Yu gɛt inflamɛns bak na yu ‘pauch’? Mek wi tok abaut pouchitis!

Yu don eva geht ileal pouch opareishon? Ɔ pɔsin we yu sabi gɛt wan? Pipul wae gɛt ileal pouch ɔpreshɔn kin gɛt wan sik sɔmtɛm we dɛn kɔl pouchitis. Pan ɔl we i kin mek pɔsin vɛks smɔl, i nɔto natin fɔ wɔri bɔt. Lɛ wi tɔk bɔt am simpul wan we yu go ɔndastand.

Wetin rili na Pouchetis?

Fɔ tɔk am simpul wan, pouchitis na inflamɛns na yu ileal pouch . Mek wi tek wan luk pan wetin na ileal pouch. Fɔ ɛgzampul, sɔm pipul dɛn kin gɛt siriɔs bɔdi we kin mek dɛn pul dɛn wan ol kɔlon ɛn rɛktum. Wi kin kɔl dis ɔpreshɔn totɛl prɔktokɔlektɔmi. Dɔn, dɛn nid fɔ mek nyu we fɔ mek dɔti ɔ stɔl pas kɔmɔt na dɛn bɔdi. na de di ileal pouch de kam in. di sכja dεm de yuz di εnd pan yu sכmכl intestכn, di ileum, fכ mek dis paus, we lεk sכmכl bag. dis na yu kכlon εn rεktum we dεn pul, we min se i de kכlekt εn ol stכl fכ sכm tεm. Dɔn dɛn kin kɔnɛkt dis paus to usay di stɔl de kɔmɔt. sכmtεm i kin kכnεkt to yu an, i kin kכnεkt to yu an, i kin bi J-pouch כ S-pouch, כ lεk K-pouch, we kכnekt to wan spεshal opin na yu bεlε, we dεn kכl stoma. In ɔda wɔd, wan pat pan yu smɔl insay de wok naw lɛk yu kɔlon. So, pouchitis na di sem wit kolεt – inflameshn na di kכlon – כ proctitis – inflameshn na di rεktum – bכt i kin apin pan pipul dεm we gεt ileal pouch. De sayn dɛm kin rili fiba. Di sayn dɛm kin bi wae yu de fil pen na yu bɛlɛ ɛn yu nid fɔ go na tɔylɛt kwik ɛn ɔltɛm. Bɔrku pipul kin gɛt ‘acute pouchitis’, we na inflamɛns we kin kam ɛn go fɔ shɔt tɛm. Bɔt fɔ sɔm pipul dɛn, i kin bi wan sik we dɛn kɔl ‘chronic pouchitis’, we kin de ɔltɛm ɔ we kin kam ɛn go.

Aw kɔmɔn tin fɔ gɛt pɔchitis?

Dɛn se bitwin 25% ɛn 45% pan di pipul dɛm wae dɔn gɛt ileal pouch ɔpreshɔn go gɛt pouchitis sɔm tɛm na dɛn layf . Na lɛk 40% pan pipul dɛm go gɛt am fɔ di fɔs tɛm ɛvri ia. כlso, bitwin 10% εn 20% go divεlכp am bak.

Wetin na di sayn dɛm fɔ Pouchetis?

If yu gɛt pouchitis, yu kin gɛt sɔm kayn sik dɛn lɛk dis.

• Lɔwa bɛlɛ de pen ɛn limp.
• Nid fɔ go na tɔylɛt kwik ɛn ɔltɛm.
• Fɔ gɛt fɔ grap fɔ go na tɔylɛt na nɛt.
• i at fכ kכntrכl di bכdi muvmεnt (bכwel inkontinεns), we min se i de lik sכmtεm.
• I nɔ izi fɔ pas di stɔl, strɛch (dyschezia).
• Fɔ fil lɛk se yu nid fɔ go na tɔylɛt, bɔt nɔ ebul fɔ go (tenesmus).
• Smɔl blɔd na di stɔl.
• Fiva ɔ fil kol.

Wetin na di tin dɛn we kin mek pɔsin gɛt pɔyzin?

Dɔktɔ dɛn tink se di men tin we kin mek pɔsin gɛt pɔyzin na we di kayn bɔdi baktri dɛm we de na yu paus chenj . Tink bɔt am, we wan pat pan yu smɔl intestinal de wok naw lɛk big intestin, i kin gɛt nyu kayn baktri dɛm. Dɛn nyu baktri ya kin kɔmpit wit di baktri dɛm we bin de de bifo. Dis kin mek yu imyun sistεm tink se, "Oh, infεkshכn de ya," εn afta dat i de ansa bay we i de mek yu inflameshn. Sɔm pipul dɛn kin rili gɛt infɛkshɔn. Sɔm kayn baktri dɛm na wi intestinal, if dɛn gi wi di chans, tray fɔ kɔntrol di ɔda wan dɛm ɛn bi kiŋ. Dɛn kɔl dɛn tin ya "pathogenic bacteria." Nɔmal wan, fɔ gɛt sɔm pan dɛn baktri ya na wi intestinal, i fayn, bikɔs ɔda gud baktri dɛn kin kip dɛn in chɛk. bכt afta ileal pouch כpεrayshכn, dis bεlε de chenj, εn dεn "bad" baktri dεm de gεt nyu chans fכ spre dεn pawa. I kɔmɔn fɔ gɛt pouchitis fɔ shɔt tɛm afta dɛn dɔn ɔpreshɔn di ileal pouch. Dɛn kɔl dis pauchitis we kin bigin kwik, ɛn dɛn kin tek am se na bad tin we kin apin we dɛn du di ɔpreshɔn. Bɔku tɛm, i kin bɛtɛ wit antibayɔtik. Bɔt i kin kam bak. Fɔ sɔm pipul dɛn, i kin kɔntinyu fɔ kam bak. Dis na bikɔs sɔm kayn baktri dɛn kin kɔntinyu fɔ kɔntrol ɔda wan dɛn. Yu kin gɛt sɔm kayn akyu pauchitis, ɛn ɛvri tɛm yu kin wɛl wit antibayɔtik. Di prɔblɛm kin kɔmplikt smɔl we yu gɛt pas sɔm episɔd dɛn insay wan ia. Sɔm pipul dɛn kin dipen pan antibayɔtik – dɛn kin kɔl dis kronik antibayɔtik-dipɛndent pouchitis (CADP). Fɔ ɔda pipul dɛn, di antibayɔtik dɛn kin stɔp fɔ wok smɔl smɔl. Dɛn kɔl dis Kronik Antibayɔtik-Rɛsistant Pouchitis (CARP).

Us tin dɛn kin mek pɔsin gɛt krɛse, antibayɔtik-rɛsistant pouchitis (CARP)?

Bɔku rizin dɛn de we kin mek dis ‘CARP’ kɔndishɔn. Sɔm pan dɛn na:

• Inflammatory Bowel Disease ( IBD ): Pipul wae dɔn gɛt proctocolectomy fɔ IBD, lɛk ɔlcerative colitis ɔ Crohn’s disease , kin gɛt bɔrku risk fɔ gɛt pouchitis. Di sem tin dɛn we mek dɛn bin de fɔs kin afɛkt di pɔch.
• Antibayɔtik -rɛsistant baktri dɛm: SɔmBaktri infεkshכn , lεk C. difficile, nכ kin gεt antibaytik. If yu kɔntinyu fɔ yuz antibayɔtik, baktri dɛm we nɔmal wan nɔ kin kɔz sik kin ebul fɔ bia wit antibayɔtik. Dis kin mek bak di baktri dɛm we de na di pɔch nɔ balans.
• Ɔda infɛkshɔn dɛn: Sɔntɛnde, vayral infɛkshɔn, lɛk saytomegalovayrɔs, ɔ fɛns infɛkshɔn, lɛk kandidiasis, kin mek bak di paus inflamɛns.
• Immunosuppression: Yu imyun sistɛm kin wik bikɔs ɔf sɔm sik dɛn ɔ mɛrɛsin dɛn we yu bin dɔn tek bifo tɛm, ɛn dis kin mek yu nɔ ebul fɔ fɛt di infɛkshɔn.
• Kɔntinyu fɔ yuz NSAID : If yu tek pen kil we dɛn kɔl ‘NSAID’ (nonsteroidal anti-inflammatory drugs) lɛk ‘Aspirin’ ɛn ‘ Ibuprofen ’ bɔku tɛm ɛn pasmak i kin pwɛl di layn na yu intestin ɛn di layn na di ‘pouch’.
• blɔd saplai we de ridyus (Ischemia): Pan ɔl we i nɔ kin apin so ɔltɛm, inflamɛns kin apin bak bikɔs di blɔd nɔ kin flɔ to wan pat na di bɔdi. Dis kin bi bikɔs di blɔd vesel dɛn we de gi blɔd kin blok.
• Primary Sclerosing Cholangitis (PSC): Dis na ɔtoimyun sik, we min se di bɔdi in yon imyun sistɛm de atak in yon sɛl dɛn. I kin mek yu biliary trakt gɛt inflamɛns we nɔ de dɔn. lεk IBD, di mεkanism dεm we de mek dis krεse inflameshn kin afekt di paus bak. Pipul wae gɛt dis sik kin gɛt bɔrku risk fɔ gɛt pouchitis.

Wetin na di prɔblɛm dɛn we kin apin we pɔsin gɛt pouchitis?

Akyu pauchitis nɔ kin rili mek big big prɔblɛm dɛn. Bɔt, pɔchitis we nɔ de dɔn, we dɛn nɔ trit, kin mek prɔblɛm. Dɛn tin ya kin bi:

• di chenj dεm we de apin na di bכdi: If di paus inflameshn, i kin mek i at fכ ol di stכl insay, εn we i swel i kin mek i at fכ pas di stכl. Dis kin afɛkt yu bɔdi fɔ lɔng tɛm.
• Ridyus kwaliti layf: Fɔ gɛt prɔblɛm ɔltɛm fɔ go tɔylɛt kin at fɔ liv wit. I kin mek yu gɛt strɛs na yu bɔdi ɛn yu maynd, ɛn i kin ambɔg yu fɔ ɛnjɔy fɔ liv wit ɔda pipul dɛn.
• Strikchɔ na di paus: .If yu gɛt inflamɛns we nɔ de dɔn, dat kin mek di pɔch gɛt skata. Dis skata kin mek di say we di pɔch opin smɔl. I kin mek bak di blɔd nɔ go na di pɔch, ɛn dis kin mek i nɔ ebul fɔ wɛl.
• Irɔshɔn: If yu inflamɛns fɔ lɔng tɛm, i kin mek di layn na di paus rɔtin, ɛn mek ɔlsa. Dɛn ɔlsa ya kin mek blɔd kɔmɔt. Sɔm kayn baktri dɛm we de mek di sik kin pwɛl di intestinal wɔl bak.
• Malabsorption ɛn malnutrition: We di insay layt na di paus dɔn pwɛl, di ebul fɔ absɔb nyutrient frɔm di it we de insay am de ridyus (malabsorption), we kin mek i nɔ gɛt bɛtɛ it.
• Pouch failure: We prɔblɛm dɛn de wit di pouch, i kin leta i nɔ go ebul fɔ yuz am. Dis kin nid fɔ gɛt ɔpreshɔn fɔ pul di paus ɛn divayt di bɔdi to ileostomy.

Aw dɛn kin no se pɔsin gɛt Pouchetis?

Fɔ no bɔt pouchitis kin bigin wit fɔ tɔk bɔt yu sik ɛn wɛl bɔdi histri. Dɔn, yu dɔktɔ go luk insay yu pɔch. Dɛn go yuz wan tin we dɛn kɔl ɛndoskɔp . Dis na tin tiub we gɛt smɔl kamɛra we dɛn tay pan am. Dɛn go pas am tru di paus fɔ luk fɔ inflamɛns ɔ ɔda tin dɛn we nɔ fayn. Dɛn go tek wan tisu sɛmpul bak (bayopsi) tru di ɛndoskɔp ɛn chɛk am fɔ no wetin kin de mek di sik de. Yu dɔktɔ kin yuz ɔda imej tɛst dɛn bak fɔ luk di ɔdasay na di paus ɛn di tin dɛn we dɛn kɔnɛkt to am. Dɛn kin du dis fɔ no if ɔda tin dɛn de we kin mek i gɛt am. Ɔda tɛst dɛn we dɛn kin du na:

• Kontrast pouchography (pouchogram): Dis na wan kayn ɛkstrem rayt. Dɛn kin put wan kɔntrast fluid insay di pɔch fɔ mek pɔsin si am mɔ. i tan lεk barium enema, bכt dεn kin du dis pan di ileal pouch.
• CT skan we dɛn kin du.
• MRI skan (MRI) we dɛn kin du.

Aw fɔ mɛn pɔchitis?

Di fɔs layn tritmɛnt fɔ akyu pauchitis na fɔ tu wiks fɔ tek antibayɔtik . Bɔku pipul dɛn kin bɛtɛ wit dis. If yu nɔr wɛl wit dis, yu dɔktɔ go tray difrɛn antibayɔtik, ɔr wan kɔmbayn antibayɔtik, fɔ lɔng tɛm. If yu stil gɛt di sik afta 4 wik, yu kin gɛt pouchitis we nɔ de tek antibayɔtik. Dɔn yu dɔktɔ go nid fɔ du mɔ tɛst fɔ luk fɔ ɔda tin dɛn we kin mek i apin bifo i disayd di bɛst tritmɛnt.

Wetin na di tritmɛnt fɔ pɔchitis we kin kam bak?

If akyu pauchitis dɔn wɛl wit tritmɛnt ɛn afta dat i kam bak, yu dɔktɔ go kɔntinyu fɔ gɛt di sem tritmɛnt. If de tritmɛnt de wok ɛn de sik nɔr de kam bak ɔltɛm, dɛn kin yuse di sem tritmɛnt. Bɔt if i kam bak pas tri tɛm insay di ia, dɔktɔ dɛn kin tek am se na pɔchitis we de dipen pan antibayɔtik we nɔ de mɛn. Dɛn kin trit am wit lɔng tɛm mentenɛns tɛrapi fɔ mek i nɔ kam bak. Di tritmɛnt fɔ mentenɛns kin inklud:

• Antibayɔtik: If yu tek antibayɔtik we nɔ bɔku, dat kin ɛp fɔ mek yu nɔ gɛt am bak.
• Probiotics: Dis na supamakit we gɛt fayn fayn baktri dɛm we de liv na wi intestinal. Dɛn kin ɛp fɔ mek di baktri dɛn we de na di pɔch balans bak ɛn fɛt di baktri dɛm we de mek di sik.

Wetin na di tritmɛnt fɔ krɛse, antibayɔtik-rɛsistant pouchitis (CARP)?

If yu pauchitis nɔ ɛva bɛtɛ wit antibayɔtik, ɔ if i dɔn bɛtɛ trade bɔt nɔ de bɛtɛ naw, dɔktɔ dɛn kin kɔl am chronic antibiotic-resistant pouchitis (CARP). If na so i bi, di dɔktɔ go fɔs luk fɔ ɛni ɔndalayn kɔz, lɛk sɛkɔndari infɛkshɔn, ɔtoimyun sik, ɔ strɔkchɔral dɛfɛkt na di pɔch. If dɛn nɔ ebul fɔ no klia kɔz, dɛn go trit kronik pouchitis di sem we aw dɛn de trit inflammatory bowel disease (IBD). Na sɔm tritmɛnt dɛn we pɔsin kin gɛt:

• Mesalamin enemas: Mesalamine, we dεn kכl bak 5-aminosalicylic acid (5-ASA), na fכs layn mεdikeshכn fכ כlsεraytiv kolεt. I kin kam lɛk enema we yu kin put insay pɔch.
• Bismuth enemas: Bismuth subsalicylate, di aktiv ingridiɛnt insay Pepto Bismol®, de kam bak as fom enema (bismuth carbomer). Dis kin ɛp fɔ ridyus yu sayn dɛm.
• Kɔtikosterɔyd: Dɛn wan ya na wan kayn mɛrɛsin we de mek pɔsin nɔ gɛt inflamɛns we dɛn kin yuz fɔ mɛn inflamɛns we nɔ de dɔn.
• Immunosuppressants: Dɛn mɛrɛsin ya de ridyus yu imyun sistɛm fɔ ansa. Dɔktɔ dɛn kin gi dɛn tin ya we yu imyun sistɛm de mek yu gɛt inflamɛns we nɔ de dɔn.
• Monoclonal antibodies (biologics): Monoclonal antibodies na protin dεm we mכtalman mek we de wok lεk mכtalman antibodi dεm, we de bכst yu nכmal imyun rεspכns εgεst infεkshכn.
• sכm sכm mכlikul dεm: Dis na nyu dεm we de wok lεk monoklonal antibodi dεm, bכt dεn mek dεm wit sεntetik.
• Fecal microbiota transplant: Dis tritmɛnt na di US Food and Drug Administration (FDA) dɔn gri fɔ trit antibayɔtik-rɛsistant C. diff. Bɔt dɛn kin yuz am bak ɔf-lɛbul fɔ trit antibaytik-rɛsistant pouchitis, ivin if nɔto C. diff mek am. I de ɛp fɔ mek di gut maykrobayɔm we gɛt wɛlbɔdi bak.

Aw lɔng i kin tek fɔ mek pɔchitis wɛl?

Di sayn dɛm fɔ akyu pauchitis kin bigin fɔ bɛtɛ insay sɔm dez afta dɛn bigin fɔ trit di antibayɔtik. Bɔt i impɔtant fɔ dɔn di ful tu wiks kɔs fɔ antibayɔtik, ivin if yu fil fayn. Yu fɔ go to yu dɔktɔ afta di tritmɛnt dɔn. Dɛn go want fɔ luk insay yu paus bak fɔ mek shɔ se di inflamɛns dɔn go ɔlsay.

Yu tink se dɛn kin ebul fɔ avɔyd Pouchetis?

Sɔm pruf dɛn sho se probayotik kin ɛp fɔ mek pɔchitis nɔ kam afta dɛn dɔn ɔpreshɔn am ɔ fɔ mek i nɔ kam bak afta dɛn dɔn trit am fayn. Sɔntɛm dɛn nɔ kin wok ɔltɛm, bɔt dɛn kin wok fɔ yu. Sɔntɛnde, dɔktɔ dɛn kin gi yu wan spɛshal probayotik blɛnd (lɛk di DeSimone fɔmyulashɔn). Di kayn probayotik we yu de tek impɔtant, so i impɔtant fɔ tɔk to yu dɔktɔ.

Wetin yu kin ɛkspɛkt if yu gɛt pouchitis?

If yu gɛt pouchitis afta ileal pouch ɔpreshɔn – ivin if i apin sɔm tɛm – gud chans de fɔ mek dɛn trit am fayn fayn wan wit antibayɔtik. Sɔm pipul dɛn kin nid fɔ tek antibayɔtik fɔ lɔng tɛm pas ɔda pipul dɛn. If yu gɛt di episɔd ɔltɛm, yu kin nid fɔ gɛt tritmɛnt fɔ lɔng tɛm wit antibayɔtik ɔ probayotik. Fɔ smɔl pipul dɛm wae gɛt pouchitis, nɔr pan dɛn tritmɛnt ya nɔr kin woke. If yu kɔntinyu fɔ gɛt pouchitis ɛn i nɔ de ansa to antibayɔtik tritmɛnt, yu dɔktɔ go luk fɔ di ɔndalayn kɔz dɛm fɔ inflamɛns, lɛk ischemia, yuz NSAID, ɔ wan sik we de ambɔg yu bɔdi. If dɛn nɔr ebul fɔ fɛn sɛkɔndari kɔz, dɛn go no se na chronic antibiotic-resistant pouchitis (CARP). Dɔktɔ dɛn go tɔk bɔt difrɛn tritmɛnt dɛn fɔ CARP. Dɛn go wok wit yu fɔ fɛn di wan we bɛtɛ fɔ yu.

Sɔntɛnde, if di prɔblɛm dɛn we de wit di pɔch pas di bɛnifit dɛn, yu kin disayd fɔ pul di pɔch fɔ liv layf we nɔ gɛt sik. Dat na opshɔn bak.

Fɔ it ɛn drink kin afɛkt pɔchitis?

Yɛs, te to sɔm mak. Sɔm pruf dɛn sho se if yu it nɔ gɛt bɔku antiɔksidant , yu kin gɛt mɔ risk fɔ gɛt pouchitis. Antiɔksidant dɛn kin de na bɔku frut ɛn vɛjitebul dɛn bay insɛf. Dɛn kɔmpawnd ya de ɛp fɔ mek di kemikal dɛn we de na wi bɔdi we dɛn kɔl fri radikal nɔ gɛt pawa. we fri radikal dεm de kכmכt na di bכdi, dεn kin pwεl di sεl dεm εn kכntribyut fכ inflameshn. Antioksidant frɔm it kin wok fayn pas supamakit. Bɔt if yu de sɔfa wit pouchitis simptom, fɔ ridyus di fayba we de na yu it kin ɛp. Dɔktɔ dɛn kin se yu fɔ it tin dɛn we nɔ gɛt bɔku FODMAP . Dis de ridyus di it dεm we yu gכt baktri dεm lɛk fכ it, inklud fayv. If yu kɔt dɛn it ya fɔ sɔm tɛm, dat kin ɛp fɔ ridyus di sik dɛn we yu kin gɛt na yu bɔdi. Bɔt as tɛm de go, yu fɔ tray fɔ ad difrɛn it dɛn bak to yu it.

Fɔd dɛn we de ɛp fɔ mek yu nɔ gɛt pouchitis:

Mek shɔ se yu de gɛt inof antiɔksidant. Yu kin gɛt dɛn tin ya bay we yu it difrɛn difrɛn frut ɛn vɛjitebul dɛn. Sɔm pan di bɛst it dɛn we gɛt bɔku antiɔksidant na:

• Apul
• Bɛri (lɛk strawberry, bluberi) .
• Greps
• Plum dɛn we dɛn dɔn dray (Prunes) .
• Di kayn bins dɛn we dɛn kin mek
• Atichɔk dɛn
• Russet potato dɛn we dɛn kin mek
• Dak grin lif vegjetabul (lɛk spinach, kale) .

Fɔ ad ful it dɛn to yu it, mɔ di it dɛn we dɛn mek wit plant, na di men prinsipul fɔ it we de mek yu nɔ gɛt inflammatory. Antiɔksidant na jɔs wan rizin.

Fɔd dɛn we yu nɔ fɔ it we yu gɛt pouchitis (fɔ ridyus di sayn dɛm):

Fɔ ridyus di sayn dɛm we de sho se yu gɛt pouchitis, dɔktɔ dɛn kin se yu fɔ it tin dɛn we nɔ gɛt bɔku FODMAP, at ɔl te yu no us FODMAP yu gɛt alɛji to. Di kɔmɔn FODMAP dɛn inklud:

• Fruktoz (shuga we de insay frut) .
• Laktoz (shuga we de insay milk) .
• Yabas
• Wait anɔynt
• Di kayn bins dɛn we dɛn kin mek
• Wit

Di it we nɔ gɛt bɔku FODMAP na it we dɛn kin it fɔ shɔt tɛm. Yu kin pul sɔm it dɛn na yu it, fɛn ɔda tin dɛn we kin mek yu it dɛn, dɔn yu kin put dɛn bak smɔl smɔl ɔnda di gayd we dɔktɔ de gayd yu.

Fɔ dɔn, di mɛsej we dɛn kin kɛr go na os

If yu gɛt ileal pouch, yu kin gɛt pouchitis sɔm tɛm. Nɔto ɔlman kin gɛt am, bɔt di wan dɛn we kin gɛt am kin gɛt am pas wan tɛm. I kin mek yu at pwɛl fɔ gɛt prɔblɛm wit yu bɔdi we de kɔntinyu ivin afta dɛn dɔn pul bɔku pan dɛn kɔlon. De gud nyus na dat fɔ bɔrku pipul dɛm, pouchitis na prɔblɛm wae kin kam wan wan tɛm nɔmɔ, ɛn i kin izi fɔ trit pas de krɛse sik wae dɛn kin gɛt bifo. Kronik antibayɔtik-rɛsistant pouchitis (CARP) kin trik smɔl. Sɔntɛnde, i kin gɛt fɔ du wit wan sik we bin dɔn de bifo we de mek pɔsin gɛt bɔdi we nɔ de dɔn. Fɔ trit am kin rili at fɔ du. Bɔt if yu tray smɔl, yu kin fɛn wan kɔmbayn tritmɛnt we go wok fɔ bɔku pipul dɛn. Mɛmba se nɔto yu wangren de. Tɔk wit yu dɔktɔ opin wan ɛn aks ɛni kwɛstyɔn we yu gɛt. If yu gɛt di rayt gayd ɛn tritmɛnt, yu kin liv fayn wit dis sik.