Ni engemaw zat chhunga khawsik emaw, flu emaw hi engtin nge a bo theih tih i ngaihtuah ngai em? A nih loh leh naupan laia vaccine pek hian natna thenkhat lakah engtin nge dam chhung atan min humhim? Heng zawng zawng hnung lamah hian kan taksa chhungah sipai tenau tak, mahse thiltithei tak tak, mit hmuh theih loh a awm a. Vawiin hian chu sipaiah chuan sipai bik tak chungchang kan sawi dawn a ni. Chu chu B cells te an ni .
A awlsam zawngin, heng B cell te hi tute nge ni?
B cell hi kan taksaa thisen var chi khat a ni. A dik tak chuan cell chi khat bik an ni a, thisen var pawl, lymphocytes an tih zinga mi an ni. Kan taksa hi ram lian tak a ni tih han ngaihtuah teh. Tichuan kan immune system hi chu ram defence army a ni. He sipaiah hian brigade hrang hrang an awm a. Chutiang bawkin kan immune system-ah hian cell chi hrang hrang a awm a.
Chung zingah chuan B cell te hian mawhphurhna pawimawh tak an nei a. Chu chu kan taksaa lut virus leh bacteria ang chi hmelma te do turin ralthuam an siam chhuak tihna a ni. Damdawi lamah chuan heng ralthuamte hi antibodies tiin kan sawi thin. Heng proteins antibodies an tih te hi natna thlentu hrik kan taksaa lut te tihchhiat nan kan hmang thin.
B cells bakah hian kan immune system member pawimawh dang chu T cells hi a ni. B cell te hi ralthuam siamna factory ang an nih laiin, T cell te erawh chu hmêlma tihchhiat emaw, indona kaihruai emaw tura indona hmuna kal nghal mai sipai hotu ang an ni. Hêng pahnihte hian kan thawhhona chuan natna lakah min vênghim a ni.
B cell hi chi hnih lian tak a awm a.
Kan security force-ah ang bawkin B cell pawl hrang hrang, hna hrang hrang thawktu an awm a. A bik takin chi hnih a awm.
| B cell chi hrang hrang | Hna thawh mekte chu |
|---|---|
| Plasma Cells te hi a awm a | Hengte hi "ralthuam siamtute" an ni. He natna hrik taksaa a luh chuan heng cell te hian a do turin antibody tam tak an siam chhuak thin. Plasma cell pakhat hian second khatah antibody 2,000 vel a siam thei tih i hria em? Chu chu heng mite hi an efficient zia chu a ni. Mahse an dam chhung hi a tawi deuh. |
| Hriatrengna Cells te | Chungte chu "spies" emaw "archive keeper" emaw an ni. Heng cell-te hian an tih tur chu taksa chhunga hmêlma (germ) lut apiangte chipchiar taka hriat reng hi a ni. Chu chu taksaa virus lo lut tawh chu vawi khat a lo kir leh chuan heng memory cells te hian rang takin an hre chiang a, immune system hnenah an hriattir nghal a ni. Tichuan plasma cell-te chuan rang takin antibody mamawh chu an siam thei a, chu hmelma chu natna a thlen hmain an tichhia thei a ni. Kan vaccine kan pek che hian hna a thawk a, a chhan chu heng memory cells te hriatrengna a tichak a ni. |
Naupan lai khan measles i vei niin han ngaihtuah teh. A nih loh leh, measles laka vaccine pek i nih thu emaw. I taksaa memory B cells te hian measles virus hi an hre reng tha hle. Measles virus hian i taksaah luh a tum leh a nih chuan heng memory cell te hian an hmuh veleh an hre nghal a, sipaite hnenah signal an thawn nghal a ni. Chumi avang chuan measles i vei leh tawh lovang. Chu chu heng memory cells te thiltihtheihna mak tak hi a ni.
B cells hnathawh dan mak tak mai
Hriselna taksa chhunga natna hrik a luh hian B cell-te an thiltih dan hi a buaithlak hle a, mak tak mai a ni. Step awlsam tlemte hmangin i hrethiam ang u.
1. Hmelma hriat chian: Pakhatnaah chuan kan immune system-a "guard cell" (Antigen-presenting cell - APC) chuan kan taksaa hmelma (virus/bacteria) lo lut chu a man a. Hêng hmêlma chungchângah hian anmahni hriat theihna tûr chhinchhiahna bik a awm a. Antigen an ti a . Misual taksaa tattoo ang mai a ni. Guard cell hian he hmelma hi a man a, a chung lamah a antigen (tattoo) a lantir a ni. Mi zawng zawng hnenah "Hei hi rukru a ni" tih lantir ang mai a ni.
2. Sipai hotute hriattir: Hetianga hmêlma chhinchhiahna lantîr hi kan sipai hotu bik pakhat, chu chu ṭanpuitu T cell -in a hmu a ni. T cell hian hei hi a hmuh veleh a activate nghal a ni. Amah hi B cells te hnena thupek petu tur a ni.
3. B cell activation: T cell activated chu a kal a, a kaihhnawih B cell-ah a inzawm a, "indona atana inbuatsaih rawh" tih signal a thawn a ni. He signal a dawn hian B cell chu a inthen tan a, a copy (clone) sang tam tak a siam ta a ni.
4. Thiltihtheihna pahniha inthen: Hetianga B cell lo piang thenkhat chu plasma cell an lo ni ta a ni . A dang chu memory cell a lo ni ta a, nakin lawka indona atan a inpeih tawh bawk.
5. Antibody beihna: 1.1.Plasma cell an nih hnu chuan, hmêlma hmasa ber beih tûra siam bîk antibodies maktaduai tam tak an siam ṭan a ni. Heng antibodies te hi homing missile ang mai an ni. An kal a, taksa pum puiah hmelma te nen an inzawm a, an tichhia emaw, an inactivate emaw a ni. Hetiang hian natna atanga kan dam leh dan chu a ni.
Kan taksaah hian khawiah nge B cells siam chhuah?
Embryo anga kan nu pum chhunga kan awm hian thin (liver)-ah B cells a lo piang chhuak thin. Mahse kan pian hnu hian kan ruhroah B cells a lo piang chhuak ta a ni. Bone marrow hi kan ruh lian tak takte spongy part a ni. Heng B cells te hi chuta hematopoietic stem cells atanga siam chhuah an ni. An puitlin hnuah heng B cell te hi kan lymphatic system-a thil pawimawh tak, spleen leh lymph node-ah an kal a, duty-ah an report thin.
B cells hnathawh a tihbuai chuan eng nge thleng ang?
Kan immune system hian hna a thawk tha ngai lo. A châng chuan, B cell-te hnathawh dân inthlâk danglam chuan natna khirh tak a thlen thei a ni.
| Natna chi hrang hrang | Eng thil nge thleng tih leh entawn tur |
|---|---|
| Autoimmune Natna te | Hei hi dinhmun lungchhiatthlak tak a ni. Heta thil thleng hi kan B cell te hian "friend leh foe" an thliar hrang thei lo. Chu chu B cells te hian kan cell hrisel tak takte lakah antibody an siam tan tihna a ni. Keimahni sipai ngeiin min rawn bei ang mai a ni. Entirnan:
|
| Cancer natna vei te | A châng chuan B cell-a thil dik lo a awm avangin thunun theih lohvin an inṭhen ṭan ṭhin. Hetianga B cell pangngai lo tam tak awmkhawm hian cancer a thlen thei a ni. Entirnan:
|
Engtin nge i B cell level chu a normal em tih i hriat theih ang?
Puitling pakhatin thisen microliter khatah lymphocyte 1,000 leh 4,800 inkar a nei a. Heng lymphocyte zinga 10% leh 20% inkar hi B cell an ni.
I doctor-in thisen chhiar kimchang (CBC) test a tih chuan i taksaa lymphocyte awm zawng zawng chu a hriat theih phah a ni. Mahse, i B cells chungchang hriat tur i mamawh chuan specialized test i neih a ngai dawn a, chu chu lymphocyte profile tih a ni. Heng test result atang hian i doctor chauhvin i B cell level sang leh hniam leh a chhan leh a chhan chu a hre thei ang. Chuvangin i thisen test chungchangah harsatna i neih chuan i doctor nen inbia ngei ang che.
Engtin nge kan immune system leh B cell te hi kan tihchak theih ang?
Natural taka B cell count tihpunna tur hian thilmak tihdamna chiang tak a awm lo. Mahse, kan taksa hriselna zawng zawng hi hrisel leh chak taka kan vawn tlat chuan kan B cell te chu an hna dik tak thawk turin kan pui thei a ni. Chûngte chu i tân thil awlsam tak angin lang mah se, kan invennate chu a thawh tam lutuk loh nân a pawimawh hle.
- Vaccine rawt zawng zawng la rawh: Vaccine hi kan memory B cells te zirtirna tha ber a ni.
- Ei leh in inthlau tak ei rawh: Vitamin leh mineral tamna ei tur, thlai, thei, leh greens te pawh telh bawk ang che.
- Stress enkawl: Stress tam lutuk hian immune system a tichak lo. Meditation, exercise, leh hobby tih ang chi thil hmangin stress i tihziaawm thei a ni.
- Zu leh zu in loh tur: Hengte hian taksa hriselna (immune system) a tichhe nghal vek a ni.
- Mut tawk: Ni khata darkar 7-8 vel mut that hi taksa chakna (immune system) a lo that leh theih nan a pawimawh hle.
- Exercise neih fo: Kar khatah minute 150 tal exercise tlemte neih hi i hriselna atan a tha hle.
- Thianghlim rawh: Savun hmanga kut sil fo hian natna hrik duh loh darh tur a veng thei a ni.
B cells hi kan taksa chhunga mi huaisen te tak te, ngawi reng mahse thawk reng thin te an ni. An tel lo chuan antibody kan siam thei dawn lo. Antibodies tel lo chuan khawsik awlsam tak pawh hian nasa takin min ti na thei a ni. Chuvangin, heng kan venghimtu te te hi enkawl ila, kan taksa hriselna (immune system) te hi chak taka vawn reng kan tum vek ang u.
Take-Home Thuchah a ni
- B cells hi kan immune system-a thisen var chi khat bik a ni a, natna hrik do turin antibody a siam chhuak thin.
- B cell hi chi hnih a awm a, chungte chu plasma cell, tun dinhmuna indo thin leh memory cell, hmelma hre reng thin te an ni.
- Vaccine hian memory cells te tichakin hna a thawk a, chu chuan nakin lawkah chu natna chu kan vei loh nan min venghim a ni.
- B cells hnathawh that loh hian autoimmune diseases leh cancer te ang chi natna khirh tak tak a thlen thei a ni.
- Nunphung hrisel (ei leh in tha, mut, exercise, stress management) zawm hian kan taksa hriselna (immune system) pum pui chu kan tichak thei a ni.
- I thisen test emaw, immune system emaw chungchangah harsatna i neih chuan doctor rawn hmasa phawt ang che.
💬 Comments (0)
Comment a la awm lo. Hetah hian i comment hi a vawikhatna atan add rawh.
I comment kha add rawh