Alzheimer’s Disease hi thlahtu natna a ni em? Eng nge a nih chiang takin i zawng chhuak ang u.

I chhungkuaa mi tu emaw, i nu emaw, i pa emaw, i pi emaw, i pi emaw, Alzheimer natna vei an awm em? Chutiang thil a lo thlen chuan hlauhna leh lungkhamna nasa tak neiin, "Aw, he natna hi kei pawhin ka vei dawn em ni?", "Hei hi chhungkuaa kal zel thil a ni em?" Scientist-te chuan Alzheimer natna thlen chhan dik tak hi hriat tumin an la bei mek a ni. Mahse thil pakhat a chiang a, chu chu he natna hian kan genes nen inzawmna a nei tih hi a ni. Chuvangin vawiin hian Alzheimer natna leh kan genes inzawmna chungchang hi han sawi ila.

I en hmasa ang u, heng genes te hi eng nge ni?

A awlsam zawngin sawi ila, genes hi kan taksa siamtu leh thununtu blueprints a ni. In sak hmaa blueprint i siam ang bawkin. I mit rawng leh sam rawng hian natna thenkhat i vei theihna tur a tichiang mai ni lovin, natna thenkhat i vei theihna tur a tichiang bawk.

Heng genes te hi kan nu leh pa hnen atangin kan dawng thin. Kan taksa cell chhunga chromosome an tih thilah te dahkhawm a ni. Mi hrisel chuan heng chromosome pahnih hi 23 a nei a, a vaiin 46 a nei a ni. A tlangpuiin pair tin atangin pakhat, kan nu hnen atangin pakhat leh kan pa hnen atangin pakhat kan dawng thin. Chuvangin chutiang chuan kan nu leh pa mizia kan hmu thin.

Late-Onset Alzheimer’s leh genes te a ni

Alzheimer natna chungchang sawi dawn chuan chi hnih a awm a. Pakhat chu a tlangpui ber a ni a, kum 65 hnuah a awm tlangpui a, hei hi Late-Onset Alzheimer’s an ti.

Zirchiangtute chuan he Alzheimer natna chi hrang hrang vei theihna tipungtu gene an hmuchhuak a. Kan chromosome 19-ah a awm a, he gene hi APOE gene an ti a. He APOE gene hi chi hrang hrang a awm a. Chung zingah chuan APOE4 tih variant nei chuan midang aiin Alzheimer natna vei theihna a nei sang deuh hlek a ni. Hei hi khawvel hmun hrang hranga zirchianna tam takin a nemnghet tawh a ni.

Early-Onset Alzheimer’s chungchang hi han sawi ila

Hei hi Alzheimer natna chi dang a ni. A tlem hle. Chutiang a nih chuan, kum naupan lai aṭangin a lan chhuahna a lang a, chu chu kum 30, 40, a nih loh leh kum 50-ah te a ni . Chhungkaw pakhata mi engemawzat a nghawng fo avangin early-onset familiar Alzheimer’s disease an ti bawk.

Chutiang chhungkaw DNA enfiahtu zirchiangtute chuan chromosome 1, 14, leh 21-a gene-ah hian inthlak danglamna engemaw zat an nei tih an hmuchhuak a, heng gene inthlak danglamna te hi an naupan lai atanga he natna hi an neih chhan a ni.

Down syndrome leh Alzheimer natna te a ni

Hetah hian chromosome 21 chungchang chiang takin kan sawi a ngai a, Down syndrome tih hi i hre tawh mai thei. Mi pangngai aiin chromosome 21 copy extra an nei a ni. Mak tak maiin Down syndrome vei te hi an upat deuh deuh chuan an zinga tam tak chuan Alzheimer natna an vei thin. An thluak cell-ah pawh Alzheimer vei te zingah chhiatna hmuh tur ang chiah hi a lang. Scientist-te chuan heng dinhmun pahnih inzawmna hi an la zirchiang mek a ni.

A hnuaia table hian heng Alzheimer’s chi hnih hi a hrilhfiah belh thei che a ni.

Alzheimer natna hi genetic testing neih a ni em?

Hei hi mi tam takin zawhna an neih a ni. Ni e, thisen sample hian eng APOE gene variant nge i neih tih a hrilh thei che a ni. Mahse chu test result chuan Alzheimer’s i vei dawn nge dawn lo tih a hril hauh lo. Chuvangin heng test te hi research atan an hmang tam ber a ni.

Doctor-te chuan Alzheimer natna lo chhuak tlai tak a awm leh awm loh chuan genetic test neih an rawt lo tlangpui.A chhan chu, a result hian a tul lo taka lungkhamna leh lungngaihna a thlen a rinawm. Ngaihtuah teh, APOE4 gene i nei tih i hriat chuan, chu natna chu i vei lo mai thei a, mahse hlauthawng takin i nung reng ang. Chu chu thil tha a ni lo.

Mahse, i chhungkaw member engemaw zatin kum naupan lai atanga he natna hi an vei tawh a, chutiang bawka natna lanchhuahna i neih chuan i doctor chuan he test chi hi Alzheimer’s natna lo awm tan tirh atanga finfiah turin a rawt thei ang. Mahse, thil tam takah chuan doctor chuan Alzheimer natna hi genetic testing tel lovin a hmu thei tih hre reng ang che.

Heng genes chungchanga zirchianna atang hian eng hlawkna nge kan hmuh?

Scientist-te chuan Alzheimer natnaah hian gene tam tak a inrawlh mai thei niin an ngai. Heng genes te hi kan hmuh hian nakin lawkah hlawkna ropui tak tak engemaw zat min pe dawn a ni.

• Natna hriatthiamna tha zawk: He zirchianna hian mi thenkhatin he natna hi an vei chhan leh mi hrang hrangin kawng hrang hranga a nghawng chhan hriatthiamna min pe a ni.
• Risk sang tak neite hriatchhuah: Natna kai theihna sang tak nei mite chu hriat hmasak an nih chuan natna laka invenna tur thurawn leh enkawlna tul ang ang pek theih an ni.
• Enkawlna thar siam theih a ni: Eng gene nge natna thlentu tih chiang taka hriat hian zirchiangtute tan chuan anmahni beitu damdawi thar, tangkai tak tak hmuh a awlsam phah a ni.

Chuvangin, genes hi Alzheimer’s tih ang chi puzzle buaithlak tak zinga pakhat chauh a ni. Thil tam takin a nghawng a, chu chu kan nunphung te, kan ei leh in te, leh boruak nghawng te hi a ni.