Cancer hi i ruh thlengin a darh thei em? (Bone Metastasis) Hemi chungchang hi han sawi ila!

Cancer vei, a hnuah ruh na emaw, ruh chak lo emaw a nei tih i hre tawh mai thei. Hei hi nangmah ngeiin i tawng tawh mai thei. Hei hi a takah chuan cancer cells taksa peng khat atanga ruh thlenga darh vang a ni. Hei hi ruh metastasis kan ti a ni . Hei hi natna khirh tak ni mahse, hlauthawng suh. A pawimawh ber chu fimkhur a, uluk taka enkawl hi a ni.

Bone Metastasis tih hi eng nge ni? A awlsam zawngin i hrethiam ang u.

A awlsam zawngin, bone metastasis chu i taksa hmun danga cancer cell (hnute, lung, emaw prostate ang chi) atanga lo chhuak cancer cell te chu i thisen kal tlangin i ruh thlengin an kal a, chutah chuan an lo thang lian tan a ni. Hei hi metastatic cancer chhinchhiahna pakhat a ni .

Hriat tur pawimawh tak chu hei hi primary bone cancer a ni lo tih hi a ni. Hei hi hmun dang atanga ruh thlenga darh cancer a ni.

Vanduaithlak takin he natna hi damdawi a la awm lo. Mahse, natna lan chhuah dan control leh natna zual zel tur tikhawtlai thei tur enkawlna tam tak a awm. Thil dang pakhat chu cancer natna vei hian a hma aia rei an dam rei tawh avangin ruh metastasis a tam chho zel a ni. Zirchianna pakhatah chuan ruh metastasis vei zat chu cancer hmuhchhuah a nih hnu kum khatnaah 3% aṭangin kum 10 hnuah 8%-ah a pung tih a tarlang.

Hei hi eng symptoms nge ni? Hengte pawh hi i nei em tih en rawh

A lan chhuah dan tlangpui chu ruh natna a ni . Thil pakhat chu a hrual emaw, a rit emaw ang maiin a lang thei. Zanah a na zual thei a, a bik takin zan lamah a na zual thei. A châng chuan a nalh thei a, a hrual thei a, a hrual thei bawk.

Bone metastasis hian harsatna dang a thlen thei bawk. A kaihhnawih symptom bik a awm bawk:

• Bone Fractures: Hetiang dinhmun hian i ruh a ti chhe hle. Phên dangin sawi ila, ruh pakhat chu tlu lian tham awm lovin i tikehsawm thei a ni. I taksa ruh eng pawh a nghawng thei. Mahse a tam ber chu ruhro, ruhro, pelvis, humerus, femur leh luruh te a ni. Ruh a tliak hian a na hi a na hle a, a na hle bawk. Kut emaw ke emaw i tihchhiat chuan i che thei lovang.
• Hypercalcemia: Hei hi i thisena calcium level a san lutuk hian a ni. A lan chhuah dan chu luak chhuak, chaw ei kham, chaw ei chak lohna, luak chhuak, leh luak chhuak te a ni.
• Spinal Cord Compression: Tumor a darh a, i spinal cord a nawr mek a nih chuan i hnungzang na, i kut leh keah chak lohna emaw, rilru hahna emaw, zun insum theih lohna i nei thei. Hei hiEmergency anga enkawl tur a ni.

Engvangin nge hetiang hi a lo awm? Eng nge a chhan?

Hetiang dinhmun hi cancer tumor atanga cell te an inthen a, i thisenah an lut a, chu chu an kal tlang a, chu chu i ruh thlengin an kal a ni. Chutah chuan an thlen chuan, chu cancer cell-te chuan mithiamte chuan "vicious cycle of bone metastasis" an tih chu an tan ta a ni.

He cycle hi hriatthiam theih nan i ruh cell te hnathawh dan tlem tal hriat a \angkai hle. Kan ruh chhungah hian cell chi hnih a awm a, chungte chu osteoblasts leh osteoclasts te an ni.

• Osteoblasts hi ruh thar siamtu cell a ni.
• Osteoclasts chu ruh cell hlui, chhe tawhte chu a hmin, a chhe a, a paih chhuak thin cell a ni.

A tlangpuiin heng cell chi hnih hian ruh cell thar siam chhuah leh ruh cell hlui thlak danglamna inkara inthlauhna vawng reng turin an thawk ho thin. Mahse cancer chu ruh chhunga a luh chuan he kalphung hi a kal sual ta a ni. Hetah hian thil thleng chu a awm:

• Osteoblasts hian ruh cell thar tam lutuk a siam chuan i ruh chu a pung nasa lutuk ang a, ruh siam dan pangngai lo hmun i nei ang. I doctor chuan heng hmunte hi osteosclerotic lesions emaw osteoblastic lesions emaw a ti thei ang . Heng hmunte hi pawn lam atang chuan a khauh hmel hle mai thei a, mahse an chhe hle a, lui kama vur hring hring ang mai a ni. An chhe thei a, an chhe thei bawk.
• Osteoclasts te hian ruh cell te chu a tlangpui aia rang zawka an tihchhiat chuan i ruh cell atanga thil chhuak te hian i ruh ah hian khur te te a siam thei a ni. Microscope hmanga i en chuan mi pakhatin i ruh chhunga khur a siam ang mai a ni thei. I doctor chuan heng holes te hi osteolytic lesions a ti a . Heng hliamte hian i ruhte chu a ti chhe zawk a, a tichak lo zawk bawk. Hei hian ruh tliak theihna a tipung a ni.

Research atanga a lan dan chuan ruh cell chi hrang hrang leh metastatic cancer chi hrang hrang inzawmna a awm a ni. Entirnan, prostate cancer atanga ruh metastase 70% atanga 85% vel chu osteogenic a ni a, chu chu osteoblasts ruh tam lutuk avanga lo awm tihna a ni. Mahse, hnute cancer atanga metastase 75% chu osteolytic a ni a, chu chu ruh cell a chhe rang lutuk vang a ni tihna a ni.

Engtin nge hei hi i hriat chian?

I doctor chuan he natna hi a hriat theih nan imaging test hrang hrang engemaw zat a ti ang. Thisen test emaw, zun test emaw pawh an ti thei a, ruh chhiatna tilang thei thil an zawng thei bawk. Imaging test-ah hian:

• Ruh scan a ni
• CT scan (Computed tomography - CT scan) hmanga tihchhuah a ni.
• MRI scan (Magnetic resonance imaging - MRI scan) hmanga enfiah a ni.
• PET scan (Positron emission tomography - PET scan) hmanga enfiah a ni.
• X-ray hmanga tih a ni

Heng test te hian i ruh chungchanga thil thleng dik tak te, cancer cells te a darh tawh em tih te, eng chen nge an darh tawh tih te a hriattir thei che a ni.

Enkawlnate chu engte nge ni?

Vanduaithlak takin ruh metastasis hi damdawi a awm lo. Mahse, natna tihziaawmna tur leh natna kal zel dan tur thunun thei damdawi leh enkawlna a awm . Heng enkawlnate hian i nunphung tihchangtlunna kawngah kawng thui tak a zawh thei a ni.

Enkawl dan tlangpui thenkhat chu hetiang hi a ni:

• Bisphosphonates: Heng damdawi (e.g., Pamidronate, Zoledronic acid (Zometa®)) hian i ruh a tichak a, i thisena calcium awm zat a ti tlem a, hypercalcemia vei theihna a ti tlem bawk.
• Chemotherapy emaw hormone therapy: I ruh thlenga cancer cell darh (metastases) hmun khat aia tam i neih chuan i doctor chuan he damdawi hi a pe thei ang.
• Monoclonal antibody therapy: Ruh tliak hlauhawmna tihziaawmna turin damdawi Denosumab (Prolia® emaw Xgeva®) pek thin a ni.
• Radiation therapy: I ruh pakhata tumor avanga natna i neih chuan chu natna chu enkawl nan radiation therapy pek theih a ni. Spinal cord compression avanga natna awmte tan pawh a pui thei bawk. I doctor chuan radiation therapy bakah hian corticosteroids a pe thei bawk.
• Kyphoplasty: Hei hi spinal compression fracture enkawlna a ni.
• Surgery: I doctor chuan ruh chhe thei tak takte tihchak nan emaw, cancer natna hrik paih chhuah nan emaw operation neih a rawt thei ang.

I doctor chuan i tan a enkawl dan tur tha ber a rel dawn tih hre reng la, chuvangin hemi chungchang hi uluk takin sawipui rawh.

Enkawl loh chuan eng nge thleng ang?

Bone metastasis hi enkawl loh a nih chuan hypercalcemia ang chi harsatna a awm thei a ni. Enkawl loh chuan hei hian coma a thlen thei a ni. Tin, ruh tliak vangin i kal thei lo emaw, i hna i thawk thei lo emaw pawh a ni thei bawk. Ruh natna nasa tak hian nun nuam i tih theihna a ti tlem thei a ni. A pawimawh ber chu, spinal cord compression hian enkawl loh chuan paralysis a thlen thei a ni. Chuvangin, a symptoms te chu ngaihthah suh.

Bone metastasis i neih chuan eng nge beisei tur?

Bone metastasis i neih chuan i taksa peng dang atanga cancer chu i ruh ah a darh tihna a ni. Hei hi cancer natna zual zel chhinchhiahna a ni . Chutiang a nih chuan primary cancer leh bone metastasis pahnih tan damdawi leh puihna i mamawh ang.

Hlauthawng lo, damdawi lam thurawn zawm a, positive taka awm a pawimawh hle.

Hetiang dinhmun hi eng chen nge i dam theih ang?

He zawhna hi chhanna pakhat chauh pek a har khawp mai. A chhan chu thil tam takah a innghat a ni. He hun hi a inang lo thei a, a tlangpuiin thla ruk atanga kum li aia tam a ni. A nghawngtu ber chu:

• Cancer chi: Zirchianna pakhatah chuan lung cancer ruh thlenga darh tawh tan chuan thla ruk atanga thla sarih vel a ni a, prostate cancer ruh a darh tawh tan chuan thla 53 vel a dam rei thei thung.
• Cancer Stage: Stage I (Stage I)-a cancer vei te chu stage IV (Stage IV)-a hmuhchhuah te aiin ruh metastases an vei tlem zawk. Entirnan, cancer hmuhchhuah a nih atanga kum 10 hnua ruh metastases rate enfiahtu zirchiangtute chuan stage I vei zinga 3% chuan he natna hi an vei tih an hmuchhuak a, stage IV vei zinga 28% chuan an vei thung.

Stage 1 cancer ka nei a, chu chu remission-ah a awm. Engvangin nge ka cancer hi a darh?

Vanduaithlak takin, a châng chuan cancer enkawl a nih hnu leh remission -a a awm hnuah pawh metastatic cancer, bone metastasis tia hriat bawk chu a lo awm thei a ni. ``Remission'' tih hian symptom i nei lo tihna a ni a, test-ah pawh cancer chhinchhiahna hmuh tur a awm lo tihna a ni. Bone metastases i neih chuan i doctor chuan he natna hi distant recurrent cancer tiin a sawi thei bawk. Recurrent cancer chu enkawl hnua cancer a lo let leh hi a ni.

Engtin nge ka in enkawl ang?

Bone metastasis hian i nunphung a nghawng thei a ni. Natna ang chi symptoms leh cancer a darh zel nia hriatna nena nun hi thil awlsam a ni lo. Mahse, i ṭanpui thei tûr rawtna ṭhenkhat chu hetiang hi a ni:

• Ei tha rawh: Ruh metastases avanga harsatna awm hian i ei duhna a tichhe thei a ni. I tana tha tur ei leh in hrisel tak siam turin nutritionist nen inbia ang che.
• Cancer damchhuak program te hi han ngaihtuah teh: I cancer hmuhchhuah ni atang khan cancer damchhuak i ni tawh a. Tunah chuan bone metastases i hmachhawn tawh a, chutiang bawk chu i ni tawh. Nangmah ang bawka dinhmun inang mite tanpui thei tur programme leh support group a awm thei bawk.
• Palliative care chungchang zawt rawh:Vawi tam tak chu ruh metastases chhinchhiahna hmasa ber chu ruh natna a ni. He natna hi a na thei hle a, i nunphung a nghawng thei bawk. Palliative care-ah hian natna damdawi leh natna enkawlna atana puihna dangte a tel a ni. Palliative care-ah hian cancer thihpui tur i neih avanga rilru lama harsatna awmte i enkawl theih nan psychological counseling a tel bawk.
• Clinical trial en rawh: Zirchiangtute chuan cancer chi hrang hrang atanga ruh metastase awmte enkawl dan thar an zawng mek a ni. I doctor hnenah i tana tha thei tur clinical trial chungchang zawt rawh.

Hospice care hi ka ngaihtuah tur em ni?

I dinhmun a zirin a ni. I doctor chuan i cancer chu enkawl chhunzawm zel chuan a dam mai thei lo tih a ngaihtuah a, enkawlna tihtawp a nih chuan thla ruk emaw a aia rei lo dam hun i nei tih a ngaihtuah chuan, hospice care -ah enkawl a rawt thei ang Hospice care hian i taksa hahdamna, natna laka zalenna leh natna lan chhuahna dangte enkawl dan a ngaihtuah ber a ni.

Engtikah nge ka doctor ka hmuh ang?

I ruh metastases symptoms a na zual zel a nih chuan, entirnan, damdawi pek tawh pawha i thunun theih loh natna i neih chuan doctor pan nghal rawh. Ruh metastases natna nasa tak nen hian i nunpui a ngai lo tih hre reng ang che. I doctor chuan natna tidamtu damdawi leh i nunphung tichhe lo tur enkawlna dang a pe ang a, chutah chuan i hmangaih tak takte bula awm theihna tur pawh a tel ang.

Engtikah nge Emergency Room-ah ka kal ang?

Spinal cord compression symptoms i neih chuan 911 call emaw, emergency room-ah emaw kal nghal tur a ni. Heng symptoms te hi:

• I ke, i ke kephah emaw, i pum hnuai lam emaw chu a hring emaw, a hring emaw a nih chuan.
• I ke i tihchet harsat chuan.
• I zun leh ek i thunun theih loh chuan.
• I zun theih loh chuan.

Enkawl loh chuan spinal cord compression hian paralysis a thlen thei a, chuvangin heng symptoms te hi fimkhur hle ang che.

Doctor hnenah eng zawhna nge ka zawh ang?

Bone metastasis i nei tih hriatchhuah hian, cancer i hmachhawn tawh laiin, i nunphung a tichhe zual thei a ni. I doctor zawh theih tur zawhna thenkhat chu hetiang hi a ni:

• Tunah hian ka ruh zingah eng nge cancer cell-in a khat?
• Engtin nge ruh cancer neih hian ka prognosis pum pui a nghawng?
• Eng enkawlna emaw, enkawlna inzawmkhawm emaw hian min pui thei ang?
• Treatment-te hian ruh metastases chu ruh dang a darh loh nan a titawp thei ang em?
• Ka ruh natna enkawl dan tur chu engte nge ni?
• Engtin nge ruh tliak hlauhawmna hi ka tihziaawm theih ang?

Bone Cancer leh Bone Metastasis hi eng nge an danglamna?

Hei hi mi tam tak tibuaitu a ni.

• Bone cancer hi i ruh atanga intan cancer chi khat a ni a, chu chu osteosarcoma emaw Ewing sarcoma emaw a ni.
• Bone metastasis chu i taksa hmun danga cancer intan chu a hnua i ruh thlenga a darh chuan a ni.

Bone metastasis hi metastatic cancer chhinchhiahna a ni. Bone metastasis i nei tih an hrilh che a, chu chu i cancer hi a bul tanna atanga a darh tih i hriat hmasak ber a ni. Thuthang chuan a tithinur thei a, a ti lungngai thei bawk. Chu bâkah, ruh metastasis hian natna a thlen reng a, i nunphung a nghawng tih hriat chu a lungchhiatthlâk lehzual thei bawk. Eng nge i beisei leh ang tih chu i lungkham a, i hlau mai thei. Mahse, i doctor-te chu i thusawi ngaithla tur leh i ngaihtuahnate hrethiam turin an awm tih hre reng ang che. I natna enkawl dan atanga i cancer a darh chuan eng nge i beisei tur tih sawifiah thlengin engkim ah an pui thei che a ni.

A tawp berah chuan take-home message:

Bone metastasis hi natna khirh tak ni mahse, enkawl dan tur a awm.

• A pawimawh ber chu hlauthawng lo leh doctor thupek uluk taka zawm hi a ni.
• Natna thunun tur leh nunphung tha tak vawng reng turin enkawlna a awm.
• Nangmah chauh i ni lo. Chhungte, ṭhiante, doctor leh healthcare professional-te ṭanpui turin i nei a.
• He zinkawngah hian positive leh rilru lama chak taka awm hi a pawimawh hle.

Hemi chungchanga zawhna dang i neih chuan i doctor zawh hreh suh. Engkim a hrilhfiah vek ang che.

` Cancer, ruh metastasis, ruh na, cancer darh zau, cancer enkawl, calcium tihpun, ruh (spinal compression) te