Yu no bɔt Siklɔs Kraysis? Lɛ wi tɔk bɔt dis sik we de mek wi fil pen!

If yu gɛt siklɛt sik, yu go dɔn yɛri ɔ yu dɔn gɛt pen wantɛm wantɛm ɛn bad bad wan. Dis na wetin wi kin kɔl siklɛt sik. I kin rili mek yu at pwɛl ɛn i kin mek yu fil pen. Bɔt nɔ wɔri, wi go tɔk bɔt am ditayli tide.

Wetin na dis sik we de mek pɔsin sik?

Fɔ tɔk am simpul wan, siklɛt sik na we yu bɔdi in ‘sikl sɛl’, ɔ rɛd blɔd sɛl dɛn we tan lɛk sik, kin stɔp na blɔd vesel, we kin mek di blɔd flɔ slo ɔ stɔp. Yu no, na wi rɛd blɔd sɛl dɛn de kɛr ɔksijɛn ɔlsay na di bɔdi. So, we yu gɛt siklɛt sik, yu tisu ɛn ɔgan dɛn nɔ kin gɛt inof ɔksijɛn. Dis kin mek yu fil bad bad wan ɛn ɔda prɔblɛm dɛn .

Tink bɔt am lɛk we smɔl dɔti kin stɔp na wata paip, di wata kin slo. Bɔt wetin kin stɔp ya na dɛn rɛd blɔd sɛl dɛn de we tan lɛk sik. Dɛn tin ya nɔ kin bɛn izi wan lɛk di rɛgyula rawnd rɛd blɔd sɛl dɛn, ɛn dɛn nɔ kin slip tru smɔl smɔl say dɛn. Na dat mek dɛn kin tray fɔ stɔp.

Sɔmtɛm dɛn kin mɛn dis sik na os, bɔt if de sik tranga, yu kin nid fɔ de na ɔspitul fɔ sɔm dez fɔ tritmɛnt.

Wetin na di kayn sik dɛm wae gɛt sik?

Fכ men kayn sik dεm de fכ sik. Lɛ wi tek wan luk pan wetin dɛn bi:

• Vaso-occlusive crisis: Dis na di kayn we we dɛn kin gɛt mɔ. Wetin kin apin ya na dat siklɛt sɛl dɛn kin stɔp na yu kapilari ɔ ɔda smɔl smɔl blɔd vesel dɛn, ɛn dis kin mek blɔd nɔ go na yu tisu ɛn ɔgan dɛn. Dis na de tin wae kin mek pɔrsin fil bad bad wan. Ɔda kayn dɛn kin afɛkt sɔm patikyula say dɛn na di bɔdi.

• Aplastik kraysis: Dis na we yu bon mכro (di ples insay yu bon dεm we de mek blכd sεl dεm) de stכp fכ mek rεd bכdi sεl dεm wan wan. Dis kin kכz fכ sכm vayral infεkshכn dεm, spεshal wan parvovirus B19.

• Hyperhemolytic crisis: Dis na we yu hεmoglobin lεvεl (di protin we de insay rεd bכdi sεl dεm we de kכri כksijεn) de dכn wan wan. Dis na bikɔs yu rɛd blɔd sɛl dɛn de brok tu kwik. Dis kin apin bak afta dɛn dɔn transfyushɔn blɔd, we na kɔmɔn tritmɛnt fɔ siklɛt sik.

• Splenic sequestration: Dis na we sik sel dɛn kin stɔp na yu splin (wan ɔgan we de ɔp di lɛft say na yu bɛlɛ), we kin mek di splin big wantɛm wantɛm ɛn swel wit pen . Dis kin denja mɔ fɔ yɔŋ pikin dɛn, bikɔs bɔku blɔd kin gɛda na di splin, ɛn dis kin mek di blɔd nɔ bɔku.

Wetin na di sayn dɛm fɔ dis?

Di sayn dɛm fɔ siklɛt sik kin difrɛn difrɛn wan bay usay i afɛkt na di bɔdi. Di kɔmɔn sayn dɛm na:

• Diziz we pɔsin kin gɛt.
• Ekstrim taya, taya.
• Ed de at.
• Jaundice (di skin ɛn di yay dɛn we de yɔlɔ).
• Pen (dis na di men ɛn di sik we kin rili bad).
• I nɔ kin izi fɔ yu fɔ blo.
• Wik.

Di pen we sik kin gɛt kin bi dɔl, shap, chuk pɔsin, ɔ chuk pɔsin . I kin las fɔ sɔm awa, sɔm dez, ɔ ivin fɔ sɔm wiks. Di pen kin apin ɛnisay na di bɔdi, na wan ples ɔ na bɔku say dɛn. Fɔ ɛgzampul:

• Na di an ɔ di pal.
• Na di chɛst.
• Na di leg ɔ fut.
• Na di ɔda pat we de dɔŋ na di bak.
• Na di bɛlɛ.

Wetin mek dis siklɛt sik kin apin?

Siklɔs sik kin apin we di rɛd blɔd sɛl dɛn we tan lɛk sikl kin gɛda togɛda ɛn blok wan blɔd vesel. Bɔt nɔto ɔltɛm masta sabi pipul dɛn kin no bɛtɛ bɛtɛ wan wetin kin mek dis kin bigin.

Bɔt sɔm tin dɛn de we kin mek pɔsin gɛt dis sik:

• Di wata we nɔ de na di bɔdi : We di bɔdi nɔ gɛt wata, di blɔd kin tik ɛn di sɛl dɛn kin lɔk mɔ.
• Fɔ go na ay ay ples (bikɔs ɔksijɛn nɔ bɔku na ay ay ples).
• Infεkshכn : Eni infεkshכn, lεk kol כ flu.
• We uman gɛt bɛlɛ.
• Smok ɔ vaping.
• Fɔ du tin dɛn we yu kin du fɔ mek yu bɔdi wok tranga pasmak.
• Stress : Tin dɛm lɛk fɔ wɔri pasmak ɛn fɔ fred.
• Wantɛm we di tɛmpracha kin chenj we pasmak (e.g., fɔ tek kol shawa afta yu dɔn de na say we rili wam).
• Sɔm vaytamɛn dɛn we nɔ de, fɔ ɛgzampul fɔlet.

Us prɔblɛm dɛn dis kin mek?

Di kayn sik we sik sel kraysis kin tranga kin dipen pan usay di blɔd vesel we dɔn blok de. If di blɔd vesel dɛn blok na yu tisu ɔ ɔgan dɛn, prɔblɛm dɛn lɛk:

• Acute chest syndrome : Dis na siriɔs tin we kin mek pɔsin in layf de pan denja we kin apin na di chɛst. Di sayn dɛm na fiva, chɛst pen, ɛn i nɔ kin izi fɔ blo.
• Blɔd we de klɔt.
• Pen we nɔ de dɔn (pen we de kɔntinyu).
• di splin big ɛn ɔda sik dɛn we gɛt fɔ du wit di splin.
• Wund dɛn we nɔ de mɛn na di leg dɛn.
• Liva sik.
• Fɔ ɛgzampul, sik dɛn we kin kam na di lɔng, na di pulmonari haypatɛyshɔn.
• Nεkrכsis : di bon כ tisu dεm we de day (especially na ples dεm lεk di hip) bikoz fכ di bכdi we de fכlכ.
• di erekshכn dεm we de mek di penis de pen (dεn kכl am bak `priapism` insay man dεm).
• Strɔk : Na we di blɔd vesel we de gi blɔd to di bren blok ɔ brok.

Aw yu no dis?

If yu gɛt siklɛt sik, yu go mɔs dɔn go to yu dɔktɔ ɛvri 6 mɔnt ɔ wan tɛm insay di ia fɔ mek dɛn du yu blɔd tɛst. Bɔt if yu gɛt siklɛt sik, yu go nid fɔ gɛt ful sɛt fɔ lab tɛst. Dɛn tin ya kin bi:

• Blɔd tayp tɛst (if yu nid fɔ tek blɔd).
• CBC (Complete Blood Count) : Dis de mכsu di εmoglobin lεvεl εn di nכmba כf rεd εn wayt bכdi sεl dεm.
• CMP (Comprehensive Metabolic Panel) : Na wan komprehensiv set fכ mεtabolik tεst dεm we de luk pan di fכnshכn fכ כgan dεm lεk di kidni dεm εn di liva.
• Test fɔ di wok we di liva de du .
• rεtikulכsayt kכnt : dis de mכsu di nכmba fכ di nyu rεd bכdi sεl dεm we dεn fכm. Dis kin gi yu aidia bɔt aw di bon mɛro de wok fayn fayn wan.

Apat frɔm dat, yu dɔktɔ kin du wan kɔmplit bɔdi ɛgzamin ɛn imej tɛst dɛn lɛk:

• Doppler ultrasound : Si aw blɔd de flɔ tru di blɔd vesel dɛn.
• MRI : Ɛspɛshali if pɔsin de sɔprayz fɔ gɛt wan kɔndishɔn lɛk strok.
• Ultrasound : Fכ luk tin dεm lεk bכdi כgan dεm εn di splin.
• Chɛst X-ray : Fɔ chɛk fɔ wan kɔndishɔn lɛk akyu chɛst sindrom.

Aw dɛn kin trit am?

If yu gɛt siklɛt sik, yu kin nid mɛrɛsin fɔ mɛn yu pen fɔ ɛp fɔ kɔntrol di sayn dɛm wae nɔr kin fayn fɔ yu. If i nɔ izi, yu kin manej dis na os wit mɛrɛsin dɛn we yu kin bay na kɔt lɛk asetaminofɛn (e.g. Panadol®, Tylenol®) ɔ ibuprofen (e.g. Advil®, Brufen®).

Bɔt if yu fil bad bad wan, yu kin nid fɔ de na ɔspitul fɔ sɔm dez. Dɔn di dɔktɔ dɛn kin gi yu strɔng pen kil (lɛk mɔfin), IV wata (fɔ mek yu blɔd kɔntinyu fɔ flɔ fayn), ɛn ɔksijɛn if nid de.

Apat frɔm dat, di tritmɛnt fɔ siklɛt sik kin difrɛn difrɛn wan bay di pat dɛn na di bɔdi we di sik afɛkt ɛn aw di sik kin tranga. Dɔktɔ dɛn kin yuz mɛrɛsin, blɔd transfyushɔn, bon mɛro transplant, ɔ wan kɔmbayn tritmɛnt dɛn.

Mεdikeshכn dεm fכ mεnejmεnt fכ lכng tεm

Bɔku kayn mɛrɛsin dɛn de we dɔktɔ dɛn kin yuz fɔ mɛn siklɛt kraysis fɔ lɔng tɛm ɛn fɔ ridyus di frɛkuɛns we dɛn kin gɛt:

• Hydroxyurea: Dis mɛrɛsin de mek yu rɛd blɔd sɛl dɛn big, i de mek dɛn ebul fɔ fold mɔ ɛn mɔ, ɛn i de mek wan kayn ɛmoglobin we dɛn kɔl fetal ɛmoglobin bɔku. dis de mek di sεl dεm nכ de kכlכt.
• Krizanlizumab `(Krizanlizumab)`: .Dis na wan kayn monoklonal antibodi. I kin mek yu rɛd blɔd sɛl dɛn nɔ stik na di wɔl dɛn na yu blɔd vesel dɛn.
• L-glutamine: Dis na amino asid we de ɛp fɔ ridyus di damej pan rɛd blɔd sɛl dɛn.
• Voxelotor: Dis mεdisin de mek yu rεd bכdi sεl dεm nכ sik εn stik togeda.

Blɔd we dɛn kin gi pɔsin

Dɔktɔ dɛn kin yuz blɔd transfyushɔn fɔ trit aplastik ɔ haypa ɛmolaytik sikɛl sɛl kraysis. Dis tritmɛnt kin mek yu wɛl bɔdi rɛd blɔd sɛl dɛn ful-ɔp ɛn i kin mek yu nɔ gɛt siklɛt kɔmplikeshɔn dɛn. Sɔm pipul dɛn kin nid fɔ tek blɔd bɔku tɛm.

Transplant dɛn we dɛn kin du

Bɔn mɛro transplant ɔ stem sɛl transplant kin bi di wangren we fɔ mɛn siklɛt sik insay sɔm kes dɛm. Bɔt fɔ fɛn pɔsin we fit fɔ gi mɔni (lɛk brɔda ɛn sista) kin tek sɔm tɛm. כlso, bon mכro transplant kin mek כda siriכs komplikashכn dεm, lεk graft vs. host disease (GvHD). Fɔ dis rizin, dɔktɔ dɛn nɔ kin du bon mɛrɔ transplant we dɛn de trit siklɛt kraysis. Bifo dat, di men gol na fɔ trit yu sik dɛn ɛn fɔ mek yu nɔ fil pen.

Yu tink se dɛn go ebul fɔ stɔp dis?

Dɛn nɔ kin ebul fɔ avɔyd sikl sɛl kraysis ɔltɛm. Bɔt sɔm tin dɛn de we kin ɛp fɔ ridyus di prɔblɛm:

• Nɔ smok kpatakpata.
• If yu de na say we kol, drɛs fayn. Kol kin mek di blɔd vesel dɛn stɔp ɛn mek pɔsin gɛt prɔblɛm.
• Limit ɔ stɔp fɔ drink rɔm ɔltogɛda . Alkol kin mek di wata nɔ de igen.
• Drink at le 8-10 glas wata wan de (stay hydrated).
• Tek fɔlik asid tablɛt ɛvride fɔ mek yu gɛt mɔ rɛd blɔd sɛl (dɛn fɔ du dis lɛk aw di dɔktɔ advays yu).
• Was yu an wit sop ɔltɛm fɔ mek yu nɔ gɛt di sik.
• Gɛt ɔl di vaysin dɛn we yu nid di rayt tɛm (e.g. flu vaksin, nyumonia vaksin).
• Nɔ ɛksesaiz pasmak, bɔt i fayn fɔ du ɛksɛsayz we yu de du smɔl smɔl.
• Fɛn we fɔ ridyus strɛs (e.g. yoga, meditashɔn).

Aw a kin tek kia ɔf misɛf (we kraysis apin)?

If yu ɔ pɔrsin wae de nia yu gɛt sik sik, wae yu du dɛn tin ya, dat kin ɛp fɔ mek yu nɔr gɛt di sik:

• Kip yu wam wam. If yu was ɔt ɔ put ɔt pad na di say we yu de fil, dat go mek yu blɔd vesel dɛn big ɛn i go mek yu blɔd flɔ fayn. Di ɔt go ɛp bak fɔ mek di mɔsul dɛn we de at kol.(Nɔ put ays pak. Kol kin mek yu gɛt pen. So i bɛtɛ fɔ mek yu wam as yu ebul.)
• Drink bɔku wata. We yu drink bɔku wata, yu rɛd blɔd sɛl dɛn nɔ kin stik togɛda bɛtɛ, ɛn dis kin mek dɛn ebul fɔ muv na di chanɛl dɛn izi wan.
• Gɛt wan masaj. If yu masaj am saful wan, i kin mek yu blɔd flɔ mɔ, i kin mek yu mɔsul dɛn rilaks, ɛn i kin mek yu nɔ fil pen.
• Praktis fɔ tink gud wan. Risach dɔn sho se if yu pe atɛnshɔn pan wan gol fɔ shɔt tɛm, dat kin ɛp fɔ pul yu bren ɛn ridyus di pen we kin kam wit siklɛt sik. Ivin sɔntin we simpul lɛk fɔ pe atɛnshɔn pan aw yu de blo kin ɛp.
• Tek mɛrɛsin dɛn we de mek pɔsin fil pen we yu nɔ de bay. dis dεm na paracetamol, ibuprofen, כ naproxen (e.g. Aleve®). Bɔt nɔ tek pas wetin yu dɔktɔ tɛl yu fɔ tek.

Ustɛm yu fɔ go na di Imejɛnsi Tritmɛnt Yunit (ETU) ?

If yu gɛt ɛni wan pan dɛn sik ya, go to di Imejɛnsi Dipatmɛnt (ETU) we de nia yu wantɛm wantɛm :

* If yu gɛt sɔd, bad bad pen we yu nɔ go ebul fɔ kɔntrol wit mɛrɛsin na os.

* I nɔ izi fɔ blo ɔ i kin gɛt pen na yu chɛst.

* Ay fiva (we i pas 101°F ɔ 38.3°C).

* I kin wik wantɛm wantɛm, i nɔ kin izi fɔ tɔk, i kin drɔp wan say na di fes (di sayn dɛn we de sho se pɔsin gɛt strok).

* Bɛlɛ de pen bad bad wan ɔ blo.

* If janda de bɔku.

* Fɔ man, di erection we de mek i fil pen kin las pas 4 awa.

Nɔ delay. If yu bigin tritmɛnt kwik, dat kin mek yu nɔ gɛt prɔblɛm dɛn we go de fɔ lɔng tɛm.

Di tin dɛn we impɔtant pas ɔl we yu nid fɔ mɛmba

If yu gɛt siklɛt sik, fɔ tink bɔt prɔblɛm kin mek yu nɔr fil fayn smɔl. Dɛn kayn tin ya kin mek yu gɛt sɔm kayn sik wae nɔr fayn ɛn kin mek yu gɛt prɔblɛm wit yu layf. If yu dɔn ɛva gɛt sik we de mek yu sik, yu no aw tɛm rili valyu.

If yu sik nɔr de bɛtɛ wit mɛrɛsin wae yu kin gɛt fɔ mɛn yu pen ɔr yu ɔspitul mɛrɛsin na yu os, na tɛm fɔ go to yu dɔktɔ. Dɛn de ya fɔ ɛp. Nɔr frayd fɔ tɔk to yu dɔktɔ bɔt yu sik. I bɛtɛ fɔ trit am kwik kwik wan. Wok wit yu dɔktɔ fɔ mek wan plan fɔ mɛn yu pen we go wok fɔ yu.

` Sikl Sεl Kraysis, Sikl Sεl Sik, Rεd Blɔd Sεl, Pen, Blɔd Vesɛl, Ɔksijɛn