By’olina okumanya ku ‘Statins’ okulwanyisa kolesterol

Okukeberebwa kw’omusaayi okwasembyeyo kwalaga nti kolesterol wo ali waggulu katono? Wawulira ng'otya katono n'okweraliikirira bwe walaba nga "bad cholesterol" oba LDL level yo nayo eri waggulu? Bwe kiba bwe kityo, omusawo ayinza okuba nga yakulagidde okutandika okumira eddagala ery’ekika kya ‘Statin’. Kale leero, ka twogere mu ngeri ennyangu ennyo ku ‘Statins’, ezikulu eri abantu bangi.

Okay, bano ‘Statins’ be batya?

Mu ngeri ennyangu, 'Statins' kika kya ddagala abasawo lye bakuwa okukendeeza ku kolesterol mu musaayi gwo naddala kolesterol "omubi".

Bwe twogera ku kolesterol, bulijjo tuwulira ebika bibiri, nedda?

1. LDL (Low-Density Lipoprotein): Kino kye tuyita kolesterol "omubi" . Lowooza ku misuwa gyo nga payipu etambuza amazzi. Kolesterol ono owa LDL ky’akola kwe kuteeka ng’ebisasiro ebirimu amafuta munda mu payipu eyo, n’akendeeza mpolampola ekkubo omusaayi we gukulukuta. Ebika bya ‘statins’ ebimu bisobola okukendeeza ku kolesterol ono omubi ebitundu 50% oba okusingawo.

2. HDL (High-Density Lipoprotein): Kino kye tuyita kolesterol "omulungi" . Asitula kolesterol omubi abadde azimba mu misuwa n’amutuusa mu kibumba okuggyibwa mu mubiri. Kiringa omusolooza wa kasasiro.

Statins tezikoma ku kukendeeza ku kolesterol omubi owa LDL, naye era ziyamba okukendeeza ku triglycerides, ekika ekirala eky’amasavu mu musaayi, n’okwongera katono ku kolesterol ennungi eya HDL.

Eddagala lino litera okulagirwa okumira omulundi gumu olunaku, mu kiseera kye kimu. Statin ezimu zikola bulungi nga zimira ekiro. Kino kiri bwe kityo kubanga emibiri gyaffe gikola kolesterol mungi ekiro. Kyokka, ebirungo ebimu ebipya ebiyitibwa statins bikola bulungi nnyo bwe bimira essaawa yonna ey’olunaku. Omusawo wo ajja kukunnyonnyola kino.

Eddagala lino likola litya munda mu mubiri?

Eno mboozi nnyuvu nnyo. Teebereza nti ekibumba kyo kye kkolero erisinga okukola kolesterol. Mu butuufu, ebitundu 75% ku kolesterol omubiri gwaffe gwe gwetaaga akolebwa mu kibumba kyaffe. Ebisigadde biva mu mmere gye tulya.

Kale, ekibumba kirina enziyiza eyeetaagibwa ennyo mu nkola eno ey’okukola kolesterol. Kiyitibwa `HMG-CoA reductase`. Eddagala lya `Statin` likola ng'omukuumi w'omulyango, nga liziyiza enziyiza ya `HMG-CoA reductase` okutuuka mu kibumba. Olwo ekibumba ne kifiirwa ekigimusa ekyetaagisa okukola kolesterol. N’ekyavaamu, obungi bwa kolesterol akolebwa ekibumba bukendeera nnyo. Otegedde?

Lwaki twetaaga ‘Statins’?

Ensonga enkulu kwe kukendeeza ku bulabe bw’okulwala omutima n’okusannyalala.

Nga bwe nnagambye emabegako, kolesterol omubi bwe yeeyongera mu musaayi, afuna okuteekebwa ku bisenge by’emisuwa. Mu busawo, kino tukiyita ‘Atherosclerosis’ . Kolesterol azimba mu ngeri eno ayitibwa ‘plaque’. Kino kikendeeza ku kifo ekiri munda mu misuwa ne kiremesa omusaayi okutambula.

Teebereza kiki ekibaawo singa omusuwa ogugabira omutima omusaayi guzibikira bwe guti? Omutima tegufuna mukka gwa oxygen n’ebiriisa bye gwetaaga. Ekyo kivaako omutima okulwala. Era singa ‘plaque’ eno ekutuka mu musuwa ogugaba omusaayi mu bwongo ne wabaawo ekizimba ky’omusaayi, kireeta okusannyalala.

Statins zikendeeza ku kolesterol, ekikendeeza nnyo ku bulabe bw’embeera zino ez’obulabe.

Bika ki ebya ‘statins’ ebisinga okukozesebwa?

Waliwo ebika bya ‘statins’ ebiwerako. Omusawo ajja kukuwa ekika ekisinga okukusaanira, ng’alowooza ku mbeera y’obulamu bwo, kolesterol n’ebintu ebirala.

Oluusi ‘statin’ ejja mu ddagala lye limu n’eddagala eddala. Okugeza eddagala eriyitibwa ezetimibe nga lirimu eddagala lya simvastatin.

Ani alagirwa okumira ‘Statins’?

Omusawo ajja kukuwa eddagala lya statin okusinziira ku bulabe bw’olina okulwala omutima okutwalira awamu. Kino kisinziira ku bintu bingi omuli emyaka gyo, ekikula kyo, ebyafaayo by’amaka go, n’okumanya oba onywa sigala. Statins zitera okusemba abantu bano wammanga:

• Ku abo abatasobola kukendeeza ku kolesterol waabwe (naddala LDL asukka 190 mg/dL) wadde nga balya emmere n’okukola dduyiro .
• Ku bantu abalina obulwadde bwa sukaali era abali wakati w’emyaka 40-75, nga balina LDL cholesterol esukka 70 mg/dL.
• Ku abo abaafuna edda obulwadde bw’omutima, okusannyalala, oba obulwadde bw’emisuwa egy’okumpi (PAD) .
• Ku bantu ab’emyaka 40-75 abalina LDL esukka 70 mg/dL, abali mu bulabe obw’amaanyi obw’okufuna endwadde z’omutima.
• Singa omuntu mu maka (abazadde, baganda be) aba n’obulwadde bw’omutima ku myaka emito era ng’alina kolesterol omungi.

Waliwo ebizibu byonna ebiva mu kino?

Kino kizibu eri abantu bangi. Kituufu nti, okufaananako n’eddagala lyonna, eddagala lya statins liyinza okuba n’ebizibu ebivaamu. Naye ekikulu abantu abasinga tebafuna buzibu bwonna. N’ebizibu ebitonotono ebibaawo bijja kuggwaawo ng’eddagala ligenda mu maaso.

Ekikulu: Bw’ofuna ebizibu byonna, tolekera awo kumira ddagala lyo ku bubwo. Ekisinga obulungi kwe kwogera n’omusawo wo ku nsonga eno. Oyinza okugonjoola ekizibu kino ng’okyusa ekika kya statin ky’omira oba ng’okyusakyusa mu ddoozi.

Waliwo abantu abatalina kumira ddagala lya statins?

Yee. Statins tezikirungi ku bakyala ab’embuto, bamaama abayonsa, n’abantu abalina endwadde ezimu ez’amaanyi mu kibumba. Olina n’okubuulira omusawo wo ku ddagala eddala lyonna ly’omira. Omubisi gw’ebibala naddala omubisi gw’emizabbibu n’amakomamawanga gusobola okukwatagana n’ebimu ku biyitibwa statins, n’olwekyo buuza omusawo wo ku nsonga eyo nakyo.

Kiki ekibaawo singa olekera awo okumira eddagala?

Bw’omala okulekera awo okumira eddagala lya Statin, kolesterol wo adda waggulu we yali. Ekyo kitegeeza nti obulabe bwo obw’okulwala omutima n’okusannyalala budda waggulu. Kale ebiseera ebisinga kiba ddagala lya bulamu bwonna.

Ddi lw’olina okulaba omusawo mu bwangu

Bw’ofuna obubonero bumu ku buno wammanga ng’omira eddagala lya Statin, genda mangu omusawo amagezi.

• Bw’owulira nga togumiikiriza, obulumi obw’amaanyi oba obunafu mu binywa oba ennyondo.
• Bwoba olina obulumi mu mubiri nga olina omusujja .
• EbibyoSinga amaaso go oba olususu lwo lulabika nga lwa kyenvu (jaundice).
• Singa omusulo gwo gufuuka langi enzirugavu nga caayi ebikoola amazzi .

Mu mbeera ng’eyo, kirungi okugenda mu ddwaaliro ekikola ku bujjanjabi obw’amangu (ETU).