Yu gɛt bɔku bɔku imyun prɔtin dɛn na yu bɔdi? Lɛ wi lan bɔt Polyclonal Gammopathy insay simpul wɔd dɛn!

Yu dɔn ɛva gɛt dɔktɔ tɛl yu se yu gɛt sɔm imyun protɛin dɛn (immunoglobulins) we nɔ de na yu blɔd? Na nɔmal tin fɔ mek yu fred smɔl we yu yɛri sɔntin lɛk dat. Bɔt nɔ wɔri. Tide wi go tɔk bɔt wan sik we dɛn kɔl "Polyclonal Gammopathy." Wi go ɛksplen wetin i bi, wetin mek i kin apin, ɛn wetin yu kin du bɔt am di we we simpul ɛn izi fɔ ɔndastand.

Wetin na dis Polyclonal Gammopathy?

Fɔ tɔk am simpul wan, polyclonal gammopathy na wan sik we sɔm imyun sɛl dɛn na yu blɔd de mek tumɔs antibodies , ɔ immunoglobulins, we na wan kayn prɔtin we de ɛp wi bɔdi fɔ protɛkt insɛf frɔm sik. Tink bɔt dɛn antibodi ya as di bɔdi in yon difens sojaman dɛn. Na dɛn kin fɛt sik ɛn jem we dɛn kam insay.

so, di wכd "polyclonal" min se difrεn tכp dεm fכ imyun sεl dεm de kam togεda εn mek mכr difrεn tכp dεm fכ antibodi dεm. I tan lɛk se difrɛn tim dɛn de wok togɛda, nɔto jɔs di sem kayn sojaman dɛn.

Wetin mek dis de apin? Aw dis kin afɛkt mi?

If yu gɛt polyclonal gammopathy, dat min se yu imyun sistɛm de wok pasmak . I tan lɛk se i de wach ɔltɛm. di men rizin fכ dis na dat yu imyun sistεm de gεt signal כltεm frכm infεkshכn כ wan כtoimyun sik, we de tεl am fכ "mek antibodi, mek antibodi."

Dat min se, polyclonal gammopathy kin bi sayn fɔ ɔda sik we de ɔnda dis sik . Fɔ ɛgzampul, if yu gɛt kansa, ɔ if yu gɛt liva sik, ɔ if yu gɛt ɔtoimyun kɔndishɔn lɛk rεumatoid at, yu kin gɛt dis polyclonal gammopathy. So, we dכkta dεn si dis, dεn de luk fכ, "Wetin mek di imyun sistεm de stimulate so?"

Wetin na di difrɛns bitwin polyclonal ɛn monoclonal gammopathy?

Dis kin tan lɛk se i dip smɔl, bɔt lɛ wi kip am simpul. tu kayn wayt bכdi sεl dεm de na wi bכdi we dεn kכl `B sεl` εn `plasma sεl`. dis na di wan dεm we de mek di antibodi dεm (`Immunoglobulins`) we wi bin tכk bכt bifo.

• Polyclonal Gammopathy: na ya, כl tu di `B sεl dεm` εn `plasma sεl dεm` de kam togεda fכ prodyuz bכku difrεn tכp dεm fכ antibodi dεm. Jɔs lɛk aw difrɛn faktri dɛn kin mek bɔku difrɛn kayn tin dɛn.
• Mɔnoklɔnal Gammopati:wetin de apin ya na se na כnli `plasma sεl dεm` de gεt εn mek tu mכch pan wan tכp antibodi, we dεn kכl `M protin`. Dis na tin we difrɛn smɔl. Dis kin gɛt fɔ du wit kansa kɔndishɔn lɛk `Multiple Myeloma`. כltu, sכm pipul dεm kin gεt wan kכndyushכn bak we dεn kכl `Monoclonal Gammopathy of Undetermined Significance` (MGUS). If dat apin, yu dɔktɔ go de chɛk yu ɔltɛm fɔ si if kansa de kam. So i fayn fɔ no bɔt dat bak.

Impɔtant: Pɔliklɔnal gammopathy nɔ kin bi kansa. Na wan imyun sistɛm we de ansa.

Ɔda nem dɛn de fɔ dis?

Yɛs, dɔktɔ dɛn kin yuz sɔm ɔda nem dɛn fɔ di sik we dɛn kɔl polyclonal gammopathy. Di men wan dɛn na:

• Hypergammaglobulinemia: Dis kin min se di gama globulin (wan kayn antibodi) de go ɔp na di blɔd.
• Polyclonal disease: Dis na ɔda nem bak.

Wetin na di tin dɛm wae kin mek pɔrsin gɛt Polyclonal Gammopathy?

Masta sabi bukman dɛn stil de du risach bɔt di rayt tin we kin mek pɔsin gɛt dis sik. Bɔt i kin bɔku pan pipul dɛn we gɛt sɔm infekshɔn, sik dɛn we dɛn kin gɛt we dɛn de fɛt dɛnsɛf, ɔ kansa na dɛn blɔd. Sɔntɛnde, sɔm mɛrɛsin wae dɛn kin tek fɔ ɔda sik kin mek bak de risk.

Wetin na di sayn dɛm fɔ dis sik?

Bɔrku tɛm, polyclonal gammopathy nɔ kin kɔz ɛni patikyula simptom. Yu kin gɛt sɔm kayn sik bikɔs ɔf de ɔndalayn sik wae mek yu gɛt di gammopathy.

Imajin se yu gɛt nyumonia wit ay fiva ɛn kɔf. Dɔn yu go sho sɔm sayn dɛn we gɛt fɔ du wit da nyumonia de. We di dɔktɔ de trit am, i kin du blɔd tɛst ɛn fɛn dis polyclonal gammopathy kɔndishɔn bay chans. Dat min se, bɔku tɛm dɛn kin fɛn am we yu de luk fɔ ɔda tin.

Dis na sɔntin we vayrɔs ɔ baktri kin pas?

Nɔ, nɔto vayrɔs ɔ baktri de mek pɔsin gɛt polyclonal gammopathy. Na wan imyun sistɛm we de ansa . כltu, polyclonal gammopathy kin kכz bay wan כndalayn vayral כ baktri infεkshכn. Dat min se di vayrɔs ɔ baktri de mek di imyun sistɛm wok.

Aw dɔktɔ dɛn kin no bɔt dis? (Diagnosis) .

Dɔktɔ dɛn kin yuz spɛshal blɔd tɛst mɔ fɔ no if pɔsin gɛt polyclonal gammopathy. Dɛn kɔl dis Sɛrum Protɛin Ilɛktrofɔrɛsis (SPEP) .

If yu dɔktɔ dɔn ɔlrɛdi no se yu gɛt ɔtoimyun sik, infɛkshɔn, liva sik, ɔ kansa, ɔ yu tink se yu gɛt dis kayn sik, i kin du dis `SPEP` tɛst fɔ no ustɛm yu imyun sistɛm de ansa.

Aw di `SPEP` tɛst go ɛp fɔ fɛn dis?

I rili simpul. Di dɔktɔ kin tek blɔd sɛmpul frɔm yu. afta dat, na di lab, dεn de yuz dis mεtכd we dεn kכl `SPEP` fכ separet di difrεn tכp dεm fכ di protin dεm na yu bכdi εn chεk dεn lεvεl.

Dɛn prɔtin lɛvɛl ya kin tɛl yu dɔktɔ bɔku tin bɔt di wɛlbɔdi fɔ yu imyun sistɛm . Fɔ ɛgzampul, dɛn kin gi yu tin fɔ no if yu gɛt liva sik (we kin mek yu gɛt polyclonal gammopathy), ɔ if yu gɛt infekshɔn ɔ kansa.

Ɛni ɔda tɛst dɛn de fɔ no dis?

Yɛs. Sɔntɛnde, if yu dɔktɔ tink se yu gɛt infɛkshɔn na yu sɛntral nervɔs sistɛm, lɛk mɛningaytis, i kin tɛst yu sɛribrospaynal fluid (CSF) bak , bikɔs dɛn kayn infɛkshɔn dɛn de kin mek yu gɛt polyclonal gammopathy bak.

Wetin na di tritmɛnt dɛm fɔ dis?

di imכtant tin fכ כndastand ya na dat polyclonal gammopathy na imyun sistεm rεspכns, nכto sik insεf. So, no dairekt tritmɛnt nɔr de fɔ dis sik.

Yu dɔktɔ go trit di ɔndalayn kɔndishɔn we mek di imyun sistɛm bigin fɔ wok pasmak. Fɔ ɛgzampul, if na infekshɔn mek am, dɛn go trit di infekshɔn. If na wan sik we de mek pɔsin nɔ ebul fɔ fɛt insɛf, dɛn go gi am di rayt tritmɛnt.

We yu de trit di ɔndalayn kɔndishɔn, yu dɔktɔ go chɛk yu imyunoglobulin lɛvɛl bak fɔ si if di polyclonal gammopathy dɔn go dɔŋ ɔ i dɔn go.

Yu tink se dɛn kin stɔp di divɛlɔpmɛnt fɔ Polyclonal Gammopathy?

Bɔt i sɔri fɔ no se, di wan dɛn we de stɔdi bɔt dis nɔ dɔn fɛn we yet fɔ mek dɛn nɔ gɛt dis sik. Bikɔs bɔku tɛm i kin apin as sayd ɛfɛkt fɔ ɔda sik, di bɛst tin fɔ du na fɔ mek yu nɔ gɛt di sik we de ɔnda am.

Aw a go no if a de pan denja fɔ gɛt dis sik?

If yu gɛt sɔm kayn mɛrɛsin, yu de pan ay risk fɔ gɛt polyclonal gammopathy. Sɔm pan dɛn tin ya na:

• Awtoimyun kɔndishɔn: Sɔm ɛgzampul na lupus, rεumatoid at, ɛn Sjogren’s syndrome.
• Blɔd prɔblɛm: Fɔ ɛgzampul, Siklɔs Sɛl Anemia.
• Blɔd kansa: lɛk lukimiya ɛn limfoma.
• Ɔda kansa dɛn: Kidni kansa, Liva kansa, Lɔng kansa, Ovarian kansa.
• Infεkshכn: HIV infεkshכn, Malaria, Mononucleosis, Nyumonia, Tubakulosis.
• Liva sik: Ɔtoimyun Ɛpataytis, Sirosis, Vayral Ɛpataytis.
• If yu dɔn gɛt asbest .

If yu gɛt ɛni wan pan dɛn sik ya, ɔr if yu fil lɛk se yu sik de wɔs, mek shɔ se yu tɔk to yu dɔktɔ. I kin tɛst yu fɔ polyclonal gammopathy, if nid de.

Wetin a kin ɛkspɛkt if a gɛt Polyclonal Gammopathy?

If yu gɛt polyclonal gammopathy, yu kin gɛt smɔl risk fɔ gɛt infɛkshɔn ɛn anemia. Bɔt di gud nyus na dat, if dɛn trit di sik we de ɔnda di sik we mek di gammopathy fayn, di gammopathy ɛn di prɔblɛm dɛn we i kin gɛt kin go.

Dis tin kin apin pas wan tɛm?

yes, polyclonal gammopathy kin apin pas wan tεm, biכs if di כndalayn kכz kam bak, dis imyun rεspכns kin kam bak bak.

If a gɛt dis sik, aw a fɔ kia fɔ misɛf?

Di tin we impɔtant pas ɔl na fɔ fala yu dɔktɔ in instrɔkshɔn dɛn di rayt we. Ɛspɛshali di wan dɛn we de tɔk bɔt fɔ protɛkt yusɛf frɔm infɛkshɔn. Fɔ ɛgzampul, simpul tin dɛn lɛk fɔ wɛr mask we yu de go na say dɛn we pipul dɛn kin bɔku ɛn fɔ was yu an ɔltɛm kin mek big difrɛns.

Mɛsej we dɛn kin kɛr go na os

Okay, so frɔm wetin wi dɔn tɔk bɔt, a op se yu dɔn gɛt gud aidia bɔt Polyclonal Gammopathy ɔ Hypergammaglobulinemia.

• Fɔ tɔk am simpul wan, dis min se yu imyun sistɛm de mek tumɔs imyunoglobulin (antibodies) .
• Dis de sho se yu imyun sistɛm de wok tumɔs . I go mɔs bi se rizin de fɔ dat.
• Yu dɔktɔ go trit di ɔndalayn kɔndishɔn we mek dis, ɛn bɔku tɛm dis gammopathy go bɛtɛ.

So, no panik jos bikos somtin laik dis de fo ripot. Tɔk to yu dɔktɔ ɛn ɔndastand gud gud wan wetin de apin ɛn wetin nid fɔ du. A de wish yu gud wɛlbɔdi!

`polyklonal gammopathy, haypagammaglobulinemia, imyunoglobulin, antibodi, imyun sistεm, SPEP, B sεl, plasma sεl