Yu kin fil se yu taya ɔltɛm, yu ed kin tɔn, ɔ i nɔ kin izi fɔ yu fɔ waka ɔp stej? Sɔntɛm sɔmbɔdi go dɔn aks yu se, "Wetin mek yu de pale so dɛn tɛm ya?" Bɔku tɛm, dɛn tin ya kin sho se pɔsin nɔ gɛt bɛtɛ blɔd. Bɔt tide wi go tɔk bɔt wan sik we nɔ kin apin so ɔltɛm we kin mek pɔsin gɛt anemia, we bɔku pipul dɛn nɔ yɛri bɔt, bɔt wi fɔ no bɔt. Dat na Pure Red Cell Aplasia , ɔ PRCA fɔ shɔt tɛm.
Fɔ tɔk am simpul wan, wetin na Pure Red Cell Aplasia (PRCA)?
Imajin se insay wi big bon dɛn, we na di bon mɛro, tan lɛk big faktri we de mek blɔd. Dis faktri na di say we dɛn de mek di tri kayn sɛl dɛn we wi bɔdi nid, we na rɛd blɔd sɛl, wayt blɔd sɛl, ɛn pletlɛt. di men wok we rεd bכdi sεl dεm de du na fכ pik כksijεn we de kam insay wi lכng we wi de blo εn sheb am to כl di כda sεl dεm na di bכdi.
Naw, insay wan kɔndishɔn we dɛn kɔl Pure Red Cell Aplasia (PRCA) , di prodakshɔn layn na di faktri we de mek rɛd blɔd sɛl dɛn kin stɔp fɔ wok wantɛm wantɛm. di prodakshכn fכ כda kayn sεl dεm, dat na wayt blכd sεl dεm εn pletlet dεm, nכ kin chenj bכku. We na di rɛd blɔd sɛl nɔmɔ we dɛn de mek dɔn stɔp, di nɔmba fɔ di rɛd blɔd sɛl dɛn na di bɔdi kin go dɔŋ smɔl smɔl. Dis na wetin wi kɔl anemia . We nɔr gɛt bɛtɛ sɛl fɔ kɛr ɔksijɛn go ɔlsay na di bɔdi, di sayn dɛm we wi bin dɔn tɔk bɔt, lɛk fɔ taya ɛn fɔ wik, kin bigin fɔ sho.
Wetin na di sayn dɛm wae de sho se pɔrsin gɛt PRCA?
PRCA na wan sik wae kin mek pɔrsin gɛt siriɔs anemia, so di sayn dɛm kin klia pas di wan dɛm wae dɛn kin si wit nɔmal anemia.
| Di sayn we de sho se di sik de | Wan simpul ɛksplen |
|---|---|
| Taya | Fɔ fil so taya dat yu nɔ go ivin ebul fɔ pas di de, nɔto fɔ tɔk bɔt fɔ du sɔm wok dɛn we de mek yu tranga. |
| I nɔ izi fɔ blo (Dyspnea) . | Fɔ fil se yu nɔ gɛt bɛtɛ briz we yu de du nɔmal tin dɛn, we yu de waka, ɔ we yu de klaym stej. |
| Diziz we pɔsin kin gɛt | Fɔ fil diziz bikɔs di ɔksijɛn we di bren nid de dɔŋ. |
| Pale skin | di skin, di lip dεm, εn di nel dεm kin tan lεk bεlε biכs di rεd bכdi sεl dεm nכ de, we de gi di skin in pink kכla. |
| Ɛd we de at | Ɛd pen we kin kam bikɔs di ɔksijɛn we de na di bren nɔ de wok fayn. |
| Fɔ yɛri nɔys na yu yes (Pulsatile Tinnitus) . | Fɔ yɛri sawnd na di yes to di ritm we di at de bit. |
| Chɛst pen (Angina) . | Chɛst pen we kin kam bikɔs ɔksijɛn nɔ de go na di at mɔsul. |
Wetin mek dis kayn tin we nɔ kin apin so ɔltɛm kin apin?
No wan rizin nɔ de fɔ mek PRCA. Bɔku tin dɛn de we kin mek i apin. Sɔmtɛm i kin apin bak as sayd ɛfɛkt fɔ ɔda ɔndalayn mɛdikal kɔndishɔn.
- Autoimmune Diseases: Fɔ tɔk am simpul wan, dis na we wi bɔdi in difɛns sistɛm (immune system) kin mistek atak wi yon bɔdi. sכmtεm dis atak kin tכk bak to di sεl dεm na di bon mכro we de mek rεd bכdi sεl dεm. fכ egzampl, PRCA kin apin wit sik dεm lεk `(Systemic Lupus Erythematosus - SLE)` εn `(Rheumatoid Arthritis)`.
- Blɔd Kansa: Risk de fɔ mek yu gɛt PRCA wit sɔm kayn kansa dɛn we gɛt fɔ du wit blɔd, mɔ we dɛn kɔl Chronic Lymphocytic Leukemia (CLL) ɛn Large Granular Lymphocytic Leukemia (LGL).
- Kansa tכmכro: Taymoma na kansa tכmכro we de divεlכp na di taymus gland na di chεst. Dis kin bi bak wan big tin we kin mek PRCA.
- Vayral Infεkshכn: Parvovirus B19Di vayrɔs we de mek PRCA na di men tin we de mek pɔsin gɛt PRCA. dis vayrus de atak di stεm sεl dεm na di bon mכro we de mek rεd bכdi sεl dεm dεn wan dεm. I kin kam bak wit HIV, Epstein-Barr vayrɔs, ɛn epataytis vayrɔs.
- Baktri Infεkshכn: Sivεr baktriyal infεkshכn, lεk TB, kin bכku bak wit PRCA.
- Sɔm mɛrɛsin dɛn: PRCA kin apin bak as sayd ɛfɛkt fɔ sɔm mɛrɛsin dɛn.
- Bεlε: Na sכm uman dεn kin gεt PRCA fכ sכm tεm we dεn bεlε. Bɔt di sik kin sɔlv fɔ insɛf afta dɛn bɔn am.
Aw dɔktɔ kin no bɔt dis sik?
If yu gɛt di sayn dɛn we wi dɔn tɔk bɔt, dɔktɔ go chɛk yu fɔs ɛn afta dat i go tɛl yu fɔ du bɔku tɛst fɔ no if yu gɛt di sik.
- Complete Blood Count (CBC): Dis de sho di nɔmba fɔ di rɛd blɔd sɛl dɛn, di wayt blɔd sɛl dɛn, ɛn di pletlɛt dɛn we de na yu blɔd. Insay PRCA, di nɔmba fɔ di rɛd blɔd sɛl dɛn rili smɔl.
- rεtikulכsayt kכnt: dis de mכsu di nכmba fכ di rεd bכdi sεl dεm we nכ machכ we dεn nyu fכm na di bon mכro εn ad to di bכdi. Insay PRCA, dis nɔmba sɛf rili smɔl.
- Peripheral Blood Smear: Dɛn kin tek wan drop pan blɔd ɛn chɛk am ɔnda maykroskɔp fɔ chɛk di shep ɛn di kayn we aw di rɛd blɔd sɛl dɛn tan.
- Parvovirus B19 Test: Dɛn kin du dis tɛst if dɛn tink se gɛt vayral infɛkshɔn.
- CT Scan: dεn kin du dis tεst if dεn sכspεshכn fכ tכmכro lεk ``Thymoma'' na di chεst.
- Bone Marrow Aspiration/Biopsy: Dis na di test we impɔtant pas ɔl fɔ kɔnfɔm di sik. sכm sכm nidul fכ pul wan sεmpl fכ bon mכro frכm wan ples lεk di hip bon כnda anεsthεsia. insay PRCA, dis kin kכnfכm se di bon mכro dεn dכn kכmplit di sεl dεm we de fכm rεd bכdi sεl dεm.
Aw dɛn kin trit PRCA?
Dɛn kin trit PRCA bay we dɛn no wetin de mek di sik kam ɛn adrɛs da kɔz de.
Di tin we impɔtant pas ɔl na dat, yu fɔ jɔs du dis tritmɛnt ɔnda yu dɔktɔ in sɔpɔtishɔn. If yu tek mɛrɛsin fɔ yusɛf, dat kin mek yu gɛt siriɔs prɔblɛm dɛn.
Bɔku we dɛn de fɔ trit pɔsin:
- Immunosuppressants: If di tin we mek di sik na prɔblɛm wit di we aw di imyun sistɛm de wok, dɛn kin gi drɔgs lɛk `(Corticosteroids)` (e.g. Prednisone) ɛn `(Cyclosporine)` fɔ kɔntrol am.
- Blɔd Transfyushɔn:If di blɔd kɔnt rili smɔl ɛn di sayn dɛn we de sho se di sik bad bad wan, dɛn kin gi pɔsin blɔd fɔ mek i fil fayn kwik kwik wan. Bɔt dis na sɔlv fɔ sɔm tɛm. Bikɔs if pɔsin kɔntinyu fɔ gi am blɔd, i kin mek ayɔn bɔku na di bɔdi, dɛn nid fɔ gɛt sɛpret tritmɛnt (Chelation Therapy) fɔ pul di ayɔn we pasmak.
- Ɔpreshɔn: If di tin we mek di sik na taymus gland tumor (Thymoma), dɛn kin du ɔpreshɔn fɔ pul di gland (Thymectomy).
- Stem Sεl Transplant: Insay sכm jεnεtik kכndishכn dεm, dεn kin transplant stεm sεl dεm we dεn tek frכm hεlty pכsin fכ tray fכ mek nyu hεlty bon mכro sistεm.
- Immunoglobulin Therapy: If PRCA na Parvovirus B19 infɛkshɔn, dis tritmɛnt de kɔntrol di vayrɔs.
Lɛ wi lan bak bɔt di bad tin dɛn we di tritmɛnt dɛn kin du.
Lɛk ɔl di tritmɛnt dɛm, PRCA tritmɛnt kin mek sɔm sayd ɛfɛkt dɛm. Bɔt yu dɔktɔ go ɛksplen ɔl dis to yu bifo tɛm.
Sayd ɛfɛkt dɛn we di mɛrɛsin dɛn we de mek di bɔdi nɔ gɛt bɛtɛ wɛlbɔdi kin gɛt
- Akni we gɛt akni
- Risk fɔ gɛt dayabitis
- Ay Blɔd Prɛshɔn
- Ɔstioporosis we pɔsin kin gɛt
- We yu de gɛt mɔ wet
- Bɛlɛ de at ɛn nɔs
Di bad tin dɛn we kin apin we pɔsin transfyuz blɔd
- Fiva ɛn alɛji (it) .
- Risk fɔ gɛt di sik
- Ayɔn ɔvalod
Dɛn sayd ɛfɛkt ya nɔ kin apin to ɔlman, ɛn yu dɔktɔ go ɛp yu fɔ kɔntrol dɛn. So nid nɔ de fɔ wɔri.
Aw i tan lɛk fɔ liv wit PRCA ɛn aw a kin tek kia ɔf misɛf?
Sɔntɛnde, PRCA kin bi wan sik we nɔ de mɛn. Di sik kin ɔl tu dɔn afta dɛn dɔn trit am ɔ i kin kam bak. So, bɔrku tin de wae yu fɔ tink bɔt wae yu de liv wit dis sik.
- Si yu dɔktɔ ɔltɛm: Ilɛksɛf yu sik nɔ de igen afta yu dɔn trit yu, mek shɔ se yu go chɛk-ap di tɛm we yu dɔktɔ tɛl yu fɔ du. Dis go ɛp yu fɔ no ɛni risk fɔ mek di sik kam bak kwik kwik wan.
- Di doz fɔ mɛntenans: Sɔm pipul dɛn kin nid fɔ kɔntinyu fɔ tek mɛrɛsin we dɛn nɔ de tek fɔ mek di sik nɔ kam bak.
- Fɔ liv fayn layf:
- Gud it: Aks yu dɔktɔ bɔt it dɛn we gɛt aynɔ ɛn it we gɛt fayn fayn tin dɛn fɔ it.
- Drink inof wata: Mek di bɔdi nɔ gɛt wata.
- Ɛksesaiz: Du ɛksesaiz we sef we fayn fɔ yu, lɛk aw yu dɔktɔ advays yu.
- Protɛkt yusɛf frɔm infɛkshɔn:Wash yu an ɔltɛm. Tek tɛm na say dɛn we pipul dɛn kin bɔku. Tɔk to yu dɔktɔ bɔt ɛni vaysin we yu nid.
- Pe atɛnshɔn to yu sik dɛn: If yu notis ɛni chenj na yu bɔdi ɔ ɛni nyu sayn, tɛl yu dɔktɔ.
Mɛsej we dɛn kin kɛr go na os
- Pure Red Cell Aplasia (PRCA) na wan sik we nɔ kin apin so ɔltɛm bɔt we kin mek di bon mɛrɔ stɔp fɔ mek rɛd blɔd sɛl.
- De men prɔblɛm wae kin kam wit dis na wae pɔrsin kin gɛt siriɔs anemia. Di men sayn dɛm na wae yu taya pasmak, yu kin gɛt blɛsin, ɛn yu nɔ kin ebul fɔ blo.
- Bɔrku rizin de fɔ dis, wit prɔblɛm wit di imyun sistɛm, kansa, ɛn vayral infɛkshɔn na di men wan dɛm.
- Blɔd tɛst ɛn bon mɛro ɛgzamin impɔtant fɔ mek dɛn no di sik kɔrɛkt wan.
- Tritmεnt dεm de wae de woke fayn fayn wan dipεnd pan de tin wae de mek yu sik. Bɔt as di sik kin kam bak, i rili impɔtant fɔ fala yu dɔktɔ in instrɔkshɔn.
- If yu ɔr pɔrsin wae yu sabi gɛt dis sik, nɔr panik ɛn go to dɔktɔ kwik kwik wan.
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