Cancer Cachexia: Hemi chungchang hi kan sawi dawn em ni?

Nangmah emaw, i hriat mi emaw cancer vei i nih chuan hun kal zelah an taksa chu a lo hring tawh a, a hmel pawh a danglam tawh tih i hre tawh mai thei. Mi tam tak chuan hei hi cancer atanga lo chhuak emaw, enkawlna avanga side effect emaw chauh niin an ngai. Chu chu eng emaw chen chu a dik mai thei. Mahse, he dinhmun hi a châng chuan thil thuk zâwk a ni thei a, chu chu cancer cachexia . Hemi chungchang hi vawiinah hian chipchiar zawkin han sawi ila, a chhan chu cancer vei te nunphung leh enkawlna an dawn dan a nghawng avangin.

Cancer Cachexia hi eng nge ni?

A awlsam zawngin sawi ila, cancer cachexia hi cancer vanga chhiatna nasa tak (severe wasting syndrome) a ni. Hei hi ruhro leh taksa thau tam tak i hloh hun a ni . Thau tihtlem mai ni lovin, chakna petu taksa peng (muscle) pawh a ni. Hetianga i taksa rihna tihtlem hian i hmel a tidanglam thei a, rilru lama harsatna a thlen thei a, cancer enkawlna pawh a ti harsa thei bawk. I nunphung a nghawng thei bawk a, a chang chuan cancer i tuar theihna a tibuai thei bawk.

Mithiamte chuan he natna hian cancer vei zinga 50% vel a nghawng niin an sawi. Tin, cancer darh tawh zinga 75% velah hmuh theih a ni bawk a, chu chu Stage IV cancer-ah a ni. Lungchhiatthlak takin he natna hian cancer avanga thihna 25% a thlen a ni.

Hetiang dinhmun hi cancer chi hrang hrangah pawh awm thei mahse, a bik takin heng cancer chi hrang hrang vei teah hian a awm fo thin:

• Colorectal cancer a ni
• Lung cancer a ni
• Melanoma, vun cancer chi khat
• Pancreatic cancer natna a ni

Doctor-te chuan cancer cachexia chu an tidam kim thei lo nain, enkawlnaah chuan i ei tam lutuk chu tihpun an tum a, a bîk takin protein tamna, calorie tamna ei tûrte chu an ngaihtuah ber a ni

Cancer cachexia natna lan chhuahna chu engte nge ni?

Hetiang natna lan chhuahna ber leh langsar ber chu thla 6 atanga thla 12 kalta chhunga i taksa rih zawng zawng zawng atanga 10% aia tam i tlahniam hi a ni Hei hian taksa ruh leh thau te a huam vek a ni. Chu bakah chuan symptom dang engemaw zat a awm thei bawk:

• Chauhna leh chak lohna nasa tak: Nitin hna thawk tur te, chhungkua enkawl tur te, mimal hna pawh thawk tur pawhin chakna i nei tlem hle niin i inhria mai thei. Nunna nei lo ang mai a ni.
• Muscle wasting: Doctor-te chuan hei hi muscle wasting emaw muscle atrophy emaw an ti bawk. Hei hi taksa ruh (muscle mass) hloh leh taksa ruh (muscle wasting) a ni.
• Anorexia: Hei hi ei duhna zawng zawng i hloh a, i ril a tam lo. A chang chuan ei tur ngaihtuah pawh i duh lo. Mahse hei hi ei leh in lama harsatna kan hriat tawh anorexia nervosa nen chuan a danglam hle.
• Anemia: I taksain inflammation a chhannaah thisen sen siam chhuahna tichhe thei protein a chhuah avangin thisen tlakchhamna i nei thei a ni.
• Hri kai fo: Cancer cachexia hian i taksa hriselna a tichak lo thei a, natna do thei lo a ni. Hei hian natna hrik i kai theihna a tipung thei a ni.

Engvangin nge he cancer cachexia hi a lo awm?

Hei hi chhan hrang hrang a awm a. Cancer hian i metabolism a ti chak a . Chumi awmzia chu i taksa hian ei leh in atanga chakna tam zawk a mamawh tihna a ni. Chutih rual chuan cancer leh cancer enkawlna hian i ei duhna a ti tlem thei bawk. Chumi rah chhuah chu i taksain nutrient tam zawk a mamawh laiin i ei tlem a ni.

He dinhmun hi a bik taka nghawng thei chhan thenkhat chu hetiang hi a ni:

• Cytokines chi hrang hrang: Cytokines hi kan immune system hian virus ang chi invader te a chhan dan leh a chhan dan tur control tu chemical a ni. Cancer cachexia-ah chuan i immune system hian cytokines chi hrang hrang a tichhuak thin. Chungte chuan inflammation a thlen a, chu chuan i taksain thau leh thau a tihchhiat chakna a tipung a ni. Cancer hian inflammation a thlen bawk a, heng cytokines te hian chu inflammation chu a tizual thei a ni.
• Cancer symptoms leh side effects: Cancer avanga natna, luak chhuak leh luak chhuak hian ei a ti tlem thei hle. Tin, cancer i neih hian lungngaihna a thlen thei a, ei duhna a hloh thei bawk.
• Cancer enkawlna avanga nghawng tha lo: Surgery, radiation therapy , chemotherapy , leh opioid painkiller thenkhat ang chi thilte hian ei harsa a ti thei a, taksain ei tur tha a lakluh theihna a tibuai thei bawk.
• Insulin resistance: Hei hian i taksa ruh leh thau cell te hian insulin an dawng tha lo tihna a ni. He insulin resistance, cachexia-a awm hian taksa ruh (muscle wasting) a tipung thei a ni.
• Protein turnover tihpun: Protein turnover chu i cell chhunga protein hlui awmte chu protein thar hmanga thlak a ni. Hei hi protein tihchhiat hmanga thleng a ni . Cancer cachexia-ah chuan cell-a protein awmte chu a chhe rang lutuk a, protein tharin a thlak thei lo. Hei hian taksa ruh (muscle wasting) a thlen bawk.

Cancer cachexia hian eng harsatna nge a thlen?

Hetiang dinhmun hi nunna atana hlauhawm pawh a ni thei. Entirnan, cachexia hi han ngaihtuah teh, chu chu metastatic solid tumor, lung emaw prostate cancer ang chi, cancer chu taksa hmun dangah a darh chuan 20% atanga 25% vel thihna thlentu ber a ni.

Harsatna dangte chu:

• Cancer enkawlnaah nghawng a neih: I taksa hian cancer enkawlna atanga a dam leh theih nan taksa ruh leh thau a mamawh a ni. Hengte hi hloh chuan cancer enkawlna i dawn theihna a nghawng thei a ni. Enkawlna tuar chhuak thei khawpa chakna pawh i hloh mai thei.
• Mental health issues: Cancer cachexia i vei tih hmuhchhuah a nih chuan thla tam tak chauh dam tur i nei tihna a ni thei. He hriatna hian lungkhamna leh lungngaihna nasa tak a siam thei che a ni.
• Chhungte leh ṭhiante chunga nghawng: Hetiang dinhmun hian chhungte leh ṭhiante nena in inlaichinnaah pawh harsatna a siam thei bawk. I taksaa inthlak danglamna i hmuh hian i lungngai thei mai ni lovin, i enkawltute pawhin i hriselna an ngaihtuah nasa zawk mai thei bawk. Zirna hrang hrangah chuan chhungte’n heng chhinchhiahnate hi an hmuh hian damlo chu hmangaihna avang pawhin ei turin an nawr luih thei tih a tarlang a, chu chuan a tul lova buaina a thlen thei a, dinhmun lungkham tawh tak chu a tizual thei a ni.

Ngaihtuah teh, chhungkaw member pakhat chu cancer vangin a thau a, chaw a ei thei lo a nih chuan, "Khawngaihin tlem tal ei la, khawngaihin hei pawh hi ei ve rawh," tih hi thil awmdan pangngai a ni. Mahse, chu chu damlo tân chuan a buaithlâk lehzual thei a ni.

Engtin nge doctor-te hian cancer cachexia hi an hriat theih?

I oncologist leh/ emaw palliative care team te chuan taksa lamah an enfiah ang che. I ei leh in chungchanga zawhna bu ziak turin an ti thei che a, i fitness zawng zawng leh i taksa chakna zawng zawng tehna tur test pawh an ti thei bawk.

Tin, CT scan emaw DXA scan emaw pawh a tha thei bawk. He DXA scan hian i kut leh kea lean tissue awm zat a teh thin. Oncologist hnenah i taksa ruh (muscle mass) chungchang ngaihtuahna a pe thei a ni. Heng test result hian doctor-in natna stage a hriat theih nan a pui dawn a ni.

Cancer cachexia hi eng stage nge awm?

Cancer cachexia hi stage lian pathum a awm a, chungte chu:

• Pre-cachexia: Hetiang stage-ah hian ei tha ei mahse i taksa rihna a tlahniam a ni. Mahse, thla 6-12 kalta chhung khan i taksa rih zawng zawng zawng 5% aia tam i hloh lo. I thau lutuk a nih chuan he i taksa rihna tlahniam hi a lang lo mai thei a, mahse test-naah chuan metabolic changes a awm a, thau rualin i taksa ruh a tlahniam tih a lang.
• Cachexia a awm chuan:Tunah chuan thla 6-12 kalta chhung khan i taksa rih zawng 5% aia tam i hloh tawh a, a nih loh leh i taksa rih zawng 2% aia tam i hloh tawh a, i body mass index (BMI) pawh 20kg/m2 aia tlem a ni tawh bawk. Test-ah hian taksa ruh (muscle wasting) leh inflammation chhinchhiahna a awm thei.
• Refractory cachexia: Hetiang dinhmunah hian i taksa rihna pangngai 20% aia tam i hloh tawh a, i BMI chu 27 kg/m2 aia tlem a ni (hei hi a sang hlein a lang thei a, mahse i rihna tlahniam nasa tak nen a inzawm chuan a na hle). I taksa rihna tlahniam hian i hmel a ti tha lo hle thei a, cancer enkawlna pawh i tuar thei lo hle bawk. Thil engemaw takah chuan cancer enkawlna hian hna a thawk tawh lo thei bawk.

Cancer cachexia enkawl dan tur chu engte nge ni?

I enkawlnaah hian ei leh in tihchangtlun dan tur a ngaihtuah ber ang . Entirnan, i cancer team leh palliative care team te chuan hetiang hi an rawt thei ang:

• Ei \ha rawh: Chaw tê tê leh chawhmeh chi hrang hrang , calorie, thau, leh protein tamna ei hi ngaihtuah rawh . Chaw te zawk ei hian calorie tam zawk i neih theih nan a pui ang. I ei apiangin eng ei tur nge i hlawkpui ber ang tih chu i nutritionist nen sawiho rawh. I ei leh inah cheese, butter, nut, leh skim milk ang chi thil dah tel an rawt mai thei.
• Supplements ei ve rawh: I oncologist emaw nutritionist emaw hnenah ei tur inkara i in theih emaw, i ei theih tur nutritional supplement chungchang zawt rawh. Chungte chuan extra nutrition a pe thei a ni.
• Exercise engemaw zat nei rawh: Exercise light hian taksa ruh hloh a ti hniam thei a, mahse hei hi doctor thurawn hnuaiah chauh tih tur a ni.
• I medical team-ah innghat rawh: I palliative care team hian rilru hriselna leh thlarau lam tanpuina ang chi thilah an pui thei che a ni. Chu thlawpna chu tun dinhmunah chuan a hlu hle.

Cachexia enkawlna tur damdawi a awm em?

Hetih lai hian ni lo. Research-in megestrol acetate an tih damdawi hian ei duhna a tipung thei a, taksa rihna a tipung thei tih a tarlang a, mahse U.S. Food and Drug Administration (FDA) chuan cancer cachexia enkawlna atan a pawm lo. A châng chuan, i doctor chuan hun rei lo tê chhûnga ei tûr corticosteroid a pe thei a ni .

Cancer cachexia vei chuan eng nge a beisei theih ang?

I dinhmunah a innghat tak zet a ni. Chu chu, eng stage-a cachexia i awm, eng stage-a cancer i neih tih hi a ni a, entirnan, pre-cachexia i neih chuan i ei leh in tur tihdanglam hian thau leh thau i hloh zat a ti hniam thei a ni. Mahse, vanduaithlak takin i ei tam zawk pawhin i hloh chu i titawp vek thei lo va, taksa ruh leh thau hloh chu i la let leh thei lo.

Cancer leh cachexia hmasawn tak i neih chuan, emaw, enkawlna dawng lo cachexia (refractory cachexia) i neih chuan i oncologist chuan i dam chhung tawp lam i hnaih tawh tih a sawi mai thei. Cachexia vei enkawl i nih chuan i medical team chuan i beisei tur chungchangah information tha ber ber an pe thei che a ni.

Cancer cachexia vei dam rei zawng chu engzat nge ni?

Mi tin dam rei zawng hi a inang lo. Cancer cachexia hian cancer natna zual tawhte a nghawng tlangpui nachungin, i cancer stage eng pawhah pre-cachexia symptoms i nei thei a ni. Chutiang a nih chuan kum tam tak chhung chu cancer leh cachexia ang chi harsatna nen i nung thei ang. Mahse, zirchianna chuan refractory cancer cachexia, cancer chi khat, enkawlna dawng lo, i neih hian cancer damchhuah theihna chance chu 30% velin a tihtlem thu a tarlang.

Cancer cachexia hi natna hian i metabolism-in ei tur atanga chakna a hman dan pangngai aia rang zawka a siam vang a ni. Tin, cancer leh cancer enkawl dan hian ei leh in mumal tak a veng thei bawk. Chumi avang chuan i rihna leh i taksa ruh (muscle mass) chu nasa takin a tlahniam thei a, i hmel (leh i mahni inngaihhlutna), i chakna level leh i nunphung a nghawng thei a ni.

Cancer cachexia hi damdawi lam enkawlna bik awm lo mah se, a natna lan chhuah dan tur enkawlna atana pui turin thil i tih theih a awm. Hetiang hi i tawng a nih chuan i cancer enkawltu team hnenah tanpuina dil rawh. Cancer cachexia natna vei harsatna an hrethiam a, an enkawl dan tur chein an theihtawp an chhuah ang.

Hriat reng tur pawimawh ber berte (Take-Home Message) .

• Cancer cachexia hi cancer chhungah ngei pawh a tel lo va, a hranpaa enkawl ngai a ni. Nangmah emaw, i hmangaih tak emaw chuan i taksa rihna a tlahniam a, ei duhna a hloh a, i hah lutuk a nih chuan i doctor nen sawiho rawh.
• Nutrition hi a pawimawh hle. Chaw te tak te, calorie leh protein tamna ei fo te, nutritional supplement chungchanga damdawi lam thurawn lak te hian he natna hi a enkawl thei a ni.
• Nangmah chauh i ni lo. He zinkawng zawh tura pui turin oncologist, nurse, nutritionist, leh palliative care team te an awm a. An thlawpna dawng rawh.
• Rilru hriselna pawh a pawimawh hle. Taksa inthlak danglamna rual hian lungngaihna pawh a awm thei bawk. Hemi chungchangah hian i medical team te nen inbia la, a tul angin tanpuina dawng rawh.

Cancer do hi thil awlsam a ni lo. Hetiang harsatna dang hmachhawn hi a har khawp mai. Mahse, hriatthiamna leh thlawpna dik tak nen chuan heng harsatnate hi hneh theih a ni.

` Cancer cachexia, cancer, bawlhhlawh, taksa ruh khawhral, ​​ei leh in, ei leh in ei loh, cancer enkawlna