I fa hian seizures a nei nghal em? Cortical Dysplasia chungchang hi i zir dawn teh ang!

I fa te hian seizure a nei nghal em? A nih loh leh i hriatte hian hetiang epilepsy symptoms hi an nei em? A chang chuan heng thilte hi kan hmuh hian kan hlau takzet thin a ni lawm ni? Hei hi a chhan pakhat chu thluak natna i hriat loh pawh a ni thei. Vawiin hian chutiang dinhmun pakhat kan sawi dawn a, chu chu Cortical Dysplasia . A hming hi a buaithlak deuhin a lang thei a, mahse, i then darh ang u.

Cortical dysplasia tih hi eng nge ni?

A awlsam zawngin, cortical dysplasia hi natna awm lo tak a ni a, seizures a thlen thei a ni . Doctor-te chuan focal cortical dysplasia, emaw (FCD) emaw an ti \hin. "Co-ticle" leh "dys-pla-sia" tia lam tur a ni.

Hetiang dinhmun hian i cerebral cortex a nghawng a ni . Chu chu kan thluak pawn lam layer a ni. Ngaihtuah teh, he cerebral cortex hian thil pawimawh tam tak a thunun a, chu chu kan taksa chetna te, kan ngaihtuahna te, kan thusawi te, kan hriatrengna te, kan finna te, leh kan mizia te hi a ni. Kan computer `CPU` ang a ni.

Damdawi lama "dysplasia" tih hian taksaa cell awm dan pangngai lo a kawk a ni. Chuvangin, cortical dysplasia nei mi pakhatah chuan cerebral cortex, a nih loh leh thluak cell-a cell te hi an lo thang tha lo hle. Hei hi naute chu a pum chhunga a la awm laiin a thleng thin .

Cortical dysplasia chi hrang hrangte chu engte nge ni?

Doctor-te chuan he natna, cortical dysplasia an tih hi chi thum-ah an ṭhen a, chu chu cerebral cortex (lobes) hmun engte nge a nghawng tih emaw, thluaka cell pangngai lo awm dan emaw a zirin a ni.

Type 1 a ni

Hetiang chiah hian i cortex-ah hian cell pangngai lo tak tak, a nih loh leh thluak cell awm dan tur anga inrual lo tak tak a lo awm tawh a ni. Hei hian thluak hmun eng pawh a nghawng thei a ni. Mahse a tam ber chu temporal lobe , thluak beng lam hawia awm, a nih loh leh frontal lobe , hmai lam hawia awm a ni.

Type 2 a ni

Hetiang chi ah hian cerebral cortex chhunga cell te hi a tlangpui aia lian an ni a, a nih loh leh an hmel a danglam hle. He type pahnihna hi type hmasa aiin a complex zawkin a serious deuh bawk. Tin, frontal leh temporal lobes a nghawng tam ber bawk.

Type 3 a ni

Hetiang chi hi cortical dysplasia type 1 emaw type 2 emaw leh thluaka thil danglam dang i neih chuan a thleng thin. Entirnan, thluaka tumor, thisen kalna kawng dik lo, thluaka hliam te nen a awm thei. Thluak hmun a nghawng dan hi tumor awmna hmun emaw, thluak chhiatna hmun emaw a innghat a ni.

Eng nge a lan chhuah dan? Engtin nge i hriat chian?

Cortical dysplasia natnaah chuanA lan chhuah dan ber leh langsar ber chu seizures a ni. Hei hi convulsion kan tih pawh a ni. He epilepsy hi chi hrang hrang a awm thei a:

• Focal Seizures: Hengte hi thluak sir khat atanga tan a ni. Khaw dangah an darh lo. Hetih lai hian i inhnim hrual leh a nghing ang chi thil i tawng mai thei. Mahse chu chu mi zawng zawngin an hmu vek lo. Mak emaw, danglam emaw i ti mai thei.
• Tonic-clonic (Grand Mal) Seizures: Hetiang chi hian thluak sir lehlamah a nghawng a. Hei hi taksa chu thunun theih loha a inher leh a nghing lai a ni. Taksa sir lehlamah a nghawng a ni.
• Infantile Spasms: Hei hi seizure chi khat bik a ni a, naute kum khat hnuai lam chauh a awm thin . Chutah chuan naute chuan an kut, ke leh kawr chu a han phar nghal a, chutah rang takin a hnukkir ​​leh ta a ni. Seizure an nei ang mai a ni. Hei hi ni khatah vawi eng emaw zat a thleng thei.

A pawimawh ber chu heng epileptic seizures te hi dam chhung engtik lai pawhin a intan thei a ni. Mi thenkhat chuan naupan lai atang tawhin, nausen lai atang tawhin an nei tan thin. Mahse mi thenkhat chuan an dam hnuah epileptic seizure hmasa ber an nei thei.

Epilepsy bakah hian symptom dang i nei thei bawk:

• Thil ngaihtuah harsa, rilru hmun khata dah theih lohna .
• Thil thar leh concept thar zir harsa.
• Taksa sir khata thau chak lohna (hemiparesis).

Cortical dysplasia hian thluak taksa insiam dan a nghawng thei bawk. Mahse doctor chuan heng inthlak danglamna te hi MRI scan hmang chauhvin a hmu thei a, chu chu thluak cortex (gray matter) a inthlak danglamna dik tak hriat theihna awmchhun a ni.

Engvangin nge hetiang dinhmun hi a lo awm? A chhan chu eng nge ni?

Cortical dysplasia hi thlahtute atanga lo chhuak a ni a . Chumi awmzia chu genes inthlak danglam avang hian embryonic stage, chu chu naute pum chhunga naute a lo thanlen lai hian thluak hi a thang pangngai lo tihna a ni.

Mahse zirchiangtute chuan eng genetic change nge hetiang thil hi a thlen tih chiang takin an la sawi thei lo. A chhan awm thei te chu an la zirchiang mek a ni.

Mithiam thenkhat chuan Type 2 cortical dysplasia hi MTOR pathway an tih gene a mutation vang niin an ngai . Heng genes te hian kan cell te, a bik takin thluak cell te hi an lo thang lian a, an lo thanglian zel theih nan protein an siam thin. Chuvangin MTOR gene-ah hian mutation a awm chuan cell chi dik lo a tipung thei a ni.

Engtin nge doctor-te hian hei hi an hriat chian? (Diagnosis) tih a ni.

Doctor chuan cortical dysplasia chu specific imaging test hmangin a hmuchhuak thin .

I natna lan chhuah dan leh i hriat tirh lai khan doctor hnenah i hrilh tur a ni. A theih chuan i seizure episodes (i.e. engtin nge an lo intan, eng chen nge an awm, chutih laia thil thleng, etc.) chungchang chipchiar taka pek a pawimawh a, chu information chuan diagnosis siam turin a pui thei che a ni.Doctor chuan hei hi eng chi nge tih a hre thei.

Chumi hnuah chuan doctor chuan i thluak thlalak a la ang a, cerebral cortex-ah hian cell pianzia dik lo emaw, a inmil lo emaw a awm em tih a en ang. Chumi atana an hman theih test te chu:

• `MRI (Magnetic Resonance Imaging):` Hei hian thluak thlalak chiang tak tak a la thei.
• `EEG (Electroencephalogram)`: Hei hian thluak electrical activity a teh a. Hei hian epilepsy lo chhuahna hmun zawn nan a pui a ni.
• `MEG (Magnetoencephalography):` Hei hi thluak hnathawh dan enfiahna test a ni a, `EEG.` ang bawkin
• ``PET scan (Positron Emission Tomography hmanga enfiah)'' tih a ni.
• `SPECT scan (Photon pakhat chauh chhuahna Computed Tomography scan)`

Heng test-te hian an tih vek chu thluak chhunga thil thlengte en mai mai a ni.

Eng enkawlna nge awm?

I doctor chuan i natna lan chhuah dan control nan leh epileptic seizure awm tam lohna tur enkawlna tur a rawt ang che.

Anti-seizure damdawi hmangin an tan fo ang . Mahse hei hi a ni. Cortical dysplasia hian a chang chuan damdawi laka inven theih loh epilepsy a thlen thei bawk. Chu chu epilepsy pangngai aiin damdawi hmanga control a harsa deuh thei tihna a ni . Damdawi hian a tir lamah hna a thawk thei a, mahse hun kal zelah a hlawk lo thei hle.

Ketogenic diet (or keto diet) zawm hian epileptic seizures awm tam lohna a ti tlem thei a ni. Hei hian thau tamna leh carbohydrate tlemna ei tur a huam a ni. Hei hian thluak hian chakna a hmuh dan a tidanglam a ni. Hetiang ei leh in lama inthlak danglamna tur hian dietitian tanpuina i la thei bawk.

Enkawlna dangin i epilepsy chu a control ṭhat loh chuan epilepsy surgery i neih a ngai mai thei . I surgeon chuan eng ang surgery nge i neih dawn tih leh eng nge i beisei tur tih a hrilhfiah ang che.

He natna hi operation hmangin a bo vek thei ang em?

I surgeon chuan he natna hi a paih chhuak thei mai thei. Hei hi thil engemaw zatah a innghat ang:

• Eng ang cortical dysplasia nge i neih?
• Thluak khawiah nge epilepsy hi a intan?
• Dysplasia natna a nasat dan.

Surgeon chuan i thluak hnathawh tichhe lovin chutiang cell pangngai lo chu a la chhuak thei a nih chuan a ropui hle. Heng cell te hi lakchhuah hian seizure awm fo thinna a ti tlem thei a, damdawi ei tur pawh a ti tlem thei bawk. Mahse, a châng chuan chutiang cell pangngai lo zawng zawng chu i paih vek a ngaih hunah chuan thluak tissue ṭha ṭhenkhat pawh i paih chhuak a ngai mai thei.Chutiang a nih chuan, i che theihna te, i hmuh theihna te, leh kawng danga i hriat theihna te chu a nghawng thei a ni. I surgeon chuan he surgery thatna leh that lohna zawng zawng a hrilhfiah ang che a, i tan a tha em tih ngaihtuah turin a pui ang che.

Kawng dang chu heng cell pangngai lote hi thluak hmun dang atanga thliar hran hi a ni. Hei hian chu cell atanga epilepsy darh zel chu a titawp a ni. A châng chuan, surgeon chuan heng cell pangngai lote hi ``laser treatment'' hmangin a tichhia thei bawk a, chu chu thluak surgery pangngai aiin a hlauhawm lo zawk a, a invasive lo zawk bawk .

Cortical dysplasia hi engtiang chiahin nge a nasat?

Thluak tichhe thei dinhmun eng pawh hi a na thei hle. Chutiang natna pakhat chu Cortical dysplasia hi a ni. Mahse, lungngai suh . I doctor chuan i epilepsy leh symptom dangte enkawl dan tur a zawng ang. Zawi zawiin he natna hian i nitin nunah nghawng a neih chu i tihtlem thei tawh ang.

Hei hi a dam kim thei ang em?

A bik takin operation hnuah chuan seizure i nei leh tawh ngai lo mai thei. Chu chu thil lian tak a ni!

Mahse, cortical dysplasia hi khawsik damdawi ei angin "damdawi" a ni lo. Enkawlna hian damdawi hmuh ai chuan symptoms leh epilepsy enkawl hi a ngaih pawimawh zawk a ni .

Hetiang dinhmun nen hian nun chu eng ang nge ni ang?

Cortical dysplasia hian a tlangpuiin thihna thlen thei harsatna a thlen lo va, i dam chhung pawh a nghawng lo. Chu chu chanchin lawmawm tak a ni. Mahse, natna khirh tak i neih fo chuan (a bik takin tonic-clonic seizures) i thih hma deuh theihna a tipung thei a ni . Hei hian hun rei tak chhunga i hriselna a nghawng theih dan tur i ngaihtuah a nih chuan i doctor nen inbia ang che. Ani chuan him leh hrisel taka awm turin a pui thei che a ni.

Engtikah nge Doctor kan hmuh ang?

I doctor chuan eng chen nge i lo haw leh a ngai tih (`follow-up visits`) leh eng test nge i neih a ngai tih a hrilh ang che. A tir lamah, a bik takin enkawl tan hnuah leh operation hma leh operation hnuah doctor pan fo a ngai dawn a ni.

Pawimawh: I rilru natna i neih tam zawk a nih chuan, a nih loh leh a hma aia nasa zawka i lan chuan i doctor hnenah hrilh ngei ang che . I enkawlna chu tihdanglam a ngai tih chhinchhiahna a ni thei a, a nih loh leh damdawi-resistant epilepsy i vei a ni thei bawk.

Emergency-ah eng nge tih tur?

Minute nga aia rei seizure i neih chuan, a zawna seizure vawi tam tak i neih chuan 911 (or i local emergency number) ah call nghal rawh. Hei hi emergency a ni.

I doctor zawh tur zawhna pawimawh

Doctor i hmuh hunah hetiang zawhna hi zawt hreh suh:

• Eng ang cortical dysplasia nge ka neih?
• Epilepsy damdawi hian ka tan hna a thawk dawn em ni?
• Engtikah nge surgery hi ka ngaihtuah ang?
• Eng ang surgery nge ka tan a tha ber?

Thluak chhunga cell tenau tlemte hian engtin nge kan hriselnaah nghawng lian tak a neih theih tih hi ngaihtuah harsa tak a ni. Mahse, i doctor emaw surgeon emaw hnenah zawhna emaw, ngaihtuahna emaw i neih chuan zawt rawh . I thluak leh taksaa thil thleng chungchang i hriat tur zawng zawng an hrilhfiah ang a, i rilru hahdamna tura an tih theihte chu an hrilhfiah ang che.

Kan sawiho tawhte (Take-Home Message) kha hetiang hian kan rawn tarlang e:

Okay, chuti a nih chuan tunah chuan vawiin a kan sawi tawh Cortical Dysplasia kha i hrethiam tawh zawk a ni. Hrereng:

• Hei hi thluak cell te a lo thang tha lo a , epilepsy a thlen thei a ni .
• Hei hi genetic reasons vang pawh a ni thei .
• A lan chhuah dan ber chu epileptic seizure chi hrang hrang a ni .
• Hei hi MRI ang chi test bik hmanga hriat theih a ni.
• Enkawlna kawng hrang hrangte chu damdawi, ketogenic diet, leh a tul chuan operation tih te a ni .
• "Damdawi" kimchang tak sawi ai chuan, a symptoms control a pawimawh zawk .
• Hetiang dinhmun nen hian nun pangngaia nun theih a ni a , mahse epileptic seizures na tak lakah fimkhur a ngai a ni.
• Doctor nena inbiak reng a, a thupek zawm a pawimawh hle.

Nangmah emaw, i hriat miin emaw heng symptoms te hi i neih chuan doctor pan hreh suh la, thurawn la rawh. A hmaa hriatchhuah leh enkawl hian danglamna nasa tak a thlen thei a ni.

` Cortical Dysplasia, Epilepsy, Seizures, Thluak Natna, Focal Cortical Dysplasia, Seizures, Epilepsy, Naupan laia Epilepsy, Genetic Diseases