Doctor-te’n nangmah emaw, i hnaih ber emaw cancer vei an nih thu an hriat chuan, enkawl dan tur chungchangah pawh buai leh hlauhna pawh a awm fo. Vawiin hian damdawi danglam deuh Avelumab tih kan sawi dawn a, chu chu cancer chi hrang hrang enkawlna atana hman a ni. He damdawi chungchanga thil awm dan leh hriat tur awmte chu awlsam leh chiang takin sawi ila.
He damdawi Avelumab an tih hi eng nge ni?
A awlsam zawngin Avelumab (brand name: BAVENCIO) hi vaccine a ni a, damdawi chi khat , monoclonal antibodies tih hming pu a ni. Kan taksa ngeiin a taksa a natna dotu (immune system) a puitu sipai trained ang maiin han ngaihtuah teh. He damdawi hian a tih chu kan taksa hriselna (immune system) hian cancer cell a hriat theih nan a pui a, a bei a, a tichhia a ni.
He damdawi hi cancer chi thum enkawlna atan hman a ni ber a:
- Merkel cell carcinoma: Hei hi vun cancer chi khat, a tlem hle a, mahse a darh chak hle.
- Renal cell cancer: Hei hi cancer chi khat, kal (kidney)-a awm thin a ni.
- Urothelial cancer: Cancer chi khat, zunthlum emaw, zun kawng hmun dangah emaw a awm.
Hei bakah hian i doctor hian damdawi lam harsatna dang atan pawh he damdawi hi a pe thei bawk. Hemi chungchanga zawhna i neih chuan doctor zawt la.
Enkawlna i tan hmaa i doctor hnena i hrilh tur thilte
Hei hi a pawimawh hle. Avelumab hmanga enkawlna i tan hmain i hriselna chanchin kimchang doctor hnenah i hrilh hmasak phawt a pawimawh hle. Engmah thup suh. A hnuaia natna i neih chuan doctor hnenah hrilh ngei ang che.
- Autoimmune disease i neih chuan: A awlsam zawngin sawi ila, hei hi immune system-in taksa cell hrisel tak takte a beih nana natna a ni. Entirnan, Crohn natna, ulcerative colitis, emaw lupus ang chi natna te.
- Stem cell transplant i neih tawh emaw, neih i tum emaw a nih chuan: a bik takin allogeneic stem cell transplant i neih chuan.
- Lung natna, thisen sang, emaw thisen cholesterol sang emaw i neih chuan.
- Organ transplant history a awm chuan.
- Nervous system nena inzawm natna i neih chuan: Entirnan, `myasthenia gravis` emaw `Guillain-Barre syndrome` ang chi natna.
- Avelumab emaw damdawi dang emaw, ei tur emaw, dye dang emaw allergy i neih tawh chuan.
- Naupai i nih chuan, naupai tum i nih chuan, nau hnute i pe a nih chuan: Hei hi a pawimawh hle.
Engtin nge he damdawi hi ka pek theih ang che?
Hei hi damdawi in lama hruai theih a ni lo. Avelumab hi injection a ni a, i taksaah zawi zawiin vein (infusion into a vein) kaltlangin pek thin a ni . Saline pek che ang mai a ni. He enkawlna hi damdawi in emaw, clinic emaw-ah pek a ni a, doctor emaw, nursing staff trained emaw enkawlna hnuaiah pek a ni .
Treatment session apiangin he damdawi chungchangah hian special information leaflet (MedGuide) pek i ni ang. A hun apiangah ngun taka chhiar leh hriatthiam a pawimawh.
Damdawi i ei tam lutuk chuan engtin nge ni ang? (A tam lutuk) .
Hei hi damdawi inah pek a nih avangin hetiang thil thleng theihna chance hi a tlem hle. Amaherawhchu, he damdawi hi i ei tam lutuk nia i hriat chuan damdawi lam thawktute hnenah hriattir nghal rawh. Chutiang a nih loh chuan Colombo National Hospital-a National Poisons Information Center call la, a nih loh leh damdawi in hnai ber Emergency Treatment Unit (ETU)-ah kal rawh.
Enkawl laia ngaihtuah tur thil
I doctor chuan i enkawlna chhung zawngin uluk takin a lo en reng ang che a, i enkawlnain a nghawng dan leh a nghawng tha lo eng pawh enfiah turin thisen test neih fo a ngai mai thei bawk.
Naupai lai leh nau hnute pek lai hian fimkhur hle ang che!
Hei hi thil pawimawh tak a ni.
- He damdawi i ei lai leh enkawlna chawlhsan hnu thla khat tal naupai vek loh tur. Hemi chungchangah hian hmeichhiate hi fimkhur zual tur a ni, he damdawi hian nausen piang lai tan harsatna nasa tak a thlen thei a ni.
- Tin, he damdawi hi i ei lai leh i ei hnuhnung ber atanga thla khat tal chu naute hnute pek loh tur a ni.
Hemi chungchanga zawhna i neih chuan i doctor nen inbiakna neih hreh suh.
He damdawi hian eng side effect nge a neih theih?
Damdawi dang ang bawkin Avelumab hian side effect a nei thei a ni. Mahse, mi zawng zawngin an hmu vek lo. Side effect thenkhat chu a pawi thei hle a, chuvangin fimkhur a pawimawh hle. Hengte hi a hnuaia table-ah hian chiang takin i hrethiam ang u.
| Side effect chi hrang hrang | Ziarang |
|---|---|
| Side effect na tak tak, i doctor emaw nursing staff emaw hnenah hriattir nghal tur a ni | |
| Allergic reaction leh immune system lama harsatna nei te | Thâwk harsa, rilru thawm, taksa na, khawsik, khawsik hriat, vun sen, blisters (ka chhungah pawh a awm thei), ruh na, hah lutuk. |
| Digestive system lama harsatna awm thei | Pum na, luak chhuak na tak (thisen emaw tui emaw), chaw ei kham, ek dum emaw tarry emaw, luak chhuak, luak chhuak. |
| Kidney chhiatna chhinchhiahna | Zun chhuah tlem emaw inthlak danglam emaw, zun harsatna, ke emaw ke ruh emaw a hring. |
| Liver chhiatna chhinchhiahna | Zun dum emaw, sen emaw, mit emaw vun emaw a sen, pum dinglam chunglam na, ei duh lohna, leh rilru hah lutuk. |
| Symptom na tak dang a awm bawk | Hnung na, mit a danglam, thinlung thawk chak emaw, mumal lo emaw, muhil, thawk hah lutuk, taksa rihna tlahniam, sam tlakchham, riltam lutuk emaw tuihal lutuk emaw. |
| Side effects nasat loh tlangpui, mahse a awm reng chuan doctor hnenah hriattir tur a ni | |
| Hliam tenau te | Lu na, ruh na, ruh na, chaw ei chak lohna. |
He list-ah hian side effect awm thei zawng zawng a tel lo. Thil danglam tak i tawn chuan i doctor hnenah hrilh rawh.
Take-Home Thuchah a ni
- Avelumab hi kan taksa hriselna tichaktu vaccine bik a ni a, cancer chi hrang hrang tan pek a ni.
- Enkawl i tan hmain i damdawi lam dinhmun zawng zawng, i damdawi ei zawng zawng leh allergy i neih zawng zawngte chu engmah thup lovin doctor hnenah hrilh hmasa phawt ang che.
- He damdawi hi ei lai leh ei zawh hnu thla khat tal naupai leh hnute pek loh hi a pawimawh tak zet a ni.
- Thâwk harsa, vun hring, ril\am na tak, mit sen ang chi side effect na tak i neih chuan doctor pan nghal rawh.
- Doctor appointment te chu bawhchhiat loh tur a ni. I siam theih loh chuan hriattir lawk la, appointment dang siam leh rawh.
- Zawhna emaw, ngaihtuahna emaw i neih apiang chu i doctor nen zalen taka inbiakna neih hi i dikna a ni.
👩🏽 ⚕️ Zawhna dang (FAQ)
💬 Felodipine / Plendil tablet hi eng atan nge hman?
Hei hi khawvela thisen sang pill (Calcium Channel Blocker - CCB) tha tak leh chak tak a ni a, ‘Severe high blood pressure’ control nana duan a ni! He pill hi a hip zawi zawia (Extended-release) a siam a, chuvangin nitin (darkar 24) chhungin pressure a hniam reng a ni.
💬 Engtin nge he thisen sang pill (Felodipine) ei hian kan thisen sang a tihhniam nghal?
Thisen kalna kawngkhar (contract/contract) tur leh pressure a san theih nan chuan ‘Calcium’ particle te chu thisen kalna kawng ah a lut tur a ni! He pill hi thisenah a luh meuh chuan chu thisen kalna kawng chhunga calcium gate (L-type calcium channels) zawng zawng chu 100% in a block/closed vek a, a lock vek bawk. Calcium a luh loh avangin thisen kalna chu a inzawm lo va, a lo chhuak nasa hle (Vasodilation). Tichuan, thisen chu lui ang maiin awlsam takin a luang a, pressure a tlahniam bawk.
💬 He damdawi (Felodipine) ei hian eng side effects ti thinrim tak nge a neih? Engvangin nge grapefruit ei loh tur an tih?
Buaina lian ber chu he pill i ei lai hian ‘Grapefruit/Grapefruit juice (a type of sweet orange)’ i in ngai lo tur a ni! I in chuan damdawi taksa chhunga a luh dan chu a pangngai lo takin 100% in a pung ang a, a tawpah chuan pressure a tlahniam thei a, i tlu thei bawk (CYP3A4 Inhibition)! Side effect dang tibuaitu ber chu hei hian ‘Swelling of the ankles/legs (Peripheral Edema)’ leh heartbeat/redness of the chest (Flushing) rang tak a thlen ngei ang.
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