Asthma ang maiin thawk harsa i nei em? Chutiang hunah chuan doctor chuan inhaler hmang turin a ti che a ni mai thei. Beta-agonists hi chutiang inhaler-a awm damdawi chi khat bik a ni a, chu chuan kan thawk a ti awlsam hle. He hming hi a buaithlak deuh a, mahse hengte hnathawh hi a awlsam hle. Hemi chungchang hi chipchiar deuhin, awlsam takin han sawi ila.
A awlsam zawngin, beta-agonist chu eng nge ni?
Kan taksa chhunga cell awmte hi ‘switch’ emaw ‘button’ emaw tlemte nei angin han ngaihtuah teh. Damdawi lamah chuan heng receptor te hi kan ti a. Hetiang damdawi chi, beta-agonist tia koh hian kan lung leh taksa peng dangah heng ‘switch’ beta-receptor an tih te hi a on a ni.
He switch hi on a nih chuan lung chhunga thawkna kawng vel muscle te chu a relax ta a ni. Hei hian thawkna kawng a zim tawhte a hawng a, kan thawk pawh a awlsam phah hle. Chuvangin heng damdawi te hi ‘bronchodilators’ an ti bawk. Tin, heart rate tihsan nan an pui a, heart hnathawh pawh eng emaw chen tipung turin an pui bawk.
Beta-agonists chi hrang hrang lian ber ber a awm em?
Ni e, heng damdawi te hi kan taksaa beta-receptor chi hrang hrang a zirin chi thum ah then a ni bawk.
- Beta-1 agonists: Hengte hian kan thinlunga receptor te a nghawng ber a ni . Hetiang damdawi chi hian thinlung a ti chak a, thisen chu chak zawkin a pump thei bawk. Chuvang chuan doctor ten thinlung lam harsatna leh emergency thenkhatah an hmang thin.
- Beta-2 agonists: Hei hi hman tam ber chi a ni. Heng damdawi te hi, a bik takin inhaler hmanga pek te hian lung chhunga receptor te nen direct in an inzawm a, thawkna kawng chhunga thau te chu a ti hahdam a, thawk pawh a ti awlsam bawk. Asthma leh COPD (Chronic Obstructive Pulmonary Disease) ang chi natna enkawlna atan an pawimawh hle.
- Beta-3 agonists: Hengte hi damdawi class thar tak a ni. Tuna he class-a damdawi hman mek hian a bul berah chuan bladder-a taksa ruhte tih hahdamna hmangin hna a thawk a, zun tam ngaina a ti tlem a ni. Hei hian overactive bladder an tih natna enkawlna atan an hmang tihna a ni.
Beta-2 agonist chi hrang hrang a awm bawk.
Ni e, he beta-2 type hi thawk harsatna atana pek thin pawh hi hmun hnih ah then a ni. Hei hi i hriat a pawimawh hle.
| Damdawi chi hrang hrang | Hrilhfiahna |
|---|---|
| Beta-Agonists (SABA) te hi hun rei lote chhunga thawk thei an ni. | Chungte chu "rescue inhalers" an ti a. Asthma attack a nasat thut emaw, thawk harsatna i neih emaw chuan an hmang thin. Minute tlemte chhungin hna an thawk a, chhawmdawlna rang tak an pe bawk. |
| Hun rei tak chhunga Beta-Agonist (LABA) te . | Chûngte chu chhawmdawlna rang tak atân a ni lo. Nitin, a hun takah, natna lan chhuah dan control nan leh thawk harsatna ven nan an hmang thin. An nghawng chu darkar engemaw zat a daih. A tlangpuiin steroid (corticosteroid) damdawi nen an ei dun thin. |
He damdawi hian taksa chhungah engtin nge hna a thawh?
Hei hi hriatthiam dan tha ber chu kan taksain "fight-or-flight" a chhan dan ngaihtuah hi a ni. Hlauhawm tak i hmachhawn dawn tih han ngaihtuah teh. Chutih lai tak chuan i taksa chuan indo emaw, tlanbo emaw turin a inbuatsaih a.
Hetih lai hian thluak a\angin signal a lo chhuak a, chu chuan oxygen tam zawk la turin lung chhunga thawkna kawngte chu a tizau a, chu thisen oxygen tamna chu taksa peng hrang hrangah rang zawka thawn chhuah theih nan thinlung chakna a ti chak a ni.
Chutiang chiah chu beta-agonist damdawi hian artificial-in a ti thin. ‘Switch’ (receptor) dik tak an on a, taksa chu emergency hmachhawn ang maiin an chhang let thin. Chuvang chuan lung chhunga thau (muscles) te chu a relax a, thawk a awlsam phah hle.
Beta-agonist damdawi hman tam berte chu engte nge ni?
Beta-agonist damdawi chi hrang hrang doctor ten an pek thin a awm a. Entirna thenkhat chu hetiang hi a ni:
| Ruihhlo chi hrang hrang | Entirnan (ruihhlo hming) . |
|---|---|
| Hun rei lote chhunga thawk thei beta-2 (SABA) . | Salbutamol / Albuterol, Levalbuterol tih te hi a awm a |
| Hun rei tak chhunga thawk thei beta-2 (LABA) . | Formoterol, Salmeterol, Indacaterol te pawh a awm bawk |
| Beta-1 agonist a ni | Dobutamine, Norepinephrine hmanga tihdam theih a ni |
| Beta-3 agonist a ni | Mirabegron a ni |
He damdawi hian side effect a nei em?
Damdawi dang ang bawkin beta-agonists hian mi thenkhatah side effect a thlen thei a ni. Mahse, inhaler atana hman a nih chuan damdawi chu lungah a kal nghal a, chuvangin a side effect a na lo tlangpui. Mahse, mi thenkhat chuan hetiang hian an tawng mai thei:
- Lung natna chak tak (Tachycardia) .
- Thinlung thawk mumal lo (Arrhythmia) .
- Shakiness a ni
- Hlauhthawnna
- Lu na
- Muscle a ti na hle
- Thawmhnaw hak
A pawimawh ber chu heng side effects te hi i tawk a nih chuan, emaw, damdawi i hman hnua thil danglam tak i hriat chuan doctor nen inbia nghal rawh. A dose a siamrem thei a, damdawi dang a pe thei bawk che.
Engtikah nge Doctor i hmuh ang?
Doctor hmuh a pawimawh em emna dinhmun engemaw zat a awm.
- Duh lo, beisei loh side effect i neih chuan .
- I damdawi chu a hma angin a thawk tha lo nia i hriat chuan (entir nan, hahdamna i hmuh theih nan i inhaler hi a hma aia tam i hman a ngai a ni).
- I symptoms te chu a na zual zel a i control thei lo tih i hriat chuan .
Chutiang a nih chuan i doctor chuan i enkawlna ruahmanna chu a enfiah thei ang a, solution nuam leh tangkai ber a pe thei ang che.Damdawi ei kha bansan ngai suh la, doctor thurawn tel lovin a dose pawh thlak ngai suh. Side effect na tak i neih chuan damdawi in hnai ber Emergency Department (ETU) pan nghal rawh.
Take-Home Thuchah a ni
- Beta-agonists hi thawk awlsamna damdawi chi khat a ni a, thawkna lam natna, asthma leh COPD te enkawlna atan hman a ni ber.
- A chi hnih a awm a, chungte chu short-acting (SABA) a ni a, emergency-a chhanchhuahna rang tak a pe a, long-acting (LABA) hian hun rei tak chhung natna hi a thunun thei a ni.
- He damdawi hi doctor-in a sawi ang chiah hian hmang fo la, a pek zat chauh hmang rawh .
- Thinlung thawk chak leh kut khur ang chi side effects te chu fimkhur hle ang che. Harsatna i neih chuan doctor hnenah hriattir nghal rawh.
- I enkawlnain a thawk tha lo emaw, i natna lan chhuah dan a zual emaw nia i hriat chuan mahni inenkawl suh la, damdawi lam thurawn zawng rawh.
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