Engtin nge hnute cancer i vei theihna chance? Hemi chungchang hi han sawi ila (Breast Cancer Risk Assessment)!

I dam em? Vawiin hian hmeichhe tam tak tan thupui pawimawh tak, leh hlauhawm deuh deuh kan sawi dawn a ni. Chu chu hnute cancer risk assessment a ni. Ngaihtuah buai suh, hei hian cancer i vei leh neih loh chu chiang takin a hrilh thei lo che. Mahse, i risk chu eng nge ni tih hriatthiamna a pe thei che a ni.

Breast Cancer Risk Assessment hi eng nge ni?

A awlsam zawngin, hei hi i dam chhunga hnute cancer vei theihna chance, a nih loh leh i probability thlir dan a ni. Entîr nân, ram ṭhenkhatah chuan hmeichhia pariat zînga pakhat vêl chuan an dam chhûngin hnute cancer an vei ang. Chuvangin, he assessment hian an zingah i tel ve em tih te, i risk chu mi pangngai aia sang emaw a hniam emaw tih rough idea i neih theih nan a pui thei che a ni.

A pawimawh ber chu, hei hian "cancer i vei ang" emaw, "i vei lo ang" emaw a ti lo. I kum leh i background nena khaikhin chuan risk i neih tam zia a lantir mai a ni. Tunah hian heng hmanrua te hi hmeichhiate tan duan a ni. Mipa hnute cancer vei theihna tehna atan an hmang lo.

Engtin nge heng risk assessment model te hian hna an thawh?

Tunah hian hetiang risk assessment method hi sawmhnih leh pali vel a awm tawh a ni. Chung zinga a tam zawk chu online questionnaire angin a awm a ni. Heng zawhnate hi minute sawm chhung lek chhungin i chhang thei a ni. I chhanna a\angin i risk factors a\angin score chu chhut a ni . Risk factor chu tun dinhmunah natna, a bik takin hnute cancer i vei theihna tipungtu thil a ni.

Chuti a nih chuan heng risk factor lian ber berte hi engte nge ni?

Eng thil nge hnute cancer hlauhawmna tipung thei tih i lo en ang u.

• Kum: Kum upat deuh deuh hian hnute cancer vei theihna a pung zauh zauh a.
• Chhungkaw zinga hnute cancer vei tawh: Chhungkaw member hnai tak (first-degree relative), i nu, i farnu emaw, i fanu emaw chuan hnute cancer a vei tawh a nih chuan, emaw, chhungkaw member engemaw zatin an vei tawh a nih chuan i hlauhawmna a sang zawk a ni.
• Genetic mutations: Mi thenkhat chuan an gene-ah hian inthlak danglamna engemaw zat an nei thei. A bik takin, gene `(BRCA1)` leh `(BRCA2)`-a mutations hian hnute cancer vei theihna nasa takin a tipung a ni.
• Race/ethnicity: Hnam thenkhat chu risk sang zawk an ni. Entirnan, Ashkenazi Juda hnam chhuakte hian `(BRCA1)` emaw `(BRCA2)` genes-ah mutation an nei tam zawk a, chu chu hnute cancer vei theihna a sang zawk tihna a ni.
• Breast density: Hmeichhe thenkhat chuan an hnuteah fibrous tissue leh glandular tissue an nei tam zawk a, fatty tissue an nei tlem zawk bawk. Chungte chu hnute dense an ti a.A nei te hi thau tam zawk nei te aiin an hlauhawm zawk.
• Hnute biopsy hmasa: I hnute biopsy i neih tawh a, result-ah cell than dan pangngai lo, atypical hyperplasia ang chi a awm chuan i risk a sang zawk.
• Hormone exposure: I taksaah hormone estrogen leh progesterone tamna rei tak i neih hian i risk a tipung a ni. Hei hi i taksain a pianphung a siam hormone (thlasik nena inzawm) vang a ni thei a, damdawi thenkhat i ei vang pawh a ni thei bawk. Entirnan, naupai venna damdawi thenkhat leh hormone replacement therapy (HRT) te pawhin i hlauhawmna a tipung thei bawk.
• Age at menarche: Kum naupang tak atanga puitlin i tan a nih chuan (menarche) , i taksa hian hormone a tawk rei tawh tihna a ni. Hei hian i risk a tipung bawk.
• Menopause-a kum: Tin, i period, emaw, menopause , chu a tlangpui aia tlai a nih chuan, hormone i hman rei zawk avangin i hlauhawmna a sang hle bawk.
• Childbirth history: Hmeichhia fa nei ngai lote chu fa nei tawhte aiin an hlauhawm zawk. Hei hi a chhan chu thlasik hun an nei tam zawk a, hun rei zawk hormone an tawrh vang a ni. Tin, fa i nei tawh a nih chuan, a bik takin kum 35 hmaa i fa hmasa ber i neih chuan, hnute cancer i vei theihna a hniam zawk. Fa i neih tam poh leh naupang pakhat tan risk a hniam zawk.

Mahse, heng risk factor zawng zawng hi a pawimawh vek lo tih hre reng ang che. Entirnan, kum upat dan azirin a hlauhawmna a sang deuh laiin, ``(BRCA1)`` gene mutation nei chuan hnute cancer vei theihna chance chu 60% in a sang thei a ni. Heng zinga pakhat pawh hian high-risk category-ah a dah thei che a ni.

Risk assessment method hrang hrang hian heng thilte hi a danglamin an ngaihtuah a, weighting hrang hrang an pe thin. A hmanraw hman tlanglawn tak tak thenkhat han thlir ila.

Risk assessment model hman tam berte chu engte nge ni?

Thil tih dan hrang hrang awm mah se, a bulpui tlemte kan sawi dawn a ni.

1. Gail model (Gail model - BCRAT) tih a ni.

Hei hi hmanraw lar ber a ni. National Cancer Institute (National Cancer Institute)-in test a neih zinga mi a ni. (BCRAT) an ti bawk. Kum 1989 khan hman tan a ni a, kum nga chhunga invasive breast cancer vei theihna tur leh kum 90 thlenga vei theihna tur a thlir a, minute nga vel chhunga tih theih a ni.

Heta zawhna zawh turte chu:

• i kum zat.
• I hnam/hnam.
• Fa neih dan chanchin.
• Tun hmaa hnute biopsy test te.
• Thlasik tan tirh atanga kum upa.
• Chhungkaw history-a hnute cancer vei tawh.

Kum nga chhunga i risk chu 1.67% aia tam a nih chuan "high risk" anga ngaih i ni. I doctor chuan cancer vei theihna tihtlem nan tamoxifen leh raloxifene ang chi damdawi a pe thei ang. Mahse he method hian mi zawng zawng tan a thawk vek lo. Hnute cancer i lo vei tawh a nih chuan, emaw, i risk tipungtu genetic mutation i nei tih i hriat chuan, he method hi chutiang chuan rintlak a ni lo.

2. IBIS model (IBIS - Tyrer-Cuzik model) hmanga siam a ni.

Hetiang method hian kum 10 chhunga cancer vei theihna tur emaw, dam chhunga cancer vei theihna tur a enfiah a ni.

Hemi chungchanga i hriatte chu:

• Kum, hnam/chi.
• Hnute density a awm.
• Fa neih dan chanchin.
• Taksa Mass Index (BMI) a ni.
• Tun hmaa hnute biopsy test te.
• Ovarian cancer chanchin.
• Chhungkaw history-a hnute cancer vei tawh.
• Thlasik tan leh tawp kum.
• Hormone thlak danglamna (HRT) hman dan.
• `(BRCA1)` emaw `(BRCA2)` emaw gene mutation a awm leh awm loh hriatna.

Gale model ang bawkin hei hi hnute cancer vei tawh tan chuan a thawk thei lo. Heng result atang hian i doctor chuan hnute screening vawi engzat nge neih tur tih emaw, BRCA genetic testing neih tur nge tih emaw a rel thei a ni.

3. BCSC Risk Calculator (Hnute Cancer enkawltu Consortium-in Risk Calculator a siam) .

Hei hian kum nga chhunga invasive breast cancer emaw, kum ruk chhunga metastatic breast cancer emaw vei theihna a en a ni. `Metastatic` cancer chu hnute atanga intan a, taksa peng dangah a darh thin a ni.

Heta zawhna zawhte hi a hmaa zawhnate nen a inang hle. Kum, hnam, hnute density, naupang awm zat, BMI, biopsy result hmasa, cancer history (mimal leh chhungkaw), menopause lai kum, HRT hman, etc. Heng result te hian mammogram engzat nge i neih tur tih i rel thei a ni.

4. BRCAPRO a ni

Hetiang method hian `(BRCA1)` emaw `(BRCA2)` gene mutation i neih theihna tur a en ber a ni.

Hei hian i chhungkaw history-a hnute emaw ovarian cancer emaw chungchang zawhna a zawt ang. Chumi awmzia chu:

• Cancer hmuhchhuah a nih lai khan an kum.
• Tuna an kum (or thih huna an kum) hi.
• Hnam/hnam (a bik takin Ashkenazi Juda hnam).
• Cancer kaihhnawih genetic test result (`(BRCA1, BRCA2)` ang chi).
• Cancer kaihhnawih surgery (`(mastectomy)` - hnute lakchhuah, `(oophorectomy)` - ovary lakchhuah) i nei tawh em tih pawh.

Heng result te hian genetic test neih hi a tha em tih a hriattir thei che a ni.

5. BOADICEA (CanRisk hmanrua) 1.1.

Hei hi BRCAPRO ang bawkin chhungkaw chanchin leh genetic information atanga siam a ni. Breast cancer bakah ovarian cancer vei theihna a en bawk. Online tool pakhat CanRisk tih a awm a. Kum, BMI, hnute density, fa neih dan, birth control pill hman dan, menarche-a kum, chhungkaw cancer history leh genetic mutations hriatna te pawh a zawt bawk. Hei hian genetic testing neih a ngai em tih leh testing schedule chu eng nge ni tur tih hriat theihna a pui bawk.

6. BWHS Breast Cancer Risk Calculator (Hmeichhe dum hriselna zirchianna hnute cancer hlauhawmna chhut) .

Hei hi hmeichhe dum tan bik siam a ni a, a chhan chu hnute cancer hlauhawmna tehna atana hnam leh chi hi thil pawimawh tak a nih vang a ni. I risk i chhut dawn hian i hnam/chi hian i risk score a nghawng dan ngaihtuah a pawimawh. Sawi tawh ang khan hei hian kum, BMI, nau neih dan, biopsy history, birth control pills, menarche-a kum, chhungkaw history, leh i ovary i lakchhuah tawh leh tawh loh te pawh a zawt bawk.

Engtin nge doctor hian heng result te hi a hman?

Hetiang online assessment i neih a, "high risk" i nih i hmuh chuan hlauhna leh lungkhamna i neih hi thil pangngai a ni. Mahse, chu result atang chuan thutlukna siam suh. Hei hi doctor nen in sawiho tur a ni. Heng result te hian i doctor chu i hnute hriselna enfiah dan tur ruahmanna siam turin a pui ang a, symptoms te chu a hmain a hriatchhuah theih nan leh enkawl tan dan tur a ruahman sak ang.

Results a zirin i doctor chuan a hnuaia mi ang hian a ti thei ang:

• Breast cancer screening (e.g., mammograms) neih hma leh a hma aia tam zawk neih tir i ni thei bawk.
• Genetic counseling hian cancer vei theihna tipungtu genetic mutation i neih leh neih loh a hriat theih nan a pui thei che a ni. I nei tih i hriat tawh chuan i hriselna leh i chhungte a nghawng theih dan tur (entir nan, naupangin gene a rochun theihna chance) hriatthiamna a pe thei che a ni.
• Damdawi tamoxifen leh raloxifene te hi hnute cancer hlauhawmna tihziaawmna atan pek theih a ni .
• A hlauhawmna a sang hle a nih chuan prophylactic mastectomy (cancer a lo awm hmaa hnute lakchhuah) tih a tha thei. Hei hian cancer vei theihna nasa takin a tihziaawm thei a ni.

Heng risk assessment te hi engtiang chiahin nge rintlak an nih?

Heng assessment methods te rintlakzia hi siamna atana data set hman danah a innghat a ni. Heng hmanrua te hian cancer vei tawhte hnen atangin information an la khawm a, an risk factors te chu assessment titu risk factors te nen an khaikhin thin. Mahse, population data hi 100% a dik thei lo a, tu pawh mimal hriselna a hrilhfiah thei lo. Risk factor engzat pawh inang mahse mi pahnih hi an inang chiah ngai lo.

A tih theih lohna thenkhat chu hetiang hi a ni:

• Hnam/chi hrang hranga data hrang hrang:Estimate siamna atana hman demographic data a zirin result chu i tan a inmil lo mai thei. Entirnan, breast cancer data hi tunhma atang tawhin Hispanic ni lo mipa hring atanga lakkhawm tam zawk a ni. Tunah chuan hnam dangte tan data lakkhawm ni mah se, estimate zawng zawng hian heng danglamnate hi inang tlangin a enkawl vek lo.
• Cancer chi hrang hranga hman theih: Test tam zawkah chuan cancer la vei lote zingah cancer nasa tak leh darh zau tak awm theihna a en a. Cancer vei tawhte chanchin an sawi lo.
• Risk factors tling lo: Screening method pakhat mah hian hnute cancer chi hrang hrang risk factor zawng zawng a ngaihtuah vek lo. Tuna screening method tam zawk hi chu genetic risk factors emaw, i health history nena inzawm risk factors emaw a ni. Chuvangin i doctor chuan thlalak kimchang zawk hmuh theih nan screening method engemaw zat neih a rawt mai thei.

Mahse, heng hnute cancer risk assessment methods te hi doctor ten an la hmang reng a, a chhan chu mi pakhat risk rough estimate pe thei tur khawpa tha an nih vang a ni. Researcher-te chuan an hlawhtlinna tihchangtlun dan tur an zawng mek a ni.

A tawp berah chuan thil hriat reng tur

Okay, chuvangin kan sawi tawh atang hian ngaihdan i neih ka beisei.

Breast cancer risk assessment hian cancer i vei dawn em tih chiang takin a hrilh thei lo. Mahse, i doctor chu eng thil nge i hlauhawmna tipung thei tih a hriatthiam theih nan a pui thei a ni.

Hnute cancer screening hi mi zawng zawng tan a pawimawh hle. Risk assessment hi doctor-in i hnute hriselna a enfiah theihna atana hmanraw dang pakhat chauh a ni. He assessment hian BRCA gene awm leh awm loh genetic test-ah a hruai thei che a ni. Test neih fo a ngai mai thei. A tawpah chuan heng zawng zawng hian i doctor chu a tir lamah cancer a vei theih nan a pui a, chutih hunah chuan tihdam theih a ni. Chuvangin Doctor nen pawh sawipui hlau suh la, a tul angin hma la rawh.

` Hnute cancer, cancer hlauhawmna, hmeichhe hriselna, genetic test, mammogram, hormone, Breast Cancer Risk Assessment