. Tɛl yu dɔktɔ if yu sik nɔr de bɛtɛ, if i de wɔs, ɔr if i nɔr de kɔntinyu.

Stay away frɔm pipul dɛn we sik. Dis mɛrɛsin kin afɛkt yu imyun sistɛm smɔl, ɛn dis kin mek yu gɛt sik. If yu gɛt sɔm sayn dɛn lɛk fiva, kol, trot we de at, ɔ yu nos we de rɔn, kɔl yu dɔktɔ wantɛm wantɛm fɔ advays. Nɔ go na do fɔ go tek mɛrɛsin yu wan.

Wɔnin we rili impɔtant: risk fɔ gɛt bren infɛkshɔn (PML) .

Dis kin tan lɛk se yu de mek yu fred smɔl, bɔt i impɔtant fɔ no. Insay sɔm sik pipul dɛn, pan ɔl we i nɔ kin apin so ɔltɛm, di mɛrɛsin we dɛn kɔl Natalizumab kin mek dɛn gɛt siriɔs infɛkshɔn na dɛn bren we dɛn kɔl Progressive Multifocal Leukoencephalopathy (PML) . Dis kin ivin kil pɔsin.

So, if yu gɛt ɛni wan pan dɛn sik ya, yu fɔ tɛl yu dɔktɔ wantɛm wantɛm:

• di vishכn de chenj (e.g., di vishכn we de blכr wan wan, dכbl vishכn) .
• I nɔ kin izi fɔ tink (e.g., we pɔsin de agyu, we i nɔ de mɛmba, i nɔ kin izi fɔ mek i disayd fɔ du sɔntin) .
• I nɔ izi fɔ tɔk (e.g., fɔ slɔr wɔd, nɔ ebul fɔ tɔk klia wan) .
• I nɔ izi fɔ waka (e.g., yu nɔ de balans, yu nɔ ebul fɔ waka fayn) .
• I nɔ izi fɔ tinap

If yu nɔ ebul fɔ rich to yu dɔktɔ, go na di imejensi rum wantɛm wantɛm. Nɔ ignore dis. Dɛn sayn ya kin bi ɔ nɔ kin bi sayn fɔ PML. Bɔt i bɛtɛ fɔ mek dɛn tɛst yu.

Wetin na di sayd ɛfɛkt dɛm we dis mɛrɛsin kin gɛt?

Lɛk ɛni mɛrɛsin, Natalizumab kin mek sɔm sayd ɛfɛkt. Nɔto ɔlman kin gɛt dɛn, bɔt i fayn fɔ no bɔt dɛn.

Di sayd ɛfɛkt dɛn we yu fɔ ripɔt to yu dɔktɔ ɔ pɔsin we de kia fɔ yu wɛlbɔdi biznɛs wantɛm wantɛm:

• Alɛji: Na di sayn dɛm lɛk di skin we de rɔsh, it, ayv, swel na yu fes, yu lip, ɛn yu tɔng.
• I nɔ kin izi fɔ yu fɔ blo.
• Di chenj dɛn we de apin na di we aw pɔsin de si tin.
• Chɛst de pen.
• Kɔnfyushɔn, wɔri.
• Dipreshɔn muud, fil lɛk se yu de lɔs yu gladi at.
• Diziz we pɔsin kin gɛt.
• Fɔ fil se yu nɔ gɛt natin; layt ed; fɔdɔm.
• Jɛnɛral sik filin ɔr simptom dɛm we tan lɛk flu.
• I nɔ kin ebul fɔ mɛmba tin igen.
• Uman dɛm we nɔ gɛt dɛn mɔnt pan di de we dɛn fɔ bɔn (Missed menstrual periods).
• Di mɔsul dɛn we wik.
• Prɔblɛm wit balans, tɔk, ɔ waka. (Dis kin bi sayn dɛn bak fɔ PML, so tek tɛm mɔ!)
• Sayn ɛn simptom dɛm fɔ liva injuri: Dak yɔlɔ ɔ brawn urine; fil nɔ fayn, fiva; stɔl dɛn we gɛt pale; i nɔ kin want fɔ it igen; vɔmit; pen na di ɔp rayt say na di bɛlɛ; taya ɔ wik we nɔ kɔmɔn; di yay ɔ di skin we de yɔlɔ.
• Tin dɛn we pɔsin kin tink bɔt fɔ kil insɛf, di we aw pɔsin de fil chenj.
• Brus ɔ blɔd we nɔ kɔmɔn.
• Wik ɔ taya we nɔ kɔmɔn.

Sayd ɛfɛkt dɛn we nɔ kin nid dɔktɔ advays (bɔt dɛn fɔ ripɔt to di dɔktɔ if dɛn kɔntinyu fɔ de ɔ we de mɔna yu):

• Ed de at
• Pen na di jɔyn dɛn
• Mɔsul dɛn we kin kramp
• Mɔsul dɛn kin pen
• Nɔs, fɔ vɔmit
• Pen, rɛd, ɔ iritashɔn na di sayt usay dɛn injɛkt am
• We pɔsin taya

Dis list nɔ kin gɛt ɔl di sayd ɛfɛkt dɛn. If yu notis ɛnitin we nɔ kɔmɔn apat frɔm dɛn tin ya, aks yu dɔktɔ.

Usay yu kin kip dis mɛrɛsin?

Dɛn nɔ go alaw yu fɔ tek dis mɛrɛsin go na os. I de ɛn gi yu na ɔspitul ɔ klinik. So, yu nɔ nid fɔ wɔri bɔt aw fɔ kip am.

Fɔ dɔn, tin dɛn fɔ mɛmba (Take-Home Message) .

Okay, so wi don tok plenti boht Natalizumab. If yu gɛt ɛni ɔda kwɛstyɔn bɔt dis mɛrɛsin, nɔ fred fɔ aks yu dɔktɔ, nɔs, ɔ fama. Dɛn go ɛp yu.

Di tin we impɔtant pas ɔl na fɔ tek di tritmɛnt jɔs lɛk aw yu dɔktɔ tɛl yu, di rayt tɛm, ɛn di rayt we. Yu fɔ no bɔt di sayd ɛfɛkt dɛm, mɔ di sayn dɛm fɔ wan sik we dɛn kɔl PML. If yu notis ɛnitin we nɔ kɔmɔn, tɛl yu dɔktɔ wantɛm wantɛm.

Dis mɛrɛsin kin ɛp yu fɔ kɔntrol yu sik. So, stay strong ɛn jɔyn di dɔktɔ pan dis joyn. Wi de wish yu fɔ wɛl kwik kwik wan!

` Natalizumab, Multiple Sclerosis, Kron sik, PML, Drug sayd ifekt, Imyunotɛrapi, Tysabri