Asthma i nei em? I inhaler hi a tih angin i hmang a, damdawi dang i ei mai thei a, mahse i asthma symptoms chu a tha lo hle. I thawk hah fo a, i rilru a na a, i khuh fo a nih chuan asthma na tak atanga na tak i nei thei a ni. Hetiang enkawl dan thar, changkang tak, ‘Biologic Therapy’ tia koh hi chutiang asthma natna thunun harsa tak takte tan chuan hman a ni.
A awlsam zawngin, Biologic Therapy chu eng nge ni?
Hei hi tunlai, targeted treatment a ni a, asthma na tak enkawlna a ni. Inhaler pangngai hian hun eng emaw chen atan thawkna kawng a tizau a, thawk a ti awlsam a, biologic therapy erawh a thuk zawk a ni.
Ngaihtuah teh, asthma kan vei chhan ber chu taksa immune system hnathawh dang engemaw avanga thawkna kawngah inflammation a ni. Chuvangin heng biologic drugs te hian an tih chu taksa chhunga antibodies, cell emaw molecule bik te chu target a, chu inflammation thlentu leh an hnathawh tihtawp a ni. Hei vang hian Asthma hi basic level-ah control a ni.
He enkawlna hi kawng lian pahnihin pek a ni. Pakhat chu vun hnuaia injection (subcutaneous injection) angin a ni a, pakhat chu intravenous (IV infusion) infusion angin a ni.
A pawimawh ber chu hei hi stand-alone treatment a ni lo. I inhaler awmsa leh asthma damdawi dangte nen hman dun tur a ni.
He enkawlna hi tute tan nge a inhmeh?
Biologic therapy hi Asthma vei zawng zawng tan a ni lo. I doctor chuan he damdawi hi i tan a rawt hmain thil engemaw zat a ngaihtuah hmasa ang. A hnuaia table hian ngaihtuahna tha tak a pe ang che.
| Biologic Therapy atana refer theihna tur dinhmun | |
|---|---|
| Damdawi pek hmanga control theih loh | I inhaler leh damdawi dang i pek dik tak hmang chung pawha i asthma symptoms control loh chuan. |
| Thisen test result a ni | I thisenah Eosinophils (thisen var, lung chhunga inflammation thlentu) emaw IgE (allergy nena inzawm antibody) emaw level sang tak i neih chuan. |
| Natna tizual theitu | I asthma tichhuaktu chu eng nge ni tih i hriat a, pumpelh la, mahse symptoms a awm reng chuan. |
| Symptoms a awm fo thin | Zanlai pelh hnua khuh neia i thawh chuan, emaw, i rescue inhaler hi kar khatah vawi hnih aia tam i hman chuan. |
| Exacerbation a awm fo thin | Kum khatah vawi hnih aia tam corticosteroid pill ei a ngai emaw, ETU (Emergency Treatment Unit) pan a ngai emaw a nih chuan. |
| Damdawi inah dah a ni | Damdawi inah awm reng a ngai a, asthma vangin enkawlna i dawng a ngai a nih chuan. |
Asthma tan hian eng biologic drugs nge awm?
Tun thlenga biologic damdawi chi hrang hrang pawm tawh a awm a. An hnathawh dan chu a danglam deuh hlek a ni. I doctor chuan i asthma type leh thisen test result a zirin i tan damdawi tha ber a thlang ang.
| Damdawi hming | Function leh delivery dan tur | Side effect awm fo thin |
|---|---|---|
| Omalizumab (Xolair®) hmanga tihdam theih a ni. | Allergy avanga Asthma natna a enkawl. Kar 2-4 danah vun hnuaiah inject thin a ni. | Muscle na, ruh na, hah lutuk, injection na hmuna hring/na. |
| Mepolizumab (Nucala®) hmanga tihdam theih a ni. | Eosinophilic asthma a enkawl thin. Kar 4 danah vun hnuaiah inject thin a ni. | Lu na, hnungzang na, chak lohna, hah, injection na hmuna hring/na. |
| Reslizumab (Cinqair®) hmanga tihdam theih a ni. | Eosinophilic asthma a enkawl thin. Kar 4 danah thisenah (IV) pek thin a ni. | Thlarau na, taksa ruh na. |
| Benralizumab (Fasenra®) hmanga tihdam theih a ni. | Eosinophilic asthma a enkawl thin. Dose hmasa 3 hi kar 4 danah pek thin a ni a, chutah chuan kar 8 danah pek thin a ni. | Lu na, ril na. |
| Dupilumab (Dupixent®) hmanga enkawl a ni. | Eosinophilic asthma leh inflammation avanga natna dangte a enkawl. Kar 2 danah inject thin a ni. | Thlarau na, injection na hmuna hring/na, thisen var cell count a tipung. |
| A rilru a buai em em a, a rilru a hah em em bawk a. | Asthma na tak damdawi thar. Inflammation a tihziaawm. Kar 4 danah inject thin a ni. | Thlarau na, hnungzang na, ruh na. |
He enkawlna hian eng chen nge a daih?
Hei hi a tlangpuiin hun rei tak enkawlna a ni. He damdawi hian i tan a thawk tha em tih chiang taka hriat nan thla 4-6 tal a ngai thei. Chuvangin i enkawl danah dawhtheih a pawimawh.
Ka inhaler hi hman chhunzawm zel a ngai em?
Ni e, a dik ngei ang.Hei hi a pawimawh ber a ni. Biologic therapy i tan hnuah pawh i inhalers leh i doctor-in a pek damdawi dangte ei kha titawp ngai suh. Hun a kal zel a, i asthma chu i control tha a nih chuan i doctor chuan i inhaler dose tihtlem a tum mai thei. Mahse hei hi doctor thurawn hnuaiah chauh tih tur a ni.
He enkawlna hian eng hlawkna leh hlauhawmna nge a neih?
Enkawlna dang ang bawkin he damdawi hian hlawkna a neih bakah hlauhawmna tenau a nei bawk.
A thatna ber chu:
- Thluak kawng a inflammation a tihziaawm bakah asthma symptoms te pawh a control tha hle.
- Khawsik leh khuh fo te chu a tlahniam ang.
- A hma ang bawka thawhrim ngai lovin exercise i ti thei ang a, nitin hna i thawk zo thei bawk ang.
- Zanah i harh chhuah zat a tlahniam.
- ETU (Emergency Treatment Unit) -a kal tlem a ngaihna a tlahniam dawn a ni.
- Nunphung pawh a tha chho zel a ni.
Risk awm thei: 1.1.
- Allergy na tak: A tlem hle a, mi thenkhat chuan allergy na tak (anaphylaxis) an nei thei. Hei vang hian a hmasa ber atan damdawi in emaw clinic emaw-ah doctor enkawlna hnuaiah pek thin a ni.
- Parasitic infection awm theihna: Eosinophils tihziaawmna damdawi hian taksain parasite, a bik takin helminth a do theihna chu tlem a ti tlem thei a ni. Chuvangin i doctor chuan he enkawlna hi i tan hmain chu chu a ngaihtuah hmasa ang.
Pawimawh: Doctor thurawn tel lovin he damdawi hi eng thil vang pawha ei thut loh tur a ni. Chutianga i tih chuan i asthma symptoms chu a tizual thei a ni.
Doctor nen engtikah nge i inbiakna tur
A hnuaia thil thlengah hian doctor rawn la, hriattir ngei ngei tur a ni.
- Thla engemaw zat enkawl hnua asthma symptoms a ṭhat loh emaw, a nasat loh emaw chuan.
- Allergy symptom thar (e.g. vun rawng, vun hring) a lo lang a nih chuan.
- Enkawlna chungchanga zawhna emaw, ngaihtuahna emaw i neih chuan.
He enkawlna hi specialist doctor rawtna angin emaw, damdawi in (infusion center) specialized unit atang emaw, specialist doctor clinic atanga lak theih a ni. He enkawlna hi a man a to deuh thei. Mahse i doctor nen in sawi dun thei a, a chipchiar zawkin i hre thei bawk.
Take-Home Thuchah a ni
- Biologic Therapy hi asthma natna khirh tak tak, damdawi pangngai hmanga control harsa tak takte tan chuan enkawlna hmanraw changkang tak a ni.
- Hei hi Asthma damdawi a ni lova, mahse natna thunun nan a pui hle.
- He enkawlna hi i dawn lai hian i inhaler leh i doctor-in a pek damdawi dang zawng zawng hman chhunzawm zel a pawimawh hle.
- He enkawlna hi i tan a tha em tih chu i natna lan chhuah dan leh thisen test report bik ngaihtuah hnuah a ni ang.
- Enkawlna result a lan theih nan thla engemaw zat a la ngai thei a, chuvangin enkawl lai hian dawhthei taka awm a, damdawi lam thupek zawm a pawimawh hle.
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