I thluak leh i ruhroah harsatna i nei nghal em? ADEM (Acute Disseminated Encephalomyelitis) chungchang hi i zir dawn teh ang!

`ADEM` (Acute Disseminated Encephalomyelitis) tih thumal hi i hre tawh em? Hei hi i tan chuan thil thar a ni mai thei. Thil awm lo tak a ni a, mi tlemte chauh a nghawng tihna a ni a, mahse a lo lang nghal thei a, kan nervous system a nghawng thei bawk. Ngaihtuah buai suh, awlsam takin kan sawi dawn a, i hriatthiam theih dan tur angin.

ADEM chu eng nge ni? A awlsam zawngin i hrethiam ang u.

A awlsam zawngin ADEM hi kan Central Nervous System – chu chu thluak leh ruhro (spinal cord) a inflammation emaw swelling emaw a lo awm nghal mai a ni. Think of it this way, just like when we get an injury , kan taksa a lo hring chhuak a, hei hian thluak leh ruhro hmun thenkhatah a hring chhuak thin.

He inflammation hian kan nerve fibers vel a protective sheath chu a tichhia thei a ni . He sheath hi myelin sheath an ti a . Electric wire vel plastic khuh ang mai a ni. Message te chu nerve-ah a kal chak zawk nan a pui thin. Chuvangin, he myelin sheath hi a chhiat chuan nerve message te hi a kal tha tawk lo. Chutah chuan symptom hrang hrang a lo lang thin. Doctor thenkhat chuan he natna hi "demyelinating" an ti bawk.

ADEM-a "acute" tih thumal hian a lo awm nghal tihna a ni . A tam zawkah chuan dam chhungin vawi khat chauh a thleng thin. Mahse, a lo lang leh thei lo hle.

Hei hi engtiang chiahin nge a hluar?

ADEM hi a takah chuan a awm lo hle a ni . Survey-ah chuan America ang ramah hian mi maktaduai hnih leh a chanve zinga pakhat velah a awm tih a tarlang. Chuvangin, hei hi mi zawng zawng tuar thei natna a ni lo.

Hetiang natna lan chhuah dan hi engte nge ni?

ADEM symptoms hi virus emaw bacteria emaw infection atanga ni engemaw zat hnuah a lang tlangpui . Heng symptoms te hi mi hrang hrangah a inang lo thei a, thluak emaw spinal cord emaw a inflammation awmna hmun ah pawh a innghat bawk.

A lan chhuah dan tlangpui thenkhat chu:

• Khawsik
• Lu na.
• Nausea emaw, luak chhuak emaw
• Rilru tibuai
• Chau

Chu bakah, nervous system nena inzawm symptoms te chu:

• Ke ruh leh ke ruh (limbs) emaw, tingling sensation emaw a awm
• Chaw ei harsat
• Mit hmuhna hloh emaw, hmuh fiah lo emaw (optic neuritis) .
• Muscle chak lohna
• Kal harsat
• Seizures a awm thin

I hmuh angin, heng natna lan chhuah dan leh a nasat dan hi mi hrang hrangah a inang lo hle thei a ni . Mi thenkhat chuan symptoms na lo tak tak an nei thei a, thenkhat erawh chuan na zawkin an tuar thei thung.

Engvangin nge hetiang hi a lo awm? ADEM awm chhante chu engte nge ni?

ADEM awm chhan dik tak hi hriat a la ni lo . Mahse, zirchianna chuan virus emaw bacteria emaw kan taksaa a luh chuan kan immune system hian a do let thin tih a tarlang. Mahse, ADEM vei miah chuan immune system chuan a central nervous system hmun thenkhat chu a bei sual a ni . Hmelma anga ngaiha mahni member pakhat beih ang mai a ni. He attack dik lo hian a hmaa kan sawi tawh ang khan inflammation (swelling) a siam a, chu chuan a symptoms a siam leh thin.

ADEM vei zinga 70% leh 80% inkar chuan ADEM symptoms a lan hmain infection emaw natna emaw an nei tih hmuhchhuah a ni. ADEM symptoms hi a kai atanga ni 7 atanga ni 14 hnuah a intan tlangpui. ADEM nena inzawm thei natna tlanglawn thenkhat chu:

• Influenza emaw Flu emaw a ni thei
• Measles natna a ni
• Mumps a awm
• Rubella chuan a rawn ti a
• Vawk natna (Chickenpox) a awm
• Epstein Barr virus a ni
• Cytomegalovirus hmanga natna hrik pai a ni
• Herpes simplex virus (`Herpes simplex virus`) a ni a, a natna hi a lar hle.

Bacteria, virus leh hri kai chi hrang hrang ADEM nena inzawm ni mah se, natna hrik pakhat chauh avanga lo awm niin a lang lo.

Tun hnaiah ADEM thlentu dang, a bik takin naupangte zingah Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease (MOGAD) tih hmuhchhuah a ni bawk. Hei hi autoimmune condition anga ngaih a ni bawk. Chumi awmzia chu taksain a taksain a taksain a nervous system a bei tihna a ni. He MOGAD hian a chang chuan ADEM a thlen thei bawk.

Tute nge ADEM vei theihna chance sang zawk?

Tu pawhin ADEM an dawng thei. Mahse, puitling aiin naupangah a tam zawk deuh . Tin, tun hnaia hri kai i neih chuan ADEM vei theihna chance a sang deuh thei bawk.

ADEM avanga harsatna awm thei te chu engte nge ni?

ADEM hian harsatna engemaw zat a thlen thei a, chung zingah chuan:

• Hriatrengna hloh
• Cognitive processing tihkhawtlai a ni
• Coma ah a awm

A tlem hle a, ADEM symptoms hi a nasat chuan nunna atana hlauhawm thei a ni. Mahse chu chu a tlem hle .

Mi thenkhat chuan enkawlna hnuah pawh symptom thenkhat an nei thei a:

• Lu na na tak.
• Numbness a awm
• Coordination lama harsatna a awm
• Mit hmuh a fiah lo

Engtin nge ADEM hi hmuhchhuah a nih?

ADEM natna lan chhuahna i neih chuan doctor chuan i dinhmun chanchin kimchang takin a la ang a, i natna lan chhuah dante a zawt ang a, ADEM i vei leh neih loh hriat nân neurological examination , general physical exam, leh test dang engemaw zat a ti ang.

Test hi ADEM thlentu ni thei tur underlying condition dang, MOGAD ang chi te enfiah nan an ti bawk. ADEM hriat theihna atana test hman tlanglawn tak takte chu thisen test leh:

• MRI scan a ni
• Spinal fluid test a ni

MRI test hian eng nge a zawn?

MRI (Magnetic Resonance Imaging) hi imaging technique bik a ni a, thluak chhung thuk takah inthlak danglamna a zawng thei a ni. Doctor-te chuan ADEM vanga hliam emaw, hliam emaw chu central nervous system hmunpui pathum: thluak, ruhro leh mit nerve-ah te an zawng thin.

• White matter : Hei hi nerve fibers te myelin in a khuh na hmun a ni. Hengte hi MRI-ah chuan a var angin a lang.
• Gray matter : Hei hian nerve cell taksa a pai a. MRI-ah chuan myelin an tlakchham avangin an thim hmel hle.

MRI hmasa ber atanga thla engemaw zat hnuah doctor chuan MRI dang a order leh thei a, hun kal zelah heng hmunte hi engtin nge a inthlak danglam tih a en thei bawk.

Spinal fluid testing-ah hian eng nge zawn thin?

Hei hi lumbar puncture an ti bawk . Hei hi neurological symptoms awm chhan hriat nan test pawimawh tak a ni. I cerebrospinal fluid (CSF) tlemte ei a ngai a ni. CSF hi tui thianghlim, rawng nei lo a ni a, i thluak leh i ruhro chu a hual vel a, a humhim a, a chawm bawk.

ADEM-ah chuan cerebrospinal fluid-ah hian thisen var, a bik takin lymphocytes a tam zawk a ni. Heng cell te hi kan immune system active part an ni. He CSF sample hi heng cell te hian ADEM thlentu nia ngaih bacteria emaw virus emaw an chhan dan enfiah nan hman a ni a, neuroinflammatory natna dang a awm leh awm loh enfiah nan hman a ni bawk.

ADEM enkawl dan tur chu engte nge ni?

ADEM enkawlna tum ber chu thluak leh ruhro a inflammation tihziaawm a ni . A hnuaia enkawlnate hi hman theih a ni:

• Steroid damdawi teSteroid damdawi: ADEM enkawlna line hmasa ber chu intravenous (IV) steroid a ni. Hei hi ni engemaw zat chu thisenah pek theih a ni. Chumi hnuah ni engemaw zat chu oral steroid pills pek i ni thei bawk.
• Intravenous immunoglobulin (IVIG) : Hei hi donor thisen plasma atanga siam antibodies awmna damdawi a ni. Hei pawh hi vein-ah pek a ni.
• Plasma exchange (or plasmapheresis): Hei hian i thisen thenkhat lak a, i taksa hriselna tichak lotu thil thenkhat paih chhuaktu machine hmanga kalpui a, chu chu i taksaah dah leh a ni. He enkawlna hian darkar engemaw zat a daih thei a, vawi tam tak tih theih a ni bawk.

He natna chungchang hi zirchian belh zel a ni a, enkawlna thar pawh hmuhchhuah a ni bawk.

Heng enkawlnate hi i doctor-in a ruat a ni tih hre reng ang che. I dinhmun atana tha ber tur a thlang ang.

Heng enkawlnate hian side effect a nei em?

Enkawlna dang ang bawkin side effect thenkhat a awm thei bawk.

Hun rei lote chhunga steroid hmanga enkawlna hian a nghawng tha lo chu rei lo te chhung chauh a ni tlangpui a, mahse hengte hi a ni thei:

• Thisen sugar level a sang
• Potassium level a tlahniam
• Mut harsat
• Mood inthlak danglam (thinrim, tap, lungkham) .
• Rihna a sang chho zel
• A hmui a sen vek
• Ka chhungah metallic taste a awm tih hriat

`IVIG` enkawlna avanga side effect leh harsatna awm thei :

• Allergy a awm thei
• Infection awm thei te
• Thâwk harsa
• Thisen a chhuak thin
• Kidney a chhiat phah
• Lu na.

Plasmapheresis natna avanga harsatna awm thei :

• Remchan lohna
• Thisen chhuak
• Infection awm thei te
• Kidney a chhiat phah
• Taksa peng pakhata thisen pek tlem (`Ischemia`) .

Heng side effects te hi i doctor nen sawiho rawh. A tam zawkah chuan enkawl theih an ni.

Enkawl hnua dam leh theih nan eng chen nge a duh?

ADEM vei enkawl tam zawk chu enkawl an nih atanga ni engemaw zat chhungin an dam tan thin . Mahse, i natna lan chhuah dan nasat dan azirin a dam kim theih nan thla ruk vel a ngai thei . A tlem hle a, mi thenkhat chu an dam kim lo mai thei. Mahse, mi tam zawk chu an dam tha hle.

ADEM ven dan tur a awm em?

ADEM ven dan tur bik a awm lo . Mahse, virus leh bacteria infection (entir nan, kut sil fo leh damlo laka inthiarfihlim) laka inthiarfihlim dan tha tak tak i hman chuan i hlauhawmna chu i tihtlem thei a ni.

ADEM hmalam hun tur chu eng nge ni? Dam theih a ni em?

ADEM vei tam zawk chuan enkawl hnuah an dam kim vek emaw, an dam kim hnai tawh emaw a ni.. Inflammation a nasat lutuk chuan nunna atana hlauhawm tak a ni lo hle. I doctor chuan i dinhmun chu a tha berin a pe thei che a ni.

ADEM symptoms hi vawi khat chauh a awm tlangpui , mahse a chhan bulpui (MOGAD ang chi) a zirin a lo lang leh thei. ADEM hi enkawl a nih chuan a reh tlangpui a, mahse a natna lan chhuah dan chu a lo lang leh thei a ni. Mi tam zawk chuan dam chhung pangngai an nei a.

Engtikah nge Doctor ka hmuh ang?

ADEM ang chi symptoms i neih chuan, a bik takin infection hnuah , doctor pan ngei ngei tur a ni. A hmaa hriat chhuah a nih chuan enkawl tan thuai theih a ni.

Doctor zawh tur zawhna pawimawh

ADEM i vei nia hriat i nih chuan i doctor hnenah heng zawhnate hi i zawt mai thei:

• Engtin nge test atan ka inbuatsaih ang?
• Eng ang enkawlna nge i rawt?
• Enkawlna hian eng side effect nge a neih?
• Enkawlna hnuah pawh ka natna lan chhuah dan hi a la awm reng dawn em?

Kea kal theih loh, mitdel, emaw, sawifiah loha seizure neih ang chi symptoms i neih nghal chuan lungkham leh hlauhna i neih hi thil pangngai a ni. I medical team chuan hei hi i hmachhawn theih nan an pui ang che. Enkawlna thenkhatah chuan ni engemaw zat emaw, darkar engemaw zat emaw pawh a ngai thei. Hemi chhung hian lehkhabu chhiar la, i rilru ti hahdam thei thil ti rawh. Hei hi mi tam zawk tan chuan vawi khat thil thleng a ni tih hre reng ang che, mahse a thleng leh thei.

Thu tawite hriat reng tur

• ADEM hi thluak leh ruhro a inflammation nghal mai a ni.
• Hei hi a tlem hle a, natna hrik kai hnuah a thleng fo bawk.
• Kan taksa hriselna (immune system) ngeiin nervous system a rawn beih palh hian hetiang hi a thleng thin niin an ngai.
• A lan chhuah dan a inang lo va, khawsik, lu na , rilru hahna, mit lama harsatna, leh kal harsa te pawh a tel thei.
• MRI leh spinal fluid test hmanga hriat theih a ni ber.
• Steroid, IVIG, leh plasma exchange te ang chi enkawlna a awm bawk.
• Mi tam zawk chu an dam tha hle a, mahse a dam kim theih nan thla engemaw zat a ngai thei.
• Inven dan tur bik awm lo mah se, hri kai laka inven a pawimawh hle.

He thu hi i tanpui theih ka beisei. Zawhna dang i neih chuan doctor biak theihnghilh suh.