Sɔntɛnde yu kin fil lɛk se sɔntin na yu bɔdi nɔ de wok fayn? Sɔm strenj sik dɛn de, we dɛn nem kin mek pɔsin fred smɔl. Wan pan dɛn kayn sik ya we dɛn nɔ kin yɛri bɔt, bɔt we impɔtant fɔ no bɔt, na Pseudohypoparathyroidism (PHP). Pan ɔl we i go tan lɛk se di nem lɔng smɔl, lɛ wi kip am simpul.
Wetin na pseudohypoparathyroidism?
Fɔ tɔk am simpul wan, dis na tin we nɔ kin apin so ɔltɛm we pɔsin kin gɛt we i kam pan jɛnɛtiks . Wi gɛt smɔl smɔl gland dɛn na wi bɔdi we dɛn kɔl paratayroyd gland. Dɛn tin ya kin mek wan ɔmon we dɛn kɔl Parathyroid Hormone (PTH). Dis PTH ɔmon rili impɔtant fɔ wi bɔdi. Bikɔs, dis ɔmon de ɛp fɔ mek di Kalsiɔm, Fɔsfɔr, ɛn Vitamin D gɛt di rayt lɛvɛl na wi blɔd.
Naw, yu no wetin kin apin to pɔsin we gɛt pseudohypoparathyroidism (PHP)? ivin if dεn paratayroyd gland dεm de prodyuz PTH כmon nכmal wan, di sεl dεm na dεn bכdi nכ de rεspכnd to am fayn, we min se dεn nכ kin "rεkכgnεz" am. I tan lɛk se pɔsin de tɔk to yu bɔt yu nɔ ebul fɔ yɛri dɛn. Wi kɔl dis Paratayroyd Ɔmon Risistɛns .
Wetin kin apin bikɔs ɔf dat? di kalsiכm lεvεl na di bכdi de dכn, we di fכsfכr lεvεl de go כp. Dis nɔ balans kin mek di mɔsul dɛn de shek shek, i kin mek i nɔ gɛt bɛtɛ trɛnk, i kin gɛt prɔblɛm wit in tit.
I impɔtant fɔ no se dis sik we dɛn kɔl PHP difrɛn frɔm wan sik we dɛn kɔl Hypoparathyroidism. Pipul wae gɛt haypoparathyroidism nɔ kin prodyuz inof PTH ɔmon fɔ bigin. Bɔt insay PHP, dɛn kin mek di ɔmon, bɔt di bɔdi nɔ de yuz am.
Wetin na di men kayn PHP?
Bɔku men kayn dɛn de fɔ dis PHP stetɔs. Lɛ wi si wetin dɛn bi.
PHP-1 tayp
Dis na di kayn PHP we kɔmɔn pas ɔl . apat frכm di PTH hכmon rεsistεns we wi bin dכn tכk bכt, yu kin si sכm chenj dεm na di skel sistεm. Fɔ ɛgzampul:
- Di fes we de rawnd
- Di ayt we dɔn go dɔŋ (we i shɔt) .
- Nek de pen
- Fraktrɔs na di an ɛn fut
Dɔktɔ dɛn kɔl dis kɔmbayn pan di sik dɛn Albright Hereditary Osteodystrophy (AHO) . Pipul dεm we gεt PHP-1 gεt di kכndishכn biכs fכ wan vεryכnt fכ wan jin we dεn kכl `GNAS` we dεn kin gεt frכm wan pan dεn mama εn papa.
PPHP (Pseudopseudohaypoparatayroydism) we de mek pɔsin gɛt sik.
Dis na wan limited fom fɔ PHP-1. Pipul wae gɛt PPHP (Pseudopseudohypoparathyroidism) kin gɛt di bɔdi wae dɛn kin si na AHO (lɛk dɛn fes rawnd ɛn shɔt), bɔt dɛn nɔr kin gɛt PTH ɔmon rɛsistɛns . dis min se dεn kalsiכm εn fכsfכr lεvεl na nכmal.
PHP-2 tayp
Pipul dεm we gεt PHP-2 gεt PTH כmon rεsistεns, we min se dεn gεt lכw kalsiכm εn hכy fכsfכr. Bɔt dɛn nɔ gɛt di bɔdi (lɛk rawnd fes ɛn shɔt ayt) we dɛn kin si na AHO. Risach pipul dεm nכ dכn fכ no yet εksεkεt us jεnεtik dεfεkt de mek dis kayn PHP-2.
Wetin na di sayn dɛm fɔ PHP?
Di sayn dɛm fɔ PHP kin difrɛn frɔm wan pɔsin to ɔda pɔsin . Dis min se nɔto ɔlman go gɛt di sem sayn. Sɔm sayn wae kin kam pan pɔrsin wae gɛt dis sik na:
- Di mɔsul dɛn we de spam
- Mɔsul kramp ɔltɛm : Na filin lɛk se dɛn de pul yu leg.
- Di an ɛn fut dɛn we nɔ gɛt bɛtɛ trɛnk ɔ we de swɛt
- Di sik dɛn we kin mek pɔsin sik
- Dilay we yu de mek yu tit
- We di tut inɛmel wik
- Lɔw blɔd prɛshɔn
- Brittle ia ɛn nel dɛn
- Wɔri
- Pwɛl at
Pipul wae gɛt PHP-1 kin gɛt ɔda simptom dɛm wae kin kam wit di Albright hereditary osteodystrophy (AHO) kɔndishɔn wae wi bin dɔn tɔk bɔt. Sɔm pipul dɛm wae gɛt PHP kin gɛt dɛn sik ya bak:
- Di fes we de rawnd
- Short stature (shɔt ayt) .
- Nek de pen
- bon dεm na di an εn fut : di kכl dεm, spεshal wan dεm na di fכs εn 5 finga dεm kin lεk se dεn tכn insay.
- Fat pasmak : I min se yu fɔ gɛt bɔku bɔku bɔdi.
- Vision impairments : tin dεm lεk katarakt, blכr vishכn, εn sεnsitiviti to layt.
- Bɔni bɔmp dɛn ɔnda yu skin
- Divεlכpmεnt delay : sכm pikin dεm kin gεt sכm divεlכpmεnt delay.
Wetin na di tin dɛn we kin mek pɔsin gɛt PHP?
di men tin we de mek dis sik na di vεryushכn na wi jin dεm, spεshal wan na di jin we dεn kכl `GNAS` . Sɔm pipul dɛn kin gɛt am frɔm dɛn mama ɛn papa . Dat min se na tin we pɔsin kin gɛt frɔm in mama ɛn papa. Bɔt sɔmtɛm dis sik kin apin wae yu nɔr gɛt ɛni famili histri ɛn dɛn nɔr kin no ɛni rizin.
Dɛn kin no PHP we dɛn smɔl ɔ we dɛn smɔl , bɔt sɔntɛnde i kin apin we dɛn big.
Wetin na di pɔsibul kɔmplikeshɔn dɛn we PHP kin gɛt?
If yu gɛt PHP, yu go gɛt ɔda ɛndokrin sistɛm disɔda . Dɛn prɔblɛm ya we gɛt fɔ du wit ɔmon kin mek yu gɛt sɔm sayn dɛn lɛk we yu nɔ gɛt bɔku ɛnaji ɛn we yu nɔ want fɔ du mami ɛn dadi biznɛs.
Sɔm pipul dɛm wae gɛt PHP kin gɛt bɔrku risk fɔ gɛt kɔndishɔn lɛk:
- Wan sik we dɛn kɔl Parkinsonism: Fɔ sho sɔm sayn dɛm we fiba di sik we dɛn kɔl Parkinson.
- Difεlεnt wit fayn mכtalman skil dεm : Dis min se i at fכ du fayn fayn wok dεm lεk fכ bכtכm כ rayt.
- Carpal Tunnel Syndrome : Ɛspɛshali fɔ di wan dɛn we gɛt PHP-1. Dis na kכndyushכn we wan nεv na di an de kכmprεs, we de mek di an sכmtεm sכmtεm εn i de fil pen.
- Stɛnɔsis we de na di spaynal
- Slip apnea : Ɛspɛshali pan pikin dɛn.
Aw dɔktɔ dɛn kin no if pɔsin gɛt PHP?
If yu sɔspɛkt se yu gɛt PHP, yu dɔktɔ go fɔs du yu bɔdi ɛgzam . Dɛn go aks bak bɔt yu famili istri . Dɔn dɛn kin du sɔm ɔda tɛst dɛn fɔ no if dɛn dɔn no di sik. Dɛn tin ya na:
- Blɔd tɛst : Fɔ mɛzhɔ di ɔmon lɛvɛl, mɔ di kalsiɔm, fɔsfɔr, ɛn PTH lɛvɛl.
- Yurin tεst : Chεk di lεvεl dεm we di kalsiכm εn fכsfכr de insay di urine.
- jεnεtik tεst : Chεk fכ chenj dεm na di `GNAS` jin.
- Ilɛktrokardiogram (EKG) : I de chɛk fɔ si if di at bit nɔ de bi.
- Han X-ray : Chɛk fɔ brok bon ɛn ɔda chenj dɛn.
- CT Scan (CT - Computed Tomography scan) : Fɔ si if ɛni chenj de na di bren.
Na bays pan di infɔmeshɔn we dɛn gɛt frɔm dɛn tɛst ya, di dɔktɔ kin kɔnfɔm di PHP stetɔs kɔrɛkt wan.
Aw dɛn kin trit PHP?
No mɛrɛsin nɔ de fɔ dis sik yet . Bɔt nɔ wɔri. If yu gɛt di rayt tritmɛnt ɛn mɛnejɛmɛnt, yu kin kɔntrol yu sik ɛn liv nɔrmal layf.
Di men gol fɔ tritmɛnt na fɔ mek yu kɔntinyu fɔ gɛt di kɔrɛkt lɛvul fɔ di kalsiɔm ɛn fɔsfɔr na yu blɔd . If yu kɔntinyu fɔ gɛt dɛn kayn sik ya, dat kin ridyus di sik bad bad wan. Dis na tritmɛnt fɔ ɔl yu layf .
Di tritmɛnt we dɛn kin pik kin bi:
- Kalsiɔm ɛn vaytamɛn D sɔpɔtmɛnt : insay pil ɔ likwid fɔm.
- Calcitriol capsules : Dis na mɛrɛsin we de mek di kalsiɔm we de na di bɔdi bɔku.
- Injɛkshɔn we dɛn kin gi wit kalsitriɔl
- Grɔw ɔmon ɔ tayroyd ɔmon riplesmɛnt tɛrapi : if nid de.
- Di it we gɛt bɔku kalsiɔm, we nɔ gɛt bɔku fɔsfɔr : As pɔsin we sabi bɔt it advays.
Di tin we impɔtant pas ɔl na fɔ tek tɛm fala di dɔktɔ dɛn advays ɛn du tɛst di rayt tɛm.
Ustɛm a fɔ go to dɔktɔ?
If yu gɛt PHP, i impɔtant fɔ go to yu dɔktɔ ɔltɛm fɔ mek dɛn chɛk yu kalsiɔm ɛn fɔsfɔr lɛvɛl . Dis monitarin ɔltɛm go ɛp fɔ kip ɔltin ɔnda kɔntrol.
If yu gɛt siriɔs sik lɛk fɔ blo wantɛm wantɛm, fɔ mek yu mɔsul dɛn de shek shek bad bad wan, ɔ fɔ mek yu sik , go na di ɔspitul imejensi rum we de nia yu wantɛm wantɛm ɔ kɔl 1990.
Wetin yu kin ɛkspɛkt we yu de liv wit di PHP sityueshɔn?
If yu gɛt PHP, yu fɔ kɔntinyu fɔ wok wit yu Praymari Keya Dɔktɔ . Bikɔs PHP kin afɛkt bɔku difrɛn pat dɛm na yu bɔdi, yu kin nid fɔ go to sɔm spɛshal pipul dɛm fɔ mɛn yu patikyula sayn dɛm. Yu mɛdikal tim kin gɛt:
- Endocrinologists : Na spɛshal pipul dɛn we sabi bɔt ɔmon.
- Ɔtpidik ɔspitul dɛn : Fɔ prɔblɛm dɛn we gɛt fɔ du wit bon.
- Pikin dɛn : If na pikin.
- Nyurolɔjis : Fɔ prɔblɛm dɛn we gɛt fɔ du wit di nervɔs sistɛm.
- Di wan dɛn we de mɛn pipul dɛn we gɛt bɔdi
- Ɔkupeshɔn tɛrapist dɛn
- Di wan dɛn we sabi bɔt it
- Dɛntist dɛn
- Di wan dɛn we de stɔdi bɔt di jɛnɛtiks
- Spɛshal pipul dɛn we sabi aw fɔ mɛn di pen
Yu go mɔs gɛt fɔ tek dɛn supamakit dɛn de fɔ di res ɔf yu layf .
di divεlכpmεnt εn intellektual abiliti dεm kin difrεn bכku bכku wan dipכnt pan di kayn sik εn aw i siriכs. Bɔt bɔku tɛm, pipul dɛn we gɛt PHP kin gɛt nɔmal layf we yu kɔmpia am wit pipul dɛn we nɔ gɛt PHP . Yu dɔktɔ kin tɛl yu wetin fɔ ɛkspɛkt bay aw yu sik.
Bikɔs PHP na wan sik we nɔ kin apin so ɔltɛm, i kin at fɔ fɛn ɔda pipul dɛn we gɛt di sem kɔndishɔn lɛk yu . Sɔntɛnde, i kin fil bak se na in wangren de. If yu ɔ yu pikin gɛt PHP, tɔk to yu dɔktɔ bɔt sɔpɔt grup ɛn ɛdyukeshɔn risɔs . Dɛn tin ya kin ɛp yu fɔ fɛn we fɔ mek yu gɛt bɛtɛ sayn ɛn ɔl yu layf.
Mɛsej we dɛn kin kɛr go na os
Okay, so lɛ wi tek wan luk pan sɔm tin dɛm fɔ mɛmba bɔt di pseudohypoparathyroidism (PHP) we wi dɔn de tɔk bɔt.
- PHP na wan jεnεtik kכndyushכn we nכ kin apin we di bכdi nכ de rεspכnd fayn to paratayroyd כmon (PTH).
- dis kin mek di kalsiכm we de na di bכdi dכn εn di fכsfכr de bכku.
- Bɔku men kayn dɛn de : PHP-1, PHP-2, ɛn PHP-3.Yɛs. PHP-1 kin mek chenj na di bon dεm we dεn kכl AHO.
- Difrɛn sayn dɛn kin apin, lɛk we yu mɔsul dɛn kin twitch, yu nɔ kin fil fayn, yu kin gɛt prɔblɛm wit yu tit, yu kin shɔt, ɛn yu fes kin rawnd .
- di men kכz na di mכtεshכn na di `GNAS` jin .
- Pan ɔl we dɛn nɔ gɛt kɔmplit mɛrɛsin, dɛn kin kɔntrol di sik dɛn wit tritmɛnt fɔ ɔl dɛn layf (kalsiɔm, vaytamɛn D, spɛshal it).
- I impɔtant fɔ mek dɛn de chɛk yu dɔktɔ ɔltɛm ɛn fɔ sɔpɔt spɛshal dɔktɔ dɛn.
- Bɔku pipul dɛn kin liv nɔmal layf .
- Di ɛp we sɔpɔt grup dɛn kin gi rili impɔtant fɔ mek yu gɛt strɔng maynd.
Nɔ fɔgɛt, nɔto yu wangren de. Pan ɔl we dis na tin we nɔ kin apin so ɔltɛm, dɛn kin ebul fɔ mɛn am fayn if dɛn gi yu di rayt advays ɛn sɔpɔt. Mɛmba se dɔktɔ dɛn, fambul dɛn, ɛn padi dɛn de fɔ yu we yu nid trɛnk.
` Pseudohypoparathyroidism, PHP, paratayroyd ɔmon, kalsiɔm, fɔsfɔr, jɛnɛtik sik dɛn, AHO
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