Yu ɔ pɔsin we yu sabi go mɔs de gɛt kansa tritmɛnt. We dɛn de du dis tritmɛnt, mɔ di kemotɛrapi, di kansa sɛl dɛn kin pwɛl kwik kwik wan. Pan ɔl we dis na gud tin, we dɛn sɛl dɛn ya dɔn pwɛl, di tin dɛn we de insay dɛn, mɔ wan kemikal we dɛn kɔl yurik asid , kin gɛda bɔku bɔku wan na di blɔd. Dis we aw yurik asid de bɔku wantɛm wantɛm nɔ fayn fɔ wi kidni dɛn. So, na dis kayn tin, dɔktɔ dɛn kin yuz wan spɛshal mɛrɛsin we dɛn kɔl `Rasburicase`. Tide, lɛ wi tɔk bɔt dis drɔg insay simpul wɔd dɛn.
Wetin na dis Rasburicase? Wetin i rili de du?
Fɔ tɔk am simpul wan, Rasburicase (ರಾಸ್-ಬೀರೀ-ಕ್ಸ್) na wan mɛrɛsin we de kɔntrol di kayn yurik asid we de na wi blɔd. Dɛn kin yuz am mɔ fɔ ridyus ɛn mek di yurik asid lɛvɛl we de na di bɔdi go ɔp wantɛm wantɛm bikɔs ɔf di tritmɛnt fɔ kansa.
Tink bɔt wi blɔd vesel dɛn lɛk rod. We di kansa sɛl dɛn dɔn pwɛl, yurik asid kin mek bɔku trafik de na dis rod. Dis trafik kin ambɔg di wok we di ɔgan we impɔtant pas ɔl, we na di kidni dɛn, de wok. Di drɔg `Rasburicase` de wok lɛk trafik polisman, i de pul dis trafik jam we gɛt yurik asid ɛn chenj am to ɔda kemikal we kin kɔmɔt na di bɔdi izi wan. Dis kin mek dɛn kɔntinyu fɔ gɛt kansa tritmɛnt we nɔ go ambɔg di kidni dɛn.
Dis mɛrɛsin kin kam lɛk wata (infusion) we dɛn kin gi insay wan vein. Dat min se dɛn kin gi am na di bɔdi smɔl smɔl, lɛk salin. Dɛn kin gi am na ɔspitul ɔ klinik ɔnda di sɔpɔtishɔn fɔ dɔktɔ ɛn nɔs wokman dɛn. `Elitek` na wan brand nem we pipul sabi fɔ dis mɛrɛsin.
Tin dɛm we yu fɔ rili tɛl yu dɔktɔ bifo yu tek dis mɛrɛsin
Rasburicase na wan mɛrɛsin we rili pawaful. So, i rili impɔtant fɔ tɛl yu dɔktɔ bɔt yu kɔmplit wɛlbɔdi histri bifo yu bigin fɔ trit yu. I impɔtant mɔ fɔ tɛl dɛn if yu gɛt ɛni wan pan dɛn tin ya:
| Wɛlbɔdi kɔndishɔn ɔ istri | Wetin mek i impɔtant? (Simpul ɛksplen) |
|---|---|
| G6PD dɛfisiɛns | Dis na jεnεtik kכndyushכn we involv wan εnzym insay blכd sεl dεm. If dɛn gi pipul dɛn we gɛt dis sik Rasburicase, di rɛd blɔd sɛl dɛn kin brok ɛn mek dɛn gɛt siriɔs anemia. So dis rili impɔtant. |
| Anemia ɔ istri bɔt aw dɛn dɔn gi blɔd | If yu dɔn gɛt anemia ɔ yu dɔn transfyushɔn blɔd bifo, i impɔtant fɔ tɛl yu dɔktɔ. |
| Difrɛn alɛji dɛn (Alɛji) . | Mek shɔ se yu tɛl yu dɔktɔ if yu gɛt ɛni alɛji to rasburicase, yist, manitol, ɔda mɛrɛsin, it, ɔ day. |
| Bɛlɛ ɔ tray fɔ gɛt bɛlɛ | If yu gɛt bɛlɛ ɔ yu de plan fɔ gɛt bɛlɛ, i rili impɔtant fɔ tɛl yu dɔktɔ. |
| Fɔ gi pikin in mama in bɛlɛ | Yu fɔ avɔyd fɔ gi pikin in bɛlɛ we yu de tek dis mɛrɛsin ɛn fɔ 2 wik afta yu dɔn stɔp am. So if yu na mama we de gi pikin in bɛlɛ, tɛl yu dɔktɔ bɔt am bak. |
Tin dɛn we yu fɔ tek tɛm wit we yu de yuz dis mɛrɛsin
Di mɛdikal wokman dɛm go wach yu gud gud wan we dɛn de gi yu dis mɛrɛsin.
- Blɔd tɛst: We yu de du tritmɛnt, yu go nid fɔ du blɔd tɛst ɔltɛm fɔ chɛk yu yurik asid lɛvɛl, aw di mɛrɛsin de wok fayn, ɛn if ɛni bad bad tin de apin. Dis na nɔmal tin, so nɔ wɔri.
- Ɔda mɛrɛsin dɛn: Gi yu dɔktɔ wan kɔmplit list fɔ ɛni ɔda mɛrɛsin, vaytamɛn, ɛbul mɛrɛsin, ɛn sɔpɔtmɛnt dɛn we yu de tek. Sɔm kin intarakt wit dis mɛrɛsin.
- Fɔ pikin dɛn: Sɔntɛnde dɛn kin gi dis mɛrɛsin to pikin dɛn we yɔŋ lɛk 1 mɔnt. Bɔt dɛn fɔ fala spɛshal tin dɛn fɔ tek tɛm wit. If yu de gi yu pikin dis mɛrɛsin, tɔk to yu dɔktɔ we de mɛn pikin dɛn bɔt am.
Bikɔs dɛn kin gi dis mɛrɛsin na ɔspitul we dɔktɔ ɛn nɔs dɛn de wach yu dairekt wan, yu nɔ nid fɔ wɔri bɔt if yu tek am pasmak. If yu fil ɛni prɔblɛm pan ɛni we, tɛl di nɔs ɔ dɔktɔ wantɛm wantɛm. Dɛn go tek di step dɛn we nid fɔ du dat. If yu saspek ɛni ɔda pɔyzin, yu kin kɔl di Nashɔnal Pɔyzin Infɔmeshɔn Sɛnta na di Kɔlɔmbɔ Nashɔnal Ospital fɔ advays.
Wetin na di poshubul sayd effekt dɛm fɔ Rasburicase?
Lɛk ɛni mɛrɛsin, `Rasburicase` kin mek sɔm pipul dɛn gɛt sayd ɛfɛkt. Bɔt, nɔto ɔlman kin gɛt dɛn. De tin wae impɔtant pas ɔl na fɔ ripɔt ɛni sayn kwik kwik wan.
| Klasifikɛshɔn fɔ di sayd ɛfɛkt dɛn | |
|---|---|
| Siriɔs sayd ɛfɛkt dɛm we yu fɔ ripɔt to yu dɔktɔ ɔ nɔs wantɛm wantɛm | |
| Alɛji we pɔsin kin gɛt | Skin rash, it, swel na di fes, lip ɔ tong. |
| I nɔ izi fɔ blo | I nɔ izi fɔ blo, yu chɛst de pen ɔ yu tayt. |
| Prɔblɛm dɛn we kin apin to di blɔd we de kɔmɔt na di blɔd | Blu lip ɔ finga nel, at bit fast ɔ i nɔ de bit ɔltɛm, fɔdɔm, blɔd prɛshɔn we de dɔŋ, yu yay ɔ yu skin de yɔlɔ. |
| Ɔda siriɔs sayn dɛn | Siz, taya pasmak ɔ taya, kɔnfyushɔn. |
| Sayd ɛfɛkt dɛn we nɔ kin siriɔs, bɔt dɛn fɔ ripɔt to di dɔktɔ if dɛn kɔntinyu fɔ de | |
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Dis list nɔr gɛt ɔl di sayd ɛfɛkt dɛm we yu kin gɛt, so if yu gɛt ɛnitin we nɔ kɔmɔn, nɔ fred fɔ tɔk to yu dɔktɔ bɔt am.
Mɛsej we dɛn kin kɛr go na os
- `Rasburicase` na spɛshal mɛrɛsin we dɛn kin gi na ɔspitul fɔ ridyus di yurik asid we de na di blɔd we kin bɔku bikɔs ɔf kansa tritmɛnt.
- Bifo yu bigin fɔ trit yu, mek shɔ se yu tɛl yu dɔktɔ bɔt yu G6PD dɛfisiɛns, alɛji, ɛn ɔl ɔda mɛrɛsin sik dɛn.
- I impɔtant fɔ du blɔd tɛst ɔltɛm we dɛn de du di tritmɛnt.
- Notis yu dɔktɔ ɔ nɔs wantɛm wantɛm if yu gɛt ɛni bad bad alɛji, lɛk we i nɔ izi fɔ blo, we yu skin de rɔsh, ɔ yu fes de swel.
- Nɔ gi pikin in bɛlɛ ɔltogɛda we yu de tek dis mɛrɛsin ɛn fɔ 2 wik afta yu dɔn stɔp.
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