Yu de tek mɛrɛsin fɔ pwɛl hat, wɔri, ɔ ɔda mɛrɛsin? Dɔn dis atikul rili impɔtant to yu. Sɔntɛnde, wan ɔ mɔ mɛrɛsin we wi kin tek kin mek wi bɔdi mek tumɔs wan kemikal we dɛn kɔl sɛrotonin. Dis na wetin dɔktɔ dɛn kin kɔl sɛrotonin syndrome . Pan ɔl we di nem kin tan lɛk se i kɔmplikt we yu luk am fɔs, na sɔntin we wi ɔl nid fɔ no. Lɛ wi tek tɛm luk wetin i bi, wetin mek i denja, ɛn aw wi go protɛkt wisɛf.
Fɔs, wetin na Serotonin?
Fɔ tɔk am simpul wan, sɛrotonin na kemikal we wi bɔdi de mek insay wi. Fɔ tɔk di kɔrɛkt tin, i tan lɛk smɔl mɛsenja we de kɛr mɛsej bitwin di sɛl dɛn na wi nervɔs sistɛm. We wi de tɔk bɔt mɛrɛsin, wi kin kɔl dis nyurotransmit.
I de du bɔku impɔtant wok dɛn na wi bɔdi. Fɔ ɛgzampul:
- I de kɔntrol yu gladi at ɛn di we aw yu de fil .
- I de ɛp yu fɔ slip fayn .
- I de mek pɔsin ebul fɔ mɛmba ɛn lan fayn fayn wan .
- I de kɔntrol di tɛmpracha na di bɔdi .
- Fɔ it kin mek pɔsin want fɔ it .
Bɔku pipul dɛn kin tink se na di bren nɔmɔ dɛn kin si sɛrotonin. bכt infakt, 90% pan di sεrotonin na wi bכdi de fכn insay di gכt. na lεk 10% nכmכ de prodyuz na di bren. Risach pipul dɛm biliv se wan pan de tin dɛm wae kin mek pɔrsin gɛt sik lɛk pwɛl hat na wae di sɛrotonin lɛvɛl na di bren kin go dɔŋ. Bɔt if dis bɔku pasmak, i kin mek di nerve sɛl dɛn wok pasmak ɛn mek dɛn gɛt sayn dɛn we denja. Dis na wetin wi kin kɔl sɛrotonin sindrom.
Wetin na di sayn dɛm wae de sho se yu gɛt sɛrotonin syndrome?
Dɛn simptom ya kin apin insay sɔm awa afta yu dɔn bigin fɔ tek nyu mɛrɛsin we de afɛkt di sɛrotonin lɛvɛl, ɔ yu dɔn inkrisayz di doz fɔ wan mɛrɛsin we dɔn de.
| Di kɔmɔn sayn dɛm | |
|---|---|
| Di chenj dɛn we de apin na di maynd ɛn di we aw pɔsin de biev | Kɔnfyushɔn, nɔ rɛst, agiteshɔn. |
| Di chenj dɛn we kin apin na di bɔdi | di pupil dεm we dilayt, ed we de at, chenj na di bכdi prεshכn εn di bכdi tεmprachכ, nכs, vכmit, dayariya. |
| Simptom dɛm wae gɛt fɔ du wit di nervɔs sistɛm | Di at kin bit kwik kwik wan, i kin shek, i nɔ kin ebul fɔ kɔntrol di mɔsul dɛn ɔ i kin twitch, di mɔsul dɛn kin stif, i kin fil kol ɛn klem, ɛn i kin swet pasmak. |
| Atɛnshɔn: Dɛn tin ya na siriɔs sayn dɛn we kin mek pɔsin in layf de pan denja! | |
| Rili ay fiva, siz, at bit we nɔ de bit ɔltɛm, pas aut. | |
If yu gɛt ɛni wan pan dɛn sayn ya : fiva we rili ay, yu kin gɛt sik, yu at nɔ kin bit ɔltɛm, ɔ yu nɔ kin no natin , na mɛdikal imejensi. Go na ɔspitul in Imejɛnsi Dipatmɛnt (ETU) wantɛm wantɛm ɔ kɔl ambulans. Dis kin kil pɔsin if dɛn nɔ trit am kwik kwik wan.
Wetin kin mek pɔsin gɛt dis sik?
Bɔku tɛm, dis kin apin bikɔs ɔf mɛrɛsin, mɔ we dɛn yuz tu ɔ mɔ mɛrɛsin dɛn we de afɛkt di sɛrotonin lɛvɛl togɛda.
Di men tin dɛn we du di bad tin: Dɛn kin yuz mɛrɛsin fɔ mek pɔsin nɔ fil bad
- SSRI (Selective Serotonin Reuptake Inhibitors): Dɛn wan ya na di kayn mɛrɛsin we dɛn kin gi mɔ fɔ mek dɛn nɔ gɛt pwɛl hat. Dɛn kin mek di sɛrotonin lɛvɛl na di bren go ɔp. Ɛgzampul dɛn: `Sitalopram`, ` Ɛsitalopram (Lɛksapro)`, `Fluɔksɛtin (Prozak)`, `Sɛtralin (Zoloft)`.
- SNRI dεm (Serotonin εn Norepinephrine Reuptake Inhibitors): Dis na כda kayn antidipreshכn. Ɛgzampul dɛn: `Dulɔksɛtin (Cymbalta)`, `Vɛnlafaksin (Ɛfɛksɔ)`.
- MAOIs (Monoamine Oxidase Inhibitors): Dɛn wan ya na wan kayn mɛrɛsin we dɔn ol smɔl, bɔt stil pawaful.
Ɔda mɛrɛsin, sɔpɔtmɛnt, ɛn drɔgs we de mek di sik bɔku
- Pen kila: Sɔm strɔng pen kil, mɔ di opioid lɛk Tramadol ɛn Fentanyl.
- Maygren mɛrɛsin (Triptans): Ɛgzampul: `Sumatriptan (Imitrex)`.
- Sɔm mɛrɛsin fɔ kɔf: Kɔf srɔp we gɛt `Dextromethorphan`.
- Di mɛrɛsin dɛn we de agens nɔs: Ɛgzampul dɛn: `Mɛtɔklɔpramid (Reglan)`, `Ondansetron (Zofran)`.
- Herbal supliment: Risk de wae yu tek tin lek St. John’s wort en Ginseng wit antidepressant.
- Ilɛgal drɔgs: Fɔ yuz drɔgs lɛk Ecstasy (MDMA), LSD, Cocaine, ɛn Amphetamines wit antidipreshan kin rili denja.
Aw dɔktɔ kin no bɔt dis?
No wan tɛst nɔ de we go tɛl yu fɔ tru wetin dis na. Yu dɔktɔ go no dis sik bay we i aks yu kwɛstyɔn ɛn chɛk yu.
I rili impɔtant fɔ tɛl yu dɔktɔ bɔt ɛvri mɛrɛsin, vaytamɛn, ɛbul sɔpɔtmɛnt, ɛn ivin di mɛrɛsin dɛn we yu de tek we nɔ rayt. Yu dɔktɔ de fɔ ɛp yu, nɔto fɔ jɔj yu. Di kɔrɛkt diagnosis ɛn tritmɛnt dipen pan di infɔmeshɔn we yu gi.
Yu dɔktɔ kin ɔda fɔ du blɔd tɛst, urine tɛst, ɛn sɔntɛm CT skan fɔ mek shɔ se nɔ ɔda mɛrɛsin nɔ de (e.g., infɛkshɔn, ɔt strok).
Aw dɛn kin trit am?
Di we aw dɛn de trit yu kin dipen pan aw yu sik bad bad wan.
Di fɔs ɛn impɔtant tin na fɔ stɔp di mɛrɛsin we mek dis sik.
- Smɔl smɔl sayn dɛm: Bɔrku pipul dɛn kin fil fayn insay 24 awa afta dɛn dɔn stɔp di mɛrɛsin wae mek dɛn gɛt de sik. Yu dɔktɔ kin kip yu na ɔspitul fɔ mek dɛn wach yu.
- Mɔdaret simptom dɛm: I kin nid fɔ de na ɔspitul ɛn wach fɔ at le 24 awa.
- Di bad bad sayn dɛm: Na dis tɛm, yu kin nid fɔ admit yu na di intensiv kia yunit (ICU) fɔ gɛt tritmɛnt. Na ya, dɛn kin wach tin dɛn lɛk at rit ɛn blɔd prɛshɔn ɔltɛm.
Di tritmɛnt dɛn kin bi:
- Mεdikeshכn dεm we de blכk sεrotonin prodakshכn: fכ egzampl, mεdikeshכn dεm lεk `Cyproheptadine`.
- Di mɛrɛsin dɛn we de mek di mɔsul rilaks ɛn we de mek pɔsin wɔri: Bɛnzodiazepin, lɛk Dayazepam (Valium).
- Mɛrɛsin dɛn we de kɔntrol di at rit ɛn blɔd prɛshɔn.
- Ɔksijɛn ɛn salin (Intravenous - IV fluids): Fɔ kɔntrol di wata we de kɔmɔt na di bɔdi ɛn fiva.
Aw wi go protɛkt wisɛf frɔm dis kayn tin?
Dis na sɔntin we bɔku tɛm dɛn kin avɔyd. Sɔm tin dɛn de we yu nid fɔ du.
- Tɛl yu dɔktɔ se:Tɛl yu dɔktɔ bɔt ɛvri mɛrɛsin, vaytamɛn, ɛn ɛbul sɔpɔtmɛnt we yu de tek. Dis impɔtant mɔ if yu de tek mɛrɛsin frɔm bɔku dɔktɔ dɛn.
- Yu fɔ no bɔt di sayn dɛm: If yu de tek pas wan mɛrɛsin wae de afɛkt di sɛrotonin, no bɔt di sayn dɛm wae de sho se yu gɛt sɛrotonin syndrome. If ɛni sayn de sho, yu kin no am kwik kwik wan.
- Nɔ stɔp fɔ tek yu mɛrɛsin wantɛm wantɛm: Nɔ stɔp fɔ tek ɛni mɛrɛsin wantɛm wantɛm ɔ chenj di doz we yu nɔ tɔk to yu dɔktɔ.
- Aks if yu gɛt kwɛstyɔn: If yu gɛt ɛni kwɛstyɔn ɔ dawt bɔt wan mɛrɛsin, aks yu dɔktɔ.
Mɛsej we dɛn kin kɛr go na os
- Serotonin syndrome na wan sik we kin mek pɔsin in layf de pan denja we kin kam bikɔs ɔf di bɔku bɔku kemikal we de na di bɔdi we de na di bɔdi.
- Di men rizin fɔ dis na di kɔmbayn ɔ inkris doz fɔ sɔm mɛrɛsin dɛm, lɛk antidipreshan.
- Wach fɔ sɔm sayn dɛm lɛk wae yu nɔr de rɛst, yu de shek shek, yu de swet pasmak, ɛn yu at de bit kwik kwik wan.
- If yu gɛt siriɔs sayn lɛk ay fiva, siz, ɔr yu nɔr de no natin, tek am se na imejensi ɛn go na ɔspitul in Imejɛnsi Tritmɛnt Yunit (ETU) wantɛm wantɛm.
- Dis risk kin bi bɔrku wan if yu tɔk ɔnɛs wan wit yu dɔktɔ bɔt ɔl di mɛrɛsin ɛn sɔpɔtmɛnt dɛm wae yu de tek.
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