Depression emaw, lungkhamna emaw ang chi natna atan doctor-in damdawi a pe tawh che em? Chutiang a nih chuan damdawi `Celexa` emaw `Lexapro` emaw tih i hre tawh mai thei. Hengte hi khawvel hmun hrang hrangah leh kan ramah hian heng natna hrang hrangte damdawi pek chhuah tam ber pahnih an ni. Chuvangin, mi tam takin zawhna an neih chu heng pahnih hi eng nge an danglamna, an inang em, eng ber nge ka tan a dik tih hi a ni. I rilrua rinhlelhna i neih zawng zawng tihfai nan vawiin hian he thu hi sawi ila.
A hmasain Celexa leh Lexapro te hi eng nge an nih kan en ang.
A awlsam zawngin, heng damdawi pahnih hi antidepressants tih pawla mi an ni. A dik tak chuan damdawi pawl bik ``SSRIs`` (Selective Serotonin Reuptake Inhibitors) an tih atanga lo chhuak an ni. A hming hi a buaithlak deuhin a lang thei a, mahse a kalphung erawh a awlsam hle.
Kan thluak chhungah hian thuchah keng chhuak leh hawtu palai an awm tih han ngaihtuah teh. Heng thuchahte hi neurotransmitter kan ti a. Serotonin hi messenger pawimawh tak a ni a, kan mood, behavior, leh memory ang chi thilte control tu a ni. Depression ang chi dinhmunah chuan Serotonin level hi a tlahniam thei a ni.
SSRI te hian an tih chu he messenger serotonin hi a tih zawh hnua a reabsorb nghal vat loh nan a titawp thin. Tichuan serotonin chu thluaka nerve cell-ah rei zawk a awm a. Chu chu "hlim" tih thuchah chu rei zawk active a ni tihna a ni. Hei hi kan mood a lo tha chho tan lai a ni.
Celexa hi damdawi Citalopram brand name a ni a . Lexapro hi damdawi Escitalopram brand name a ni a . An pahnih hian puitlingah major depressive disorder (MDD) enkawl phalsak an ni a, Lexapro hi generalized anxiety disorder (GAD) enkawlna atan pawh pawm a ni bawk.
Okay, chuti a nih chuan eng nge an pahnih inthlauhna lian ber?
Hei hi thil ngaihnawm tak a ni. `Citalopram` (Celexa) leh `Escitalopram` (Lexapro) te hi, chemical hmanga sawi chuan, molecule khata mirror image an ni. Kan kut veilam leh kan kut dinglam ang bawkin. An pahnih hian kut an ni a, mahse an danglam hle. Chemistry-ah chuan hengte hi `enantiomers` an ti a.
- Citalopram (Celexa) hi i sawi "left-handed" leh "right-handed" form pahnih inzawmkhawm a ni.
- Escitalopram (Lexapro) hi an pahnih zingah hian a thawk nasa zawk a, chu chu a bulpui ber chauh atanga siam damdawi a ni tihna a ni a, "kut dinglam" ang chi a ni.
Hei vang hian kan taksaah hian heng damdawi pahnih hnathawh danah hian danglamna tlem a awm a ni.
A awlsam zawngin sawi ila, Escitalopram (Lexapro) hi Citalopram (Celexa) aiin a refined zawk, targeted version ang mai a ni.
A danglamna lian ber ber thenkhat han thlir ila:
- Approved uses: `Citalopram` hi puitling tan chauh depression atan pawm a nih laiin, `Escitalopram` hi puitling leh naupang kum 12 chunglam tan depression atan pawm a ni a, puitling leh naupang kum 7 chunglam tan lungkhamna atan pawm a ni bawk.
- Efficacy: Zirna thenkhatah chuan Escitalopram hian Citalopram aiin depression symptoms control-na kawngah a thawk tha zawk deuh niin an sawi.
- Heartbeat risk: Heng damdawi pahnih hian thinlung electrical activity-ah nghawng tlem a nei thei a ni. Hei hi `QT prolongation` an ti a. Hei hian heart beat pangngai lo awm theihna chance tlem a keng tel a ni. Mahse, he hlauhawmna hi `Escitalopram` aiin `Citalopram` hmang hian a sang deuh a, a bik takin a dose sang zawkah chuan a sang zawk.
Side effect leh thil hriat tur
Heng damdawi pahnih hi chhungkaw khata awm an nih avangin a side effect pawh a inang hle. Mi zawng zawngin kan dawng vek lo a, mahse taksain damdawi a hman thiam deuh deuh avangin rei vak lo hnuah an bo fo thin.
| Celexa leh Lexapro te hian side effect an nei tlangpui | |
|---|---|
| Side effect awm fo thin | |
| Mut harsatna a awm | Chhun lama mut theih loh emaw, zan lama mut theih loh emaw |
| Taksa hah lutuk | Chauhna, luak chhuak |
| Thil awm dan tlangpui dangte | Luak chhuak, lu na, thawk hah lutuk, hmui vawt |
| Digestive system lama harsatna awm thei | Luak chhuak, luak chhuak, chaw ei kham emaw, riltam emaw |
| Sexual function lama harsatna awm thei | Mipat hmeichhiatna lama duhna tlahniam, orgasm thlen harsa, ejaculation tihkhawtlai |
| Rare mahse side effect na tak tak awm thei | |
| Heart rate a inthlak danglam thin | A chunga kan sawi tak `QT Prolongation` condition (Citalopram hmang hian risk a sang deuh deuh) . |
| Thisenah sodium level a tlahniam | ``SIADH'' tih natna avanga lo awm thei a ni a, a bik takin kum 65 chunglamte tan a ni. |
‘Serotonin Syndrome’ hi a bik taka ngaihven a ngai a ni.
Hei hi i hriat chian tur thil a ni . Serotonin Syndrome hi taksaa serotonin awm zat hlauhawm tak a ni. Hei hi damdawi i ei tan tirh emaw, a dose i tihpun emaw, serotonin level tichhe thei damdawi dang (e.g., migraine damdawi thenkhat, antidepressant dang) nena i ei hian a thleng tam ber.
Nangmah emaw, i hriat miin emaw heng symptoms te hi a ruala i tawn chuan damdawi in Emergency Department (ETU) ah kal nghal rawh.
- Restlessness, rilru hahdam lohna
- Nausea, luak chhuak, luak chhuak
- Mitmeng (dilated pupils) a awm
- Tremors, muscle twitching, a nghet lo
- Thaw tam lutuk, khawsik leh khur nasa lutuk
- Buaina nasa tak, hriatna hloh
- Heart rate a sang, thisen sang a sang
- Khawsik, seizures, hriatna hloh
Mahni intihhlum duhna rilruah fimkhur rawh.
Hei pawh hi a pawimawh hle. Antidepressant ei tan atanga kar hmasa berah emaw, a dose thlak emaw hian mahni intihhlum tumna hi a sang deuh thei a, a bik takin thalai leh naupang kum 24 hnuai lam tan chuan a hnuaia symptoms te hi fimkhur hle ang che.
- Depression chu a zual zel a.
- I nun tawp dan tur ngaihtuah.
- Panic attack a awm thin.
- Mu thei lo.
- Restlessness, tharum thawhna, thinrimna.
- Ngaihtuah lova thiltih leh thil danglam tak taka phur chhuak.
Nang emaw i fa emaw hian heng natna lan chhuah dan hi i neih chuan i doctor nen inbia ang che .
He damdawi hi addict i ni thei ang em?
No. Hengte hi ruihhlo ang chi ruihhlo ngawlvei anga ngaih an ni lo. Mahse, buaina a awm.He damdawi hi kar 6 aia rei i ei loh thut chuan taksa lama harsatna i nei thei a ni. Hei hi `antidepressant discontinuation syndrome` an ti a. Mood swing, luak chhuak, leh lungkhamna ang chi symptoms a awm thei.
Chuvangin, eng emaw chhan vangin, doctor rawn hmasa lovin, he damdawi hi ei nghal vat loh tur a ni. Stopping hi doctor thurawn angin tih tur a ni a, zawi zawiin a dose tihtlem a ngai a ni.
Celexa leh Lexapro hman dan dang (Off-label hman dan) .
"Off-label use" tih hian chu natna atana official-a pawm loh natna atana damdawi pek tihna a ni a, mahse doctor-te chuan chu damdawi chu chutiang dinhmun atan chuan a tangkai tih an tawnhriat atang chuan an hre chiang hle. Damdawi pahnih hi natna dang engemaw zat atan hman a ni a, chung zingah chuan:
- Citalopram (Celexa) hman theihna tur dinhmun dang:
- Obsessive Compulsive Disorder (OCD) a awm a, a rilru a buai em em a, a rilru a hah em em bawk a.
- Panic Disorder a ni
- Khawtlang nun lungkhamna (Social Anxiety Disorder) a ni
- Post-traumatic stress disorder (PTSD) a awm a, a rilru a hah lutuk a, a rilru a buai em em bawk.
- A hun hmaa ejaculation
- Escitalopram (Lexapro) hman theihna tur dinhmun dang:
- Khawtlang nun lungkhamna (Social Anxiety Disorder) a ni
- Obsessive-compulsive disorder (OCD) tih a ni a, a rilru a buai em em a, a rilru a hah em em bawk a.
- Panic Disorder a ni
- Menopause nena inzawm natna lan chhuah dan (e.g. hot flashes) .
Chuti a nih chuan, heng pahnih zingah hian eng ber nge thlan tur?
Hei hi zawhna pawimawh ber a ni. Hei hi i doctor-in a enfiah hnua a thutlukna siam tur a ni a, thil tam tak a ngaihtuah hnuah, i natna lan chhuah dan, i kum leh i damdawi lam dinhmun dangte a ngaihtuah ang.
- Anxiety leh depression pahnih i neih chuan Lexapro hi a tha zawk mai thei.
- Lung natna i neih tawh chuan Lexapro hi a tha zawk mai thei a, a chhan chu a hlauhawmna a hniam zawk vang a ni.
- Mi thenkhat tan chuan `Celexa` hian hna a thawk tha hle. Midang tan chuan `Lexapro` hi a tha zawk.
Chuvang chuan hemi chungchang hi Doctor nen inhawng taka sawipui a tha ber. Internet-a i thil chhiar a zirin thutlukna siam suh. I doctor chuan i tan damdawi tha ber leh him ber a thlang ang.
Take-Home Thuchah a ni
- Celexa (Citalopram) leh Lexapro (Escitalopram) te hi SSRI damdawi an ni a, thluaka serotonin level inthlauhna hmangin lungngaihna leh lungkhamna a tidam thei a ni.
- Lexapro hi Celexa hi a refined zawk a, targeted version a nih avangin a hman danah pawh danglamna tlem a awm a, side effect thenkhat pawh a awm bawk.
- He damdawi hi ei tan dawnin mahni intihhlum tumna atan fimkhur a pawimawh hle a , a bik takin kum 24 hnuai lam tan chuan a danglamna i hriat chuan doctor hnenah hrilh nghal rawh.
- Natna khirh tak `Serotonin Syndrome` an tih lan chhuah dan hre reng ang che. Chutiang symptoms i neih chuan damdawi in pan nghal mai tur a ni.
- Damdawi lam thurawn tel lo chuan he damdawi hi ei nghal mai ngai suh. Chutianga tih chuan taksaah harsatna a thlen thei a ni.
- Damdawi dang zawng zawng, vitamin leh damdawi i ei zawng zawngte chu i doctor hnenah hrilh rawh.
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