Yu de gɛt bad bad sik dɛn na yu skin wantɛm wantɛm? Mek wi lan bɔt Pyoderma Gangrenosum!

Yu dɔn ɛva gɛt smɔl blista ɔ rɛd ples na yu skin we bigin lɛk smɔl blista ɔ rɛd ples ɛn wantɛm wantɛm i tɔn to big ɔlsa we de mek yu fil pen? I kin apin na pas wan ples, bɔt i kin apin bak na bɔku say dɛn na yu bɔdi. Dis na rili wan kɔndishɔn wae nid sɔm atɛnshɔn ɛn kin kɔmplikt smɔl. Tide wi go tɔk bɔt wan sik we de na di skin we dɛn kɔl Pyoderma Gangrenosum, we na wan sik we nɔ kin bɔku bɔt we rili impɔtant fɔ no bɔt. Nɔ wɔri, lɛ wi kip am simpul.

Wetin na dis Pyoderma Gangrenosum?

Fɔ tɔk am simpul wan, pyoderma gangrenosum na wan sik we nɔ de mɛn , we min se i de te fɔ lɔng tɛm, ɛn we de kam bak na di skin. Wetin kin apin na dat yu skin kin bigin fɔ gɛt smɔl smɔl blista dɛn we nɔ gɛt kɔlɔ (sɔntɛm rɛd, pepul, blu, brawn, ɔ blak) ɔ blista dɛn we ful-ɔp wit wata (bullae). Wetin denja pas ɔl na dat dɛn tin ya kin gro kwik kwik wan, jɔyn togɛda, ɛn bi dip, opin sɔri (ɔlsa) .

Imajin aw i go tan lɛk if sɔntin bigin lɛk smɔl pimpl ɛn insay sɔm dez i tɔn to ɔlsa we de mek pɔsin fil pen we di sayz lɛk nikɛl? Na dat de apin na ya. Sɔm pipul dɛn kin jɔs gɛt wan ɔlsa, bɔt if i siriɔs, bɔku ɔlsa kin kam wan tɛm. Dɛn ɔlsa ya kin mek pɔsin fil pen bad bad wan .

Impɔtant, pyoderma gangrenosum kin gɛt fɔ du wit ɔda sik dɛn we de na di sistɛm , we min se i nɔ jɔs bi prɔblɛm na di skin.

Udat go mɔs gɛt dis?

Pyoderma gangrenosum kin apin pan ɛni ej, bɔt i nɔ kin apin so ɔltɛm pan pikin dɛn . I kin mɔs pan uman dɛn we ol bitwin 20 ɛn 50. Yu kin gɛt pyoderma gangrenosum bak if yu gɛt ɛni wan pan dɛn sik ya:

• Rumatoid arthritis - Dis na sik wae de mek di joyn dεm inflameshn.
• Ulcerative colitis - Na inflammatory kondishɔn wit ɔlsa na di big intestin.
• Krohn sik - na כda inflammatory kכndyushכn we de apin na di dijestiv trakt.
• Sɔm kayn kansa, fɔ ɛgzampul, blɔd kansa lɛk lukimiya ɔ limfoma.

Dɛn se i kin apin to lɛk wan pan ɛvri ɔndrɛd tawzin pipul dɛn na Amɛrika . Dat min se i nɔ kɔmɔn so.

Aw dis kin afɛkt di bɔdi? Wetin na di sayn dɛm we de sho se yu gɛt dis sik?

Pyoderma gangrenosum de mek yu skin gɛt smɔl smɔl blista dɛn we nɔ gɛt kɔlɔ ɛn inflamɛns, we min se yu de swel ɛn rɛd. Dɛn blista ya kin apia ɛnisay na di bɔdi, bɔt dɛn kin si dɛn mɔ na di leg, anklɛ, ɛn fut (di ɔda pat dɛn we de dɔŋ) .

Dɛn blista ya kin bɔs kwik kwik wan, tɔn to big ɔlsa we kin mek pɔsin fil pen, ɛn i kin skata.Di men sayn dɛm wae de sho se yu gɛt dis sik na:

• Smɔl smɔl blista dɛn we ful-ɔp wit pus (rɛd, pepul, blu, brawn, ɔ blak). Dɛn tin ya kin big kwik kwik wan .
• Open sores (ulcers) de divεlכp. di ed dεm we de rawnd dεn sor dεm ya de rayz εn dεn kin si am klia wan .
• Swel ɛn bad bad pen rawnd di wund.
• Sɔm pipul dɛn kin gɛt fiva .
• Jɔyn pen kin apin bak.

Sɔntɛnde, dɛn wund ya kin rili big ɛn dip , ɛn di pen nɔ kin bia.

Sɔm stɔdi dɔn sho se te to 70% pan di pipul dɛm wae gɛt pyoderma gangrenosum kin gɛt mɔr pas wan ɔda kɔndishɔn (comorbidities) di sem tɛm. we dεn kכmbayn pyoderma gangrenosum wit כda kכndyushכn dεm, dεn kin se di risk fכ day kin inkrεs te to 30%. So, dis nɔto sɔntin we wi fɔ tek am layt.

Dis na sik we pɔsin kin gɛt we i de fɛt insɛf?

Yɛs, dɛn biliv se pyoderma gangrenosum na sik we pɔsin kin gɛt we i de fɛt insɛf . Fɔ tɔk am simpul wan, yu bɔdi in yon difens sistɛm, we na di imyun sistɛm, de atak yu yon skin sɛl dɛn. Fɔ sɔm pipul dɛm, di pyoderma gangrenosum kin sɔlv we dɛn trit di ɔda tin dɛm wae wi bin dɔn tɔk bɔt.

Wetin mek di pyoderma gangrenosum de divɛlɔp?

Di wan dɛn we sabi bɔt mɛrɛsin stil nɔ no di rayt tin we kin mek dɛn gɛt dis sik , bɔt pas af pan di pipul dɛn we gɛt pyoderma gangrenosum gɛt ɔda sik dɛn (lɛk at at sik, lukimiya, ɛn Crohn’s disease), lɛk aw wi bin dɔn tɔk.

pan tap dat, pyoderma gangrenosum kin apin bak afta yu skin injuri, abrashכn, כ כpεrayshכn (pathergy) . Imajin wan smɔl abrashɔn na yu an, ɔ smɔl ɔpreshɔn, ɛn na dis say dis sik kin bigin. Sɔntɛnde dɛn wund ya kin divɛlɔp bak rawnd wan say we di stoma de afta dɛn dɔn ɔpreshɔn. dεn kכl dis pεristכmal payoderma gangrenosum.

Yu tink se dis kin pas?

Nɔ, Pyoderma gangrenosum nɔ kin gɛt di sik . I nɔ kin ebul fɔ pas frɔm wan pɔsin to ɔda pɔsin tru di skin to di skin we i tɔch. Dis na tin we bɔku pipul dɛn kin wɔri bɔt, so i impɔtant fɔ mek wi no klia wan bɔt dis.

Aw dɔktɔ dɛn kin no dis?

Fɔ tɔk tru, fɔ no if pɔsin gɛt pyoderma gangrenosum kin tranga smɔl . Nɔr difinitiv tɛst nɔr de wae go kɔnfirm se na di kɔndishɔn. So, bɔku tɛm, dɔktɔ dɛn kin du tɛst fɔ no ɔda tin dɛn we kin mek pɔsin gɛt di sem kayn prɔblɛm dɛn na di skin. Dat min se, dɛn kin mek shɔ fɔs se ɔda sik dɛn we gɛt di sem kayn sayn nɔ de. Fɔ ɛgzampul:

• Difrɛn infɛkshɔn dɛn.
• Kansa dɛn na di skin.
• Blɔd vesel dɛn we de inflamɛns na di skin.
• Lupus sik we dɛn kɔl Lupus sik.
• Wan sik we dɛn kɔl Swit sindrom.

Test fɔ dis kin inklud:

• Blɔd tɛst dɛn.
• Fɔ tek smɔl pat pan di skin fɔ ɛgzamin (Bayopsy).
• Bon mכro sεmpl - εspεshali if dεn sכspεkt tin dεm lεk blכd kεnsar.
• Prɔktoskɔpi we dɛn kin du.
• Kolonoskopi - if dεn sכspεkt kכndyushכn lεk Crohn in sik.

Na afta dɛn dɔn du ɔl dɛn tɛst ya ɛn dɛn dɔn pul ɔl ɔda tin dɛn, na in di dɔktɔ kin kam fɔ no se na pyoderma gangrenosum.

Wetin na di tritmɛnt dɛn?

Bɔku tritmɛnt opshɔn dɛn de fɔ pyoderma gangrenosum. Fɔ no di sik kwik kwik wan ɛn fɔ trit am impɔtant fɔ mek yu nɔ gɛt skata .

Tritmɛnt fɔ kɔmɔn, nɔr siriɔs kes dɛm

If di wund dɛn nɔ tu bad, di dɔktɔ kin gi yu krim ɔ ɔntmɛnt we yu kin put pan yu bɔdi. Dɛn tin ya na:

• Kɔtikosterɔyd: Dɛn mɛrɛsin ya we de ridyus di inflamɛns. Yu kin put dɛn pan wund as krim ɔ tek dɛn as pils. Ɛgzampul dɛn: kɔtizɔn, prɛdnizɔn. Bɔt dɛn tin ya kin gɛt sayd ɛfɛkt lɛk we pɔsin want fɔ it mɔ, we i de gɛt bɔku bɔku wet, we i de fil chenj, we i de gɛt akni, ɛn we i nɔ de slip.
• Nɔn-steroidal anti-inflammatory drugs (NSAID): Dɛn tin ya na tin dɛn we de mek pɔsin nɔ fil pen. Ɛgzampul dɛn: aspirin, ibuprofen. Dɛn tin ya kin mek yu gɛt gas , blo, yu bɛlɛ kin at, yu nɔs, yu kin vɔmit, yu kin gɛt dayarɛa, ɛn yu kin gɛt kɔnstipɛshɔn.
• Silva sulfadiazine skin cream: Dis na rili antibayɔtik krim we dɛn kin put pan pɔsin we bɔn fɔ mek i nɔ gɛt di sik. Sɔmtɛm dɛn kin yuse am fɔ dis sik bak. I kin mek yu it, fiva, kol, yu skin kin gɛt lɛsin, ɛn yu kin fil lɛk di san we de shayn.

Wan harsh smɔl?

If di injuri bad pasmak, di dɔktɔ kin gi yu tritmɛnt dɛn lɛk dɛn wan ya:

• Immunosuppressant medications: Dɛn wan ya de wok bay we dɛn de ridyus di ebul we yu imyun sistɛm nɔ ebul fɔ pwɛl in yon bɔdi. Ɛgzampul dɛn: maykofɛnɔlayt, sayklɔspɔrin.
• Bayolojikal ejen: Dis na nyu kayn drɔgs. Dɛn de wok bay we dɛn de tɔch sɔm patikyula prɔtin dɛn na di bɔdi we de mek pɔsin inflamɛns. Ɛgzampul dɛn: infliximab, adalimumab, ustekinumab.
• haypabarik כksijεn tεrapi: Dis involv fכ gi 100% כksijεn insay wan spεshal chεmba. Dɛn se i kin mek di bɔdi tisu dɛn wɛl kwik kwik wan.

Lɛ wi lan bak bɔt ɔpreshɔn.

Sɔntɛnde, we dɛn du ɔpreshɔn fɔ pul di day tisu na di wund (debriding) kin ɛp. Bɔt dis gɛt prɔblɛm dɛn bak .Bikɔs di skin we de pwɛl (pathergy) kin mek di sayn dɛm fɔ pyoderma gangrenosum wɔs, yu fɔ tek tɛm du dis ɛn yu fɔ du am bay wetin yu dɔktɔ disayd.

Sɔntɛnde, dɛn kin du wan skin graft . Dis min se dɛn kin tek di skin frɔm wan pat na di bɔdi we gɛt wɛlbɔdi ɛn transplant am na di say we di wund de.

Wetin yu nid fɔ no as pɔrsin wae gɛt dis sik?

If yu gɛt pyoderma gangrenosum, ɛni kayn trauma na yu skin – kɔt, skrap, brus – kin mek yu simptom dɛn wɔs . So yu nid fɔ tek tɛm as yu ebul. Imajin se yu de wok na gadin ɔ na kichin, ɛn ivin smɔl skrach kin bi big prɔblɛm.

Dɔn bak, fɔ kip wund dɛn klin impɔtant fɔ mek yu nɔ gɛt di sik .

• Wash di wund dɛn fayn fayn wan wit klin wata we de rɔn ɛn sop.
• Dɔn, tek tɛm kɔba di wund wit bandej we nɔ de adhesive. Dis go mek dɔti ɛn jem nɔ go insay.
• Yu dɔktɔ we de mɛn yu skin go gi yu mɔ infɔmeshɔn bɔt aw fɔ kip di wund klin ɛn aw fɔ put bandej. Tek tɛm fala dɛn instrɔkshɔn dɛn de.
• If dɛn dɔn gi yu ɔnt, was di wund, put di ɔnt, dɔn bandej am.

Fɔ bad bad wund, yu dɔktɔ kin tɛl yu fɔ yuz haydrokɔlɔyd bandej . Dɛn tin ya de protɛkt di wund fɔ mek i nɔ rɔb am mɔ ɛn mek i nɔ gɛt infɛkshɔn. Dɛn go "mɛlt" insay di skin insay tu to tri dez.

Aw lɔng i kin tek fɔ mek i wɛl?

Pyoderma gangrenosum na wan sik we at fɔ trit . Ivin if dɛn trit di wund dɛn fayn, i kin tek sɔm wiks, sɔm tɛm dɛn kin tek sɔm mɔnt fɔ mek dɛn wɛl. So, yu nid fɔ peshɛnt.

Yu tink se dɛn go ebul fɔ stɔp dis?

Bikɔs wi nɔ no di rayt tin we kin mek i apin, i nɔ kin izi fɔ tɔk fɔ tru aw fɔ mek i nɔ apin . Bɔt if yu gɛt tin dɛn we kin mek yu gɛt prɔblɛm lɛk lukimia ɔ inflammatory bowel disease, ɛn yu gɛt ɛni nyu prɔblɛm wit yu skin (especially sores we de gro kwik) , tɛl yu dɔktɔ wantɛm wantɛm . Aks yu dɔktɔ fɔ rifer yu to dɔktɔ we de mɛn yu skin ɔ ɔda spɛshal dɔktɔ we gɛt ɛkspiriɛns wit pyoderma gangrenosum.

Ustɛm a fɔ go to dɔktɔ?

Yu fɔ rili go to dɔktɔ pan dɛn kayn tin ya:

• If yu gɛt inflammatory bowel disease, arthritis, ɔ blɔd disɔda ɛn yu gɛt blista ɔ sore we kin big kwik kwik wan .
• If yu wund luk lɛk se i gɛt di sik (rɛd, pepul, grey ɔ wayt, i dɔn swel, ɔ i de pen).
• If yu gɛt nyu sayn dɛn .
• If yu gɛt siriɔs sayd ɛfɛkt afta yu dɔn tek di mɛrɛsin.

Impɔtant kwɛstyɔn dɛn fɔ aks yu dɔktɔ

We yu go si dɔktɔ, i rili impɔtant fɔ aks dɛn kwɛstyɔn ya:

• Aw ɛksaktɔli yu se a gɛt pyoderma gangrenosum?
• If a nɔ gɛt pyoderma gangrenosum, us ɔda sik na di skin i kin bi?
• Us kayn tɛst yu de op fɔ du?
• Us kayn mɛrɛsin ɔ tritmɛnt yu kin advays?
• Yu kin gi mi sɔm krim fɔ put am ɔ sɔm mɛrɛsin fɔ drink?
• Wetin na di ful list fɔ di sayd ɛfɛkt dɛm fɔ dɛn mɛrɛsin ɛn tritmɛnt dɛm ya?
• Wetin bak a fɔ du fɔ mek a nɔ gɛt bɔku sik?
• A fɔ go to dɔktɔ we de mɛn pipul dɛn we gɛt bɔdi, plastic sajin, gastroenterologist, immunologist, ɔ ɔda spɛshal pɔsin?

I rili impɔtant fɔ aks dɛn kwɛstyɔn ya ɛn ɔndastand di tin we de apin to yu klia wan.

Wetin na di difrɛns bitwin Pyoderma Gangrenosum ɛn Ecthyma Gangrenosum?

Dɛn tu nem ya fiba smɔl, so wi kin kɔnfyus.

Ecthyma gangrenosum na wan sik we nɔ kin apin na di skin we nɔ kin apin so ɔltɛm we Pseudomonas bacteraemia, we na wan baktri we dɛn kin si na wata ɛn grɔn. I kin mek bak di skin gɛt lɛsin ɛn nɛkrɔsis pan di tisu dɛn we de rawnd am. I kin afɛkt pipul dɛn we gɛt wikɛd imyun sistɛm .

Pyoderma gangrenosum kin mek bak di skin gɛt lɛsin. Wi nɔ no di rayt tin we mek i apin. Dɛn kin tink se na wan sik we de mek pɔsin nɔ ebul fɔ fɛt insɛf. Bɔt nɔto di fɔs tin we kin afɛkt pipul dɛn we gɛt wikɛd imyun sistɛm .

difrεn kayn pyoderma gangrenosum lεsin dεm de?

Yes, fכ men kayn pyoderma gangrenosum lεsin dεm de:

• Klasik pyoderma gangrenosum: Dis na di kayn we we dɛn kin yuz mɔ. Sɔm dɛn we de mek pɔsin fil pen kin kam na di leg dɛn.
• Atypical ɔ bullous pyoderma gangrenosum: Dis kayn kin apin lɛk blista we ful-ɔp wit wata. Bɔku tɛm, dɛn kin si am na di an dɛn. E kin bɔrku pan pipul dɛm wae gɛt lukimiya.
• Pustular pyoderma gangrenosum: I kin tan lɛk smɔl smɔl blista dɛn we ful-ɔp wit pus (pustules) na di an ɛn fut. Dis kin apin mɔ pan pipul dɛm wae gɛt inflammatory bowel disease.
• Vegetative pyoderma gangrenosum: Dis kayn lɛsin nɔ kin fil pen.

Fɔ dɔn, tin dɛn we wi fɔ mɛmba

Pyoderma gangrenosum na wan sik we de stat as smɔl smɔl blista na di skin ɛn i kin tɔn kwik kwik wan to big big lɛsin. I kin tranga fɔ no ɛn trit am , so yu ɛn yu dɔktɔ nid fɔ peshɛnt.

Mɛmba se, i rili impɔtant fɔ tek tɛm wit ɛni trauma we de na yu skin, bikɔs dis kin mek yu gɛt nyu lɛsin dɛn.

If pyoderma gangrenosum tranga ɛn yu gɛt ɔda kɔmɔn sik dɛn, i kin mek yu fil bad bad wan, yu gɛt skata, ɛn ivin gɛt prɔblɛm dɛn we kin mek yu layf de pan denja. So, if yu gɛt ɔtoimyun sik ɛn yu de gɛt sɔm sik dɛn na yu skin we de gro kwik kwik wan, go to dɔktɔ wantɛm wantɛm. If yu no am kwik kwik wan ɛn trit yu, dat kin ɛp yu fɔ wɛl. Nɔ panik , bɔt tek tɛm.

` Pyoderma Gangrenosum, Skin Disizin, Wund, Ɔlsa, Imyun Sistɛm, Dɛmatɔlɔji, Kronik Disizin