Acute Fatty Liver of Pregnancy (AFLP): Hei hi a pawi hle a, i fimkhur ang u!

Naupai lai hian a chang chuan beisei loh hriselna lama harsatna a awm thei tih i hria em? Vawiin hian beisei loh deuh pawh ni se, hriat hlawh tak, natna khirh tak tak awm thei chungchang kan sawi dawn a ni. Mi tam zawkah hetiang hi thleng lo mah se, a thleng a nih chuan enkawl vat a ngai a ni.

Naupai laiin he fatty liver disease (AFLP) an tih hi eng nge ni?

A awlsam zawngin Acute Fatty Liver of Pregnancy (AFLP) hi a awm lo hle a, mahse a na hle. Hei hi naupai laiin i liver a thau lutuk a nih chuan a ni. Hei hian liver failure leh nunna atana hlauhawm harsatna dang a thlen thei a ni. Dik tak chuan, medical emergency anga ngaih a ni . Hetiang a nih chuan a tha ber chu a rang thei ang bera naute hrin hi a ni.

AFLP hi engtiang chiahin nge a hluar?

Ngaihtuah buai suh, hei hi a tam vak lo. Hetiang dinhmun AFLP an tih hi a takah chuan a tlem hle. Kum khatah naupai 10,000 atanga 20,000 zinga pakhat chauh a nghawng niin an sawi. Chuvangin i hmuh fo thin thil a ni lo.

AFLP natna lan chhuah dante chu engte nge ni? (Hengte hi fimkhur rawh)

AFLP hi naupai kum thumna tawp lam – kar 36 vel – atanga tan a ni tlangpui a, a tam ber chu hmuhchhuah a ni. Mahse, a chang chuan a hmain a thleng thei a, naute pian thlengin a thleng thei bawk.

Hetiang dinhmunah hian chhinchhiahna thenkhat hmuh tur a awm a:

• Nausea leh vomiting: Naupai laiin hei hi thil pangngai angin lang mahse, a chang chuan AFLP symptom a ni thei.
• Pum natna: He natna hi a bik takin pum dinglam chunglam ah a awm thin.
• Chauhna nasa tak: Chauhna mai ni lovin, hah lutuk tih hriatna.
• Taksa lama lungawi lohna hriatna: Taksa lama lungawi lohna, natna i nei ang maia hriatna.
• Anorexia: Ei duhna zawng zawng hloh.
• Tuihal lutuk tih hriat : Tui engzat pawh in la, a tling lo ang maiin a la awm reng.
• Jaundice: I vun leh i mit var te chu a sen vek thin. Hei hi chhinchhiahna chiang tak a ni.
• Buaina emaw, ngaihtuahna fim thei lo emaw: Thil ngaihtuah harsa, rilru hahdam lo.

AFLP natna lan chhuah dan hi damdawi lam natna dang nen pawh a inang thei tih hre reng ang che. Chuvangin naupai laiin symptom danglam tak tak i neih apiang chu i doctor nen inbiakna neih a pawimawh hle. AFLP hi medical emergency a ni a, enkawl vat a ngai a ni.

Engvangin nge he AFLP hi a lo awm? Eng nge a chhan?

Researcher te hian AFLP hi eng nge a thlen tih chiang takin an la hre lo. Kan liver hnathawh ber pakhat chu fatty acids tihchhiat hi a ni. AFLP-ah chuan liver-in heng fatty acids a tihchhiat theihnaah harsatna a awm a, chu chuan liver-ah thau tam lutuk a awm khawm thin. Chu thau chu liver chhungah a tang lut a, chu chuan liver hnathawh dan pangngai a tibuai a ni. Hei hi enkawl loh chuan nunna atana hlauhawm tak a ni thei.

Genetic link a awm em? (LCHAD tlakchhamna) .

Zirna thenkhatah chuan AFLP hian genetic influence a nei thei tih hmuhchhuah a ni . Chu chu, enzyme tlakchhamna , long-chain 3-hydroxyacyl-CoA dehydrogenase (LCHAD) tlakchhamna avanga lo awm a ni thei tihna a ni.

He (LCHAD) tlakchhamna hi a awm lo hle a, (autosomal recessive) disorder . A awlsam zawngin, nautein hei hi a rochun theih nân, nu leh pa pahnihte chuan a tâna gene inzawm chu an dawng tûr a ni. Naute (LCHAD) tlakchhamna nei chuan fatty acids a metabolize tha thei lo. Tichuan heng fatty acids te hi nausen (placenta) kaltlangin nu thisenah an lut ta a ni. Hei hian nu thin (liver)-ah thau a khawlkhawm thei a ni. Naute taksa metabolism inthlak danglamna hian nu chu engtin nge a nghawng tih hi han ngaihtuah teh!

AFLP vei theihna tur risk factors te chu engte nge ni?

Tunah chuan he natna, AFLP tia koh hi genetic a ni thei tih kan hre ta. Chu chu nu leh pa atanga rochun theih a ni tihna a ni. Chu bakah, risk factor dang engemaw zat a awm bawk:

• Hei hi i naupai hmasak ber a nih chuan.
• Twins emaw a aia tam emaw i beisei a nih chuan.
• Mipa naupang i beisei a nih chuan.
• Diabetes i neih chuan.
• Naupai lai intrahepatic cholestasis i neih chuan.
• Preeclampsia i neih chuan.
• I thau lutuk a nih chuan.

Mahse, heng risk factor zawng zawng hi awm mahse, i doctor chuan AFLP i vei dawn leh dawn loh a sawi thei lo. Tin, i sawi lawk theih leh i ven theih thil a ni lo. Chu chu a ni a, tlem chuan a ti buai zual hle.

AFLP avanga harsatna awm thei te chu engte nge ni? (Hei hi a hlauhawm thei)

Naupai laiin acute fatty liver disease (AFLP) hi thihna thlen thei a ni . Nang leh i naute hi harsatna hrang hrang tawk thei turin in awm a ni. Chung zinga ṭhenkhat chu:

• Liver a tha lo.
• Kidney tha lo a awm.
• Lung failure a awm.
• Kaichhawng.
• Thisen chhuak.

Heng thute hriat hi a hlauhawm khawp mai, a ni lawm ni? Chuvang chuan he dinhmun hi hriat chian a pawimawh hle.

AFLP dinhmun hi engtin nge kan hriat theih ang?

AFLP hian organ dysfunction a thlen theih avangin, .Natna hi hriat hmasak a, enkawl tan vat a pawimawh hle. Diagnosis dik ber chu liver biopsy a ni . Hei hi i doctor-in i liver tissue chu microscope hmanga a enfiahna hmun a ni. Mahse, naupai lai hian hei hi tih a him lo fo. Chuvangin, i doctor hian i symptoms leh health history a zirin AFLP hi a hre thei fo thin.

Thisen test hian eng nge a zawn?

I doctor chuan AFLP a awm leh awm loh enfiah turin thisen test a ti ang. A châng chuan i doctor chuan liver function blood test result a zirin AFLP a ringhlel thei . Heng test-ah hian hetiang hi a lang fo thin:

• Liver enzymes a sang hle.
• I thisen zam (blotting process) lama harsatna awm.
• Thisenah ammonia, uric acid leh protein te a sang chho zel.
• Thisen sugar level hniam.
• Kidney chhiatna chhinchhiahna.

Test dang pawh a awm

I natna hriat chian nân, i doctor chuan ultrasound scan emaw, CT scan emaw a ti thei ang . Chungte chuan liver thlalak chipchiar tak a pe thei a ni.

AFLP hi engtin nge enkawl a nih? (Enkawlna rang a pawimawh!)

Nunna atana hlauhawm harsatna i tawh loh nân, i doctor chuan i naute chu a rang thei ang bera hrin tûrin a rawt ang che . Naute leh nausen (placenta) lakchhuah a nih hnuah chuan i thin (liver) chu zawi zawiin a lo harh tan ang. Hei hi he natna enkawlna ber leh awmchhun a ni.

AFLP ka vei theihna tur tihtlem nan ka tih theih tur a awm em?

Hei hi mi tam takin harsatna an neih a ni. AFLP hi a awm lo hle. Tin, a venna tur emaw, hriat lawk tur emaw chuan engmah tih theih a awm lo . Hei hi he natna vanduaithlak tak a ni.

AFLP ka neih chuan eng nge thleng ang?

AFLP i neih chuan i naute chu i hrin nghal tur a ni . Nau neih hnu ni 10 vel chhungin i liver function chu a normal leh tan ang. I liver test result a normal leh hma loh chuan damdawi in doctor-te’n an enkawl che a ngai dawn a ni.

AFLP vei leh theihna tur i risk chu eng nge ni tih chiang takin sawi theih a ni lo. I doctor chuan AFLP lo awm chhan ni thei tur fatty acids-ah hian thil danglam a awm em tih enfiah turin genetic test neih a rawt thei ang. Nakin lawkah nau i pai leh a nih chuan nu leh nausen damdawi lama mithiamte’n i naupai chu an enfiah tir tur a ni tih an fuih thei bawk .

Naute chu eng thil nge a tihsual?

Nu chunga natna nasat dan hian naute a nghawng dan a hril tlangpui. Nausen thenkhat chu nonketotic hypoglycemia (amino acids dik taka process theih lohna) an tih natna an vei thei a ni. Mi dangte chuan dilated cardiomyopathy (thinlung ruh chak lo) emaw neuropathy (nerve chhiatna) ang chi natna an nei thei bawk. Mahse, a tam zawkah chuan naute tana hlauhawmna chu nu tana hlauhawmna aiin a tlem zawk.

Engtik hunah nge Doctor ka hmuh ang?

Naupai lai hian i medical history kimchang i doctor hnenah i hrilh a, i symptoms i neih apiang hriattir a pawimawh bawk. Rinawm taka awm hian i mamawh damdawi lam enkawlna tha ber i hmu thei ang.

Naupai laiin a hnuaia symptoms te hi i neih chuan doctor pan nghal rawh :

• Abdominal emaw pelvic pain a reh lo.
• Chauhna nasa tak emaw malaise emaw.
• Nausea leh luak chhuak reng reng.
• Lu na, a reh lovang.

Hengte hi naupai chhinchhiahna pangngai a ni thei a, mahse thil pawi tak chhinchhiahna a ni thei bawk. Chuvangin rinhlelhna nei suh.

Doctor hnenah eng zawhna nge ka zawh ang?

Ngaihtuah teh, i doctor-in AFLP i nei tih a hrilh che a nih chuan... zawhna tam tak i neih hi thil pangngai a ni. Zawhna hrang hrang i inzawt duh mai thei:

• "Doctor, tunah hian naute hi ka hrin a ngai em?"
• "Ka nunna hi a hlauhawm em?"
• "Ka naute nunna hi a hlauhawm em?"
• "He AFLP dinhmun hi a ṭha chho dawn em ni?"
• "Eng ang enkawlna nge ka mamawh?"
• "Nau ka pai leh chuan hetiang hi a thleng leh dawn em ni?"
• "Engvangin nge hetiang thil hi ka chungah a lo thlen, doctor?"

Hetiang hian zawhna i ngaihtuah theih apiang zawt rawh. Engmah kha chelh tlat suh.

AFLP leh HELLP syndrome hi eng nge an danglamna?

HELLP syndrome ( Hemolysis, Elevated Liver Enzymes, and Low Platelet Count Syndrome)** hi naupai laiin a awm a, AFLP nen a inang a ni. Heng natna pahnih inthlauhna ber chu hun kal zelah thisen test result a inthlak dan hi a ni. AFLP hian thisen zam leh platelet level inthlak danglamna a huam tlangpui. Mahse, HELLP syndrome hian a tlangpuiin platelet count a tlahniam zauh zauh thin.

Tin, AFLP vei te hian:

• Liver function test-naah thil dik lo nasa tak a awm .
• Thisen sugar level a danglamna awm apiang.
• Kidney hnathawh dan dik lo chhinchhiahna.
• Test-naah bilirubin level sang (bilirubin hi bawlhhlawh a ni) a awm.
• Acidosis (thisen acidity tihpun).
• (Proteinuria) tih a ni.(Urine-a protein awm).
• Thluak hnathawh dan inthlak danglamna (e.g., ngaihtuahna fim tak neih theih lohna, buaina).

Naupai lai hian fatty liver neih hi thil pangngai a ni em?

Naupai lote tan pawh fatty liver disease hi a awm fo a, enkawl theih a ni. Mi tam zawk chuan an liver-ah thau engemaw zat an nei a. Mahse, he thau hi a lo punkhawm chuan thin (liver) a tichhe thei a ni. Hei hi naupai lai hian a hlauhawm zual hle , a chhan chu liver hi taksain toxins a paih chhuah dan a nih vang a ni. I thin (or i naute thin) hian hna a thawk tha lo a nih chuan i thisenah thil tha lo a lo pungkhawm thei a ni.

A tawp berah chuan hei hi ka sawi tur che u a ni (Take-Home Message) .

AFLP, a nih loh leh naupai laia acute fatty liver disease hi a awm lo hle a, mahse a na hle. A dang thei lo va, sawi lawk theih a ni lo. Hei hian i hriselna chanchin leh i naupai chhunga i natna lan chhuah dan danglam tak takte chu i doctor nen inbiakna neih a pawimawh tihna a ni. Heng sawihonate hian i doctor chu harsatna awm thei turte hriatchhuahna kawngah a pui ang a, i mamawh damdawi lam enkawlna pawh a pe ang che.

Hlauthawng suh, mahse fimkhur rawh . I taksa kha ngaihven rawh. Thil danglam emaw, danglam emaw i hriat chuan damdawi lam thurawn zawng nghal rawh. A pawimawh ber chu nang leh i naute hrisel taka awm hi a ni.

` Naupai laiin thin thau, AFLP, naupai harsatna, thin natna, jaundice, nau neih, LCHAD tlakchhamna