Yu dɔktɔ dɔn gi yu Selumetinib fɔ yu ɔ yu pikin? a no se yu geht bohku kweshon boht am bikohs na bit na speshal mɛrɛsin. Dat na nɔmal tin. Nɔ wɔri, wi go tɔk simpul ɛn klia wan bɔt dis mɛrɛsin, aw dɛn de yuz am, di sayd ɛfɛkt dɛn we pɔsin kin gɛt, ɛn tin dɛn we wi fɔ tek tɛm mɔ bɔt.
Us kayn mɛrɛsin dis? Wetin rili i de du?
Fɔ tɔk am simpul wan, Selumetinib na wan mɛrɛsin we dɛn kin yuz fɔ mɛn wan sik we dɛn kɔl nyurofibromatosis . Dis kכndyushכn de mek di tכmכro dεm de gro along di nεv dεm na wi bכdi. So wetin dis drɔg de du na fɔ blok wan patikyula prɔtin we de ɛp dɛn tumbu sɛl dɛn de fɔ gro, sheb, ɛn bɔku. Fɔ tɔk mɔ, i de kɔntrol di rit we di tɔŋ dɛn de gro.
Yu kin bay dis mɛrɛsin na di famasi ɔnda di brand nem Koselugo . Sɔntɛnde, dɔktɔ dɛn kin gi dis mɛrɛsin bak fɔ ɔda sik dɛn we pɔsin kin gɛt.
Tin dɛm wae yu fɔ tɛl yu dɔktɔ bifo yu bigin fɔ tek mɛrɛsin
Bifo yu bigin dis mɛrɛsin, i impɔtant fɔ gi yu dɔktɔ wan kɔmplit pikchɔ bɔt yu wɛlbɔdi prɔblɛm. Dis rili impɔtant fɔ mek yu sef. If yu gɛt ɛni wan pan dɛn tin ya, mek shɔ se yu tɛl dɛn bɔt dɛn.
| Wetin yu nid fɔ no | Wetin mek dat impɔtant? |
|---|---|
| Dizayd we de mek pɔsin blɔd de kɔmɔt | Dis mɛrɛsin kin mek yu gɛt mɔ blɔd, so if yu dɔn gɛt prɔblɛm lɛk dat, yu dɔktɔ fɔ no bɔt am. |
| Ay sik ɔr prɔblɛm wit yu yay | Selumetinib kin afɛkt di we aw yu de si, so i impɔtant fɔ tɛl yu dɔktɔ bɔt ɛni prɔblɛm we bin dɔn de bifo. |
| At sik | Sɔntɛnde dis mɛrɛsin kin afɛkt di we aw di at de wok. |
| Liva sik | Di liva na di say we dɛn kin pul di mɛrɛsin na di bɔdi. If yu gɛt prɔblɛm wit yu liva, yu go nid fɔ chenj di doz we yu de gi yu. |
| Alɛji to selumetinib ɔ ɛni ɔda tin we dɛn kin yuz fɔ mek am | Mek shɔ se yu tɛl wi if yu gɛt ɛni alɛji fɔ dis mɛrɛsin, ɔda mɛrɛsin, it, ɔ day. |
| If yu ɔ yu patna de tray fɔ gɛt bɛlɛ ɔ yu gɛt bɛlɛ. | Dis rili impɔtant. Dis mɛrɛsin kin ambɔg di pikin we de na di bɛlɛ. Wi go tɔk mɔ bɔt dis. |
| If yu na mama we de gi pikin in bɛlɛ. | Tɛl di dɔktɔ bak bɔt aw fɔ gi pikin in mama in bɛlɛ, bikɔs di mɛrɛsin kin pas to di pikin tru in mama in milk. |
Aw ɛksaktɔli a kin yuz dis mɛrɛsin?
Fɔ mek yu gɛt di bɛst pan di mɛrɛsin, i rili impɔtant fɔ yuz am di rayt we.
- Dis na kapsul. Yu fɔ swɛla am ɔl wit wan glas wata.
- Nɔ ɛva brok, krɔs, ɔ chew dis kapsul. If yu du dat, dat kin chenj di we aw di mɛrɛsin de wok.
- Tray fɔ tek yu mɛrɛsin di sem tɛm ɛvride , lɛk aw yu dɔktɔ tɛl yu. Dis go ɛp fɔ mek di mɛrɛsin kɔntinyu fɔ de na yu bɔdi.
- Yu kin tek am wit it ɔ yu nɔ it am. Bɔt if yu bɛlɛ at ɔ yu nɔs, i go fayn fɔ mek yu tek di mɛrɛsin wit sɔm it.
- Kɔntinyu fɔ yuz dis tritmɛnt te yu dɔktɔ tɛl yu fɔ stɔp.
- Impɔtant: Nɔ tek dis mɛrɛsin wit grep jus. I kin gɛt ɛfɛkt we yu nɔ want pan di wok we di mɛrɛsin de du.
If yu gi pikin dɛn dis mɛrɛsin
Sɔntɛnde, dɔktɔ kin gi dis mɛrɛsin fɔ pikin dɛn we ol lɛk 2 ia fɔ spɛshal mɛrɛsin. Bɔt dɛn kin tek tɛm du am. If yu de gi pikin dis mɛrɛsin, fala di dɔktɔ in instrɔkshɔn dɛn di rayt we.
Wetin fɔ du if yu tek mɛrɛsin pasmak?
If yu gɛt ivin smɔl saspek se yu dɔn tek mɔ mɛrɛsin pas aw yu tink, nɔ west tɛm. Wantɛm wantɛm, kɔl di Nashɔnal Pɔyzin Infɔmeshɔn Sɛnta na di Kɔlɔmbɔ Nashɔnal Ospital, ɔ go na di Imejɛnsi Tritmɛnt Yunit (ETU) na di ɔspitul we de nia yu.
Dis na mɛrɛsin we dɛn rayt fɔ yu nɔmɔ. Nɔ ɛva tɛl ɔda pipul dɛn bɔt am, ilɛksɛf yu gɛt di sem kayn sik.
Wetin a go du if a fɔgɛt fɔ tek mi mɛrɛsin?
Ɔlman kin fɔgɛt tin. If dat apin, nɔ wɔri.
- If yu fɔgɛt fɔ tek yu pil ɛn i nɔ pas 6 awa pas di tɛm we yu kin tek am, tek am jɔs lɛk aw yu mɛmba.
- Bɔt if i let pas 6 awa , skip di doz we yu mis ɔltogɛda. Tek di nɛks doz di tɛm we yu kin tek am. Nɔ ɛva tek dɛbul doz fɔ mek di doz we yu dɔn fɔgɛt.
- If yu vɔmit afta yu tek di mɛrɛsin, skip da doz de. Nɔ tek am igen. Tek am lɛk aw yu kin tek am di nɛks tɛm.
Ɔda tin dɛm wae kin intarakt wit dis mɛrɛsin (Interactions) .
Sɔm mɛrɛsin, vaytamɛn, ɛn sɔpɔtmɛnt dɛn we yu de tek kin intarakt wit selumetinib. So, gi yu dɔktɔ wan kɔmplit list fɔ ɔltin we yu de tek - prɛskrishɔn mɛrɛsin, ɔva-di-kɔnta mɛrɛsin, ɛbul mɛrɛsin, ɛn vaytamɛn. Dɔn bak, tɛl yu dɔktɔ if yu de smok ɔ drink rɔm.
Fɔ ɛgzampul, dis mɛrɛsin kin miks wit dɛn tin ya:
- Aspirin ɛn ɔda kayn mɛrɛsin dɛn
- Sɔm antibayɔtiks, lɛk ɛrythromycin
- Sɔm antivayrɔs dɛn we dɛn kin gi fɔ HIV ɔ Epatitis
- Antifungals lɛk ketoconazole
- Antikonvulsant dɛm lɛk Phenobarbital ɛn Phenytoin
- Mɛrɛsin dɛn we de mek blɔd nɔ klot, lɛk Warfarin
- Vitamin E we gɛt di sik
Dis list nɔr kɔmplit, so i go fayn fɔ tɛl yu dɔktɔ bɔt ɔltin wae yu de tek.
Tin dɛn we yu fɔ tek tɛm wit mɔ we yu de tek mɛrɛsin
- Go fɔ chɛk-ap ɔltɛm: Yu dɔktɔ go tɛl yu fɔ kam insay fɔ chɛk-ap ɔltɛm. Nɔ mis dɛn de dɛn de. Na so dɛn kin chɛk if di mɛrɛsin de wok ɛn if ɛni prɔblɛm de.
- Risk fɔ blɔd: Dis mɛrɛsin kin mek yu gɛt mɔ blɔd frɔm ivin smɔl injury. Brus kin apin bak. If yu gɛt ɛni blɔd we nɔ kɔmɔn, lɛk blɔd na yu stɔl, vɔmit we tan lɛk kɔfi grɔn, ɔ rɛd ɔ pepul spat na yu bɔdi, tɛl yu dɔktɔ wantɛm wantɛm.
- Tek kia ɔf yu yay:Dɛn go chɛk yu yay bifo yu bigin fɔ tek dis mɛrɛsin ɛn we yu de tek am. If yu notis ɛni chenj na yu yay - lɛk we yu nɔ de si fayn, we yu si tin lɛk se dɛn de muv, ɔ si blak spat - tɛl yu dɔktɔ wantɛm wantɛm.
Spɛshal ɔwe bɔt bɛlɛ ɛn fɔ gi pikin in bɛlɛ
Dis pat rili impɔtant. Duya una pe atɛnshɔn gud wan.
- We yu gɛt bɛlɛ we yu de tek dis mɛrɛsin kin mek yu bɔn siriɔs prɔblɛm .
- So bifo yu bigin di mɛrɛsin, dɛn kin du bɛlɛ tɛst fɔ mek shɔ se yu nɔ gɛt bɛlɛ.
- Yu fɔ yuz wan we we rili wok fɔ mek yu nɔ bɔn pikin we yu de tek di pil ɛn fɔ wan wik afta yu dɔn stɔp di pil . Tɔk to yu dɔktɔ bɔt di we aw yu de du tin we fayn fɔ yu.
- If yu patna ebul fɔ gɛt bɛlɛ, i impɔtant fɔ yuz kɔndɔm we yu de du mami ɛn dadi biznɛs we yu de tek di pil ɛn fɔ wan wik afta yu dɔn stɔp.
- Dɔn bak, nɔ gi yu pikin in bɛlɛ we yu de tek dis mɛrɛsin ɛn fɔ wan wik afta yu dɔn stɔp.
Wetin na di bad tin dɛn we kin apin to pɔsin?
Lɛk ɛni mɛrɛsin, selumetinib kin mek yu gɛt sayd ɛfɛkt. Nɔto ɔlman kin gɛt dɛn, bɔt i impɔtant fɔ no bɔt dɛn.
| Sayd ɛfɛkt we pɔsin kin gɛt | Diskripshɔn ɛn wetin fɔ du |
|---|---|
| Sayd ɛfɛkt dɛm we yu fɔ ripɔt to yu dɔktɔ wantɛm wantɛm | |
| Alɛji we pɔsin kin gɛt | Skin rash, it, swel na di fes, lip, tong. |
| Blɔd we nɔ de kɔmɔt fayn | Blak ɔ blɔd stɔl, vɔmit we tan lɛk kɔfi grɔn, rɛd/dak brawn urine, rɛd/pɔpul spat na di skin. |
| Vishɔn kin chenj | Blɔr vishɔn, lɔs vishɔn, si tin lɛk se dɛn de drɛg, si blak spat. |
| Di sayn dɛm wae de sho se yu at nɔr de woke fayn | I nɔ izi fɔ blo, yu anklɛ, yu fut, yu an dɛn kin swel, yu bɔdi kin gɛt bɔku bɔku wet wantɛm wantɛm, yu kin taya pasmak. |
| Di sayn dɛn we de sho se pɔsin in liva wund | Pen na di ɔp rayt say na di bɛlɛ, yu nɔ de want fɔ it, yu nɔ de fil fayn, yu skin ɔ yu yay de yɔlɔ, yu urine dak. |
| Injury na di mɔsul dɛn | Taya we nɔ kɔmɔn, mɔsul dɛn de pen, dak yɔlɔ ɔ brawn urine. |
| Sivɛri dayarɛa ɔ bɛlɛ pen | Bɛlɛ pen ɔltɛm ɔ bad bad wan ɛn dayarɛa. |
| Sayd ɛfɛkt dɛn we nɔ kin siriɔs, bɔt dɛn fɔ ripɔt to di dɔktɔ if dɛn kɔntinyu fɔ de | |
| Kɔmɔn sayd ɛfɛkt dɛn | Bon, joyn ɔ mɔsul pen, dray skin, jenɛral diskɔmfɔt ɛn taya, ed pen, nɔs, bɛlɛ pen, vɔmit. |
Aw yu kin kip ɛn pul di mɛrɛsin?
- Kip sef: Kip am usay pikin ɛn animal dɛn we yu lɛk nɔ go ebul fɔ rich .
- Fɔ kip am: Stɔr am na rum tɛmpracha (20-25 digri sɛlshiɔs). Kip di mɛrɛsin we de insay di ɔrijinal bɔtul tayt tayt wan ɛn protɛkt am frɔm wet. Nɔ pul di smɔl paket (paket we de absɔb mɔstɔ) insay di bɔtul, bikɔs i de ɛp fɔ mek di mɛrɛsin dray.
- Di mɛrɛsin we dɔn pas: Nɔ yuz mɛrɛsin we dɔn pas.
- Fɔ pul am: .Dɛn fɔ trowe di mɛrɛsin dɛn we dɔn pas ɔ we dɛn nɔ nid igen fayn fayn wan. If yu nɔ shɔ if yu fɔ was dɛn dɔŋ di tɔylɛt ɔ trowe dɛn na dɔti, aks yu dɔktɔ. If yu de trowe dɛn na dɔti, pul di mɛrɛsin kɔmɔt na di bɔtul, miks am wit sɔntin lɛk ti lif we yu dɔn yuz, kɔfi grɔn, ɔ dɔti, put am na bag, sial am fayn fayn wan, ɛn trowe am na dɔti.
Mɛsej we dɛn kin kɛr go na os
- Ɔltɛm swɛla di Selumetinib kapsul dɛn ɔl. Nɔ brok, krɔs, ɔ chew dɛn.
- Tɛl yu dɔktɔ bɔt ɔl di ɔda mɛrɛsin dɛn, vaytamɛn dɛn, ɛn sɔpɔtmɛnt dɛn we yu de tek.
- Go to dɔktɔ wantɛm wantɛm if yu gɛt blɔd we nɔ kɔmɔn, yu gɛt brus, yu de si chenj, ɔ yu bɛlɛ de at bad bad wan.
- I impɔtant fɔ avɔyd bɛlɛ we yu de tek dis mɛrɛsin ɛn fɔ wan wik afta yu dɔn stɔp. Yuz wan we we pɔsin kin abop pan fɔ kɔntrol bɔn pikin.
- If yu gɛt ɛni kwɛstyɔn bɔt dis mɛrɛsin, nɔ ɛva shem fɔ tɔk to yu dɔktɔ.
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